Chapter 1 Introduction
... 1.To know the research object and purpose of histology. 2 .To know the common research techniques of histology. 3. To know the relationship between the cubic morphology with varieties of sections. 【Main content and Distribution of teaching time】 1. The research contents and the situation in medicine ...
... 1.To know the research object and purpose of histology. 2 .To know the common research techniques of histology. 3. To know the relationship between the cubic morphology with varieties of sections. 【Main content and Distribution of teaching time】 1. The research contents and the situation in medicine ...
s sanoFi avent 4 -6' Lt ~,,' 2i
... in the approved platinum-based drugs and',i other platinum agents reported in the literature, the amine-based nitrogen-platinum bond is con~sidered inert and remains bound to platinum during chemical reactions . The leaving group(s) are substituted through chemical reactions with biological molecule ...
... in the approved platinum-based drugs and',i other platinum agents reported in the literature, the amine-based nitrogen-platinum bond is con~sidered inert and remains bound to platinum during chemical reactions . The leaving group(s) are substituted through chemical reactions with biological molecule ...
a review on the pharmacology of embelia ribes burm.f.
... drugs that are vital for treatment of disorders such as cancer or diabetes, one such classical example is the modified form of the compound acetylsalicylic acid more commonly known as aspirin was the first modern drug that was born from the nature’s medicine, the bark of the willow tree. It is no ac ...
... drugs that are vital for treatment of disorders such as cancer or diabetes, one such classical example is the modified form of the compound acetylsalicylic acid more commonly known as aspirin was the first modern drug that was born from the nature’s medicine, the bark of the willow tree. It is no ac ...
Hit discovery and hit-to-lead approaches
... suitable high-throughput assay can be developed for HTS. Novel ideas generated by information on small molecules reported in the literature are potentially the fastest entry to new leads for validated targets. In addition, in silico methods remain an attractive option for prioritizing structures for ...
... suitable high-throughput assay can be developed for HTS. Novel ideas generated by information on small molecules reported in the literature are potentially the fastest entry to new leads for validated targets. In addition, in silico methods remain an attractive option for prioritizing structures for ...
STAPHYLOCOCCUS AUREUS - DO WE REALLY HAVE TO LIVE
... Moreover, it is crucial to select the right pharmaceutical formulation of the appropriate drug. For instance, equal doses of benzylpenicillin G, procain penicillin and benzathine penicillin will produce completely different penicillin plasma concentrations (19). Consequently, the results of in vitro ...
... Moreover, it is crucial to select the right pharmaceutical formulation of the appropriate drug. For instance, equal doses of benzylpenicillin G, procain penicillin and benzathine penicillin will produce completely different penicillin plasma concentrations (19). Consequently, the results of in vitro ...
Amoxicillin/clavulanate - a broad spectrum antimicrobial
... The UK Centre on Safety of Medicines advised that amoxicillin/clavulanate should only be used for infections thought to be due to amoxicillin resistant strains and that treatment length should match the indication (usually < 14 days). This bulletin outlines some of the indications for which amox ...
... The UK Centre on Safety of Medicines advised that amoxicillin/clavulanate should only be used for infections thought to be due to amoxicillin resistant strains and that treatment length should match the indication (usually < 14 days). This bulletin outlines some of the indications for which amox ...
NON-STEROIDAL ANTIINFLAMMATORY DRUGS (NSAIDS)
... Structure and Chemistry: Some of the most useful NSAIDs are structurally derived from arylacetic acids. These compounds are often referred to as the “profens” based on the suffix of the prototype member, ibuprofen. Like the salicylates these agents are all strong organic acids (pKa = 3-5)and thus fo ...
... Structure and Chemistry: Some of the most useful NSAIDs are structurally derived from arylacetic acids. These compounds are often referred to as the “profens” based on the suffix of the prototype member, ibuprofen. Like the salicylates these agents are all strong organic acids (pKa = 3-5)and thus fo ...
Bicillin LA
... in the liver, skin, and intestines. Penicillin G penetrates into all other tissues and the spinal fluid to a lesser degree. With normal kidney ...
... in the liver, skin, and intestines. Penicillin G penetrates into all other tissues and the spinal fluid to a lesser degree. With normal kidney ...
lactuca sativa linn. - Journal of Pharmaceutical and Scientific
... Plant origin drugs have played a vital role in the prevention and treatment of diseases in Unani medicine and it becomes popular day by day due to its low cost and less adverse effect. One such drug is Tukhme kahu (Seeds) belong to the family Asteraceae is an important herbal drugs which have hypogl ...
... Plant origin drugs have played a vital role in the prevention and treatment of diseases in Unani medicine and it becomes popular day by day due to its low cost and less adverse effect. One such drug is Tukhme kahu (Seeds) belong to the family Asteraceae is an important herbal drugs which have hypogl ...
Review Article Amla (Emblica officinalis) – Medicinal Food and
... Amla helps scavenge free radicals. Amla is powerful food for the brain. Studies show that Amla helps lower cholesterol. Amla also helps maintain the functioning of the liver, increases hemoglobin, red blood cell count. It is useful for Cough, Bronchitis and Asthma. Amla cleanses the mouth, strengthe ...
