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MOHD NABIL ABDUL HADI AL-AMA, M.D.
Hospital Address
:
King Abdulaziz University Hospital
C/O Cardiology Unit
P.O.Box 80215, Jeddah 21589
Kingdom of Saudi Arabia
Telephone no.: +966 2 6408272 ext. 18285
Fax no.: +966 2 6408315
Home Address
:
P.O.Box 17277, Jeddah 21484
Kingdom of Saudi Arabia
Telephone no.: +966 2 6400996
Date of Birth
:
September 20, 1958
Place of Birth
:
Damascus, Syria
Citizenship
:
Saudi Arabian
Email Address
:
[email protected]
[email protected]
PRESENT ACADEMIC RANK AND POSITION
 CCU DIRECTOR & CONSULTANT ADULT
INTERVENTIONAL CARDIOLOGIST
 Former Chief of Cardiology Unit, King Abdulaziz University Hospital
 Assistant Professor of Internal Medicine and Cardiology, King
Abdulaziz University Medical School
 Consultant Internist and Consultant Interventional Cardiologist,
King Abdulaziz University Hospital
 Consultant Interventional Cardiologist at Soliman Fakeeh
Hospital.
 Member of Morbidity and Mortality Committee at King
Abdulaziz University Hospital, Jeddah, KSA.
 Member of Cardio Pulmonary Resuscitation Committee at
King Abdulaziz University Hospital, Jeddah, KSA.
EDUCATION
 Graduated in King Abdulaziz University, Jeddah, K.S.A. on June
1982, MB & ChB with very good and honor degree.
 Internship Completion:
 Medicine
(3 months)
 Surgery
(3 months)
 Paediatrics
(2 months)
 Obstetrics and Gynaecology (2 months)
 Elective Haematology
(2 months)
 Senior House Officer (Medical Resident) – Medical Department of
King Abdulaziz University Hospital on July 1983, attending clinics
and in-patients, included in the on-call rota and carried out ward
procedures such as bone marrow aspiration and biopsy, liver
biopsy, pleural aspiration and biopsy, peritoneal tap central
catheter, venous cut down, etc.
 Passed the Canadian Evaluation Examination on March 1985.
 Completed The Medical Residency in McGill University, Canada
from July 1986 to June 1989.
 Worked in Montreal General Hospital, Royal Victoria Hospital,
Jewish General Hospital, Chest Hospital and Saint Mary’s Hospital
in Canada.
 American Board of Internal Medicine Certified on September 1989.
 Royal College of Physicians and Surgeons in Internal Medicine
Certified in 1990 in Internal Medicine.
 Completed The Cardiology Residency in McGill University,
Montreal General Hospital, Royal Victoria Hospital and Jewish
General Hospital from July 1989 and June 1991.
 Completed the Fellowship Training in Invasive and Interventional
Cardiology at McGill University and Jewish General Hospital from
July 1991 to November 1992 and did more than 1000 procedures of
left, right heart catheterizations and PTCA.
BOARD CERTIFICATION
 American Board Of Internal Medicine, 1989
 American Board Of Cardiology, 1995
MEDICAL LICENSURE
 Medical license in Saudi Arabia, 1992
HONORS / AWARDS
 Graduated an Honor Degree at King Abdulaziz University Medical
School in 1982.
 Awarded as an Excellent Teacher (from Vice Dean for Clinical
Department in 1996).
PREVIOUS PROFESSIONAL POSITIONS & APPOINTMENTS
 Locum Consultant Interventional Cardiologist at Military Hospital
in Riyadh.
 Locum Consultant Interventional Cardiologist at Military Hospital
in Jeddah.
 Locum Consultant Cardiologist at Military Hospital in Jeddah
(many times).
 Locum Consultant Intensivist at Military Hospital in Jeddah.
 Locum Consultant Interventional Cardiologist at King Faisal
Specialist Hospital in Jeddah (many times)
 Locum Consultant Cardiologist at National Guard Hospital in
Jeddah (several times)
 Locum Consultant Cardiologist at Al Salama (Private Hospital).
 Locum Consultant Cardiologist at King Faisal Specialist Hospital,
Jeddah (3 times).
 Locum Consultant Cardiologist at National Guard Hospital in
Jeddah (3 times).
 Chairman in International Cardiovascular Conference 2002 (30
April – May). HEPG.
 Chairman in HEPG (International Cardiovascular Conference)
June 2 – 4, 2003
 Chairman (Symposium on Eprosartan – 2 times) in Jeddah.
EDUCATIONAL ACTIVITIES
From 1992 to present
 Assistant Professor and Lecturer of Cardiology Curriculum (4th,
5th and 6th year in Medical School (lectures, curriculum of
Cardiology under Medicine (Hypertension, Ischemic Heart
Disease, Valvular Heart Disease, Congestive Heart Disease,
Myocardial Disease, Introduction to Cardiovascular Exam,
Infective Endocarditis, Pulmonary Embolism and teaching 4th
year Dental School (Cardiology Lectures).
 Medical Rounds to Interns and post graduates residents and
teaching in clinics (medicine and cardiology) for 6th year
students and senior doctors.
 Teaching Clinical sessions and Seminars for 4th, 5th, 6th year,
dental 4th year, house officer and residents and gave Grand
Rounds at University Hospital and in Community hospitals.
 Post Graduate Teaching (monthly basis).
 Responsible for mortality and morbidity for last 3 years.
 Teaching and active member of Jeddah Cardiology Club
(monthly).
INSTITUTIONAL/DEPARTMENTAL & DIVISION
ADMINISTRATIVE RESPONSIBILITIES
 Acting Chairman of Cardiology Unit under the Department of
Medicine at King Abdulaziz University Hospital, Jeddah, KSA.
 Chief of Cardiology Division at United Doctors Hospital
(private sector in evening) previously.
 Consultant Interventional Cardiologist at Soliman Fakeeh
Hospital (private sector).
 Member of Cardio Pulmonary Resuscitation Committee.
 Member of Morbidity and Mortality Committee.
 Reviewer of King Abdulaziz Science Centre in Riyadh.
