Multifractal characterisation of length sequences of coding and
... results, as they all look into only a certain aspect of the entire DNA sequence [12]. The avoided and under-represented strings in some bacterial complete genomes have been discussed [13–15]. A time series model of CDS in complete genome has been proposed [16]. Vieira [17] performed a low-frequency ...
... results, as they all look into only a certain aspect of the entire DNA sequence [12]. The avoided and under-represented strings in some bacterial complete genomes have been discussed [13–15]. A time series model of CDS in complete genome has been proposed [16]. Vieira [17] performed a low-frequency ...
... Recently, a new type of hybrid resulting from the hybridization between Saccharomyces cerevisiae and Saccharomyces kudriavzevii was described. These strains exhibit physiological properties of potential biotechnological interest. A preliminary characterization of these hybrids showed a trend to redu ...
D. melanogaster - GEP Community Server
... D. biarmipes Muller F element TSS annotation projects Reconcile coding region annotations submitted by ...
... D. biarmipes Muller F element TSS annotation projects Reconcile coding region annotations submitted by ...
The rapidly evolving field of plant centromeres
... region into the heterochromatin [15,16], and a tract of 5S rDNA was inserted into CEN3 [17]. Whether such changes generally characterize the evolution of plant centromeres remains to be determined, but their occurrence on three of the five Arabidopsis centromeres warrants further analysis. Furthermo ...
... region into the heterochromatin [15,16], and a tract of 5S rDNA was inserted into CEN3 [17]. Whether such changes generally characterize the evolution of plant centromeres remains to be determined, but their occurrence on three of the five Arabidopsis centromeres warrants further analysis. Furthermo ...
genomebiology.com
... introns that contain TEs in invertebrates D. melanogaster and C. elegans is 1.7% and 5.6%, respectively. These results indicate that only a very small portion of introns in invertebrates contain TEs (2 to 5%) compared to 20 to 40% of introns in non-mammalian vertebrates and approximately 60% in mamm ...
... introns that contain TEs in invertebrates D. melanogaster and C. elegans is 1.7% and 5.6%, respectively. These results indicate that only a very small portion of introns in invertebrates contain TEs (2 to 5%) compared to 20 to 40% of introns in non-mammalian vertebrates and approximately 60% in mamm ...
- eScholarship@UMMS - University of Massachusetts
... fibroblast cell lines were used in this study: an HGPS patient fibroblast (HGPS), a normal cell line from the father of the HGPS patient (Father), and an age-matched normal fibroblast line (Age Control). Two biological replicates were performed at different passages, since some changes in HGPS may p ...
... fibroblast cell lines were used in this study: an HGPS patient fibroblast (HGPS), a normal cell line from the father of the HGPS patient (Father), and an age-matched normal fibroblast line (Age Control). Two biological replicates were performed at different passages, since some changes in HGPS may p ...
Correlation of amino acid preference and
... Three types of analysis are conducted. At the genome level, crossvalidation is used to demonstrate the predictive capability of amino acid preference of viral genome type. Next at the sequence level, two types of resampling analysis are used to investigate the correlation of amino acid preference an ...
... Three types of analysis are conducted. At the genome level, crossvalidation is used to demonstrate the predictive capability of amino acid preference of viral genome type. Next at the sequence level, two types of resampling analysis are used to investigate the correlation of amino acid preference an ...
Alu repeat analysis in the complete human genome: trends and
... Alu elements (Korenberg and Rykowski, 1988; Moyzis et al., 1989). Initial analysis of the first draft of human genome also revealed their association with gene and GC regions of the genome (Lander et al., 2001). It has also been reported that these elements are unevenly distributed and there is a po ...
... Alu elements (Korenberg and Rykowski, 1988; Moyzis et al., 1989). Initial analysis of the first draft of human genome also revealed their association with gene and GC regions of the genome (Lander et al., 2001). It has also been reported that these elements are unevenly distributed and there is a po ...
Gene regulation in three dimensions
... Last, but not least I would like to thank Julie my fiancé who has supported me and been there for me when I needed it the most. K.T.W ...
... Last, but not least I would like to thank Julie my fiancé who has supported me and been there for me when I needed it the most. K.T.W ...
