Alopecia areata update
... reported to be associated with AA include Down syndrome, Addison disease, autosomal recessive autoimmune polyglandular syndrome (APS-1) (chronic hypoparathyroidism-mucocutaneous candidiasis-autoimmune adrenal insufficiency), pernicious anemia, psoriasis, lupus, celiac disease, ulcerative colitis, an ...
... reported to be associated with AA include Down syndrome, Addison disease, autosomal recessive autoimmune polyglandular syndrome (APS-1) (chronic hypoparathyroidism-mucocutaneous candidiasis-autoimmune adrenal insufficiency), pernicious anemia, psoriasis, lupus, celiac disease, ulcerative colitis, an ...
Free PDF
... mucosal barrier function, such as heart failure or autism, can cause an increase in intestinal permeability. In some cases, such as in IBD and celiac disease, the permeability alteration could be the primary pathogenic cause. In others, such as in liver cirrhosis, it would lead to the translocation ...
... mucosal barrier function, such as heart failure or autism, can cause an increase in intestinal permeability. In some cases, such as in IBD and celiac disease, the permeability alteration could be the primary pathogenic cause. In others, such as in liver cirrhosis, it would lead to the translocation ...
Do all creatures possess an acquired immune system of some sort?
... It has been assumed that the innate sub-system is evolutionarily more ancient, and that variants of this system function in plants, invertebrates, and vertebrates [2]. In contrast to innate immunity, acquired immunity has been seen as an evolutionary innovation that is restricted to vertebrates. How ...
... It has been assumed that the innate sub-system is evolutionarily more ancient, and that variants of this system function in plants, invertebrates, and vertebrates [2]. In contrast to innate immunity, acquired immunity has been seen as an evolutionary innovation that is restricted to vertebrates. How ...
2003 ARS Immunology Research Workshop
... significant portion of the emerging or re-emerging infectious diseases that are threatening our people and public health systems; moreover, many zoonotic pathogens are also known as “select agents,” which by definition could be used for bioterrorism or warfare. This illustrates the need for new, imp ...
... significant portion of the emerging or re-emerging infectious diseases that are threatening our people and public health systems; moreover, many zoonotic pathogens are also known as “select agents,” which by definition could be used for bioterrorism or warfare. This illustrates the need for new, imp ...
Section 2 Specific Defense
... • B cells are white blood cells that are made in the bone marrow and complete their development there or in the spleen. B cells make antibodies. • T cells are cells that are made in the bone marrow but complete their development only after traveling to the thymus. T cells also participate in many im ...
... • B cells are white blood cells that are made in the bone marrow and complete their development there or in the spleen. B cells make antibodies. • T cells are cells that are made in the bone marrow but complete their development only after traveling to the thymus. T cells also participate in many im ...
MB_47_win
... • B cells are white blood cells that are made in the bone marrow and complete their development there or in the spleen. B cells make antibodies. • T cells are cells that are made in the bone marrow but complete their development only after traveling to the thymus. T cells also participate in many im ...
... • B cells are white blood cells that are made in the bone marrow and complete their development there or in the spleen. B cells make antibodies. • T cells are cells that are made in the bone marrow but complete their development only after traveling to the thymus. T cells also participate in many im ...
Fc lessons from murine mercury-induced autoimmunity. -receptors in systemic autoimmune conditions -
... Positive selection yields functional T cells that have the potential to recognize both self and foreign antigens. Therefore, negative selection exists to manage potentially self-reactive cells. Cells recognising self-antigens may still escape and enter the periphery. These cells are kept under contr ...
... Positive selection yields functional T cells that have the potential to recognize both self and foreign antigens. Therefore, negative selection exists to manage potentially self-reactive cells. Cells recognising self-antigens may still escape and enter the periphery. These cells are kept under contr ...
IVIg - NUH
... products are carefully screened and treated to prevent transmission of the hepatitis virus and other viruses. There have been no documented cases of the transmission of the virus that causes AIDS (HIV) through IVIG. There is also a small chance that you will have a severe allergic reaction to IVIG. ...
... products are carefully screened and treated to prevent transmission of the hepatitis virus and other viruses. There have been no documented cases of the transmission of the virus that causes AIDS (HIV) through IVIG. There is also a small chance that you will have a severe allergic reaction to IVIG. ...