 Active Member of Jeddah Cardiology Club.
PROFESSIONAL MEMBERSHIP AND SOCIETIES
 Member, American College of Physician, June 1990.
 Fellow, Royal College of Physicians and Surgeons in
Canada, 1990.
 Member, American Heart Association
 Member, Clinical Cardiology Society
 Associate Fellow, American College of Cardiology
 Member, Society of Cardiac Angiography and Interventions
 Member, Saudi Heart Association
 Member, Cardiology and Hypertension Club, Jeddah
 Member of Morbidity and Mortality Committee at King
Abdulaziz University Hospital, Jeddah, KSA.
 Member of Cardio Pulmonary Resuscitation Committee at
King Abdulaziz University Hospital, Jeddah, KSA.
CONTINUING MEDICAL EDUCATION
December 2004
Update of IBS from Dubai
December 2, 2004
Latest Thinking in Acid Reflux
Disease
(Prof. David Armstrong, Mc Master
University, Canada)
May 10, 2004
Myocardial Perfusion Using Definity
(Dr. Roxy, UK)
April 27, 2004
Hypertension: New Trends
Le Meridian Hotel, Jeddah
March 16-18, 2004
The International Conference on
Advances in Internal Medicine
Intercon Hotel, Jeddah
March 7-10, 2004
American Colleges of Cardiology
53rd Annual Scientific Session
March 6, 2004
Burning Question in the Management
of Hypotension and Dyslipidemia
New Orleans Marriott
New Orleans, LA
March 2004
American Heart Association and
American Stroke Association
January 6-8, 2004
The 15th Scientific Session of Saudi
Heart Association
Hotel Intercontinental, Jeddah, KSA
Aug.30-Sept.3, 2003
European Society of Cardiology
Congress 2003
Vienna, Austria
April 14-17, 2003
2nd Conference for Advanced
Medicine
King Abdulaziz University Hospital
Jeddah, KSA
February 24-28,2003
The 30th Annual Meeting of Egyptian
Society of Cardiology
June 2-4, 2003
International Cardiovascular
Conference
King Faisal Specialist Hospital &
Research Center Jeddah, KSA
Aug. 31-Sept. 4, 2002
European Society of Cardiology
Congress 2002
Berlin, Germany
Reaching BP Target in Management
of Hypertension by Prof. Bernard
Weaber.
April 11, 2002
Emerging Data in Hypertensive
Patients with Type II DM by Gerard
Frangin.
March 17-20, 2002
51st Annual Scientific Session
American College of Cardiology
Atlanta, Georgia
March 16, 2002
New Approaches to Treating
Dyslipidemia: Total Lipid
Modification
Atlanta, Georgia
March 16, 2002
Futuristic Issues in the Treatment of
ACS
Atlanta, Georgia
March 16, 2002
Redefining ACS Care in the Era of
Aggressive Revascularization
Duke University School of Medicine
March 5-7, 2002
11th Saudi Neurosciences Symposium
& 3rd Annual Meeting of Saudi
Chapter of Epilepsy.
King Abdulaziz University Hospital
Jeddah, KSA
October 4-5, 2002
Valvular Heart Diseases in the 21st
Century
King Faisal Specialist Hospital &
Research Center Riyadh, KSA
September 1-5, 2001
XXIII Congress of the European
Society of Cardiology
Stockholm, Sweden
Jan. 23-25, 2001
3rd Cardiac Symposium
King Fahd Armed Forces Hospital,
Jeddah, KSA
Oct 17-22, 2000
Transcatheter Cardiovascular
Therapeutics 2000
Washington, DC
Jan. 16-17, 2000
2nd International Cardiac Symposium
Intercontinental Hotel, Jeddah, KSA
March 12-15, 2000
The American College of Cardiology
Anaheim, California
March 07-10, 1999
48th Annual Scientific Session
The American College of Cardiology
New Orleans, Louisiana, USA
March 05, 1999
Best Practices for Optimally Treating
Advanced Heart Failure
New Orleans, Louisiana, USA
March 06, 1999
GPIIb-IIIa Inhibitors in Acute
Coronary Syndrome:
Applying Evidence from Clinical
Trials to Medical Practice
New Orleans, Louisiana, USA
March 06, 1999
Contemporary Strategies for
Achieving BP Goals
University of Miami School of Medicine
Miami, USA
March 06, 1999
Acute Coronary Syndrome:
Quarterbacking and Management
Plan
New Orleans, LA
March 28, 1998
Advanced Heart Failure: Defining,
Debating and Deciding
Atlanta, Georgia
March 28, 1998
Critical Clinical trials in Arrhythmia
Management
Indiana University School of Medicine
March 28, 1998
Myocardial Reperfusion XI:
Concepts & Controversies
Atlanta, Georgia
April 26-29, 1998
The 1st Gulf and Mediterranean
Advanced ECG and Pacemaker
Course
Coral Beach Hotel, Beirut, Lebanon
November 08, 1998
American Heart Associations 71st
Scientific Session
Dallas, Texas
March 29-April 01, 1998
47th Annual Scientific Session
Atlanta, Georgia
March 29, 1998
Angiotensin Receptor Blockers:
New Approaches to Cardiovascular
Disease
March 15, 1997
Stents: Current Clinical Issues
Fullerton, California
March 16-19,1997
46th Annual Scientific Session
The American College of Cardiology
Anaheim, California
March 23, 1996
Stents: A Framework for the Future in
Interventional Cardiology
Texas Heart Institute, Houston, Texas
March 21-23, 1996
Interventional Cardiology
Atlanta, Georgia
September 12, 1996
SYNCOPE: Grand Round
Programme
King Fahd Armed Forces Hospital
Jeddah, KSA
January 15, 1996
Modern Therapeutic Aspects in the
Treatment of Hypertension
Ostra University Hospital
Goteborg, Sweden
March 24-27, 1996
45th Annual Scientific Session
American College of Cardiology
Orlando, Florida
September 6-10, 1995
Update in Cardiology: Cardiovascular
Board Review American College of
Cardiology
Bethesda, Maryland
November 13-16, 1995
American Heart Associations 68th
Scientific Session
Anaheim, California
November 14, 1995
How Will We Manage
Acute Coronary Syndrome?
