Independent effects of preload, afterload, and contractility on left
... to occur between the time of aortic valve closure and mitral valve opening, when cavity volume is fixed (10, 11, 23), and systolic torsion has been demonstrated in isolated isovolumic beating hearts (20). Thus under some circumstances, torsion may vary with force, as well as with volume. Because ino ...
... to occur between the time of aortic valve closure and mitral valve opening, when cavity volume is fixed (10, 11, 23), and systolic torsion has been demonstrated in isolated isovolumic beating hearts (20). Thus under some circumstances, torsion may vary with force, as well as with volume. Because ino ...
Chapter 14 Paroxysmal Supraventricular Tachycardias and the
... syndrome. Electrocardiographic studies of healthy individuals suggest that the incidence of this condition is 3 in 1000 of the general population.12 Early studies suggested that the morbidity and mortality in WPW syndrome with tachyarrhythmias were greater in adults with ventricular fibrillation occ ...
... syndrome. Electrocardiographic studies of healthy individuals suggest that the incidence of this condition is 3 in 1000 of the general population.12 Early studies suggested that the morbidity and mortality in WPW syndrome with tachyarrhythmias were greater in adults with ventricular fibrillation occ ...
33rd ADVANCED ECHO CONFERENCE
... rare diseases will be discussed with illustrative patient examples. Participants will also receive a comprehensive review of the current state-of-theart applications of echocardiography in valvular heart disease. ...
... rare diseases will be discussed with illustrative patient examples. Participants will also receive a comprehensive review of the current state-of-theart applications of echocardiography in valvular heart disease. ...
Left Ventricular Septal and Left Ventricular Apical Pacing
... contractility, relaxation, and myocardial efficiency (stroke work/myocardial oxygen consumption). In contrast, LV apical and LV septal pacing did not significantly alter these parameters as compared with the values during intrinsic conduction. At 16 weeks, acute intrasubject comparison showed that s ...
... contractility, relaxation, and myocardial efficiency (stroke work/myocardial oxygen consumption). In contrast, LV apical and LV septal pacing did not significantly alter these parameters as compared with the values during intrinsic conduction. At 16 weeks, acute intrasubject comparison showed that s ...
Action Potential Dynamics Explain Arrhythmic Vulnerability in
... restitution (20) as best-fit straight lines for flat AT restitution (arbitrarily, absolute slope ⬍0.2), and for lengthening AT (conduction slowing) at short DI. We report DI where AT begins to lengthen (4). Computational modeling. To study mechanisms explaining AP and TWA, a human LV transmural wedg ...
... restitution (20) as best-fit straight lines for flat AT restitution (arbitrarily, absolute slope ⬍0.2), and for lengthening AT (conduction slowing) at short DI. We report DI where AT begins to lengthen (4). Computational modeling. To study mechanisms explaining AP and TWA, a human LV transmural wedg ...
Between Right and Left Coronary Artery in Man
... the right coronary artery), transient ischemic STsegment depression of 1 mm or more had been demonstrated during ischemic attacks when they entered the emergency room. In the remaining 10 patients ischemic ECG changes were observed in the exercise stress test. No patient had ST-segment elevation dur ...
... the right coronary artery), transient ischemic STsegment depression of 1 mm or more had been demonstrated during ischemic attacks when they entered the emergency room. In the remaining 10 patients ischemic ECG changes were observed in the exercise stress test. No patient had ST-segment elevation dur ...
Effects and mechanisms of curcumin on the
... 4. Discussion There are several studies about therapeutic effects of curcumin (6,18); however there are only a few studies about the dose–response relationship of the effects of curcumin (13). The adverse effects and dose–response relationship of the effects of curcumin when it is used as a drug nee ...
... 4. Discussion There are several studies about therapeutic effects of curcumin (6,18); however there are only a few studies about the dose–response relationship of the effects of curcumin (13). The adverse effects and dose–response relationship of the effects of curcumin when it is used as a drug nee ...
