An Evidence-Based Approach To Cocaine-Associated Emergencies January 2008
... seizures as well as for the sense of euphoria, reinforcement, and addiction.23 The effects of cocaine on serotonergic mediated processes are unclear. Serotonin acts on CNS sites that are attributed several psychological effects such as mood, appetite, personality, affect, motor function, sexual acti ...
... seizures as well as for the sense of euphoria, reinforcement, and addiction.23 The effects of cocaine on serotonergic mediated processes are unclear. Serotonin acts on CNS sites that are attributed several psychological effects such as mood, appetite, personality, affect, motor function, sexual acti ...
Evaluation and Management of the Patient Who Has Cocaine-associated Chest Pain ,
... Platelet activation and thrombus formation also occur secondary to cocaine. Cocaine activates platelets directly [23] and indirectly through an alpha-adrenergic–mediated increase in platelet aggregability [24]. Adenosine diphosphate–induced platelet aggregation is enhanced [25], and tissue plasminog ...
... Platelet activation and thrombus formation also occur secondary to cocaine. Cocaine activates platelets directly [23] and indirectly through an alpha-adrenergic–mediated increase in platelet aggregability [24]. Adenosine diphosphate–induced platelet aggregation is enhanced [25], and tissue plasminog ...
The Management of Cocaine Associated Myocardial Ischemia
... infarction have atherosclerotic coronary artery disease.8,25 Epicardial26 and intramyocardial coronary artery disease27 has been found in cocaine users with chest pain but without myocardial infarction. The ability of cocaine to increase myocardial oxygen demand while decreasing coronary blood flow t ...
... infarction have atherosclerotic coronary artery disease.8,25 Epicardial26 and intramyocardial coronary artery disease27 has been found in cocaine users with chest pain but without myocardial infarction. The ability of cocaine to increase myocardial oxygen demand while decreasing coronary blood flow t ...
Lack of association of recreational cocaine and alcohol use
... within 30 days of their third CARDIA examination, stratification for this use pattern was not done because of small numbers in the race-gender groups. Cocaine use could not be further separated from use of other illicit drugs because only two participants admitted exclusive use of cocaine. The small ...
... within 30 days of their third CARDIA examination, stratification for this use pattern was not done because of small numbers in the race-gender groups. Cocaine use could not be further separated from use of other illicit drugs because only two participants admitted exclusive use of cocaine. The small ...
... sis.34'35 Interestingly, atherosclerotic lesions in cocaine abusers with acute coronary thrombosis did not dem¬ onstrate plaque rupture or hemorrhage suggesting that the pathophysiology of acute myocardial infarction is different from that in noncocaine users. Augmented release of vasoactive mediato ...
Recurrent ventricular arrhythmias and myocardial infarctions
... admission which was responsible for recurrent cardiovascular events. We should underline that detox programs should be the mainstay of management for cocaine addicts. ICD implantation should be considered only for a select group of patients who have cardiomyopathy and low ejection fraction related t ...
... admission which was responsible for recurrent cardiovascular events. We should underline that detox programs should be the mainstay of management for cocaine addicts. ICD implantation should be considered only for a select group of patients who have cardiomyopathy and low ejection fraction related t ...
Dangers of Cocaine
... group of drugs called ‘stimulants’, cocaine speeds up the activity of the brain and nervous system. In Australia, it is mostly available as a white powder. It can be inhaled, injected or snorted.1 Another form of cocaine is ‘crack’ cocaine which is sold as small crystals or ‘rocks’, although rarely ...
... group of drugs called ‘stimulants’, cocaine speeds up the activity of the brain and nervous system. In Australia, it is mostly available as a white powder. It can be inhaled, injected or snorted.1 Another form of cocaine is ‘crack’ cocaine which is sold as small crystals or ‘rocks’, although rarely ...
The Controversy Over Cocaine Use and Beta
... States.1 Approximately 24 million people in the United States have used cocaine at least once, and five million abuse cocaine on a regular basis.2 Its use is associated with acute and chronic complications affecting many organ systems, the most common being the cardiovascular system.3 ...
... States.1 Approximately 24 million people in the United States have used cocaine at least once, and five million abuse cocaine on a regular basis.2 Its use is associated with acute and chronic complications affecting many organ systems, the most common being the cardiovascular system.3 ...
a high-priced way of getting high -
... paranoia restlessness anxiety Signs of using cocaine include: ...
... paranoia restlessness anxiety Signs of using cocaine include: ...
Cardiovascular Complications of Cocaine Abuse
... (11%); the rest received labetalol, atenolol, or propranolol. There were no meaningful differences in EKG changes, troponin levels, length of stay, use of vasopressor agents, intubation, ventricular tachycardia/ventricular fibrillation, or death between those who did and did not receive a B-blocker. ...
... (11%); the rest received labetalol, atenolol, or propranolol. There were no meaningful differences in EKG changes, troponin levels, length of stay, use of vasopressor agents, intubation, ventricular tachycardia/ventricular fibrillation, or death between those who did and did not receive a B-blocker. ...
Cocaine and the Heart - Advocate Health Care
... sodium bicarb (baking soda) to make ‘crack’; -heat stable so can be smoked ...
... sodium bicarb (baking soda) to make ‘crack’; -heat stable so can be smoked ...