Duke University Medical Center
Durham, North Carolina
April 11, 1992
Improving Survival and Morbidity in
Heart Failure and Ventricular
Dysfunction
Hyatt Regency, Dallas, Texas
October 19-23, 1992
Review of Cardiology
Harvard Medical School
Boston, Massachusetts
September 9-11, 1992
Complex Coronary Angioplasty and
New Interventional Devices
Saint Luke’s Hospital of Kansas City,
Missouri.
April 12-16, 1992
41st Annual Scientific Session
Dallas, Texas
March 02, 1991
Managing the Patient with
Hyperlipidemia: Current Issues
University of Washington School of
Medicine Seattle, Washington
October 3-6, 1991
Cardiovascular Board Review
Indianapolis, Indiana
March 3-7, 1991
40th Annual Scientific Session
Atlanta, Georgia
March 02, 1991
Managing the Patient with
Hyperlipidemia: Current Issues
University of Washington School of
Medicine Seattle, Washington
November 13-16, 1989
American Heart Associations 62nd
Scientific Session
New Orleans, Louisiana
April 13-16, 1989
70th Annual Session
San Francisco, California
April 14, 1989
Chronic Valvular Regurgitation
Management
April 11, 1989
Critical Care Medicine
April 16, 1989
Dealing with Patients After Serious
Ventricular Arrhythmia
October 28, 1988
A 72 Year Old Woman With Onset of
Confusion
Stanford University School of Medicine
Stanford, California
SEMINARS/WORKSHOPS ATTENDED
March 3-5, 2009
11th KFAFH International Cardiac
Conference 2009
Jeddah, KSA
Nov 16-17, 2008
CT Angio & Cardiac MRI Course
7th International Cardiovascular
Conference 2008
King Faisal Specialist Hospital, Jeddah
May 13-26, 2008
Euro PCR 2008
Barcelona, Spain
Feb 25-29, 2008
35th International Congress of the
Egyptian Society of Cardiology
Cairo, Egypt
Feb 14-26, 2008
Joint Interventional Meeting 2008
Rome, Italy
European Society of Cardiology 2008
Munich
September 1-5, 2007
European Society of Cardiology
Congress 2007
Vienna, Austria
May 22-25, 2007
Euro PCR 2007
Barcelona, Spain
March 24-27, 2007
56th Annual Scientific Session
Innovation in Intervention
New Orleans, USA
Feb 15-17, 2007
Joint Interventional Meeting 2007
Rome, Italy
Feb 6-8, 2007
18th Scientific Session of Saudi Heart
Association
TCT 2007
September 2-5, 2006
World Congress of Cardiology 2006
Barcelona, Spain
May 16-19, 2006
Euro PCR 2006
Paris
April 12-13, 2006
8th International Cardiac Symposium
King Fahad AFH, Jeddah
Jan 31-Feb 2, 2006
17th Scientific Session of the Saudi
Heart Association
Al Khobar, KSA
Innovation in Intervention 2006
American College of Cardiology
1st Conference of Saudi Society of
Internal Medicine
King Abdulaziz Univ. Hospital, Jeddah
3rd Interventional Cardiology Summit
Tunisia
Summit TCT Asia Pacific 2006
Nov 28-Dec 1, 2005
3rd Conference on Advanced Medicine
King Abdulaziz Univ. Hospital, Jeddah
November 22-24, 2005
4th International Cardiovascular
Conference
King Faisal Specialist Hospital, Jeddah
March 6-9, 2005
54th Annual Scientific Session
American College Of Cardiology
Orlando, USA
December 4-6, 2004
Jeddah Cardiovascular Interventional
Symposium
September 5-9, 2004
European Association of the Study of
Diabetes (Munich).
August 31-Sept. 3, 2004
European Society of Cardiology
(Munich).
May 13-16, 2004
Reducing the Burden of
Cardiovascular & Metabolic Disease
along the Cardiovascular Continuum
Istanbul, Turkey
April 29-30, 2004
Advances in Managing Cardiology
and Gastroenterology Disorders
Durrah Beach Resort, Jeddah, KSA
March 16-18, 2004
The International Conference on
Advances in Internal Medicine
Hotel Intercontinental Jeddah, KSA
March 7-10, 2004
53rd Annual Scientific Session
American College of Cardiology
March 6, 2004
Burning Questions in the Management
of Hypertension and Dyslipidemia
New Orleans, LA
January 6-8, 2004
The 15th Scientific Session of Saudi
Heart Association
Hotel Intercontinental, Jeddah, KSA
Dec. 2003
How to read ECG
June 23, 2003
The Value of Early Diagnosis &
Treatment Initiation
of GP II b/III a Antagonist Prior PCI
for Acute Coronary Syndrome
Patients.
Le Meridien Hotel, Jeddah, KSA
June 2-4, 2003
International Cardiovascular
Conference
King Faisal Specialist Hospital &
Research Centre Jeddah, KSA
April 27, 2003
Hypertension: New Trends
Le Meridien Hotel, Jeddah, KSA
April 14-17, 2003
2nd Conference for Advanced
Medicine
King Abdulaziz University Hospital
Jeddah, KSA
February 24-28, 2003
The 30th Annual Meeting of the
Egyptian Society Of Cardiology
Feb. 24-28, 2003
30th Annual Meeting of the Egyptian
Society Of Cardiology
Jan. 7-9, 2003
5th International Cardiac Symposium
King Fahd Armed Forces Hospital
Jeddah, KSA
October 26-28, 2002
3rd Jeddah Cardiovascular
Interventions
Hotel Intercontinental, Jeddah, KSA
October 1, 2002
Update of Thromboembolic Disease
Treatment & Prophylaxis
Le Meridien Hotel, Jeddah, KSA
Aug. 31, 2002
Total Risk Assessment: Advancing the
Management of Cardiovascular
Disease
Aug.-Sept. 2002
ESC Congress 2002
Cardiac Electrophysiology, Detection,
Evaluation and Treatment of High Blood
Cholesterol in Adults
Aug. 31, 2002
Anticoagulation Therapy in Cardiac
Disorder: Scientific Session 2002
Cardiac Imaging
June 23-27, 2002
Practical Implication and
Implementation Of Progress
June 23-27, 2002
Joint ISH/ESH Meeting
Prague, Czech Republic
TCT (Transcatheter Cardiovascular
Therapeutics)
April 30-May 1, 2002
International Cardiovascular
Conference
King Faisal Specialist Hospital &
Research Centre Jeddah, KSA
The 29th Annual International
Conference of the Egyptian Society of
Cardiology
April 2002
Taif 10th Annual Cardiovascular
Conference.
