Download Genetics Study Guide Final Exam

Genetics Final Exam Study Guide
Molecular Genetics
Information flow in molecular genetics (sequence relationship between DNA, RNA and
protein),
Open Reading Frame and how to use the genetic code
Mutations -- missense (conservative, non-conservative), nonsense, silent and frame-shift,
Loss-of-function, Gain-of-function.
Mechanisms of mutagenesis
Genetic Testing (RFLP analysis)
Cytogenetics
Meiosis (normal meiosis and non-disjunction meiosis)
Meiotic basis for segregation and independent assortment.
X chromosome inactivation
Transmission Genetics
Principles of segregation and independent assortment
Pedigree analysis (autosomal and X-linked)
Multiple alleles
Co-dominance
Recessive epistasis
Linkage and mapping (two- point crosses, pedigree analysis)
Population Genetics
Calculating genotype and allele frequencies of a population
Testing populations for genetic equilibrium
Estimating the frequency of heterozygotes (or carriers) in a population.
DNA Fingerprinting
Developmental Genetics
Hox genes
Cloning by SCNT