Regarding Janssen-Cilag`s application to get Concerta approved for
... The stories about diversion and abuse tell about a scene already out of control. Full use of the Swedish Prescribed Drug Register for the years 2005-2010 would present data verifying the stories from the “users”. Instead of providing “all available retrospective data” in this area, using for example ...
... The stories about diversion and abuse tell about a scene already out of control. Full use of the Swedish Prescribed Drug Register for the years 2005-2010 would present data verifying the stories from the “users”. Instead of providing “all available retrospective data” in this area, using for example ...
Placebo effects: clinical aspects and neurobiology
... or the purported inert control condition not being inert (Kienle and Kiene, 1997; Ader, 2000; Miller et al., 2004). The natural history is particularly problematic, since it is impossible to infer anything about the frequency or size of placebo effects without a control for the placebo condition. Un ...
... or the purported inert control condition not being inert (Kienle and Kiene, 1997; Ader, 2000; Miller et al., 2004). The natural history is particularly problematic, since it is impossible to infer anything about the frequency or size of placebo effects without a control for the placebo condition. Un ...
Tuberculosis_1
... C. For early tuberculosis revealing among children D. For early tuberculosis revealing among adults E. For revealing the persons with the increased risk of tuberculosis illness ANSWER C 38. A 6 years old boy K., had a “range” of tuberculin reaction. What examinations should be done? A. General clini ...
... C. For early tuberculosis revealing among children D. For early tuberculosis revealing among adults E. For revealing the persons with the increased risk of tuberculosis illness ANSWER C 38. A 6 years old boy K., had a “range” of tuberculin reaction. What examinations should be done? A. General clini ...
Tdap Vaccination Strategies for Adolescents and Adults, Including
... example, pertussis, or whooping cough, a highly contagious disease that can be prevented with a vaccine. An infectious disease of the upper respiratory tract characterized by coughing spasms (or paroxysms) and often followed by an inspiratory “whoop” or vomiting,2 pertussis is the most common vaccin ...
... example, pertussis, or whooping cough, a highly contagious disease that can be prevented with a vaccine. An infectious disease of the upper respiratory tract characterized by coughing spasms (or paroxysms) and often followed by an inspiratory “whoop” or vomiting,2 pertussis is the most common vaccin ...
Transdermal Nicotine Maintenance Attenuates the
... and cocaine. Each participant was exposed to two chronic drug maintenance phases (21 mg/day nicotine transdermal patch and placebo transdermal patch). Within each drug phase, the participant received intravenous injections of placebo, cocaine (15 and 30 mg/70 kg), caffeine (200 and 400 mg/70 kg), an ...
... and cocaine. Each participant was exposed to two chronic drug maintenance phases (21 mg/day nicotine transdermal patch and placebo transdermal patch). Within each drug phase, the participant received intravenous injections of placebo, cocaine (15 and 30 mg/70 kg), caffeine (200 and 400 mg/70 kg), an ...
Journal of Obstetrics and Gynaecology Canada
... uncontrolled experiments (such as the results of treatment with penicillin in the 1940s) could also be included in this ...
... uncontrolled experiments (such as the results of treatment with penicillin in the 1940s) could also be included in this ...
The Powerful Placebo Effect: Fact or Fiction?
... treatment, or they were excluded from evaluation until they felt better again. In a study on angina pectoris [3], patients got placebos as long as they only had a few episodes of angina; when the episodes increased, they received one of the test drugs. Thus good periods were selected for placebo tre ...
... treatment, or they were excluded from evaluation until they felt better again. In a study on angina pectoris [3], patients got placebos as long as they only had a few episodes of angina; when the episodes increased, they received one of the test drugs. Thus good periods were selected for placebo tre ...
Maternal, Perinatal and Infant Mortality in South Australia
... 1. There were three maternal deaths in 2013: one direct maternal death, one indirect maternal death and one incidental maternal death. The maternal mortality ratio for the last eight-year period 2006-2013 was 8.3 deaths per 100,000 women who gave birth, which is low by international standards. It w ...
... 1. There were three maternal deaths in 2013: one direct maternal death, one indirect maternal death and one incidental maternal death. The maternal mortality ratio for the last eight-year period 2006-2013 was 8.3 deaths per 100,000 women who gave birth, which is low by international standards. It w ...
Review on Mycobacterium Tuberculosis
... BCG (Bacillus of Calmette and Guerin) is the commonly available vaccine for tuberculosis till date [114-117]. It consists of live attenuated strains being derived from Mycobacterium bovis which were supposed to be among the avirulent strains for about 60 years [38]. The vaccine was developed in 1921 ...
... BCG (Bacillus of Calmette and Guerin) is the commonly available vaccine for tuberculosis till date [114-117]. It consists of live attenuated strains being derived from Mycobacterium bovis which were supposed to be among the avirulent strains for about 60 years [38]. The vaccine was developed in 1921 ...
ACIP Recommendations on Influenza Vaccination
... most influential. For example, population-based estimates of influenza disease burden supported by laboratory-confirmed influenza virus infection outcomes contribute the most specific data. The best evidence for vaccine or antiviral efficacy comes from randomized controlled trials that assess labora ...