April 11, 2002
Reaching BP Targets in the
Management of Hypertension
Emerging Data in Hypertensive
Patients with Type II Diabetes
Hyatt Regency Hotel, Jeddah, KSA
March 27, 2002
4th King Fahd Armed Forces Hospital
Cardiac Symposium
March 21-24, 2002
The Paris Course on
Revascularization
March 17-20, 2002
51st Annual Scientific Session
American College of Cardiology
March 9, 2002
New Advances in the Management of
Atherothrombosis
Le Meridien Hotel, Jeddah, KSA
January 2, 2002
Hypertension Risk, Systolic or
Diastolic
by Prof. Ahmed Zaki of Cairo University
Hotel Intercontinental, Jeddah, KSA
Nov 10-15, 2001
Basic Life Support & Advanced
Cardiac Life Support Saudi Heart
Association
TCT (Transcatheter Cardiovascular
Therapeutics)
Sept. 1-5, 2001
The Role of Statin in Managing
Patients with Acute Coronary
Syndrome.
June 15, 2001
Endothelial Dysfunction and
Hypertension:
Nebivolol, an Innovative Therapeutic
Approach
June 15-19, 2001
Novel Calcium Antagonist Evidence
on Blood Pressure Control and Target
Organ Protection.
May 22-25, 2001
The Paris Course on
Revascularization
May 1-4, 2001
An Integrated Approach to Optimize
Cardiovascular Care
Le Meridien Hotel, Jeddah, KSA
April 11, 2001
Taif 9th Annual Cardiovascular
Conference
April 23-26, 2001
International Conference on
Advanced Medicine
King Abdulaziz University Hospital,
Jeddah, KSA
Transcatheter Cardiovascular
Therapeutics 2001
January 23-25, 2001
The Joint Meeting of the 12th Scientific
Session of the Saudi Heart Association
and the
3rd Cardiac Symposium of King Fahd
Armed Forces Hospital
Jeddah, KSA
January 28, 2001
New Trends in the Management of
Hyperlipidemia
& Cardiovascular Risks
Crowne Plaza Hotel, Jeddah, KSA
November 11, 2000
The Diagnosis and Treatment of
Pulmonary Embolism
Marriott Hotel, Jeddah
October 4-5, 2000
Valvular Heart Diseases in the 21st
Century
King Faisal Specialist Hospital &
Research Centre Riyadh, KSA
Oct. 18, 2000
Harmonizing Mechanical and
Pharmacological Approaches in Acute
Ischemic Syndrome.
October 4-5, 2000
Valvular Heart Diseases in the 21st
Century
September 26, 2000
Anti-leukotrienes & Current Trends
in Asthma Therapy
Hotel Intercontinental, Jeddah, KSA
September 19, 2000
Angiotensin II Antagonism: Benefits
Beyond Blood Pressure Control
Holiday Inn Crowne Plaza, Jeddah, KSA
May 29-June 3, 2000
10th European Meeting on
Hypertension
Goteborg, Sweden
April 18, 2000
Gastro-Oesophageal Reflux Disease
Marriott Hotel, Jeddah
March 12-15, 2000
49th Annual Scientific Session
American College of Cardiology
February 4-6, 2000
Winning The Race Against
Cardiovascular Disease
Progression: The Contribution
Adrenergic Blockade
of
Feb. 4-6, 2000
Winning the Race against
Cardiovascular Disease Progression:
The Contribution of Adrenergic
Blockade.
January 16-17, 2000
2nd International Cardiac Symposium
(ECHOCARDIOGRAPHY)
King Fahd Armed Forces Hospital
Jeddah, KSA
November 16, 1999
Symposium on Cardiology
Johns Hopkins University Hospital
November 16, 1999
4th Scientific Symposium on
Cardiology
Hotel Intercontinental, Jeddah, KSA
October 20-22, 1999
The Role and Potential of Statin
Sharm El-Sheikh, Egypt
October 3, 1999
Hypertension and Elevated Heart
Rate between Theory & Practice by
Prof Halzgneze of Germany
Holiday Inn Crowne Plaza Hotel,
Jeddah, KSA
October 6, 1999
The Role of Angiotension II Receptor
Blockers In the Management of the
Cardiovascular Disease In the 21st
Century by Prof. Tomas Vagen & Prof.
Louis Rimlope
Holiday Inn, Jeddah, KSA
October 12-13, 1999
1st Live International Symposium on
Cardiovascular Catheter Intervention
Dr. Erfan & Bagedo Hospital
Jeddah, KSA
September 26, 1999
Treatment Approach for Coronary
Heart Disease Patients by Dr. Ole
Feergman of USA & Dr. Mogens
Larsen of Denmark
Lailaty Ballroom, Jeddah
September 14, 1999
Role of Angiotensin II Antagonists in
Control of Hypertension & Vital
Organ Protection
Lailaty Hall, Jeddah, KSA
December 2, 1998
Valvular Heart Disease
King Fahd Armed Forces Hospital,
Jeddah, KSA
Jeddah Cardiovascular Intervention
Jeddah Heart Institute
Jeddah, KSA
An Integrated Approach to Optimize
Cardiovascular Care
October 21-24, 1998
9th International Congress of
Cardiology and Cardiac Surgery
Portemilio, Kaslik, Lebanon
April 26-29, 1998
The 1st Gulf & Mediterranean
Advanced ECG and Pacemaker
Course
Coral Beach Hotel, Beirut, Lebanon
February 22-27, 1998
The 25th Anniversary of the Egyptian
Society of Cardiology
Cairo, Egypt
June 17, 1997
Novel Approaches in Treating
Hypertension and Renal Disease Via
Blockade of the Renin-Angiotensin
System.
