Evolutionary dynamics of nematode operons
... inferred only when all of its constituent genes were still present in the genome, because we are interested in the separation of constituent genes of an operon, rather than gene loss. However, there is a small probability that although all of the constituent genes are present, some of them have beco ...
... inferred only when all of its constituent genes were still present in the genome, because we are interested in the separation of constituent genes of an operon, rather than gene loss. However, there is a small probability that although all of the constituent genes are present, some of them have beco ...
Single-stranded heteroduplex intermediates in l Red homologous
... the Pi protein must be present so that the R6K plasmid is replicating. On the other hand, if replication is only required to amplify the initiating recombination complex, then the insertion of the colE1 origin should suffice. The two DNAs were co-electroporated into an E. coli strain that contained ...
... the Pi protein must be present so that the R6K plasmid is replicating. On the other hand, if replication is only required to amplify the initiating recombination complex, then the insertion of the colE1 origin should suffice. The two DNAs were co-electroporated into an E. coli strain that contained ...
Gene Section MLL (myeloid/lymphoid or
... t(X;11)(q13;q23)/ANLL, T-ALL --> MLL/AFX1 t(X;11)(q22;q23)/ANLL --> MLL/Septin2 t(1;11)(p32;q23)/ALL --> MLL/AF1p t(1;11)(q21;q23)/ANLL --> MLL/AF1q t(2;11)(q11;q23)/MDS --> MLL/LAF4 t(3;11)(p21;q23)/t-ANLL --> MLL/AF3p21 t(3;11)(q25;q23)/t-ANLL --> MLL/GMPS ins(5;11)(q31;q13q23)/ALL --> MLL/AF5q31 ...
... t(X;11)(q13;q23)/ANLL, T-ALL --> MLL/AFX1 t(X;11)(q22;q23)/ANLL --> MLL/Septin2 t(1;11)(p32;q23)/ALL --> MLL/AF1p t(1;11)(q21;q23)/ANLL --> MLL/AF1q t(2;11)(q11;q23)/MDS --> MLL/LAF4 t(3;11)(p21;q23)/t-ANLL --> MLL/AF3p21 t(3;11)(q25;q23)/t-ANLL --> MLL/GMPS ins(5;11)(q31;q13q23)/ALL --> MLL/AF5q31 ...
MOLECULAR RECOGNITION AND RESPONSE IN POLLEN AND
... buds, which are unable to reject self pollen, and the increase in expression during subsequent flower development coincides with the acquisition of SI by the pistil. (This expression pattern makes it possible in some self-incompatible species to obtain plants homozygous for a particular S-haplotype ...
... buds, which are unable to reject self pollen, and the increase in expression during subsequent flower development coincides with the acquisition of SI by the pistil. (This expression pattern makes it possible in some self-incompatible species to obtain plants homozygous for a particular S-haplotype ...
Nucleic Acids Research
... phytohormones. Added cytokinins reverse the effect of the tmr mutation; added auxins reverse the effect of the tms mutation on the morphology of normal cultured tumor tissue (14). From these results, it is evident that the products of the tms and tmr loci are involved in the regulation of phytohormo ...
... phytohormones. Added cytokinins reverse the effect of the tmr mutation; added auxins reverse the effect of the tms mutation on the morphology of normal cultured tumor tissue (14). From these results, it is evident that the products of the tms and tmr loci are involved in the regulation of phytohormo ...
Identity-by-descent filtering of exome sequence data for disease
... differs between two adjacent positions t −1 and t is the recombination fraction θ. Recombination frequencies depend on the chromosomal region and on sex. In other words, the inheritance vectors arise during meiosis from an inhomogeneous Markov process with position-dependent transition probabilities ...
... differs between two adjacent positions t −1 and t is the recombination fraction θ. Recombination frequencies depend on the chromosomal region and on sex. In other words, the inheritance vectors arise during meiosis from an inhomogeneous Markov process with position-dependent transition probabilities ...
Development of a repressible mycobacterial
... these tools proved to be quite useful, they have the disadvantage that Tc functions as an inducer of gene expression and has therefore to be removed to silence the gene under investigation. For this reason Guo et al. (13) developed a modified system using a mutated TetR able to bind tetO only in the ...
... these tools proved to be quite useful, they have the disadvantage that Tc functions as an inducer of gene expression and has therefore to be removed to silence the gene under investigation. For this reason Guo et al. (13) developed a modified system using a mutated TetR able to bind tetO only in the ...
View PDF - OSU Biochemistry and Molecular Biology
... required for appendage formation, encodes a homeobox transcription factor and is one of the high-level executives regulated by Hox proteins. The area of Dll expression in the embryo (shown as grey patches) corresponds to sites where in the course of development imaginal discs and, subsequently, appe ...
... required for appendage formation, encodes a homeobox transcription factor and is one of the high-level executives regulated by Hox proteins. The area of Dll expression in the embryo (shown as grey patches) corresponds to sites where in the course of development imaginal discs and, subsequently, appe ...