Development of Heart Failure and Congenital Septal
... examined by light microscopy. To quantify the incidence of septal defects, neonatal hearts (36 eNOS⫺/⫺, 34 eNOS⫹/⫺ , and 41 eNOS⫹/⫹) were fixed in 10% buffered formalin, and a standard procedure for microdissection of the heart was applied according to methods described previously.18,19 Briefly, the ...
... examined by light microscopy. To quantify the incidence of septal defects, neonatal hearts (36 eNOS⫺/⫺, 34 eNOS⫹/⫺ , and 41 eNOS⫹/⫹) were fixed in 10% buffered formalin, and a standard procedure for microdissection of the heart was applied according to methods described previously.18,19 Briefly, the ...
and the role of cardiac resynchronization therapy
... ventricular pacing have shown that asynchronous ventricular activation immediately deteriorates left ventricular (LV) function.7 Moreover, evidence is increasing that asynchronous ventricular activation is associated with structural changes in the long run. Animal studies have shown that long-term L ...
... ventricular pacing have shown that asynchronous ventricular activation immediately deteriorates left ventricular (LV) function.7 Moreover, evidence is increasing that asynchronous ventricular activation is associated with structural changes in the long run. Animal studies have shown that long-term L ...
Prevalence and Consequence of Systolic Hypertension in Children
... such as stroke, myocardial infarction, and congestive heart failure are rare except in cases of severe hypertension. In the absence of these events, the most extensively investigated surrogate marker of hypertensive morbidity in children has been the geometry and size of the left ventricle measured ...
... such as stroke, myocardial infarction, and congestive heart failure are rare except in cases of severe hypertension. In the absence of these events, the most extensively investigated surrogate marker of hypertensive morbidity in children has been the geometry and size of the left ventricle measured ...
EARLY POSTNATAL CARDIAC DEVELOPMENT IN ATRIAL NATRIURETIC PEPTIDE GENE-DISRUPTED MICE
... Figure 10. Methodological images of polymer injection ............................................................... 41 Figure 11. Effect of proANP gene-disruption on heart weight to body weight ratios. .................. 45 Figure 12. Effect of proANP gene-disruption on hematocrit. ............... ...
... Figure 10. Methodological images of polymer injection ............................................................... 41 Figure 11. Effect of proANP gene-disruption on heart weight to body weight ratios. .................. 45 Figure 12. Effect of proANP gene-disruption on hematocrit. ............... ...
View Presentation - Society of Thoracic Radiology
... limiting potential acute AV regurgitation, 7) coordinate, in the short term, right and left ventricular stroke volumes when there is elevated peripheral vascular resistance (e.g. elevated systemic blood pressure). Embryology The embryology of the pericardium is important in understanding the common ...
... limiting potential acute AV regurgitation, 7) coordinate, in the short term, right and left ventricular stroke volumes when there is elevated peripheral vascular resistance (e.g. elevated systemic blood pressure). Embryology The embryology of the pericardium is important in understanding the common ...
EHRA/HRS Expert Consensus on Catheter Ablation of
... Haemodynamically unstable VT causes haemodynamic compromise requiring prompt termination. Idiopathic VT is a term that has been used to indicate VT that is known to occur in the absence of clinically apparent structural heart disease. Idioventricular rhythm is three or more consecutive beats at a ra ...
... Haemodynamically unstable VT causes haemodynamic compromise requiring prompt termination. Idiopathic VT is a term that has been used to indicate VT that is known to occur in the absence of clinically apparent structural heart disease. Idioventricular rhythm is three or more consecutive beats at a ra ...
Clinical predictors of the defibrillation threshold with the
... threshold and patient age, history of heart surgery, history of myocardial infarction, history of ventricular tachycardia, recent amiodarone therapy, cardiothoracic ratio, the distance between the two electrodes on the posteroanterior chest roentgenogram, posterior and septal wall thickness on echoc ...
... threshold and patient age, history of heart surgery, history of myocardial infarction, history of ventricular tachycardia, recent amiodarone therapy, cardiothoracic ratio, the distance between the two electrodes on the posteroanterior chest roentgenogram, posterior and septal wall thickness on echoc ...
