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MCB 169: Fall 2015 Sept 3rd Sept 8th Sept. 10th Sept 15th Sept. 17th Sept 22nd Sept 24th Sept 29th Oct 1st Oct 6th Oct 8th Oct 13th Oct 15th Oct. 20th Oct 22st Oct 27th Oct 29th Nov 3rd Nov 5th Nov 10th: Nov 12th Nov17th Nov 19th Nov 24th Nov 26th Dec 1st Dec 3rd Overview: a dangerous world (Chapter 1) Innate Immunity I (Chapters 2 and 4) Innate immunity II (Chapters 2 and 4) Antibodies and antigens (Chapter 5) Antigen receptors and MHC molecules (Chapter 6) Antigen presentation (Chapter 6) Ig genes and the generation of diversity (Chapter 8) B cell development and tolerance (Chapter 8) T cell development and tolerance (Chapter 8) B cell activation (Chapter 7 and 11) Affinity Maturation/ Isotype Switching (Chap: 11) T cell activation (Chapters 7 and 9) Lymphocyte homing ( Chapter 3) CMI I: T helper cells and Tregs (Chapter 10) MID-TERM EXAMINATION CMI II: CD8 T cells and NK cells (Chapter 10) Effector mechanisms of humoral immunity (Ch 12) Tolerance and Autoimmunity (Chapter 14) Mucosal and Epithelial Immunity Blood groups and transplantation (Chapter 16) Allergies, Immune injury (Chapters 18 and 19) Immunology of HIV/AIDS (Chapter 20) Immune responses to tumors (Chs15/17) Immunity to Microbes THANKSGIVING Apoptosis/immunological memory (Chs 9 and 11) Primary Immunodeficiency disorders (Chapter 20) Grade Breakdown: Section Participation Problem set Mid term Finals Pillai Pillai Pillai Pillai Pillai Pillai Pillai Pillai Pillai Pillai Pillai Pillai von Andrian Pillai Pillai Pillai Pillai Pillai Pillai Pillai Alter Dougan Pillai Pillai Pillai 20% 20% 30% 30% Textbook Cellular and Molecular Immunology 8th edition (or 7th), Abbas et al. (e-version also available on Inkling) Office Hours Prof. Pillai will be available on Wednesday afternoons on the HMS Longwood campus - Modell Center 2nd floor from 12.30 to 1.30 and 2.30 to 3.30 PM. For the rest of the week it will be possible to schedule meetings at his office at the Ragon Institute in Kendall Square in Cambridge by e-mail: [email protected]