PCB Biodegradation and bphA1 Gene Expression Induced by
... The aerobic degradation of PCB by microbe is necessary to be regulated by using specific inducers to open a degradation pathway. Some organic carbons such as biphenyl, salicylic acid, and plant secondary metabolites (e.g., coumarin, carvone, naringin, etc.) have been shown to influence aerobic PCB r ...
... The aerobic degradation of PCB by microbe is necessary to be regulated by using specific inducers to open a degradation pathway. Some organic carbons such as biphenyl, salicylic acid, and plant secondary metabolites (e.g., coumarin, carvone, naringin, etc.) have been shown to influence aerobic PCB r ...
MOLECULAR BIOLOGY OF FRUIT MATURATION AND
... A clarification of the common genetic regulatory elements that are shared among climacteric and non-climacteric species is central to a full understanding of fruit ripening. Such primary regulators of fruit maturation might be shared by, or at least related to, those that regulate maturation of dehi ...
... A clarification of the common genetic regulatory elements that are shared among climacteric and non-climacteric species is central to a full understanding of fruit ripening. Such primary regulators of fruit maturation might be shared by, or at least related to, those that regulate maturation of dehi ...
Phylogenetic analysis of three complete gap
... transfer of small molecules (<1 kDa) between neighboring cells [1]. Cell –cell communication via gap junctions is critical for normal cellular function and homeostasis as evidenced by the wide variety of connexin mutations that lead to human disease [2]. A single connexin protein folds into four con ...
... transfer of small molecules (<1 kDa) between neighboring cells [1]. Cell –cell communication via gap junctions is critical for normal cellular function and homeostasis as evidenced by the wide variety of connexin mutations that lead to human disease [2]. A single connexin protein folds into four con ...
Hox patterning of the vertebrate axial skeleton
... plan, wherein the identity of parasegments along the AP axis normally expressing a specific Hox gene are transformed to the identity of parasegments immediately anterior to the loss-offunction region (Lewis, 1963, 1978). The reciprocal gain-of-function experiments in Drosophila, in which more posteri ...
... plan, wherein the identity of parasegments along the AP axis normally expressing a specific Hox gene are transformed to the identity of parasegments immediately anterior to the loss-offunction region (Lewis, 1963, 1978). The reciprocal gain-of-function experiments in Drosophila, in which more posteri ...
Intellectual property rights and innovation: Evidence from
... Celera’s IP on subsequent scientific research and product development outcomes. The first research design tests whether genes that ever had Celera’s IP differ in subsequent innovation, as of 2009, from genes initially sequenced by the public effort. Any observed differences in this cross-section spe ...
... Celera’s IP on subsequent scientific research and product development outcomes. The first research design tests whether genes that ever had Celera’s IP differ in subsequent innovation, as of 2009, from genes initially sequenced by the public effort. Any observed differences in this cross-section spe ...
SALSA MLPA probemix P018-F1 SHOX - MRC
... Léri-Weill Dyschondrosteosis (LWD) is a dominant skeletal disorder characterized by short stature and distinct bone anomalies. Deletions of the SHOX gene and/or regulatory elements downstream of SHOX, are detected in approximately 60% of LWD patients (Benito-Sanz et al. 2006; Huber et al. 2006; Fuka ...
... Léri-Weill Dyschondrosteosis (LWD) is a dominant skeletal disorder characterized by short stature and distinct bone anomalies. Deletions of the SHOX gene and/or regulatory elements downstream of SHOX, are detected in approximately 60% of LWD patients (Benito-Sanz et al. 2006; Huber et al. 2006; Fuka ...
SVPaper050711
... SVs and the SV’s ancestral state, was used to infer the likely mechanism of formation for simple SVs. To obtain breakpoint sequence, we performed de novo local assembly at 80.3% of deletions23. Comparison of 1,314 predicted deletion breakpoints to the breakpoint delineated by PCR and sequencing (Sup ...
... SVs and the SV’s ancestral state, was used to infer the likely mechanism of formation for simple SVs. To obtain breakpoint sequence, we performed de novo local assembly at 80.3% of deletions23. Comparison of 1,314 predicted deletion breakpoints to the breakpoint delineated by PCR and sequencing (Sup ...
The molecular basis of human retinal and vitreoretinal
... Monogenic diseases of the retina and vitreous affect approximately 1 in 2000 individuals, or more than 2 million people worldwide. Consequences for affected individuals are variable and can range from legal blindness in the most severe forms of retinal degenerations (Leber congenital amaurosis, LCA) ...
... Monogenic diseases of the retina and vitreous affect approximately 1 in 2000 individuals, or more than 2 million people worldwide. Consequences for affected individuals are variable and can range from legal blindness in the most severe forms of retinal degenerations (Leber congenital amaurosis, LCA) ...
