Curriculum Vitae - Laureate Institute for Brain Research
... I am a Professor in Residence in the Department of Psychiatry at the University of California San Diego (UCSD) and the Director of Telemental Health at the Veterans Affairs San Diego Health Care System (VASDHS). My research focuses on the interface between interoception, i.e. the processing of senso ...
... I am a Professor in Residence in the Department of Psychiatry at the University of California San Diego (UCSD) and the Director of Telemental Health at the Veterans Affairs San Diego Health Care System (VASDHS). My research focuses on the interface between interoception, i.e. the processing of senso ...
Rationalizing Context-Dependent Preferences: Divisive
... This research was funded by the Army Research Office (W911ND-11-1-0482), and the experiment was approved by an IRB. The authors wish to thank A. Caplin, N.G. Martineau and T. LoFaro for helpful comments, as well as seminar participants at Harvard University, the University of Zurich, and Maastricht ...
... This research was funded by the Army Research Office (W911ND-11-1-0482), and the experiment was approved by an IRB. The authors wish to thank A. Caplin, N.G. Martineau and T. LoFaro for helpful comments, as well as seminar participants at Harvard University, the University of Zurich, and Maastricht ...
The ventral striatum - Brain imaging of Parkinson`s disease
... The role of ventral striatum in the processes of reward, motivation, and decision-making is now generally accepted based on a broad range of results coming from neuroimaging studies in humans and from local pharmacological disturbances studies in animals, mostly rats. In the rat, it was shown that t ...
... The role of ventral striatum in the processes of reward, motivation, and decision-making is now generally accepted based on a broad range of results coming from neuroimaging studies in humans and from local pharmacological disturbances studies in animals, mostly rats. In the rat, it was shown that t ...
“left or right” Decision-making beyond
... cortex depends on whether the choice is indicated by a hand or an eye movement, in an otherwise identical sensory discrimination task (Cui and Andersen, 2007). On the other hand, a recent fMRI study on humans (Heekeren et al., 2006) revealed a candidate brain region for abstract representation of p ...
... cortex depends on whether the choice is indicated by a hand or an eye movement, in an otherwise identical sensory discrimination task (Cui and Andersen, 2007). On the other hand, a recent fMRI study on humans (Heekeren et al., 2006) revealed a candidate brain region for abstract representation of p ...
Neurodynamical theory of decision confidence Andrea Insabato TESI DOCTORAL UPF / 2014
... that a double-layer attractor neural network can account for neural recordings and behavior of rats in a post-decision wagering experiment. In this model a decision-making layer takes the perceptual decision and a separate confidence layer monitors the activity of the decisionmaking layer and makes ...
... that a double-layer attractor neural network can account for neural recordings and behavior of rats in a post-decision wagering experiment. In this model a decision-making layer takes the perceptual decision and a separate confidence layer monitors the activity of the decisionmaking layer and makes ...
The precision of value-based choices depends causally on
... by the other, choice-irrelevant type of evidence (Supplementary Table 1). Moreover, inspection of the data at the subject-level and non-parametric statistical analyses revealed that the effects of tACS were present in the vast majority of the subjects and were not due to the influence of outliers (Su ...
... by the other, choice-irrelevant type of evidence (Supplementary Table 1). Moreover, inspection of the data at the subject-level and non-parametric statistical analyses revealed that the effects of tACS were present in the vast majority of the subjects and were not due to the influence of outliers (Su ...
Expected Value, Reward Outcome, and
... Figure 2. Task performance. (a) The choices of a subject in the decision task. The solid line shows the EV on the right in 3 different sets of 30 trials. Right and Left responses are shown. Each subject was run with a random order of the different EV trial sets. (b) The percentage of choices to the ...
... Figure 2. Task performance. (a) The choices of a subject in the decision task. The solid line shows the EV on the right in 3 different sets of 30 trials. Right and Left responses are shown. Each subject was run with a random order of the different EV trial sets. (b) The percentage of choices to the ...
Development of emotional facial recognition in late
... of DSM-IV Axis I mental disorders. An abbreviated version of the Wechsler Intelligence Scale for Children (WISC-R) provided an estimate of intelligence for the children and adolescents (Wechsler, 1974). The Wechsler Adult Intelligence Scale (WAIS-III) was used to evaluate intelligence in adults (Wec ...
... of DSM-IV Axis I mental disorders. An abbreviated version of the Wechsler Intelligence Scale for Children (WISC-R) provided an estimate of intelligence for the children and adolescents (Wechsler, 1974). The Wechsler Adult Intelligence Scale (WAIS-III) was used to evaluate intelligence in adults (Wec ...