... Amla helps scavenge free radicals. Amla is powerful food for the brain. Studies show that Amla helps lower cholesterol. Amla also helps maintain the functioning of the liver, increases hemoglobin, red blood cell count. It is useful for Cough, Bronchitis and Asthma. Amla cleanses the mouth, strengthe ...
PHARMACOLOGICAL SCREENING AND EVALUATION OF ANTI-PEPTIC ULCER PROPERTY OF Research Article
... Review of the available literature revealed that majority of the antiulcer studies so far conducted have used pylorus ligation model [13]. The different constituents like flavonoids, tannins, phenols, steroids, saponins, alkaloids and glycosides have been reported to be responsible for anti ulcer ac ...
... Review of the available literature revealed that majority of the antiulcer studies so far conducted have used pylorus ligation model [13]. The different constituents like flavonoids, tannins, phenols, steroids, saponins, alkaloids and glycosides have been reported to be responsible for anti ulcer ac ...
Mark Jansen, M.D.
... Reducing emergence of resistance: Use only when necessary. Limit treatment to < 6 mos. Stop if no additional improvement noted Give choice a minimum of 6 to 8 weeks (length of time-microcomedone to mature clinical lesion) ...
... Reducing emergence of resistance: Use only when necessary. Limit treatment to < 6 mos. Stop if no additional improvement noted Give choice a minimum of 6 to 8 weeks (length of time-microcomedone to mature clinical lesion) ...
Antidepressant specificity of serotonin transporter suggested by three LeuT–SSRI structures Zheng Zhou
... Sertraline and fluoxetine are selective serotonin re-uptake inhibitors (SSRIs) that are widely prescribed to treat depression. They exert their effects by inhibiting the presynaptic plasma membrane serotonin transporter (SERT). All SSRIs possess halogen atoms at specific positions, which are key det ...
... Sertraline and fluoxetine are selective serotonin re-uptake inhibitors (SSRIs) that are widely prescribed to treat depression. They exert their effects by inhibiting the presynaptic plasma membrane serotonin transporter (SERT). All SSRIs possess halogen atoms at specific positions, which are key det ...
Cheryl Lopate, MS, DVM Diplomate, American College of
... In the early stages of this disease, there is only inflammation in the wall of the uterus (called subacute endometritis). At this point, there are no outward signs of disease in the bitch. With repeated cycles, this inflammation gets worse and worse until finally there are enough bacteria and inflam ...
... In the early stages of this disease, there is only inflammation in the wall of the uterus (called subacute endometritis). At this point, there are no outward signs of disease in the bitch. With repeated cycles, this inflammation gets worse and worse until finally there are enough bacteria and inflam ...
STABILITY OF CEFPIROME SULFATE IN AQUEOUS SOLUTIONS
... Cefpirome sulfate (CPS) (Fig. 1) is a new fourth-generation cephalosporin for parenteral administration. It is an oxime-type cephem with a 2amino-thiazolylmethoxyimino group in the side chain at position 7, while at position 3 it is cyclopentapyridine. Those elements in structures are responsible fo ...
... Cefpirome sulfate (CPS) (Fig. 1) is a new fourth-generation cephalosporin for parenteral administration. It is an oxime-type cephem with a 2amino-thiazolylmethoxyimino group in the side chain at position 7, while at position 3 it is cyclopentapyridine. Those elements in structures are responsible fo ...
eth obota ical ad pharmacological study
... from 200, 300 and 500 mg/kg. The 300 mg/kg dose has shown a decrease in the paw oedema volume by 48.5% as compared to the standard drug, Phenybutazone (57.6%) within 4 hours after administration[71].Besides, the doses of 200 mg/kg and 300 mg/kg produced significant reduction in granuloma weight, whe ...
... from 200, 300 and 500 mg/kg. The 300 mg/kg dose has shown a decrease in the paw oedema volume by 48.5% as compared to the standard drug, Phenybutazone (57.6%) within 4 hours after administration[71].Besides, the doses of 200 mg/kg and 300 mg/kg produced significant reduction in granuloma weight, whe ...
Preventing and Curing Infectious Diseases: Carbohydrate
... countries nut increasingly in industrialized nations as well. We are in danger of entering a “post-antibiotic” era as the drugs against many infectious diseases are becoming inactive due to the emergence of resistance. Most pathogens including bacteria, fungi, viruses and protozoa carry unique glyca ...
... countries nut increasingly in industrialized nations as well. We are in danger of entering a “post-antibiotic” era as the drugs against many infectious diseases are becoming inactive due to the emergence of resistance. Most pathogens including bacteria, fungi, viruses and protozoa carry unique glyca ...
THESPESIA POPULNEA LINN. Review Article MOHINI A. PHANSE*,
... chemical and spectral data. The screening for anti-psoriatic activity was carried out by topical application of different extracts and isolated compounds. The successive pet-ether extract showed maximum anti-psoriatic activity (increased orthokeratotic region by 25%) amongst the extracts tested wher ...