February 18-20, 1997
8th Scientific Session
Saudi Heart Association
Jeddah, KSA
June 25-July 6, 1995
5th & 6th year Final Clinical
Examination
King Abdulaziz University Hospital
Jeddah, KSA
January 24-26, 1995
6th Scientific Session
Jeddah, KSA
January 25-27, 1994
5th Scientific Session
Saudi Heart Association
Jeddah, KSA
November 8-11, 1993
66th Scientific Session
American Heart Association
Atlanta, Georgia
October 5-6, 1993
Update on Endocrinology & Metabolic
Diseases
King Khalid National Guard Hospital
Jeddah, KSA
May 12-13, 1993
International Symposium on Current
Concepts & Controversies in
Cardiology
King Khalid National Guard Hospital
Jeddah, KSA
April 20-21, 1993
International Symposium on Renal
Disease And Hypertension
King Khalid National Guard Hospital
Jeddah, KSA
April 11-12, 1993
Current Trends in the Management of
Coronary Artery Disease
Armed Forces Cardiac Center, Riyadh,
KSA
March 1989
W Mandell: Cardiac Arrhythmias
November 17, 1985
The Role of Beta Blockers in
Myocardial Infarction
Jeddah, KSA
Sept. 6-10, 1995
Update in Cardiology
Cardiovascular Board Review
Percutaneous Coronary Intervention after
Subcutaneous Enoxaparin Pretreatment
in Patients with Unstable Angina Pectoris.
Cardiac Electrophysiology:
Detection, Evaluation and Treatment of
Increase Blood Cholesterol in Adults.
Prevention of Disease Progression
Throughout the Cardiovascular
Continuum.
Controlling Cardiac Arrhythmias
Evolving Perspective in Atrial
Fibrillation.
Board Review Course in Cardiovascular
Disease
Electrical Therapy for Cardiac
Arrhythmias.
PUBLICATIONS
 Heart Rate Variability in Patients with Mitral Stenosis: A Study of 20
Cases from King Abdulaziz University Hospital
 Time-Domain Analysis of Heart Rate Variability in Diabetic Patients
with and without Autonomic Neuropathy.
 Homocysteine Level and other Biochemical Parameters in
Cardiovascular Disease Patients with Diabetes Mellitus.
 Using Hemoglobine spectra as an Indicator for some diseases.
 Multivalvular Infective Endocardistis in a Tetrology of Fallot.
 Dietary Vitamin A may be a Cardiovascular Risk Factor in a Saudi
Population.
 The Impact of the Genetic Polymorphism of Paraoxosonase Gene
(PON 1) on the Incidence of Coronary Vascular Disease in Saudi
Population.
 High Cardiovascular Risk in Young Saudi Males: Cardiovascular Risk
Factor, Diet and Inflammatory Markers.
 Relationship between Indices of Iron status and Coronary Risk Factors
including Diabetes and the Metabolic Syndrome in Saudi Subjects
without overt Coronary Disease.
 Trace Elements status in Saudi patients with Established
Atherosclerosis.
 At present, I am involved in Monthly Research Projects like left
carotid artery thickness, CAD, LAD, Hypertension, Pregnancy,
Anticoagulation & Hypertension, Atrial Fibrillation and CHF.
Journal of King Abdulaziz University
Volume, 21, No. 1,
pp, March 2009-12-22
"USING HEMOGLOBINE SPECTRA AS AN INDICATOR FOR SOME
DISEASES
Dear Dr. Mohammed Nabil Al Ama
I am very pleased to inform you that your manuscripts entitle:
"Using Hemoglobin Spectra as an Indicator for Some Diseases"
Which has been submitted to the King Abdul Aziz Bulletin "Science" has been
accepted for publication in the journal and will appear in (Vol.21, No.
1, pp, March 2009)
Prof. Abdullah M. Asiri
Editor – in – chief
Signature
Chemistry of Science
King Abdul-Aziz University
P.O.Box 80203
Saudi Arabia
Tel. +02-695 2293
Fax. +02-695 2292
E – mail: [email protected]
www.kau.edu.sa/aasiri2
Willy InterScience: JOURNALS:
Volume 25 Issue 1, Pages 88-90
Echocardiography
MULTIVALVULAR INFECTIVE ENDOCARDITIS IN A TETRALOGY OF
FALLOT
Ashraf M. Anwar, M.D., Youssef F, M.Nosir, Ph.D., M.D., Aref Ajam, M.R.C.P.,
Maimoona Mushtaq, F.R.C.P., Mohammed N. Alama, F.R.C.P.c,
Hassan Chamsi-Pasha, F.R.C.P., (Lond) F.R.C.P. (Glasg), F.R.C.P.I.,
F.A.C.C.
ABSTRACT
Infective endocarditis (IE) is still a problem in patients with adult congenital heart
disease. Tetrology of Fallot (TOF) is one of the most important manifestations of
congenital heart disease, which carries a high risk for the development of IE. We
present an 18 year – old male with TOF complicated by an aggressive from of IE
involving all cardiac valves.
Med Sci Monit,
Volume 2003; 9(12) CR 523-527
HOMOCYSTEINE LEVEL AND OTHER BIOCHEMICAL
PARAMETERS IN CARDIOVASCULAR DISEASES PATIENTS
WITH DIABETES MELLITUS
Mohammed Ajabnoor, Mohammed Al Ama, Zainy Banjar, Adel Abdul Rafee,
Salah Sheweita
Abstract Summary:
Back ground:
Atherosclerosis is the main cause of cardiovascular morbidity and mortality in may
countries. It is believed that hyperhomocysteinemia is a risk factor for premature
atherosclerosis and other cardiovascular diseases (CVD) in both men and women.
Material/Methods:
Plasma samples from 31 non-CVD and 51 CVD patients with diabetes were studied.