Neural coding of basic reward terms of animal
... the reinforcer [7]. Uncertainty is different from probability; it is highest at probability (p)¼0.5 and decreases toward lower and higher probabilities, where reward absence or presence becomes increasingly certain. Uncertainty can be assessed as entropy, variance, and the associability term of atte ...
... the reinforcer [7]. Uncertainty is different from probability; it is highest at probability (p)¼0.5 and decreases toward lower and higher probabilities, where reward absence or presence becomes increasingly certain. Uncertainty can be assessed as entropy, variance, and the associability term of atte ...
Prefrontal cortex damage abolishes brand-cued
... and we do not have any a priori hypothesis about the laterality of brain areas important for brand preference, we include both unilateral and bilateral VMPC lesions in our target group. The chemical senses (smell, taste) can be affected by VMPC damage, so it was important to rule out a basic confoun ...
... and we do not have any a priori hypothesis about the laterality of brain areas important for brand preference, we include both unilateral and bilateral VMPC lesions in our target group. The chemical senses (smell, taste) can be affected by VMPC damage, so it was important to rule out a basic confoun ...
Neural correlates of incidental and directed facial emotion
... A developmental milestone for social communication and interactions is the ability to regulate one’s own emotional reactions in order to produce socially appropriate behaviors (Adolphs, 2002; Bell and Deater-Deckard, 2007). There is some consensus on the view that better emotional selfregulation in ...
... A developmental milestone for social communication and interactions is the ability to regulate one’s own emotional reactions in order to produce socially appropriate behaviors (Adolphs, 2002; Bell and Deater-Deckard, 2007). There is some consensus on the view that better emotional selfregulation in ...
decision-making in the primate brain
... paired with two novel stimuli (X and Y), and, in this second stage of the experiment, the joint stimuli AX and BY are both paired with rewards. If learning were merely associative, the subject would respond to both novel stimuli X and Y as if they predicted the reward. In fact, under these condition ...
... paired with two novel stimuli (X and Y), and, in this second stage of the experiment, the joint stimuli AX and BY are both paired with rewards. If learning were merely associative, the subject would respond to both novel stimuli X and Y as if they predicted the reward. In fact, under these condition ...
Synaptic Plasticity and Connectivity Requirements to
... the sign of plasticity from the relative times of each single presynaptic and single postsynaptic spike pair but fails to replicate such rate dependence. The higher order spike interactions included in triplet STDP fit recent in vitro data better [16,17,18,19], as well as the observed rate dependenc ...
... the sign of plasticity from the relative times of each single presynaptic and single postsynaptic spike pair but fails to replicate such rate dependence. The higher order spike interactions included in triplet STDP fit recent in vitro data better [16,17,18,19], as well as the observed rate dependenc ...
Emotion Dysregulation
... Adolescence is a fascinating developmental period because of the remarkable changes that occur. The social, biological, and psychological worlds of children develop dramatically during adolescence, evoking a variety of emotions. For example, adolescents may experience joy with their newfound autonom ...
... Adolescence is a fascinating developmental period because of the remarkable changes that occur. The social, biological, and psychological worlds of children develop dramatically during adolescence, evoking a variety of emotions. For example, adolescents may experience joy with their newfound autonom ...
Empathic choice involves vmPFC value signals that are modulated
... performed a similar task, except that now they made purchase decisions for themselves out of a $10 cash endowment that belonged to them. A randomly selected trial was again chosen, and the associated decision implemented at the conclusion of the two sessions. At the end of the second session, subjec ...
... performed a similar task, except that now they made purchase decisions for themselves out of a $10 cash endowment that belonged to them. A randomly selected trial was again chosen, and the associated decision implemented at the conclusion of the two sessions. At the end of the second session, subjec ...
When Is an Adolescent an Adult? - Waisman Laboratory for Brain
... All analyses were performed on the data from the 110 subjects with usable imaging and behavioral data. We examined responses to the debriefing questions and the SCR data to assess the efficacy of our emotionalstate manipulation. A 1-Hz filter was applied to the raw SCR data. Data were smoothed for e ...
... All analyses were performed on the data from the 110 subjects with usable imaging and behavioral data. We examined responses to the debriefing questions and the SCR data to assess the efficacy of our emotionalstate manipulation. A 1-Hz filter was applied to the raw SCR data. Data were smoothed for e ...