Neuroendocrineimmune crosstalk in vertebrates and invertebrates
... one another, these systems communicate in an integrated fashion to coordinate suites of speciesappropriate physiological and behavioural responses. 2. Our understanding of how these three systems are coordinated remains incomplete, in part because the importance of the immune system as part of this ...
... one another, these systems communicate in an integrated fashion to coordinate suites of speciesappropriate physiological and behavioural responses. 2. Our understanding of how these three systems are coordinated remains incomplete, in part because the importance of the immune system as part of this ...
Combinations of type 1 diabetes, celiac disease and allergy
... that cowpox could be used as vaccine against human smallpox; however it was not until late 19th century that microorganisms were identified as the cause for infections. The function of the immune system is to protect the body from any foreign, and possibly harmful invader, like viruses, bacteria, fu ...
... that cowpox could be used as vaccine against human smallpox; however it was not until late 19th century that microorganisms were identified as the cause for infections. The function of the immune system is to protect the body from any foreign, and possibly harmful invader, like viruses, bacteria, fu ...
- World Journal of Gastroenterology
... The hygiene hypothesis was suggested to be responsible for the rising prevalence of various autoimmune and inflammatory disorders in developed populations, which are thought to result from the lack of early exposure to bacterial infections due to good sanitary conditions[9]. The changes in dietary a ...
... The hygiene hypothesis was suggested to be responsible for the rising prevalence of various autoimmune and inflammatory disorders in developed populations, which are thought to result from the lack of early exposure to bacterial infections due to good sanitary conditions[9]. The changes in dietary a ...
Pathogenic implications for autoantibodies against C-reactive protein and other acute phase proteins
... disease activity index; SS, primary Sjögren’s syndrome ...
... disease activity index; SS, primary Sjögren’s syndrome ...
Advanced Tests
... • Patients have a few antibody-producing B cells • Antibody production is defective ...
... • Patients have a few antibody-producing B cells • Antibody production is defective ...
curriculum vitae
... expression of the IL-12(p40) gene, suggesting a conserved pathway for the induction of organ-specific autoimmunity. J Leukoc Biol 69:440. 17. Kappos, L., G. Comi, H. Panitch, J. Oger, J. Antel, P. Conlon, and L. Steinman (Alleva included in The Altered Peptide Ligand in Relapsing MS Study Group). 20 ...
... expression of the IL-12(p40) gene, suggesting a conserved pathway for the induction of organ-specific autoimmunity. J Leukoc Biol 69:440. 17. Kappos, L., G. Comi, H. Panitch, J. Oger, J. Antel, P. Conlon, and L. Steinman (Alleva included in The Altered Peptide Ligand in Relapsing MS Study Group). 20 ...
Cutaneous Lupus Erythematosus
... Hallmark of SLE is the overproduction of autoantibodies by B-cells, some of which are directly pathogenic, including dsDNA, and Ro/SSA antibodies. Lupus patients have reduced clearance of immune complexes by the reticuloendothelial system Most of the tissue injury is due to B-cells due to immu ...
... Hallmark of SLE is the overproduction of autoantibodies by B-cells, some of which are directly pathogenic, including dsDNA, and Ro/SSA antibodies. Lupus patients have reduced clearance of immune complexes by the reticuloendothelial system Most of the tissue injury is due to B-cells due to immu ...
evolutionary causes and consequences of
... changes to blood vessels of the brain, which can lead to coma and death during cerebral malaria (Hunt & Grau 2003). In milder malaria, too, as parasites rupture out of the RBCs, the host responds with bursts of TNF-α that lead to fever and malaise. Hosts must therefore balance the need to kill paras ...
... changes to blood vessels of the brain, which can lead to coma and death during cerebral malaria (Hunt & Grau 2003). In milder malaria, too, as parasites rupture out of the RBCs, the host responds with bursts of TNF-α that lead to fever and malaise. Hosts must therefore balance the need to kill paras ...
Major Histocompatibility Complex Genomics and Human Disease
... modification (H3K27ac) ( green) for these cells analyzed by ChIP-seq. H3K27ac is an activating acetylation mark useful, for example, in identifying active enhancers. In terms of the recombination landscape of the MHC, data are shown for the deCODE recombination map (69) (dark brown), representing cal ...
... modification (H3K27ac) ( green) for these cells analyzed by ChIP-seq. H3K27ac is an activating acetylation mark useful, for example, in identifying active enhancers. In terms of the recombination landscape of the MHC, data are shown for the deCODE recombination map (69) (dark brown), representing cal ...