Informed consent was obtained from all subject. Blood samples were collected after
overnight fasting. Total homocysteine (H [e]), the levels of high and low density
lipoproteins (HDL, LDL), total cholesterol, urea and creatinine were determined
with commercial kits.
Results:
The levels of homocysteine, vitamin B12` creatinine and urea in CVD patients were
significantly higher than those found in the normal subjects. On the other hand, the
levels of folic acid, HDL and LDL were lower in CVD patients than in normal
subjects. Interestingly, a linear relationship was found between the levels of
homocysteine and total cholesterol in CVD samples, whereas no such linear
relationship was present in normal subject.
Conclusions:
The level of homocysteine in plasma is known to be mainly dependent on the levels
of folic acid and vitamin B12. However, in the present study the level of
homocysteine in the plasma of CVD patients is dependent on the level of folic acid
and not on the level of vitamin B12. Subjects with high homocysteine levels should b
advised to consume a folic acid-fortified diet in order to reduce the homocysteine
level in patients at high risk for cardiovascular disease.
Key words: atherosclerosis. Homocysteine. Cholesterol. Diabetes
Annals of Saudi Medicine,
Vol.22, Nos. 5-6 2002
THE TIME DOMAIN ANALYSIS OF HEART RATE VARIABILITY IN DIABETIC
PATIENTS WITH AND WITHOUT AUTONOMIC NEUROPATHY
Awdah Al-Hazimi, PhD; Nabil Al-Ama, MRCP; Ahmad Syiamic, PhD; Reem Qosti, BSc, Khidir
Abdel-Galil,PhD
Abstract;
The normal heart rate is determined by dynamic interaction between the spontaneous cardiac impulse
generated by the sinoatrial (SA) node and conflicting influences of the sympathetic and
parasympathetic nervous systems on the conducting tissue of the heart. The rate of spontaneous
depolarization of the SA node is itself affected by its metabolic milieu and in the longer term, by
hormonal influences. Normal resting heart rate is maintained by the tonic influence of the
parasympathetic vagus nerve, and acceleration of the heart rate is affected both by the inhibition of
vagal influence and the stimulation of the sympathetic nervous system. The activity of the autonomic
is also governed by moment-to-moment changes in blood pressure and respiration, which alter heart
rate continuously. The resultant heart rate is the summation of all these influences and thus inherently
unpredictable on a beat-to-beat basis.
Recently advances in technology have enabled accurate recordings and the automated analysis
of 24-hour ECG to detect beat-to-beat variability, providing not only more detailed, but much more
accurate and precise information than the earlier tests.1
Heart rate variability (HRV) decreases with age,2 and shows a circadian variation, being maximum
during sleep.3 It is also rate dependent, the heart rate showing more variability at lower heart rates.
The loss of this beat-to-beat variability is a sign of disease.
It has long been known that cardiovascular autonomic diabetic neuropathy (CADN) is
associated with a loss of heart rate variability.4,5. These Patients have a poor cardiovascular
prognosis,6,7 with a 5 year mortality greater than 50%.8 Some of this may be attributed to micro- or
macrovascular disease,9 however, a recent study has shown the relatively poor prognosis of patients
with CADN in the absence of clinically detectable micro- or macrovascular donditions.10 Clinically
detectable autonomic failure is usually evident many years or decades after the onset of diabetes. It is
likely that these patients develop subtle deficit in HRV much earlier, and these may include
diminution in time-domain analysis. Detection of such changes may be used a markers of pathology,
particularly to study the benefits of therapeutic interventions. Thus, the aim of this work was to study
HRV in diabetic patients with clinical and sub-clinical autonomic neuropathy (AN), and to determine
whether HRV in patients with sub-clinical AN is abnormal in comparison to normal control.
Subject and Method
Following Local Ethical Committee approval, we studied 10 consecutive, newly diagnosed
non-insulin dependent diabetics mellitus (NIDDM), 10 NIDDM with autonomic diabetic neuropathy
(AND), and 10 age-matched normal control (Table 1). Informed consent was obtained from each
subject. The patients were selected from King Abdulaziz University Hospital in Jeddah, Saudi
Arabia, under supervision of a medical consultant. The analysis of HRV was done in the Department
Physiology. We found no gender differences in any measure of HRV (data not shown), which is
consistent with previous published work.10 All subjects had no evidence of pre-existing
cardiovascular disease, were normotensive, had no previous history of ill health, and were taking no
regular medication except standard diabetic therapy.
24-Hour ECG Recording
The 24-hour electrocardiogram (ECG) recordings were carried out using a two-channel
tracker (DEL MAR Holter System). One channel records the ECG signal and the second channel
records a time signal generated by the recorder. The time signal is used to make correction for
vitiations in tape speed. Individuals went about normal daily activities. A new cassette tape and
battery were used or each recording.
The electrodes were positioned in standard positions over the precordium. Reply, QRS
detention and measurement of the RR interval was performed using DEL MAR ECG Analyzer. After
analogue to digital conversion, a digital computer stored the time intervals (ms) between successive R
waves as the interval tachogram (time series).
Asia Pacific J Clin Nutr
DIETARY VITAMIN A MAY BE A CARDIOVASCULAR RISK FACTOR IN
A SAUDI POPULATION
Eman M Alissa BSc1,2, Suhad M Bahjri BSc, PhD1, Nabeel Al –ama,
MD,FRCP(c)1,4
Waqar H Ahmed MD, MS1,3, Bryan Starkey BSc, PhD2 and Gordon A A Ferns MD.
FRCP Path.2
Traditional risk factors do not appear to explain fully the variation in the incidence of
the cardiovascular diseases (CVD). Epidemiological studies have not been entirely
consistent with regard to the relationship between antioxidant vitamin intake and
CVD and there appears to be little data on this relationship in non-Caucasian
populations. This study aimed to investigate the dietary intake of vitamin A, C, and
vitamin E, and carotenoids, serum concentrations of vitamin E and A and indices of
lipid peroxidation were measured in male Saudi patients with established CVD and
age-matched controls. We assessed the dietary intakes of vitamins A, C, and E and
carotenoids, by a food frequency questionnaire. Serum vitamins A and E
concentrations were measured by HPLC, in 130 Saudi male subjects with established
CVD, and 130 age-matched controls. We also determined serum lipid profiles (total
cholesterol, triglycerides, HDL-c, LDL-c), lipoprotein (a), oxidized LDL, and serum
lipid peroxide concentrations. Diabetes mellitus (p<0.0001), a positive smoking habit
(p<0.0001) and hypertension (p<0.05) were more prevent among CVD patients.