What Are Emotional States, and Why Do We
... noxious stimuli. 4. Communication. Monkeys, for example, may communicate their emotional state to others, for instance by making face expressions (such as an open-mouth threat to indicate the extent to which they are willing to compete for resources), and this may influence the behaviour of other a ...
... noxious stimuli. 4. Communication. Monkeys, for example, may communicate their emotional state to others, for instance by making face expressions (such as an open-mouth threat to indicate the extent to which they are willing to compete for resources), and this may influence the behaviour of other a ...
Investigating the neurocognitive deficits associated with chronic
... deficits on free-recall and list-learning tasks, and difficulties on both selective and divided attention tasks. Solowij et al. [16], using a design involving very wellmatched groups of light and heavy users, have provided evidence that heavy, chronic use of cannabis may be associated with relativel ...
... deficits on free-recall and list-learning tasks, and difficulties on both selective and divided attention tasks. Solowij et al. [16], using a design involving very wellmatched groups of light and heavy users, have provided evidence that heavy, chronic use of cannabis may be associated with relativel ...
Adaptive neural coding: from biological to behavioral decision
... parietal cortex underlying action selection and execution. In these areas, single neurons represent specific actions, allowing observation of alternative-specific neural activity. For example, in the monkey lateral intraparietal area (LIP), individual neurons fire selectively to both visual stimulus ...
... parietal cortex underlying action selection and execution. In these areas, single neurons represent specific actions, allowing observation of alternative-specific neural activity. For example, in the monkey lateral intraparietal area (LIP), individual neurons fire selectively to both visual stimulus ...
The Role of Ventromedial Prefrontal Cortex in Decision Making
... to choose between stimuli, presented 2 at a time. Three categories of stimuli were used: food, famous people, and colors. Eight names of food (e.g., pizza slice, carrot sticks), 6 photographs of people (e.g., Britney Spears, Shaquille O’Neal), and 6 color swatches (e.g., pink, yellow) were printed o ...
... to choose between stimuli, presented 2 at a time. Three categories of stimuli were used: food, famous people, and colors. Eight names of food (e.g., pizza slice, carrot sticks), 6 photographs of people (e.g., Britney Spears, Shaquille O’Neal), and 6 color swatches (e.g., pink, yellow) were printed o ...
Neural Mechanisms of Bias and Sensitivity in Hiroshi Nishida Muneyoshi Takahashi
... reaction time during decision making. An important merit of reaction-time analysis is that it increases the statistical power, especially when considering neural activity on a trial-by-trial basis. The Linear Approach to Threshold with Ergodic Rate model (LATER model) is one model for the analysis o ...
... reaction time during decision making. An important merit of reaction-time analysis is that it increases the statistical power, especially when considering neural activity on a trial-by-trial basis. The Linear Approach to Threshold with Ergodic Rate model (LATER model) is one model for the analysis o ...
Middle Childhood and Adolescence Final Paper
... pubertal development we have to understand what is occurring during this time in the adolescent’s brain. During our childhood we are growing more and more brain cells. The brain cells contain a nucleus, axon and dendrites. The dendrites receive information, and the axons carry the information away. ...
... pubertal development we have to understand what is occurring during this time in the adolescent’s brain. During our childhood we are growing more and more brain cells. The brain cells contain a nucleus, axon and dendrites. The dendrites receive information, and the axons carry the information away. ...
Lorazepam dose-dependently decreases risk-taking
... risk-taking behavior with gains and losses, respectively, were used to evaluate the neural systems response to the experienced outcome: (1) selecting a risky response (40 or 80), which resulted in reward; and (2) selecting a risky response, which resulted in punishment (−40 or −80). These regressors ...
... risk-taking behavior with gains and losses, respectively, were used to evaluate the neural systems response to the experienced outcome: (1) selecting a risky response (40 or 80), which resulted in reward; and (2) selecting a risky response, which resulted in punishment (−40 or −80). These regressors ...
The Dual Track theory of Moral Decision-Making: A
... ing this would be of dubious help to their theory as “what is at stake here is whether all moral judgment, not all action, has an have noted, brain areas are pluripotent: that is, they ...
... ing this would be of dubious help to their theory as “what is at stake here is whether all moral judgment, not all action, has an have noted, brain areas are pluripotent: that is, they ...
Decision-making
This article deals with decision-making as analyzed in psychology. See also Decision theory.In psychology, decision-making is regarded as the cognitive process resulting in the selection of a belief or a course of action among several alternative possibilities. Every decision-making process produces a final choice that may or may not prompt action. Decision-making is the process of identifying and choosing alternatives based on the values and preferences of the decision-maker.