An accessible database for mouse and human whole transcriptome
... We carried out an automatic primer design procedure to target all possible transcripts and all ‘possible’ exon–exon and intron– exon junctions in the human and mouse transcriptomes. Not all consecutive exon–intron–exon triplets generate ‘possible’ primer pairs (i.e. satisfy the constraints). The res ...
... We carried out an automatic primer design procedure to target all possible transcripts and all ‘possible’ exon–exon and intron– exon junctions in the human and mouse transcriptomes. Not all consecutive exon–intron–exon triplets generate ‘possible’ primer pairs (i.e. satisfy the constraints). The res ...
Applications of Bioinformatics and Genomics/Proteomics
... Summary: In this final course of the BPG program, students will be familiarized with the most advanced computational techniques, programs and databases used at the frontiers of biomedical sciences. Advanced applications will be covered in four broad areas: new bioinformatics tools, genomics, proteom ...
... Summary: In this final course of the BPG program, students will be familiarized with the most advanced computational techniques, programs and databases used at the frontiers of biomedical sciences. Advanced applications will be covered in four broad areas: new bioinformatics tools, genomics, proteom ...
Genome organization of Magnaporthe grisea
... considerable efforts have been made to understand the genetics and molecular biology of this fungus. Three different genetic maps for this organism have been reported (Romao and Hamer 1992; Skinner et al. 1993; Sweigard et al. 1993). One map, containing 98 RFLP markers, two isoenzymes and the mating ...
... considerable efforts have been made to understand the genetics and molecular biology of this fungus. Three different genetic maps for this organism have been reported (Romao and Hamer 1992; Skinner et al. 1993; Sweigard et al. 1993). One map, containing 98 RFLP markers, two isoenzymes and the mating ...
Specialized adaptation of a lactic acid bacterium to the milk
... (10.6%) in the LMD-9 strain that are not present in CNRZ1066 and LMG 18311, respectively. These genomic segments correspond mainly to 73 and 65 regions of >50 bp specific in LMD-9 when compared to CNRZ1066 and LMG 18311 genomes, respectively. Collectively, an approximate 114 kb of LMD-9 chromosomal ...
... (10.6%) in the LMD-9 strain that are not present in CNRZ1066 and LMG 18311, respectively. These genomic segments correspond mainly to 73 and 65 regions of >50 bp specific in LMD-9 when compared to CNRZ1066 and LMG 18311 genomes, respectively. Collectively, an approximate 114 kb of LMD-9 chromosomal ...
PowerPoint-presentatie - the biopsychology research group
... processes underlying disease vulnerability, variable gene expression, has been estimated at 18% (1). The involvement of CNVs in ADHD etiology has not been investigated. Within the International Multisite ADHD Genetics (IMAGE) study, sponsored by the Genetic Association Information Network (GAIN), a ...
... processes underlying disease vulnerability, variable gene expression, has been estimated at 18% (1). The involvement of CNVs in ADHD etiology has not been investigated. Within the International Multisite ADHD Genetics (IMAGE) study, sponsored by the Genetic Association Information Network (GAIN), a ...
Nucleic Acids Research, 32: D489-D492 (2004).
... expressed in the liver. Examination of the isoform sequence CK2a¢, revealed a translated Alu-containing cassette exon incorporated into the mature mRNA. This C-terminal sequence was found to be essential in the determination of the nuclear localization of the CK2a¢¢ isoform (10). Alus were also foun ...
... expressed in the liver. Examination of the isoform sequence CK2a¢, revealed a translated Alu-containing cassette exon incorporated into the mature mRNA. This C-terminal sequence was found to be essential in the determination of the nuclear localization of the CK2a¢¢ isoform (10). Alus were also foun ...
The Rat Gene Map
... and others 1993). The first comprehensive linkage map based on a single F 2 interstrain cross was published in 1995 (Jacob and others 1995); additional large linkage maps based on recombinant inbred strains (Pravenec and others 1996) or on other interstrain crosses (Bihoreau and others 1997) were re ...
... and others 1993). The first comprehensive linkage map based on a single F 2 interstrain cross was published in 1995 (Jacob and others 1995); additional large linkage maps based on recombinant inbred strains (Pravenec and others 1996) or on other interstrain crosses (Bihoreau and others 1997) were re ...
Fifteen years of genomewide scans for selection: trends, lessons
... refine our understanding of a variety of evolutionary processes including convergent evolution. The use of genomewide data, which, unlike candidate gene approaches, interrogates variation across the genome, is meant to identify selective targets unbiased by a priori expectations (Ellegren 2014). Yet ...