Pacing Therapies for Heart Failure (PDF Available)
... functions of these devices, covering the indications for their use and common problems encountered with this technology, in a logical, evidence-based manner. We have also taken a “how-to-do-it” approach for certain areas of implantable device function. The inclusion of these sections will be of inte ...
... functions of these devices, covering the indications for their use and common problems encountered with this technology, in a logical, evidence-based manner. We have also taken a “how-to-do-it” approach for certain areas of implantable device function. The inclusion of these sections will be of inte ...
Crawford Current Cardiology Edition 2
... 2. Dyspnea—A frequent complaint of patients with a variety of cardiac diseases, dyspnea is ordinarily one of four types. The most common is exertional dyspnea, which usually means that the underlying condition is mild because it requires the increased demand of exertion to precipitate symptoms. The ...
... 2. Dyspnea—A frequent complaint of patients with a variety of cardiac diseases, dyspnea is ordinarily one of four types. The most common is exertional dyspnea, which usually means that the underlying condition is mild because it requires the increased demand of exertion to precipitate symptoms. The ...
The University of Birmingham Na+/Ca2+ exchange and Na+/K+
... mechanism is elusive. One hypothesis is that the binding of Na+ to its transport site drives the exchanger into an inactivated state (Hilgemann et al. 1992). However, mutagenesis studies have shown that a region within the large cytoplasmic loop is also involved in this process (Matsuoka et al. 1995 ...
... mechanism is elusive. One hypothesis is that the binding of Na+ to its transport site drives the exchanger into an inactivated state (Hilgemann et al. 1992). However, mutagenesis studies have shown that a region within the large cytoplasmic loop is also involved in this process (Matsuoka et al. 1995 ...
The Only EKG Book You`ll Ever Need, 5th Edition
... On the opposi te page i s a normal el ectrocardiogram, or EKG. By the ti me you have fi ni shed thi s book—and i t won't take very much ti me at al l —you wil l be abl e to recogni ze a normal EKG al most i nstantl y. Perhaps even more i mportantl y, you wi ll have learned to spot all of the common ...
... On the opposi te page i s a normal el ectrocardiogram, or EKG. By the ti me you have fi ni shed thi s book—and i t won't take very much ti me at al l —you wil l be abl e to recogni ze a normal EKG al most i nstantl y. Perhaps even more i mportantl y, you wi ll have learned to spot all of the common ...
Modelling of the ventricular conduction system
... delay in the passage of the electrical wave from the atria to the ventricles, ensuring that the ventricles contract after the atria. In the ventricles the excitation spreads at a high speed from the AV node through the Hisbundle, left and right Tawara branches and Purkinje fibres. The Purkinje fibres ...
... delay in the passage of the electrical wave from the atria to the ventricles, ensuring that the ventricles contract after the atria. In the ventricles the excitation spreads at a high speed from the AV node through the Hisbundle, left and right Tawara branches and Purkinje fibres. The Purkinje fibres ...
ECG TUTORIAL for Clinicians
... The usual transition from S>R in the right precordial leads to R>S in the left precordial leads is V3 or V4. Small "septal" q-waves may be seen in leads V5 and V6. ST Segment: In a sense, the term "ST segment" is a misnomer, because a discrete ST segment distinct from the T wave is often not seen. ...
... The usual transition from S>R in the right precordial leads to R>S in the left precordial leads is V3 or V4. Small "septal" q-waves may be seen in leads V5 and V6. ST Segment: In a sense, the term "ST segment" is a misnomer, because a discrete ST segment distinct from the T wave is often not seen. ...
070199 Prevalence and Clinical Outcome of Mitral
... ITRAL-VALVE prolapse has been described as a common disorder, with prevalence estimates generally ranging from 5 to 15 percent and up to 35 percent in some studies.1-7 In addition, mitral-valve prolapse has often been portrayed as a disease with frequent and serious complications, including stroke, ...
... ITRAL-VALVE prolapse has been described as a common disorder, with prevalence estimates generally ranging from 5 to 15 percent and up to 35 percent in some studies.1-7 In addition, mitral-valve prolapse has often been portrayed as a disease with frequent and serious complications, including stroke, ...
impact of isoprenaline and caffeine on development of left
... as an increase in mass and size of the left ventricle which frequently occurs as a result of an elevated resistance within the circulatory system. This increase in mass of the myocardium results from a chronically raised workload on the heart (1) and is taken as an early sign of cardiomyopathy, whic ...