Probiotics for the Immune System
... irritable bowel syndrome (IBS)12 and certain types of colitis,5 which are not immune diseases. But, results of longer-term IBS studies vary.13 However, to date, probiotics have not definitively been shown to be effective in inflammatory bowel disease, Crohn’s disease or several other conditions.13 A ...
... irritable bowel syndrome (IBS)12 and certain types of colitis,5 which are not immune diseases. But, results of longer-term IBS studies vary.13 However, to date, probiotics have not definitively been shown to be effective in inflammatory bowel disease, Crohn’s disease or several other conditions.13 A ...
Artificial Immune Systems - Spletna učilnica FRI 16/17
... for the development of novel computer systems. Unlike some other bio-inspired techniques, such as genetic algorithms and neural networks, the field of AIS encompasses a spectrum of algorithms that exist because different algorithms implement different properties of different cells. All AIS algorithm ...
... for the development of novel computer systems. Unlike some other bio-inspired techniques, such as genetic algorithms and neural networks, the field of AIS encompasses a spectrum of algorithms that exist because different algorithms implement different properties of different cells. All AIS algorithm ...
A role for sex chromosome complement in the female bias in
... and 4Department of Pathology and Laboratory Medicine, University of California, Los Angeles, Los Angeles, CA 90095 ...
... and 4Department of Pathology and Laboratory Medicine, University of California, Los Angeles, Los Angeles, CA 90095 ...
Basophils, IgE, and Autoantibody-Mediated Kidney
... protein Ags, process, and present them to naive CD4 T cells via surface MHC class II (MHC II) (45). Mice immunized with OVA protein plus the protease papain developed OVAspecific Th2-type immune responses. Because papain injection recruits circulating basophils into the draining lymph nodes where ba ...
... protein Ags, process, and present them to naive CD4 T cells via surface MHC class II (MHC II) (45). Mice immunized with OVA protein plus the protease papain developed OVAspecific Th2-type immune responses. Because papain injection recruits circulating basophils into the draining lymph nodes where ba ...
Major Histocompatibility Complex (MHC)
... The duration of graft survival follows the order, xeno- < allo- < iso- = auto- graft. The time of rejection also depends on the antigenic disparity between the donors and recipient. MHC antigens are the major contributors in rejection, but the minor histocompatibility antigens also play a role. Reje ...
... The duration of graft survival follows the order, xeno- < allo- < iso- = auto- graft. The time of rejection also depends on the antigenic disparity between the donors and recipient. MHC antigens are the major contributors in rejection, but the minor histocompatibility antigens also play a role. Reje ...
Linking immune defenses and life history at the
... face similar classes of pathogens (for example, viruses, bacteria and macroparasites) and a similar frequency of challenge; these are followed by a discussion of the consequences of relaxing these assumptions. 1. Immunological variation at the population or species scale A hypothetical model relatin ...
... face similar classes of pathogens (for example, viruses, bacteria and macroparasites) and a similar frequency of challenge; these are followed by a discussion of the consequences of relaxing these assumptions. 1. Immunological variation at the population or species scale A hypothetical model relatin ...
Which Intrauterine Treatment for Autoimmune Congenital Heart Block?
... cytes [22]; they also demonstrated that these cross-reactive anti-La antibodies are able to bind the surface of myocytes in sections of normal fetus, but not of adult cardiac tissue, consistent with the reports that laminin molecules undergo conformational changes during development. These autoantib ...
... cytes [22]; they also demonstrated that these cross-reactive anti-La antibodies are able to bind the surface of myocytes in sections of normal fetus, but not of adult cardiac tissue, consistent with the reports that laminin molecules undergo conformational changes during development. These autoantib ...
- Wiley Online Library
... using Ward’s agglomerative hierarchical clustering method (R function: hclust), as Ward’s method is a preferred method in many biogeographic studies (Kreft and Jetz 2010). Regions were created by clustering countries based on their composition of diseases caused by pathogens (i.e., presence and abse ...
... using Ward’s agglomerative hierarchical clustering method (R function: hclust), as Ward’s method is a preferred method in many biogeographic studies (Kreft and Jetz 2010). Regions were created by clustering countries based on their composition of diseases caused by pathogens (i.e., presence and abse ...