MacVector 14.0 Getting Started Guide
... Screening clones from a site-specific mutagenesis experiment to identify successful mutations Screening related clones for single nucleotide polymorphisms ...
... Screening clones from a site-specific mutagenesis experiment to identify successful mutations Screening related clones for single nucleotide polymorphisms ...
Consistent risk group-associated differences in human
... more than one of the trees, but none was present in all (except the related viruses mentioned above). Bootstrap values in the analyses based on individual genes were generally low. This instability was reflected in an analysis based on all three genes together, which yielded a tree with three stable ...
... more than one of the trees, but none was present in all (except the related viruses mentioned above). Bootstrap values in the analyses based on individual genes were generally low. This instability was reflected in an analysis based on all three genes together, which yielded a tree with three stable ...
Likelihood Based Clustering (LiBaC) for Codon Models, a method
... negatively impact estimates of substitution rates (e.g., Yang and Nielsen 2000; Dunn, Bielawski and Yang 2001; Aris-Brosou and Bielawski 2006) and classification of sites according to selection pressure (e.g., Anisimova, Bielawski and Yang 2002; Wong et al. 2004; Kosakovsky Pond and Muse, 2005). Reg ...
... negatively impact estimates of substitution rates (e.g., Yang and Nielsen 2000; Dunn, Bielawski and Yang 2001; Aris-Brosou and Bielawski 2006) and classification of sites according to selection pressure (e.g., Anisimova, Bielawski and Yang 2002; Wong et al. 2004; Kosakovsky Pond and Muse, 2005). Reg ...
No Slide Title
... Why Nasonia’s relationships still need studying • Nasonia is a model system for evolutionary biology studies, yet… • Ancestral states cannot be inferred with only three analyzed species! • No agreement in classification of wasps in its family (Pteromalidae) • Needed: means to reject some pteromalid ...
... Why Nasonia’s relationships still need studying • Nasonia is a model system for evolutionary biology studies, yet… • Ancestral states cannot be inferred with only three analyzed species! • No agreement in classification of wasps in its family (Pteromalidae) • Needed: means to reject some pteromalid ...
Geneious Sequence Classifier User Manual
... database sequences. There is a trade-off between how fast the search runs versus how sensitive it is to finding distantly related matches. A higher sensitivity will align queries that are more distantly related to the database, so if you suspect your query sequence may be only distantly related to y ...
... database sequences. There is a trade-off between how fast the search runs versus how sensitive it is to finding distantly related matches. A higher sensitivity will align queries that are more distantly related to the database, so if you suspect your query sequence may be only distantly related to y ...
Sequence comparison of aflR from different Aspergillus species
... 1994; Hesseltine et al., 1970), the SBG strain of A. flavus (Cotty and Cardwell, 1999), or A. flavus Group II (Geiser et al., 2000; Geiser et al., 1998). A. nomius isolates were chosen which show considerable morphological, physiological, and genetic divergence. Ex type cultures of A. nomius (Kurtzman ...
... 1994; Hesseltine et al., 1970), the SBG strain of A. flavus (Cotty and Cardwell, 1999), or A. flavus Group II (Geiser et al., 2000; Geiser et al., 1998). A. nomius isolates were chosen which show considerable morphological, physiological, and genetic divergence. Ex type cultures of A. nomius (Kurtzman ...
Hybrid Cloud and Cluster Computing
... • MDS and GTM are highly memory and time consuming process for large dataset such as millions of data points • MDS requires O(N2) and GTM does O(KN) (N is the number of data points and K is the number of latent variables) • Training only for sampled data and interpolating for out-ofsample set can im ...
... • MDS and GTM are highly memory and time consuming process for large dataset such as millions of data points • MDS requires O(N2) and GTM does O(KN) (N is the number of data points and K is the number of latent variables) • Training only for sampled data and interpolating for out-ofsample set can im ...
Runge-Kutta Methods
... does not meet the user prescribed tolerance If this is the case, the step size should be decrased, yn is rejected and it’s to be computed again… ...
... does not meet the user prescribed tolerance If this is the case, the step size should be decrased, yn is rejected and it’s to be computed again… ...
Multi-objective optimization methods in drug design
... proposed. The method optimizes two objectives, namely the correlation of docking scores to biological activity and the averaged root mean squared deviation with respect to a defined co-crystallized inhibitor. The set of equivalent QSAR models produced are subsequently clustered and a representative ...
... proposed. The method optimizes two objectives, namely the correlation of docking scores to biological activity and the averaged root mean squared deviation with respect to a defined co-crystallized inhibitor. The set of equivalent QSAR models produced are subsequently clustered and a representative ...
Models of Selection, Isolation, and Gene Flow in Speciation
... dN/dS. If the rate of accumulation of synonymous substitution differences among sequences is mainly attributed to the accumulation of new mutations over time, and if those substitutions are largely invisible to selection on protein function, then a higher (or lower) rate of accumulation of nonsynony ...
... dN/dS. If the rate of accumulation of synonymous substitution differences among sequences is mainly attributed to the accumulation of new mutations over time, and if those substitutions are largely invisible to selection on protein function, then a higher (or lower) rate of accumulation of nonsynony ...
DOCX
... Additions – O(n) Multiplications by powers of two (actually left-shifts) – O(n) Four n/2-bit multiplications – xLyL, xLyR, xRyL, xRyR – with recursive calls. Our method for multiplying n-bit numbers starts by making recursive calls to multiply these four pairs of n/2-bit numbers (four sub-prob ...
... Additions – O(n) Multiplications by powers of two (actually left-shifts) – O(n) Four n/2-bit multiplications – xLyL, xLyR, xRyL, xRyR – with recursive calls. Our method for multiplying n-bit numbers starts by making recursive calls to multiply these four pairs of n/2-bit numbers (four sub-prob ...
Expressed Sequence Tag (EST)
... EST clustering consists in incorporating overlapping ESTs which tag the same Transcript of the same gene in a single cluster For clustering, we measure the similarity (distance) between any 2 sequences. The distance is then reduced to a simple binary value: - accept or reject two sequences in the sa ...
... EST clustering consists in incorporating overlapping ESTs which tag the same Transcript of the same gene in a single cluster For clustering, we measure the similarity (distance) between any 2 sequences. The distance is then reduced to a simple binary value: - accept or reject two sequences in the sa ...
Maximum likelihood methods for detecting adaptive evolution after
... this reason, adaptive evolution will be very difficult to detect in gene families by using a pairwise approach to estimating d N/d S ratios. We need tools to (1) estimate selective pressures at different time points in the phylogenetic history of a gene, and (2) test the hypothesis that those estima ...
... this reason, adaptive evolution will be very difficult to detect in gene families by using a pairwise approach to estimating d N/d S ratios. We need tools to (1) estimate selective pressures at different time points in the phylogenetic history of a gene, and (2) test the hypothesis that those estima ...