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World Alzheimer's Day Diagnosing Dementia: See It Sooner The theme for World Alzheimer's Day 2009 is 'Diagnosing Dementia: See It Sooner'. In our materials and activities we will focus on the importance of getting a diagnosis and encouraging medical professionals to recognise the signs of the disease in order for people to receive the treatment they need. Alzheimer’s disease is a brain disorder named for German physician Alois Alzheimer, who first described it in 1906. It is characterized by loss of memory and other intellectual abilities serious enough to interfere with daily life. Alzheimer’s disease accounts for 50 to 70 percent of dementia cases. Developing countries like India, China will be among the countries worst hit by Alzheimer’s disease in the next decade, according to global experts. India had 3.5 million Alzheimer’s/ dementia patients .It is estimated that there are currently about 18 million people worldwide with Alzheimer’s disease,” according to the World Health Organisation. In the year 2000, This figure is projected to nearly double by 2025 to 34 million. Much of this increase will be in the developing countries, and will be due to the ageing population. Currently, more than 50 per cent of people with Alzheimer’s disease live in developing countries and, by 2025, this will be over 70 per cent. Alzheimer’s generally leads to impairment of memory function, communication problems, personality changes, erratic behavior, dependence and loss of control over bodily functions. Alzheimer’s disease doesn’t affect every person the same way, but symptoms normally progress in these stages. Stage 1 (Mild): This stage can last from 2 to 4 years. Early in the illness, those with Alzheimer’s tend to be less energetic and spontaneous. They exhibit minor memory loss and mood swings, and are slow to learn and react. They may become withdrawn, avoid people and new places and prefer the familiar. Individuals become confused, have difficulty organizing and planning, get lost easily and exercise poor judgment. They may have difficulty performing routine tasks, and have trouble communicating and understanding written material. If the person is employed, memory loss may begin to affect job performance. They can become angry and frustrated. Some specific examples of behaviors that people exhibit in this mild stage include: Getting lost Difficulty managing money and paying bills Repetitive questions and conversations Taking longer than usual to finish routine daily tasks Poor judgment and suspiciousness Losing things or misplacing them in odd places Noticeable changes in personality or mood Stage 2 (Moderate): This is generally the longest stage and can last 2 to 10 years. In this stage, the person with Alzheimer’s is clearly becoming disabled. Individuals can still perform simple tasks independently, but may need assistance with more complicated activities. They forget recent events and their personal history, and become more disoriented and disconnected from reality. Memories of the distant past may be confused with the present, and affect the person’s ability to comprehend the current situation, date and time. They may have trouble recognizing familiar people. Speech problems arise and understanding, reading and writing are more difficult, and the individual may invent words. They may no longer be safe alone and can wander. As Alzheimer’s patients become aware of this loss of control, they may become depressed, irritable and restless or apathetic and withdrawn. They may experience sleep disturbances and have more trouble eating, grooming and dressing. Stage 3 (Severe): This stage may last 1 to 3 years. During this final stage, people may lose the ability to feed themselves, speak, recognize people and control bodily functions, such as swallowing or bowel and bladder control. Their memory worsens and may become almost non-existent. They will sleep often and grunting or moaning can be common Constant care is typically necessary. In a weakened physical state, patients may become vulnerable to other illnesses, skin infections, and respiratory problems, particularly when they are unable to move around. TREATMENT Although Alzheimer,s disease is the commonest cause for dementia, it is of utmost importance to look for reversible causes such as thyroid problems, neurological conditions, nutritional deficiencies, etc. There is no drug which can reverse the process, but progression and worsening may be prevented. Vitamin supplements are given to correct nutritional problems. Medications are available to tackle sleep disturbance, suspiciousness, behavioral disturbance like anger outbursts and depression. Drugs such as donepezil, memantine, rivastigmine, galantamine, etc are used to combat memory decline. Care-giver burden is immense in dementia.family members suffer lot of distress due to worsening memory,changing personality and growing dependence in a dementia patient Day-to-day difficulties need to be discussed at length with them. Sharing of burden of primary care giver is very important to prevent psychological stress in family member. Care-giver support groups are present. Support often becomes the mainstay of dementia care.