... chemical and spectral data. The screening for anti-psoriatic activity was carried out by topical application of different extracts and isolated compounds. The successive pet-ether extract showed maximum anti-psoriatic activity (increased orthokeratotic region by 25%) amongst the extracts tested wher ...
Aldehyde Oxidase Activity in Donor
... [1,2,4]triazolo[4,3-b]pyridazin-3-ylthio)quinoline) not identified preclinically was reported to cause acute renal toxicity as a result of extremely poor solubility and crystallization in the kidney (Diamond et al., 2010). Unfortunately, all these aforementioned examples of early clinical failures c ...
... [1,2,4]triazolo[4,3-b]pyridazin-3-ylthio)quinoline) not identified preclinically was reported to cause acute renal toxicity as a result of extremely poor solubility and crystallization in the kidney (Diamond et al., 2010). Unfortunately, all these aforementioned examples of early clinical failures c ...
Characterization of the Analgesic and Anti
... (R)-ketorolac, INDO, and DS were highly correlated with their anti-inflammatory potencies, suggesting a common mechanism. (R,S)-ketorolac was significantly more potent than INDO or DS in vivo. Neither difference in relative potency of COX inhibition for (R,S)-ketorolac over INDO and DS nor activity ...
... (R)-ketorolac, INDO, and DS were highly correlated with their anti-inflammatory potencies, suggesting a common mechanism. (R,S)-ketorolac was significantly more potent than INDO or DS in vivo. Neither difference in relative potency of COX inhibition for (R,S)-ketorolac over INDO and DS nor activity ...
Dissolution Stability of Cephalexin Extemporaneous Suspensions
... effective pharmaceutical formulations for patients hypersensitive to penicillin and for patients who have difficulty swallowing solid dosage forms. Cephalosporins are active pharmaceutical ingredients used worldwide in oral formulations because of their proven track record of broad-spectrum antibact ...
... effective pharmaceutical formulations for patients hypersensitive to penicillin and for patients who have difficulty swallowing solid dosage forms. Cephalosporins are active pharmaceutical ingredients used worldwide in oral formulations because of their proven track record of broad-spectrum antibact ...
Different FRP Resin Chemistries for Different Chemical Environments
... resins. Note that these resins have only two ester groups per molecule (highlighted below). This is significant in that ester groups can be susceptible to chemical attack. Fewer ester groups generally translates to better chemical resistance. The Bisphenol A epoxy group, shown in the brackets, impar ...
... resins. Note that these resins have only two ester groups per molecule (highlighted below). This is significant in that ester groups can be susceptible to chemical attack. Fewer ester groups generally translates to better chemical resistance. The Bisphenol A epoxy group, shown in the brackets, impar ...
Off-label antibiotic use in children in three European countries
... patients or would provide a significant benefit over existing treatments [24]. The European Medicines Agency (EMEA) has laid down specific rules for marketing authorisations of new medicinal products and for pediatric-use marketing authorisations of off-patent products [25]. It has also agreed a str ...
... patients or would provide a significant benefit over existing treatments [24]. The European Medicines Agency (EMEA) has laid down specific rules for marketing authorisations of new medicinal products and for pediatric-use marketing authorisations of off-patent products [25]. It has also agreed a str ...
Review on Prodrugs
... to release the active parent drug, which can then elicit its desired pharmacological effect in the body. In most cases, prodrugs are simple chemical derivatives that are only one or two chemical or enzymatic steps away from the active parent drug. However, some prodrugs lack an obvious carrier or pr ...
... to release the active parent drug, which can then elicit its desired pharmacological effect in the body. In most cases, prodrugs are simple chemical derivatives that are only one or two chemical or enzymatic steps away from the active parent drug. However, some prodrugs lack an obvious carrier or pr ...
Anthelmintic activity of Pyrostegia venusta using Pheretima posthuma
... Approximately 3 million people are infected with helminthes worldwide. Helminthes infections are commonly found in villages of developing countries and are being recognized as cause of much acute as well as chronic illness among the human beings as well as cattle’s. Hence, the treatment for helminti ...
... Approximately 3 million people are infected with helminthes worldwide. Helminthes infections are commonly found in villages of developing countries and are being recognized as cause of much acute as well as chronic illness among the human beings as well as cattle’s. Hence, the treatment for helminti ...
Discovery and development of cephalosporins
Cephalosporins are a broad class of bactericidal antibiotics that include the β-lactam ring and share a structural similarity and mechanism of action with other β-lactam antibiotics (e.g. penicillins, carbapenems and monobactams). The cephalosporins (and other β-lactams) have the ability to kill bacteria by inhibiting essential steps in the bacterial cell wall synthesis which in the end results in osmotic lysis and death of the bacterial cell. Cephalosporins are widely used antibiotics because of their clinical efficiency and desirable safety profile.The cephalosporins are diverse in their antibacterial spectrum, water solubility, acid tolerability, oral bioavailability, biological half-life and other properties. Therefore the cephalosporins can be further classified into generations depending on antibacterial activity, time of invention and structural basis.