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Answer Key to Pharm Practice Exam 1) C-tx symptoms of hypoglycemia first, the pt’s blood sugar will have dropped too much with the insulin 2) A-NPH is naturally cloudy 3) B-only form of insulin avail as U500 (comes in its own syringe) 4) D-rapid acting insulin should not be given IV 5) C-glucagon has no TE on hypoglycemia of starvation 6) A-atropine causes dry mouth big-time 7) B-patients should never abruptly stop taking Dilantin; it should be tapered 6wks to months if pt is being taken off the drug 8) C-ototoxicity 9) D-too much Lasix causes hyponatremia bc it increases excretion of Na 10) C-beta 1 blockers and CCB’s have the same effects 11) A-constipation is an AE of Verapamil and is severe in elderly 12) B-definition of Bruxism. EPS is extra pyramidal sx’s (Parkinson’s type sx’s); serotonin syndrome sx’s are agitation, confusion, disorientation, anxiety, hallucinations, poor concentration…); withdrawal syndrome sx’s are dizziness, HA, nausea, anxiety, tremors…and you can only get withdrawal syndrome when ur taken off Prozac, which was not the case in the question 13) C-Ace inhibitors are the ‘prils’ 14) B-Valsartan won’t cause cough or hyperkalemia like Ramipril 15) C-red/orange urine is normal for pt’s tx with Warfarin and pt should not cease drug tx if this happens 16) D-Vit B12 requires IF to be absorbed, so pt will need it for life if they lack IF 17) A-foods, like cereal and milk, decrease absorption of Feosol 18) B-Atropine dries you out so you would not take it with another med that also dries you out 19) B-Mucomyst is the antidote for Tylenol OD 20) A-pt should sit up 30min after taking to prevent esophagitis; Fosamax should only be taken with water, no food. Chewing or sucking on it can lead to build up in esophagus>esophagitis 21) A-1970 22) B-definition of ADME 23) C-definition of potency 24) B-polypharmacy pt’s always at highest risk for toxicity due to D-D interactions 25) B-ETOH has higher effects on women, boo. Overwt pt’s need larger doses to achieve same TE 26) C-always assess pt for ADR’s first if med error has been made, then notify charge nurse, physician, and fill out incident report 27) D-glucocorticoids in high doses=anti-inflammatory/immunosuppressant effects; not useful in tx anaphylaxis (only good for mild allergic rxns like bee stings), decrease absorption of Ca++ in the gut, AE can be growth retardation in kids 28) D-Keflex globally causes all those things except it decreases PTT (clotting time) -->bleeding 29) A-Vanco is ototoxic. Can cause red/flushed skin, Red Man Syndrome, and should not be infused rapidly-->Red Man Syndrome (is reversible though) 30) A-Sumycin causes photosensitivity. Food will help w/GI disturbances, milk decreases absorption of it, one of Sumycin’s uses is to tx periodontal disease 31) B-aplastic anemia is a result from bone marrow depression, an AE of chloramphenicol. Your body won’t have enough RBC’s, WBC’s, or platelets which leads to aplastic anemia (it is a heavy duty, broad spectrum antibiotic!) 32) C-Narcan is an opioid antagonist-it competes with opiates in the body to tx abuse of opioids 33) B-Gentamicin can cause injury to ears, kidneys, and causes weak/flaccid muscles. 34) B-Amphotericin B should only be given slow IV bc it’s absorbed poorly in the GI tract and can cause phlebitis at the IV site if infused rapidly 35) B-Benadryl/Tylenol/increased water intake 36) A-onychomycoses (fungus in nailbeds); tx lasts 6mo 37) D-tx for HSV 1 and 2 38) C-topical use of acyclovir can cause stinging at application site 39) B-Peg-Intron causes flu like symptoms (it is used for organ transplant pt’s) 40) C-women on Ribavirin should not take it if pregnant and should double dose BCP 41) C-anticholinergics=cant see, cant pee, cant poop, cant get it up, cant walk, cant spit… 42) C-always store Epi pens in a dark place at room temp 43) C-tissue necrosis can occur if Epi leaks out of a vein into surrounding tissues 44) A-metoprolol is doc for htn in diabetics bc it is a selective beta blocker, meaning it does not have AE of bronchoconstriction or glycogenolysis 45) D-Ca++ and beta 1 RECEPTORS normally increase HR and force of contractions 46) B-codeine is used to suppress cough, and is often combined with other meds to tx cough 47) B-demerol is doc for pregnants bc it has a low placental cross 48) D-heart failure. Inderal tx’s HTN, causes bradycardia, has nothing to do w/glaucoma 49) B-no limit to CNS depression. Used to tx seizures, sleep disorders, mania. 50) C-insomnia. Used to tx anxiety, insomnia, muscle spasms, ETOH withdrawal 51) A-rebound cardiac excitation (ST and VT). Used to tx HTN, doesn’t cause it. Causes reduced CO. nothing to do with pheochromocytoma 52) D-cox 2 inhibitor, 2nd generation (selective to cox 2 only) 53) A-salicyclism is tinnitus caused by Aspirin OD 54) A-Diazepam (Valium) is used to tx insomnia, muscle spasms, ETOH withdrawal, anxiety 55) B-PPI’s are often abused and should be given 30 min before meals (Ex: Prilosec) 56) B-Tagamet DOC 57) D-dulcolax can cause bowel eruption in S/P bowel surgery pts bc it stimulates gut motility 58) A-keep patient well hydrated bc Metamucil is a bulk-forming laxative and can form a mass in the GI if patient is not well hydrated=LOTS OF WATER! 59) C-mucinex increases flow of resp. tract secretions 60) A-neo Synephrine causes vasoconstriction of blood vessels in the nose reduced swelling in nose reduced drainage 62) B-sudafed is widely abused and is kept behind pharmacy counters 63) D-Tagamet decreases hepatic metabolism of other drugs (increases blood levels of other drugs); Pepsid does not 64) B-cephs are most widely used antibiotics. They cause hypersensitivity/anaphylaxis, they are similar to PCN’s (bactericidal), they do not have a sig. increased ability to cross BBB although some 4th gen cephs do have the ability to cross it 65) C-Dilantin drug levels can be measured by looking at drug levels in the plasma 66)A- nystagmus=rocking eyes caused by dilantin