Download SIRT6, 1-355aa,Human, His tagged, Recombinant, E.coli

SIRT6, 1-355aa
Human, His tagged, Recombinant, E.coli
Cat. No. SIR0901
Cat. No. SIR0951
Size: 0.5 mg
Size: 100 ug
Full name: sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae)
Synonym: sirtuin 6, SIR2L6
NCBI Accession No: NP_057623
Description: The SIRT6 is included in class IV of the sirtuin family, homologs to the yeast Sir2 protein. The
functions of human sirtuins have not yet been determined; however, in yeast sirtuins are known to regulate
epigenetic gene silencing. Also SIRT6, a chromatin-associated protein, appears to be involved in DNA repair.
Recombinant SIRT6, fused to His-tag at N-terminus, was expressed in E.coli and purified by conventional
chromatography techniques.
Form: Liquid in 20 mM Tris-HCl pH 8.0, 10% Glycerol
Molecular Weight: 41 kDa (375 aa)
Purity: > 95% by SDS PAGE
Concentration: 1 mg/ml
Sequences: MGSSHHHHHH SSGLVPRGSH MSVNYAAGLS PYADKGKCGL PEIFDPPEEL ERKVWELARL
VWQSSSVVFH TGAGISTASG IPDFRGPHGV WTMEERGLAP KFDTTFESAR PTQTHMALVQ
LERVGLLRFL VSQNVDGLHV RSGFPRDKLA ELHGNMFVEE CAKCKTQYVR DTVVGTMGLK
ATGRLCTVAK ARGLRACRGE LRDTILDWED SLPDRDLALA DEASRNADLS ITLGTSLQIR
(kDa)
PSGNLPLATK RRGGRLVIVN LQPTKHDRHA DLRIHGYVDE VMTRLMEHLG LEIPAWDGPR
70
VLERALPPLP RPPTPKLEPK EESPTRINGS IPAGPKQEPC AQHNGSEPAS PKRERPTSPA
PHRPPKRVKA KAVPS
40
28
General references:
Michishita E., et al. (2008) Nature. 27;452(7186):492-6
18
Mostoslavsky R., et al. (2006) Cell. 27;124(2):315-29.
13.5
Storage: Store at -20℃. Avoid freeze/thaw cycle
15% SDS-PAGE