... most influential. For example, population-based estimates of influenza disease burden supported by laboratory-confirmed influenza virus infection outcomes contribute the most specific data. The best evidence for vaccine or antiviral efficacy comes from randomized controlled trials that assess labora ...
A Literature Review on the Status and Effects of Salvia Divinorum on
... Salvia divinorum is one of more than 700 members of the plant genus “salvia,” and is considered a member of the sage and mint family (Valdes & Seymour, 1998). Salvia divinorum was primarily used by the Mazatec Indian culture of Oaxaca, Mexico for medicinal and spiritual purposes (Wasson, 1962). Medi ...
... Salvia divinorum is one of more than 700 members of the plant genus “salvia,” and is considered a member of the sage and mint family (Valdes & Seymour, 1998). Salvia divinorum was primarily used by the Mazatec Indian culture of Oaxaca, Mexico for medicinal and spiritual purposes (Wasson, 1962). Medi ...
Chapter 5
... These elastic vesicles were able to penetrate pores much smaller than their diameter [16]. Recently, it was suggested that these elastic vesicles may act as carrier systems; after non-occlusive application elastic vesicles and bound fluorescent label followed the same route of penetration into the s ...
... These elastic vesicles were able to penetrate pores much smaller than their diameter [16]. Recently, it was suggested that these elastic vesicles may act as carrier systems; after non-occlusive application elastic vesicles and bound fluorescent label followed the same route of penetration into the s ...
Placebo interventions, placebo effects and clinical practice
... data also indicate that the actual frequency is rare, because pure placebos are usually applied only once or a few times to a small minority of patients. There are three basic motivational patterns for such intentional use of a pure placebo. First, the physician aims primarily to promote the patient ...
... data also indicate that the actual frequency is rare, because pure placebos are usually applied only once or a few times to a small minority of patients. There are three basic motivational patterns for such intentional use of a pure placebo. First, the physician aims primarily to promote the patient ...
Biomedical Side Effects of Doping
... Since the Olympic Games in Munich in 1972, the fight against doping has become a task of the Federal Institute of Sport Science (BISp). Following the Olympics in 1972, the Federal Institute of Sport Science took over the promotion of doping analysis which was conducted by the then young lecturer Dr. ...
... Since the Olympic Games in Munich in 1972, the fight against doping has become a task of the Federal Institute of Sport Science (BISp). Following the Olympics in 1972, the Federal Institute of Sport Science took over the promotion of doping analysis which was conducted by the then young lecturer Dr. ...
Hepatitis B Training for Patient Navigators/Health
... becomes infected with hepatitis B a doctor may advise that a specific treatment isn’t needed. Many people are infected when they are very young and they or their parents may not even be aware that they have the infection. But it’s especially important to identify those who are infected at this early ...
... becomes infected with hepatitis B a doctor may advise that a specific treatment isn’t needed. Many people are infected when they are very young and they or their parents may not even be aware that they have the infection. But it’s especially important to identify those who are infected at this early ...
The Vaccine Adverse Event Reporting System (VAERS) Results Form
... At 2 months of age, 8/27/97, HIB #1, Hep B #1, IVP #2, DTaP #1; 10/22/97 HIB #2, Hep B #2, IPV #2, DTaP #2. Reacted to immunization with fever then several hours later convulsions. Seizures not present prior. No improvement over several weeks. Took child to hospital and doctor gave 10/27/97 shots; I ...
... At 2 months of age, 8/27/97, HIB #1, Hep B #1, IVP #2, DTaP #1; 10/22/97 HIB #2, Hep B #2, IPV #2, DTaP #2. Reacted to immunization with fever then several hours later convulsions. Seizures not present prior. No improvement over several weeks. Took child to hospital and doctor gave 10/27/97 shots; I ...
Draft Guide A: Smallpox Surveillance and Case Reporting; Contact Identification,
... Suspect case: A case with a febrile rash illness with fever preceding development of rash by 1-4 days. D. Clinical types of variola major As described by Fenner in his classic textbook “Smallpox and its Eradication” (www.who.int/emc/diseases/smallpox/smallpoxeradication.html), it has long been recog ...
... Suspect case: A case with a febrile rash illness with fever preceding development of rash by 1-4 days. D. Clinical types of variola major As described by Fenner in his classic textbook “Smallpox and its Eradication” (www.who.int/emc/diseases/smallpox/smallpoxeradication.html), it has long been recog ...
Core Data Sheet
... 4.2 Posology and method of administration ............................................................................. 3 4.3 Contraindications ................................................................................................................ 3 4.4 Special warnings and special precauti ...
... 4.2 Posology and method of administration ............................................................................. 3 4.3 Contraindications ................................................................................................................ 3 4.4 Special warnings and special precauti ...
Evaluation of 22 SIN List 2.0 substances according to
... Substances are placed in category 1 when they are known to have produced ED adverse effects in humans or animal species living in the environment or when there is evidence from animal studies, possibly supplemented with other information, to provide a strong presumption that the substance has the ca ...