Cocaine
... People who wish to stop using cocaine should be aware that withdrawal may occur, but that it does not always need to be medically-supervised. However, physicians, detox facilities, and addiction treatment programs can help with withdrawal. Cocaine addiction can be treated in a residential setting (o ...
... People who wish to stop using cocaine should be aware that withdrawal may occur, but that it does not always need to be medically-supervised. However, physicians, detox facilities, and addiction treatment programs can help with withdrawal. Cocaine addiction can be treated in a residential setting (o ...
Cocaine - Powell County Schools
... Myocarditis, or heart muscle damage leading to heart failure Endocarditis, or inflammation of the heart lining Vascular thrombosis, or clots in the coronary arteries Pulmonary edema, or fluid in the lungs Dilated cardiomyopathy, or enlarged heart ...
... Myocarditis, or heart muscle damage leading to heart failure Endocarditis, or inflammation of the heart lining Vascular thrombosis, or clots in the coronary arteries Pulmonary edema, or fluid in the lungs Dilated cardiomyopathy, or enlarged heart ...
Cocaine
... Cocaine is abused by three commonly routes of administration, which is snorting, injecting, and smoking. ...
... Cocaine is abused by three commonly routes of administration, which is snorting, injecting, and smoking. ...
Accelerated Ventricular Rhythm and Cocaine Abuse
... A s a local anesthetic, cocaine is associated with a greater frequency of cardiac arrhythmias c o m p a r e d with other agents used during laryngoscopy (2). T h e potentiation o f catecholamine effect by cocaine was suggested in 1910 and then in 1961 by Trendelenburg (3), w h o d e m onstrated that ...
... A s a local anesthetic, cocaine is associated with a greater frequency of cardiac arrhythmias c o m p a r e d with other agents used during laryngoscopy (2). T h e potentiation o f catecholamine effect by cocaine was suggested in 1910 and then in 1961 by Trendelenburg (3), w h o d e m onstrated that ...
Health Cocaine Lesson
... 1900’s: The U.S. Government reported as many as 5,000 cocaine related deaths each year. ...
... 1900’s: The U.S. Government reported as many as 5,000 cocaine related deaths each year. ...
Fast Facts About Stimulant Drugs
... cur from as little as 1/50th of a gram. Overdose reactions include cardiac arrest, respiratory depression, and seizures. ...
... cur from as little as 1/50th of a gram. Overdose reactions include cardiac arrest, respiratory depression, and seizures. ...
Psychoactive Plants
... dopamine results in a build up of dopamine in the synapse which contributes to the high - later dopamine is depleted Blocks reuptake of norepinephrine ...
... dopamine results in a build up of dopamine in the synapse which contributes to the high - later dopamine is depleted Blocks reuptake of norepinephrine ...
NIDA Overview of Cocaine
... Cocaine Brief Description: Cocaine is a powerfully addictive central nervous system stimulant that is snorted, injected, or smoked. Crack is cocaine hydrochloride powder that has been processed to form a rock crystal that is then usually smoked. Street Names: Coke, snow, flake, blow More at Street T ...
... Cocaine Brief Description: Cocaine is a powerfully addictive central nervous system stimulant that is snorted, injected, or smoked. Crack is cocaine hydrochloride powder that has been processed to form a rock crystal that is then usually smoked. Street Names: Coke, snow, flake, blow More at Street T ...
Cocaine
Cocaine, also known as benzoylmethylecgonine or coke, is a strong stimulant mostly used as a recreational drug. It is commonly snorted, inhaled, or injected into the veins. Mental effects may include loss of contact with reality, an intense feeling of happiness, or agitation. Physical symptoms may include a fast heart rate, sweating, and large pupils. High doses can result in very high blood pressure or body temperature. Effects begin within seconds to minutes of use and last between five and ninety minutes. Cocaine has a small number of accepted medical uses such as numbing and decreasing bleeding during nasal surgery.Cocaine is addictive due to its effect on the reward pathway in the brain. After a short period of use, there is a high risk that dependence will occur. Its use also increases the risk of stroke, myocardial infarction, lung problems in those who smoke it, blood infections, and sudden cardiac death. Cocaine sold on the street is commonly mixed with local anesthetics, cornstarch, quinine, or sugar which can result in additional toxicity. Following repeated doses a person may have decreased ability to feel pleasure and be very physicially tired.Cocaine acts by inhibiting the reuptake of serotonin, norephinephrine, and dopamine. This results in greater concentrations of these three neurotransmitters in the brain. It can easily cross the blood–brain barrier and may lead to the breakdown of the barrier. Cocaine is made from the leaves of the coca plant which are mostly grown in South America. In 2013, 419 kilograms were produced legally. It is estimated that the illegal market for cocaine is 100 to 500 billion USD each year. With further processing crack cocaine can be produced from cocaine.After cannabis, cocaine is the most frequently used illegal drug globally. Between 14 and 21 million people use the drug each year. Use is highest in North America followed by Europe and South America. Between one and three percent of people in the developed world use cocaine at some point in their life. In 2013 cocaine use directly resulted in 4,300 deaths, up from 2,400 in 1990. The leaves of the coca plant have been used by Peruvians since ancient times. Cocaine was first isolated from the leaves in 1860. Since 1961 the international Single Convention on Narcotic Drugs has required countries to make recreational use of cocaine a criminal offence.