Glycogen Metabolism
... • Allosteric regulation is the regulation of an enzyme’s activity by the binding of an effector molecule at a site other than the active site. It can be positive or negative • The inactive phosphorylated form, b, of glycogen synthase is allosterically activated by glucose-6phosphate ...
... • Allosteric regulation is the regulation of an enzyme’s activity by the binding of an effector molecule at a site other than the active site. It can be positive or negative • The inactive phosphorylated form, b, of glycogen synthase is allosterically activated by glucose-6phosphate ...
Molecular and cellular requirements for the
... adenylate cyclases over the last few years – both at the biochemical and cell-biological levels. From a biochemical viewpoint it will be of considerable interest to know what makes some cyclases subject to high-affinity inhibition by Ca2+ and others insensitive, given that adenylate cyclases are at ...
... adenylate cyclases over the last few years – both at the biochemical and cell-biological levels. From a biochemical viewpoint it will be of considerable interest to know what makes some cyclases subject to high-affinity inhibition by Ca2+ and others insensitive, given that adenylate cyclases are at ...
The Amino-acid Sequence in the Phenylalanyl Chain of Insulin
... listed in Table 14. It was shown by chromatography with benzyl alcohol that isoleucine is absent. On account of the limited chromatographic apparatus available, and the labour involved, it was desirable to use one-dimensional chromatograms as far as possible to identify the amino-acids present. In t ...
... listed in Table 14. It was shown by chromatography with benzyl alcohol that isoleucine is absent. On account of the limited chromatographic apparatus available, and the labour involved, it was desirable to use one-dimensional chromatograms as far as possible to identify the amino-acids present. In t ...
Amino Acid-Protecting Groups
... peptide chemistry and is mandatory to prevent polymerization of the amino acid once it is activated. As most peptide syntheses, both in solution and on solid phase, are carried out in the C to N direction, α-amino-protecting groups (temporary protecting groups) are removed several times during the s ...
... peptide chemistry and is mandatory to prevent polymerization of the amino acid once it is activated. As most peptide syntheses, both in solution and on solid phase, are carried out in the C to N direction, α-amino-protecting groups (temporary protecting groups) are removed several times during the s ...
Vitamins and related Compounds
... exclusively by microorganisms and is found in the liver of animals bound to protein as methylcobalamin or 5'-deoxyadenosylcobalamin. The vitamin must be hydrolyzed from protein in order to be active. Hydrolysis occurs in the stomach by gastric acid or in the intestine by trypsin digestion following ...
... exclusively by microorganisms and is found in the liver of animals bound to protein as methylcobalamin or 5'-deoxyadenosylcobalamin. The vitamin must be hydrolyzed from protein in order to be active. Hydrolysis occurs in the stomach by gastric acid or in the intestine by trypsin digestion following ...
Solution Report - Delhi Academy of Medical Sciences
... A general description of postmortem changes due to decomposition basically includes two stages of autolysis, and four stages of putrefaction, besides some conservative phenomena such as saponification or adipocere, natural mummification, calcification, etc. ...
... A general description of postmortem changes due to decomposition basically includes two stages of autolysis, and four stages of putrefaction, besides some conservative phenomena such as saponification or adipocere, natural mummification, calcification, etc. ...
Nicotinamide adenine dinucleotide, a metabolic regulator of
... components of the de novo pathway reside evenly throughout the cell and have no effect on silencing [14,15]. NAD also regulates gene expression at other genomic loci. Clock/BMAL1 and NPAS2/BMAL1 are heterodimeric transcription factors that regulate the expression of genes controlling the circadian ...
... components of the de novo pathway reside evenly throughout the cell and have no effect on silencing [14,15]. NAD also regulates gene expression at other genomic loci. Clock/BMAL1 and NPAS2/BMAL1 are heterodimeric transcription factors that regulate the expression of genes controlling the circadian ...
An investigation of protective formulations containing
... the reaction is called substrate and the enzyme turns them into products. Almost all process in the human body needs enzymes so the reaction occurs at a speed that is sufficient for the body. Every ...
... the reaction is called substrate and the enzyme turns them into products. Almost all process in the human body needs enzymes so the reaction occurs at a speed that is sufficient for the body. Every ...
evidence for nonsense mutations in the arom gene
... in each of the four structural genes for which mutants are available in the arom cluster. These results are consistent with the conclusion that some non-complementing pleiotropic arom mutants are a consequence of nonsense mutations within the proximal structural gene (arom-2) of the arom gene cluste ...
... in each of the four structural genes for which mutants are available in the arom cluster. These results are consistent with the conclusion that some non-complementing pleiotropic arom mutants are a consequence of nonsense mutations within the proximal structural gene (arom-2) of the arom gene cluste ...
Suberin biosynthesis in O. sativa: characterisation of a cytochrome
... An organism is defined to be alive when it features certain characteristics: It has to have the ability to reproduce itself, a metabolism to absorb and convert energy from the environment and to build its own components, it has to be discrete from its surrounding media, and maintain its homoeostasis ...
... An organism is defined to be alive when it features certain characteristics: It has to have the ability to reproduce itself, a metabolism to absorb and convert energy from the environment and to build its own components, it has to be discrete from its surrounding media, and maintain its homoeostasis ...
GLUCOKINASE ACTIVATORS: A GLUCOSE SENSOR ROLE IN PANCREATIC ISLETS AND HEPATOCYTE
... GKAs are, small molecules with a considerable variety of chemical structures that mostly adhere to a common pharmacophore model with related structural moties. The model consists of a center of a carbon or an aromatic ring with three attachments to it. Two of these are hydrophobic, and at least one ...
... GKAs are, small molecules with a considerable variety of chemical structures that mostly adhere to a common pharmacophore model with related structural moties. The model consists of a center of a carbon or an aromatic ring with three attachments to it. Two of these are hydrophobic, and at least one ...