Levels of dietary vitamin E and A were also significantly higher among cases. In
conditional logistic regression analysis, the most significant characteristics
differentiating CVD patients from controls were diabetes mellitus )Odds ratio 2.49 DI
I.42-4.37, p<0.001), total fat intake (Odds ratio 1.02,CI 1.01-1.03,p<0.01), serum
vitamin A (Odds ratio 0.72, CI 0.53-0.99, p<0.05), and the vitamin A/total fat intake
ratio (Odds ratio 1.04, DI 1.01-1.06, p<0.01). in a Saudi population, smoking habit
and hypertension were significantly more common among patients with CVD.
Multivariate analysis showed that dietary total fat and vitamin A and the presence of
diabetes mellitus were independent coronary risk factors. This is the first report of a
potentially deleterious effect of dietary vitamin A in a non-Caucasian population.
However it is possible that unidentified residual confounding factors may account for
this finding.
Key words: vitamin A, C, and E, coronary disease, risk factors, lipid peroxides,
dietary antioxidant vitamin intake, oxidative stress, coronary atherosclerosis, Saudi
Arabia, Jeddah.
Tanta Medical Science Journal
Vol.(32),No.(1),January 2008:pp 113-123
THE IMPACT OF THE GENETIC POLYMORPHISM OF
RAOXOSONASE GENE (PON1) ON THE INCIDENCE OF
CORONARY VASCULAR DISEASE IN SAUDI POPULATION
Zeiny. M. Banjr(1), Adil. A. Abdulrafee(1), Nabil Alamaa(2) & Osama. A. Gaber(1)
Department of Clinical Biochemistry (1) and Internal Medicine(2) , Faculty of Medicine, King
Abdulaziz University, Jeddah, Kingdom of Saudi Arabia
ABSTRACT:
___________________________________________________________________________________
Background/Aim: Cardiovascular diseases as being one of the major causes of
morbidity and mortality drags attention for the study of their pathogenesis which
seems multifactorial including habitual, environmental and genetic causes. The major
cause for atherosclerosis is deposition of oxidized lipoproteins in the blood vessel.
Paraoxonase (PON1), an enzyme tightly linked to HDL plays an important role in
decreasing the susceptibility of LDL-cholesterol for oxidation, thus minimizing
atherosclerotic changes in the blood vessels. Paraoxonase activity in the serum alone
is not a determining factor for this role. This function is also controlled and affected
by many polymorphisms occurring in the PONI1 gene. The aim of this study was to
evaluate the effect of one of this genetic polymorphism (at position 192) on
cardiovascular disease in Saudi population.
Subjects & Methods: This study included 169 subjects (100 cases and 69 controls).
For all participants in the study Paraoxonase activity, lipid profile, Apo A-1 and
genetic polymorphism was done.
Results: The percentage distribution of this genetic polymorphism differs in Saudi
population than those observed in previous studies as in Mexican population and is
more similar to those in Japanese population. There was no significant difference in
the genetic distribution between control and CVD groups. The activity of Paraoxonase
was lower in the CVD group compared to the control; also there was no significant
correlation between this genetic polymorphism and the lipid composition of the blood.
Conclusion: PON1 activities toward paraoxon are lower in subject with CVD than in
control subjects regardless of the PON1 genotype although the PON1 activity is much
lower in RR genotype than QQ genotype.
Key word:
Paraoxonase, Polymorphism, HDL, Atherosclerosis, Coronary.
_____________________________________________________________________
ELSEVIER
SCIENCE @ DIRECT
Clinica Chimica Acta 365 (2006) 288-296
HIGH CARDIOVASCULAR RISK IN YOUNG SAUDI MALES:
CARDIOVACULAR RISK FACTOR, DIET AND INFLAMMATORY
MARKERS
Eman M. Alissa a,b*, Suhad M. Bahjri a, Nabeel Al-ama a,d,
Waqar H. Ahmed a,c , Gordon A.A. Ferns b
Abstract
Background: The relationship between coronary risk score (CRS), individual coronary
risk factors and the serum inflammatory markers, high sensitivity C-reactive protein
(hsCRP), ceruloplasmin (Cp), and soluble intercellular adhesion molecule-1 (sICAM-1)
was studied in 140 Saudi males without clinically evident coronary heart disease (CHD).
Methods: One hundred forty subjects without clinically evident CHD were categorized
into age tertiles. Demographic data together with an estimate of CRS using Framingham
and PROCAM algorithms were obtained, and serum lipid profile, glucose, hsCRP,
sICAM-1, and Cp were measured. Macronutrient intake was assessed by a questionnaire,
the relationship between CRS, biochemical markers and diet was assessed by univariate
and multivariate analysis.
Results: There was no significant difference in median hsCRP, sICAM-1 or Cp between
the age groups. Serum Cp was positively associated with age (r=0.224,p<0.01) and FRS
score (r=0.174, p<0.05). Serum sICAM-1 was negatively associated with PROCAM
score (r=-0.183,p<0.05).
sICAM-1 was positively associated with HDL cholesterol (r=-0.36,p<0.0001) among
non diabetic and negatively associated (r=-0.397,p<0.05) among diabetic subjects. Age
and dietary intake of saturated fatty acids together explained 7.9% of the variation in
serum Cp levels in a stepwise multiple regression model. Similarly 6.5% of the variation
in serum sICAM-1 level was explained by the total cholesterol/HDL-C ratio. The
youngest tertile of the group (<30y) had the highest dietary intake of energy, fat and
saturated fatty acids (p<0.05), and also had a high prevalence of obesity, smoking and
sedentary lifestyle.