... Substances are placed in category 1 when they are known to have produced ED adverse effects in humans or animal species living in the environment or when there is evidence from animal studies, possibly supplemented with other information, to provide a strong presumption that the substance has the ca ...
Evaluation of 22 SIN List 2.0 substances according to the Danish
... Substances are placed in category 1 when they are known to have produced ED adverse effects in humans or animal species living in the environment or when there is evidence from animal studies, possibly supplemented with other information, to provide a strong presumption that the substance has the ca ...
... Substances are placed in category 1 when they are known to have produced ED adverse effects in humans or animal species living in the environment or when there is evidence from animal studies, possibly supplemented with other information, to provide a strong presumption that the substance has the ca ...
Allergic rhinitis and School Performance
... in which nasal corticoid therapy reduced congestion and improved sleep [5]. Since then, several studies have attempted to determine whether allergic rhinitis intrinsically exerts a negative effect upon patient cognitive function and quality of life, independently of the negative side effects of trea ...
... in which nasal corticoid therapy reduced congestion and improved sleep [5]. Since then, several studies have attempted to determine whether allergic rhinitis intrinsically exerts a negative effect upon patient cognitive function and quality of life, independently of the negative side effects of trea ...
Prevention and control of outbreaks of seasonal
... rapidly with the proportion of people aged 65 and older forecast to increase from 14% in 2010 to 25% in 2050. The WHO Regional Office for Europe, through the European health policy framework Health 2020, aims to significantly improve the health and well-being of populations, reduce health inequaliti ...
... rapidly with the proportion of people aged 65 and older forecast to increase from 14% in 2010 to 25% in 2050. The WHO Regional Office for Europe, through the European health policy framework Health 2020, aims to significantly improve the health and well-being of populations, reduce health inequaliti ...
Evidence-based Management of Postoperative Ileus
... motility is usually the limiting factor in resolving POI.4,9 An examination of GI recovery in patients who underwent bowel resection in 3 clinical trials found that most patients tolerated solid food and had a bowel movement by postoperative day 4, with the majority of patients discharged from the h ...
... motility is usually the limiting factor in resolving POI.4,9 An examination of GI recovery in patients who underwent bowel resection in 3 clinical trials found that most patients tolerated solid food and had a bowel movement by postoperative day 4, with the majority of patients discharged from the h ...
Which neuroreceptors mediate the subjective effects of MDMA in
... three different neuroreceptor pretreatments on the subjective, cardiovascular and adverse effects of MDMA (1.5 mg/kg orally) in 44 healthy human volunteers. Pretreatments were: the selective serotonin reuptake inhibitor citalopram (40 mg intravenously) in 16 subjects, the 5-HT2 antagonist ketanserin ...
... three different neuroreceptor pretreatments on the subjective, cardiovascular and adverse effects of MDMA (1.5 mg/kg orally) in 44 healthy human volunteers. Pretreatments were: the selective serotonin reuptake inhibitor citalopram (40 mg intravenously) in 16 subjects, the 5-HT2 antagonist ketanserin ...
Prevention and Control of Influenza Recommendations of the Advisory Committee
... aged 50–64 years, because this group has an elevated prevalence of certain chronic medical conditions; and 3) persons who live with or care for persons at high risk (e.g., health-care workers and household members who have frequent contact with persons at high risk and can transmit influenza to pers ...
... aged 50–64 years, because this group has an elevated prevalence of certain chronic medical conditions; and 3) persons who live with or care for persons at high risk (e.g., health-care workers and household members who have frequent contact with persons at high risk and can transmit influenza to pers ...
Non-specific effect of vaccines
Non-specific effects of vaccines (also called “heterologous effects"" or ""off-target effects"") are effects which go beyond the specific protective effects against the targeted diseases. Non-specific effects can be strongly beneficial, increasing protection against non-targeted infections, but also at times negative, increasing susceptibility to non-targeted infections. This depends on both the vaccine and the sex of the infant.All live attenuated vaccines studied so far (BCG vaccine, measles vaccine, oral polio vaccine, smallpox vaccine) have been shown to reduce mortality more than can be explained by prevention of the targeted infections. In contrast, inactivated vaccines (diphtheria-tetanus-pertussis vaccine (DTP), hepatitis B vaccine, inactivated polio vaccine) may increase overall mortality despite providing protection against the target diseases.These effects may be long-lasting, at least up to the time point where a new type of vaccine is given. The non-specific effects can be very pronounced, with significant effects on overall mortality and morbidity. In a situation with herd immunity to the target disease, the non-specific effects can be more important for overall health than the specific vaccine effects.The non-specific effects should not be confused with the side effects of vaccines (such as local reactions at the side of vaccination or general reactions such as fever, head ache or rash, which usually resolve within days to weeks - or in rare cases anaphylaxis). Rather, non-specific effects represent a form of general immunomodulation, with important consequences for the immune system’s ability to handle subsequent challenges.It is estimated that millions of child deaths in low income countries could be prevented every year if the non-specific effects of vaccines were taken into consideration in immunization programs.