Targeting apicoplasts in malaria parasites
... generated from a virtual proteome assembled by combining information about the characteristic signals needed to direct nuclear-encoded proteins to the apicoplast with the function of the genes that carried those signals. The Plasmodium apicoplast was revealed as a stripped down version of a chloropl ...
... generated from a virtual proteome assembled by combining information about the characteristic signals needed to direct nuclear-encoded proteins to the apicoplast with the function of the genes that carried those signals. The Plasmodium apicoplast was revealed as a stripped down version of a chloropl ...
Noba Vital range - Noba Vital Plus, Noba Vital
... developed Noba Vital Pure on the basis of a unique, fatty acid complex formula consisting of medium-chain fatty acids (C8-C10-C12). Scientific research performed by Noba has shown that Noba Vital Plus has a positive effect on the villus/crypt ratio. This results in the growth of a vital intestinal e ...
... developed Noba Vital Pure on the basis of a unique, fatty acid complex formula consisting of medium-chain fatty acids (C8-C10-C12). Scientific research performed by Noba has shown that Noba Vital Plus has a positive effect on the villus/crypt ratio. This results in the growth of a vital intestinal e ...
Investigating the Role of ADP-forming Acetyl-CoA
... variety of organisms. When the incoming carbon flux surpasses the capacity of central metabolic pathways, excess acetyl-CoA will undergo fermentation and recycle CoA. An additional benefit of acetate fermentation is the generation of energy-containing compounds such as ATP. The production of acetate ...
... variety of organisms. When the incoming carbon flux surpasses the capacity of central metabolic pathways, excess acetyl-CoA will undergo fermentation and recycle CoA. An additional benefit of acetate fermentation is the generation of energy-containing compounds such as ATP. The production of acetate ...
Structure-based design of inhibitors of NS3 serine protease
... C-terminal region (residues 94–175) contains a six-stranded -barrel that ends with a helix. The active site (His:57, Asp:81 and Ser:139) is located between these two regions and is formed by a shallow solvent exposed pocket requiring many interaction points for binding of substrates or inhibitors [ ...
... C-terminal region (residues 94–175) contains a six-stranded -barrel that ends with a helix. The active site (His:57, Asp:81 and Ser:139) is located between these two regions and is formed by a shallow solvent exposed pocket requiring many interaction points for binding of substrates or inhibitors [ ...
20 Insulin Secretion and Action
... metabolism is diabetes mellitus although other derangements are significant but not often encountered. Of all the humoral and neuronal regulatory mechanisms for glucose metabolism, insulin is the hormone that lowers serum glucose whereas most other mechanisms function to increase serum glucose. Insu ...
... metabolism is diabetes mellitus although other derangements are significant but not often encountered. Of all the humoral and neuronal regulatory mechanisms for glucose metabolism, insulin is the hormone that lowers serum glucose whereas most other mechanisms function to increase serum glucose. Insu ...
Nucleotide sequence of the Tn10 encoded tetracycline resistance
... of a second hairpin structure in the transcript ahead of the terminator. The stem and loop sizes are quite similar to those found in attenuators [17], however, the possibility to form an alternative structure necessary for attenuation is not found [17]. It is not clear whether this feature of the se ...
... of a second hairpin structure in the transcript ahead of the terminator. The stem and loop sizes are quite similar to those found in attenuators [17], however, the possibility to form an alternative structure necessary for attenuation is not found [17]. It is not clear whether this feature of the se ...
Autotrophic CO2 fixation via the reductive tricarboxylic acid cycle in
... metabolites. While most of the enzymes are shared between the reductive and oxidative TCA cycle, three enzymes are essential to run this cycle in reverse: 2-oxoglutarate : ferredoxin oxidoreductase, fumarate reductase and ATP citrate lyase. The latter enzyme catalyses the ATP- and the CoA-dependent ...
... metabolites. While most of the enzymes are shared between the reductive and oxidative TCA cycle, three enzymes are essential to run this cycle in reverse: 2-oxoglutarate : ferredoxin oxidoreductase, fumarate reductase and ATP citrate lyase. The latter enzyme catalyses the ATP- and the CoA-dependent ...
SODIUM-COUPLED TRANSPORTERS FOR KREBS CYCLE
... Krebs cycle intermediates such as succinate, citrate, and α-ketoglutarate are transferred across plasma membranes of cells by secondary active transporters that couple the downhill movement of sodium to the concentrative uptake of substrate. Several transporters have been identified in isolated memb ...
... Krebs cycle intermediates such as succinate, citrate, and α-ketoglutarate are transferred across plasma membranes of cells by secondary active transporters that couple the downhill movement of sodium to the concentrative uptake of substrate. Several transporters have been identified in isolated memb ...
MEDICAL GRAND ROUNDS PARKLAND
... cells are "set" not to secrete . Just as nutrients are required to turn beta cells on , nutrients are required to turn alpha cells off . If one blocks glucose metabolism in a dog by infusing 2 - deoxy - glucose , a non-metabolizable glucose analog which s tops the Emden-Meyerhoff pathway at 2-deoxyg ...
... cells are "set" not to secrete . Just as nutrients are required to turn beta cells on , nutrients are required to turn alpha cells off . If one blocks glucose metabolism in a dog by infusing 2 - deoxy - glucose , a non-metabolizable glucose analog which s tops the Emden-Meyerhoff pathway at 2-deoxyg ...
Antimicrobial peptides
... HoWever, very feW of these molecules are suggested for intended use in aquaculture, e.g. penaeidins isolated from ...
... HoWever, very feW of these molecules are suggested for intended use in aquaculture, e.g. penaeidins isolated from ...