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CH. 8 STUDY GUIDE: METABOLISM
KEY WORDS
free energy
activation energy
1st Law of Thermodynamics
enzyme
2nd Law of Thermodynamics
substrate
exergonic
active site
endergonic
induced fit hypothesis
kinetic energy
coenzymes and cofactors
thermal energy
competitive inhibition
equilibrium constant
noncompetitive inhibition
coupled reactions
feedback inhibition
catalyst
cooperativity
ATP
Catabolic
Allosteric regulation
QUESTIONS
1. Cells Preform Three main types of work. List all three and provide an example of
each.
2. Where is the energy from ATP coming from? Be specific and explain.
3. Explain what is meant by activation energy and why the activation-energy barrier
provides stability for high energy molecules.
4. Draw the ATP Cycle.
5. What is a transition state? How does it relate to reaction energy?
6. List and describe the ways in which enzymes lower activation energy.
7. Describe catalysis at the active site.
8. Explain the function and process involved with
a. cofactors
b. inhibitors
9. Explain how toxins and poisons can attach to enzymes and discuss how they can
be so harmful.
10. Describe the process of allosteric regulation. Be specific and include a
description of cooperativity.
11. What is Feedback inhibition? Why is it important to regulation?
12. Draw the graph for an exergonic reaction with and without an enzyme catalyst.
Label the reactants, products, activation energy, transition state, the delta G,
and both axis. Do not forget to give your graph a title.