Nebulizers: Principles and Performance
... aerosol generating devices. The physiologic benefits of metered-dose inhalers and nebulizers are virtually equivalent,3,4 and the choice of device is often based on clinician or patient preference rather than clear superiority of one approach over the other. Although cost savings have been suggested ...
... aerosol generating devices. The physiologic benefits of metered-dose inhalers and nebulizers are virtually equivalent,3,4 and the choice of device is often based on clinician or patient preference rather than clear superiority of one approach over the other. Although cost savings have been suggested ...
American Thoracic Society Documents
... Age/sex. In adults, there is no consistent relationship between exhaled NO level and age, but it has been reported that, in children, FeNO increases with age (82, 85, 86, 116). In adults, there are conflicting reports regarding the effects of sex (87, 117–119), menstrual cycle (117, 120–122), and pr ...
... Age/sex. In adults, there is no consistent relationship between exhaled NO level and age, but it has been reported that, in children, FeNO increases with age (82, 85, 86, 116). In adults, there are conflicting reports regarding the effects of sex (87, 117–119), menstrual cycle (117, 120–122), and pr ...
Approaches to the Management of Pulmonary Hypertension
... Copyright ©2007 American Academy of Pediatrics ...
... Copyright ©2007 American Academy of Pediatrics ...
... about twice that from a pressurized MDI, patients who generate flows of about 60 l·min-1 may reduce their prescribed dose of budesonide, without reducing therapeutic efficacy. Lung deposition of 99mTc-terbutaline sulphate, 0.5 mg, via Turbuhaler® at a PIF of about 60 l·min-1 through Turbuhaler®, has ...
Dean R Hess PhD RRT FAARC
... as well as physicians and nurses who interact with the patient. This assessment should not be limited to respiratory function since other factors also contribute to effective use of aerosol delivery systems. For example, all too often patients are prescribed the appropriate inhaled medication but do ...
... as well as physicians and nurses who interact with the patient. This assessment should not be limited to respiratory function since other factors also contribute to effective use of aerosol delivery systems. For example, all too often patients are prescribed the appropriate inhaled medication but do ...
The effect of amlodipine on respiratory and pulmonary vascular
... teratogenic risks. The subjects completed a medical questionnaire and underwent examination, and routine blood tests before being considered fit to enter the study. Subjects were excluded if: 1) there was any evidence of cardiac, pulmonary, renal or liver disease; 2) they were taking any drug that c ...
... teratogenic risks. The subjects completed a medical questionnaire and underwent examination, and routine blood tests before being considered fit to enter the study. Subjects were excluded if: 1) there was any evidence of cardiac, pulmonary, renal or liver disease; 2) they were taking any drug that c ...
Spacer inhalation technique and deposition of extrafine aerosol in asthmatic children
... Chlorofluorocarbon (CFC) propellants are being phased-out and replaced with hydrofluoroalkanes (HFA) in pressurised metered-dose inhalers (pMDI). Beclomethasone dipropionate (BDP) reformulated with HFA-134a (HFA-BDP or QVARTM; 3M Health Care Ltd, Loughborough, UK) produces an extrafine aerosol that ...
... Chlorofluorocarbon (CFC) propellants are being phased-out and replaced with hydrofluoroalkanes (HFA) in pressurised metered-dose inhalers (pMDI). Beclomethasone dipropionate (BDP) reformulated with HFA-134a (HFA-BDP or QVARTM; 3M Health Care Ltd, Loughborough, UK) produces an extrafine aerosol that ...
Metered-Dose Inhalers, Dry Powder Inhalers, and
... instruction can take 10 –30 minutes and should include demonstration, practice, and confirmation of patient performance (demonstration placebo units are available from many manufacturers for this purpose). Repeated instruction improves performance.22 Infants, young children, the elderly, and patient ...
... instruction can take 10 –30 minutes and should include demonstration, practice, and confirmation of patient performance (demonstration placebo units are available from many manufacturers for this purpose). Repeated instruction improves performance.22 Infants, young children, the elderly, and patient ...
The delivery of inhaled medication to the young child
... few minutes [10]. All nebulizer cups have some amount of medication remaining near the end of therapy, when aerosol generation becomes intermittent. This intermittent nebulization is referred to as sputtering; it has been documented that aerosol delivery to the patient declines by half within 20 sec ...
... few minutes [10]. All nebulizer cups have some amount of medication remaining near the end of therapy, when aerosol generation becomes intermittent. This intermittent nebulization is referred to as sputtering; it has been documented that aerosol delivery to the patient declines by half within 20 sec ...
TiO2-graphene oxide nanocomposite as advanced photocatalytic
... multi components peaks. The proper surface charge compensation was done by fitting C-C, C-H component of C 1 s peak to reference binding energy 284.5 eV. The atomic concentration of compounds was evaluated with relative sensitivity factors (RSF) defined in standard table of CasaXPS software. Diffuse ...
... multi components peaks. The proper surface charge compensation was done by fitting C-C, C-H component of C 1 s peak to reference binding energy 284.5 eV. The atomic concentration of compounds was evaluated with relative sensitivity factors (RSF) defined in standard table of CasaXPS software. Diffuse ...
The Inhalation of Drugs: Advantages and Problems
... Inhalation is a very old method of drug delivery, and in the 20th century it became a mainstay of respiratory care, known as aerosol therapy. Use of inhaled epinephrine for relief of asthma was reported as early as 1929, in England. An early version of a dry powder inhaler (DPI) was the Aerohalor, u ...