... refine our understanding of a variety of evolutionary processes including convergent evolution. The use of genomewide data, which, unlike candidate gene approaches, interrogates variation across the genome, is meant to identify selective targets unbiased by a priori expectations (Ellegren 2014). Yet ...
human genome research
... Completion of this project will represent a remarkable achievement, especially considering that the first DNA sequencing methods were not developed until the 1970s. Such detailed knowledge of the human genome will open up new areas of research in basic biology, biomedicine, biotechnology and health ...
... Completion of this project will represent a remarkable achievement, especially considering that the first DNA sequencing methods were not developed until the 1970s. Such detailed knowledge of the human genome will open up new areas of research in basic biology, biomedicine, biotechnology and health ...
Exome sequencing as a tool for Mendelian disease gene discovery
... publically available control exomes should increase the popularity of this approach. A major challenge of relating rare variants to a trait is that even with very large sample sizes, the power to detect an association with a single rare variant is low. To address this issue, analysis strategies have ...
... publically available control exomes should increase the popularity of this approach. A major challenge of relating rare variants to a trait is that even with very large sample sizes, the power to detect an association with a single rare variant is low. To address this issue, analysis strategies have ...
High-resolution haplotype structure in the human genome
... relevant variation, for population genetics, and for the next steps of the Human Genome Project. Focusing on haplotype blocks greatly clarifies LD analyses. Once the haplotype blocks are identified, they can be treated as alleles and tested for LD (for example, our simple analysis uses Hedrick’s mul ...
... relevant variation, for population genetics, and for the next steps of the Human Genome Project. Focusing on haplotype blocks greatly clarifies LD analyses. Once the haplotype blocks are identified, they can be treated as alleles and tested for LD (for example, our simple analysis uses Hedrick’s mul ...
Horizontal transfer of non-LTR retrotransposons: artifact or rare event
... 2008). For example, HT of CR1B elements was identified along with the analysis of non-LTR retrotransposons diversity in Maculinea genomes. Bioinformatic approaches can greatly expand opportunities to observe the distribution and evolutionary history of non-LTR retrotransposons in various eukaryotic ...
... 2008). For example, HT of CR1B elements was identified along with the analysis of non-LTR retrotransposons diversity in Maculinea genomes. Bioinformatic approaches can greatly expand opportunities to observe the distribution and evolutionary history of non-LTR retrotransposons in various eukaryotic ...
Tutorial - QIAGEN Bioinformatics
... Click the "Run..." button to start the workflow wizard. It will ask you to provide the inputs, such as the reference sequence, control reads, and sample reads. It will also offer you to inspect and/or change (depending on lock settings) configurable parameters. Finally, it will offer you to save res ...
... Click the "Run..." button to start the workflow wizard. It will ask you to provide the inputs, such as the reference sequence, control reads, and sample reads. It will also offer you to inspect and/or change (depending on lock settings) configurable parameters. Finally, it will offer you to save res ...
Lesson Overview - mr. welling` s school page
... For example, humans have three genes responsible for color vision, all located on the X chromosome. In males, a defective allele for any of these genes results in colorblindness, an inability to distinguish certain colors. The most common form, red-green colorblindness, occurs in about 1 in 12 males ...
... For example, humans have three genes responsible for color vision, all located on the X chromosome. In males, a defective allele for any of these genes results in colorblindness, an inability to distinguish certain colors. The most common form, red-green colorblindness, occurs in about 1 in 12 males ...
Human Genome Project
The Human Genome Project (HGP) is an international scientific research project with the goal of determining the sequence of chemical base pairs which make up human DNA, and of identifying and mapping all of the genes of the human genome from both a physical and functional standpoint. It remains the world's largest collaborative biological project. The project was proposed and funded by the US government; planning started in 1984, got underway in 1990, and was declared complete in 2003. A parallel project was conducted outside of government by the Celera Corporation, or Celera Genomics, which was formally launched in 1998. Most of the government-sponsored sequencing was performed in twenty universities and research centers in the United States, the United Kingdom, Japan, France, Germany, and China.The Human Genome Project originally aimed to map the nucleotides contained in a human haploid reference genome (more than three billion). The ""genome"" of any given individual is unique; mapping ""the human genome"" involves sequencing multiple variations of each gene.