Genetic studies of psoriasis and psoriatic arthritis
... joints. Psoriasis affects approximately 2-3 % of the Caucasian population and about 30 % of all psoriasis patients develop psoriatic arthritis. Both diseases have a strong genetic component but are also affected by environmental factors and are thus regarded as multifactorial. A major genetic factor ...
... joints. Psoriasis affects approximately 2-3 % of the Caucasian population and about 30 % of all psoriasis patients develop psoriatic arthritis. Both diseases have a strong genetic component but are also affected by environmental factors and are thus regarded as multifactorial. A major genetic factor ...
000927 - JHBS Revista Cientifica 3ª edicao
... L. monocytogenes can be misidentified by gram-staindetermined morphology as Corynebacterium spp, which is often regarded as a contaminant, especially when the colonies grown from the clinical sample are scarce. In our region, L. monocytogenes is not always included in automated systems and is not of ...
... L. monocytogenes can be misidentified by gram-staindetermined morphology as Corynebacterium spp, which is often regarded as a contaminant, especially when the colonies grown from the clinical sample are scarce. In our region, L. monocytogenes is not always included in automated systems and is not of ...
Convergent Evolution in the Genetic Basis of Müllerian Mimicry in
... from a genomic BAC library and identified a strong candidate for determination of lateral plate phenotypes. Identifying genetic markers tightly linked to the plate morph locus was achieved by screening stickleback crosses with amplified fragment length polymorphism (AFLP) markers, enabling markers l ...
... from a genomic BAC library and identified a strong candidate for determination of lateral plate phenotypes. Identifying genetic markers tightly linked to the plate morph locus was achieved by screening stickleback crosses with amplified fragment length polymorphism (AFLP) markers, enabling markers l ...
Convergent Evolution in the Genetic Basis of Müllerian
... from a genomic BAC library and identified a strong candidate for determination of lateral plate phenotypes. Identifying genetic markers tightly linked to the plate morph locus was achieved by screening stickleback crosses with amplified fragment length polymorphism (AFLP) markers, enabling markers l ...
... from a genomic BAC library and identified a strong candidate for determination of lateral plate phenotypes. Identifying genetic markers tightly linked to the plate morph locus was achieved by screening stickleback crosses with amplified fragment length polymorphism (AFLP) markers, enabling markers l ...
genomebiology.com
... revealed that TEs are less likely to be fixed within transcribed regions relative to orthologous regions in human and mouse [16]. In G. gallus, D. rerio and C. intestinalis, 33.2%, 47.3% and 39.4% of TEs reside within introns, respectively, whereas in the human genome, approximately 60% of TEs resid ...
... revealed that TEs are less likely to be fixed within transcribed regions relative to orthologous regions in human and mouse [16]. In G. gallus, D. rerio and C. intestinalis, 33.2%, 47.3% and 39.4% of TEs reside within introns, respectively, whereas in the human genome, approximately 60% of TEs resid ...
PHI-Canto video tutorial slides - PHI-base
... Annotated 2 PHI phenotypes with evidence codes and relevant extensions I have added a GO molecular function annotation term with evidence code to the MAP1 gene ...
... Annotated 2 PHI phenotypes with evidence codes and relevant extensions I have added a GO molecular function annotation term with evidence code to the MAP1 gene ...
Synonymous codons are not the same with
... To find whether the different synonymous codon composition is resulting in faster translation due to translation kinetics but not due to different mRNA structure, Yu et al. performed in vitro translation with yeast cell extract. Codon usage bias is different between N. crassa and yeast: the preferre ...
... To find whether the different synonymous codon composition is resulting in faster translation due to translation kinetics but not due to different mRNA structure, Yu et al. performed in vitro translation with yeast cell extract. Codon usage bias is different between N. crassa and yeast: the preferre ...
Disruption and aberrant expression of HMGA2 as a
... accessory proteins, often referred to as architectural transcription factors. 1–3 They are low molecular mass nuclear proteins of about 100 amino acids, which each possess three copies of a nine amino-acid motif (AT-hook) that interacts with the minor groove of many promoter and enhancer DNA regulat ...
... accessory proteins, often referred to as architectural transcription factors. 1–3 They are low molecular mass nuclear proteins of about 100 amino acids, which each possess three copies of a nine amino-acid motif (AT-hook) that interacts with the minor groove of many promoter and enhancer DNA regulat ...
Kinds of gene rearrangement
... nothing to mark the breakage points. Without such accuracy, the crossing over would be unequal; which it is not (with one exception). Also the conditions required for a break are the reverse of those for a join. A second hypothesis, stated in full by BATESON in 1911, demanded selective division of c ...
... nothing to mark the breakage points. Without such accuracy, the crossing over would be unequal; which it is not (with one exception). Also the conditions required for a break are the reverse of those for a join. A second hypothesis, stated in full by BATESON in 1911, demanded selective division of c ...