... as an increase in mass and size of the left ventricle which frequently occurs as a result of an elevated resistance within the circulatory system. This increase in mass of the myocardium results from a chronically raised workload on the heart (1) and is taken as an early sign of cardiomyopathy, whic ...
The Mammalian Ste20-like Kinase 2 (Mst2) Modulates Stress
... (Fig. 1A). Because inhibition of Hippo pathway in embryonic hearts resulted in increased cardiomyocyte proliferation (8), we therefore analyzed cardiomyocyte proliferation in Mst2⫺/⫺ neonatal hearts. We examined hearts from 3-day-old WT and Mst2⫺/⫺ neonates and stained them with markers of cell mito ...
... (Fig. 1A). Because inhibition of Hippo pathway in embryonic hearts resulted in increased cardiomyocyte proliferation (8), we therefore analyzed cardiomyocyte proliferation in Mst2⫺/⫺ neonatal hearts. We examined hearts from 3-day-old WT and Mst2⫺/⫺ neonates and stained them with markers of cell mito ...
Pericardial Cyst : A Rare Cause of Pericardial Effusion
... masses in contact with the heart. Transthoracic echocardiography is helpful in showing the exact location of the cyst and in differentiating a cyst from other entities, such as a fat pad, aneurysm, or solid tumour 5. On CT and MRI, a pericardial cyst typically appears as a non-enhanced, oval, well-d ...
... masses in contact with the heart. Transthoracic echocardiography is helpful in showing the exact location of the cyst and in differentiating a cyst from other entities, such as a fat pad, aneurysm, or solid tumour 5. On CT and MRI, a pericardial cyst typically appears as a non-enhanced, oval, well-d ...
Catheter Ablation of Supraventricular and Ventricular Arrhythmias
... recording relative to the delta wave onset may also indicate an optimal ablation site.18 The atrial insertion of an accessory pathway is usually localized by identifying the site of the shortest ventriculoatrial (VA) interval during ventricular pacing or during circus movement tachycardia or by reco ...
... recording relative to the delta wave onset may also indicate an optimal ablation site.18 The atrial insertion of an accessory pathway is usually localized by identifying the site of the shortest ventriculoatrial (VA) interval during ventricular pacing or during circus movement tachycardia or by reco ...
Hypertrophic cardiomyopathy
Hypertrophic cardiomyopathy (HCM) is a primary disease of the myocardium (the muscle of the heart) in which a portion of the myocardium is hypertrophied (thickened) without any obvious cause, creating functional impairment of the cardiac muscle. It is a leading cause of sudden cardiac death in young athletes.The occurrence of hypertrophic cardiomyopathy is a significant cause of sudden unexpected cardiac death in any age group and as a cause of disabling cardiac symptoms. Younger people are likely to have a more severe form of hypertrophic cardiomyopathy.HCM is frequently asymptomatic until sudden cardiac death, and for this reason some suggest routinely screening certain populations for this disease.A cardiomyopathy is a disease that affects the muscle of the heart. With HCM, the myocytes (cardiac contractile cells) in the heart increase in size, which results in the thickening of the heart muscle. In addition, the normal alignment of muscle cells is disrupted, a phenomenon known as myocardial disarray. HCM also causes disruptions of the electrical functions of the heart. HCM is most commonly due to a mutation in one of nine sarcomeric genes that results in a mutated protein in the sarcomere, the primary component of the myocyte (the muscle cell of the heart). These are predominantly single-point missense mutations in the genes for beta-myosin heavy chain (MHC), myosin-binding protein C, cardiac troponinT, or tropomyosin. These mutations cause myofibril and myocyte structural abnormalities and possible deficiencies in force generation. Not to be confused with dilated cardiomyopathy or any other cardiomyopathy.While most literature so far focuses on European, American, and Japanese populations, HCM appears in all ethnic groups. The prevalence of HCM is about 0.2% to 0.5% of the general population.