Conclusion: We have demonstrated that there is a high prevalence of coronary risk
factors and poor dietary intake within a Saudi male population and that dietary factors
are associated with serum sICAM-1 and ceruloplasmin but not hsCRP concentrations in
this group.
© 2005 Elsevier B.V. All rights reserved.
Keywords: Inflammatory markers; C-reactive protein; Soluble adhesion molecules;
Ceruloplasmin; Coronary risk factors; Saudi males; Dietary fatty acids.
ELSEVIER Journal of Trace Elements in Medicine and Biology
21 (2007) 242-254
REALTIONSHIP BETWEEN INDICES OF IRON STATUS AND CORONARY
RISK FACTORS INCLUDING DIABETES AND THE METABOLIC
SYNDROME IN SAUDI SUBJECTS WITHOUT OVERT CORONARY
DISEASE
Eman M. Alissaa, Waqar H. Ahmeda,c , Nabeel Al-amaa,d, Gordon A.A. Fernsb
_____________________________________________________________________
Abstract
There have been inconsistent reports o the relationship between iron status and
coronary artery diseases (CAD), and little data on this relationship in non-Caucasian
populations.
We assessed dietary iron by questionnaire and measured serum iron and ferritin
levels in 270 Saudi male subjects without established CAD, 130 of whom were
angiogram negative. Serum lipid profile, glucose, high sensitivity-C reactive protein
(hs-CRP), serum soluble intercellular adhesion molecules-1 (sICAM-1), and
ceruloplasmin were measured in all subjects.
The angiogram negative patients, had lower serum ferritin (p<0.05) and iron
(p<0.0001) levels than the 140 subjects without reported cardiovascular diseases
(CVD). Serum iron correlated with serum triglycerides (p<0.0001) and total
cholesterol (p<0.05) levels for this latter group and the groups combined. Serum
ferritin correlated with serum total cholesterol and low-density lipoprotein (LDL)cholesterol in the combined group (p<0.05), and was correlated with blood glucose
and serum LDL-cholesterol (p<0.05) in the subjects without reported CVD. After
adjustment for confounding variables, serum iron levels remained a correlated
significantly with cholesterol intake and fasting serum total cholesterol. Dietary iron
was significantly related to dietary cholesterol fiber, age, smoking habits, and total
cholesterol level.
Hence, indices of iron status were related to several coronary risk factors in the
Saudi population.
© 2007 Elsevier GmbH. All rights reserved.
Keywords: Ferritin; Saudi Arabia; Coronary risk factors; Metabolic syndrome;
Diabetic mellitus
ELSEVIER
Journal of Trace Elements in Medicine and Biology EPIDEMIOLOGY
20 (2006) 105-114
TRACE ELEMENT STATUS IN SAUDI PATIENTS WITH ESTABLISHED
ATHEROSCLEROSIS
Eman M. Alissaa,b, Suhad M. Bahjria , Waqar H. Ahmeda,c , Nabeel Al-amaa,d,
Gordon A.A. Fernsb
Abstract
Background: Traditional coronary risk factors do not fully explain variation in the
incidence of cardiovascular disease (CVD). Epidemiological studies have implicated
perturbations in selenium, copper and zinc metabolism in the etiology of CVD.
However, these studies have been principally undertaken in Caucasian populations, in
whom trace element intake is generally sufficient.
Method: Diabetes mellitus, positive serum and urine selenium, copper, and zinc;
and superoxide dismutase, glutathione peroxidase, and dismutase, glutathione
peroxidase, and lipid peroxide concentrations in 130 Saudi male subject with
established CVD, and 130 age-matched control.
Results: Diabetes mellitus, positive smoking habit (p<0.0001 for both), and
hypertension (p<0.05) were more prevalent among CVD patients. Urinary copper
(p<0.0001) and zinc (p<0.05) were higher among controls. Serum selenium
concentration were lower among CVD patients (p<0.0001), and a high proportion
(52%) had selenium levels below 79ug/L compared to controls (22%) (p<0.0001).
Conditional logistic regression analysis, showed the characteristics differentiating
CVD patients from controls were serum zinc (odds ratio (OR) 0.92, confidence
interval (CI) 0.85-0.99, p<0.05) , serum copper/zinc ratio (OR 0.31, CI 0.10-0.96),
serum selenium (OR 0.07, CI 0.02-0.031, p<0.0001), and urine selenium (OR 3.34, CI
1.40-7.99, p<0.01).
Conclusion: Measures of trace metals status appear to be associated with the risk of
atherosclerosis in a Saudi male population.
Keywords: Copper; Zinc; Selenium; Atherosclerosis; Saudi Arabia
Tanta Medical Science Journal
Vol. (32), No. (1), January 2006, pp 113-123
HEART RATE VARIABILITY IN PATIENTS WITH MITRAL STENOSIS.
20 CASES FROM KING ABDULAZIZ UNIVERSITY HOSPITAL
Name: Mohammed Nabil Al Ama
Country: Kingdom of Saudi Arabia
City: Jeddah
P.O.Box: 17277
Tel: 6408272
Department: Cardiology (Medicine)
College/Directorate: King Abdulaziz University
Country of birth: Syria
Date of birth: 1958
Nationality: SAUDI
Languages: Arabic-English
Date of Graduation: 1991
Highest Degree: AMERICAN BOARD OF INTERNAL MEDICINE (USA)
Academic Title: Associate Professor
Abstract
1-Heart Rate Variability in patients with Mitral Stenosis. A study of 20 cases from
King Abdulaziz University Hospital
2- Time Domain Analysis of Heart Rate Variability in Diabetic Patients with and
without autonomic Neuropathy
3- Homocysteine Level and other Parameters in Cardiovascular Disease Patients With
Diabetes Mellitus
4- The impact of genetic polymorphism of Paraoxonase gene (PON1) on the
incidence of coronary vascular diseases in Saudi population.
Zeiny.M.Banjar, Adil. A. Abdulrafee, Nabil Alamaa and Osama A, Gaber.
 Tanta Medical Science Journal , Vol. (32), No. (1), January 2006, pp 113-123