... Inhalation is a very old method of drug delivery, and in the 20th century it became a mainstay of respiratory care, known as aerosol therapy. Use of inhaled epinephrine for relief of asthma was reported as early as 1929, in England. An early version of a dry powder inhaler (DPI) was the Aerohalor, u ...
Influence of Nebulizer Type With Different Pediatric
... Education, Republic of China, and was performed at Chang Gung University. ...
... Education, Republic of China, and was performed at Chang Gung University. ...
... Entraining air through the nebulizer as the patient inhales has been known for some time to increase the output of drug without significantly affecting the particle size distribution of the aerosol [14, 15]. Recently a number of so-called Venturi nebulizers, based on this principle, have been design ...
Management of Peroxide Forming Chemicals
... This guideline outlines proper handling, use, and disposal of peroxide-forming chemicals at East Tennessee State University to prevent unsafe conditions and potential explosions. Peroxide-forming chemicals are compounds that may react with oxygen, even in low concentrations and at temperatures often ...
... This guideline outlines proper handling, use, and disposal of peroxide-forming chemicals at East Tennessee State University to prevent unsafe conditions and potential explosions. Peroxide-forming chemicals are compounds that may react with oxygen, even in low concentrations and at temperatures often ...
Acute and Chronic Effects of Inhalants in Intracranial Self
... available in legal, relatively inexpensive and common household products, which can be gases, liquids, aerosols or, in some cases, solids (mothballs)” (Cheong et al, 2006; Kong and Schmiesing, 2005; Weintraub et al, 2000). Further clouding the already socially constructed definition of inhalants is ...
... available in legal, relatively inexpensive and common household products, which can be gases, liquids, aerosols or, in some cases, solids (mothballs)” (Cheong et al, 2006; Kong and Schmiesing, 2005; Weintraub et al, 2000). Further clouding the already socially constructed definition of inhalants is ...
Class I: Flammable gases, vapors or liquids
... That is adjacent to a Class I, Zone 0 location from which ignitable concentrations of vapors could be communicated, unless communication is prevented by adequate positive pressure ventilation from a source of clean air and effective safeguards against ventilation failure are provided. Class I, Z ...
... That is adjacent to a Class I, Zone 0 location from which ignitable concentrations of vapors could be communicated, unless communication is prevented by adequate positive pressure ventilation from a source of clean air and effective safeguards against ventilation failure are provided. Class I, Z ...
Healthcare
... the same way, blood oxygenation initially falls on activity, then at rest. COPD is a common disease which affects one smoker in five after the age of 40. In France, 2,5-million people suffer from it. Of these, 30 000 are at the stage of chronic respiratory insufficiency and are treated at home with ...
... the same way, blood oxygenation initially falls on activity, then at rest. COPD is a common disease which affects one smoker in five after the age of 40. In France, 2,5-million people suffer from it. Of these, 30 000 are at the stage of chronic respiratory insufficiency and are treated at home with ...
Performance Comparison of Nebulizer Designs
... flow only, exhaled gas is routed out the expiratory valve in the mouthpiece, and aerosol is contained in the nebulizer chamber. Examples of breath-enhanced nebulizers include Pari LC Plus and Pari LCD. Coates et al10 and Dennis11 found better drug output with breath-enhanced nebulizers. Dosimetric n ...
... flow only, exhaled gas is routed out the expiratory valve in the mouthpiece, and aerosol is contained in the nebulizer chamber. Examples of breath-enhanced nebulizers include Pari LC Plus and Pari LCD. Coates et al10 and Dennis11 found better drug output with breath-enhanced nebulizers. Dosimetric n ...
In vitro comparison of heliox and oxygen in aerosol delivery using
... delivery with oxygen at low flow (3 L/min), the question arose as to the impact on aerosol delivery with the range of oxygen flows commonly delivered by HFNC to infants and small children (up to 6 L/min). As total flow through the HFNC increases, the inhaled dose decreases with both gases and a smaller ...
... delivery with oxygen at low flow (3 L/min), the question arose as to the impact on aerosol delivery with the range of oxygen flows commonly delivered by HFNC to infants and small children (up to 6 L/min). As total flow through the HFNC increases, the inhaled dose decreases with both gases and a smaller ...
The Influence of Breathing Pattern During
... BACKGROUND: Patients with obstructive airway conditions, including chronic obstructive pulmonary disease (COPD), use nebulizers for drug delivery. Tidal breathing patterns employed by patients during nebulized drug delivery may vary. It is unclear whether different breathing patterns affect the emit ...
... BACKGROUND: Patients with obstructive airway conditions, including chronic obstructive pulmonary disease (COPD), use nebulizers for drug delivery. Tidal breathing patterns employed by patients during nebulized drug delivery may vary. It is unclear whether different breathing patterns affect the emit ...
Testing of Nebulizers for Delivering Magnesium Sulfate to Pediatric
... is also rising. One option is to deliver MgSO4 via aerosol, but compared to most inhaled medications, which are active in the microgram dose range, the MgSO4 dose requirement is in the milligram range. This, along with inefficient aerosol delivery systems, may be the reason that some studies have fo ...
... is also rising. One option is to deliver MgSO4 via aerosol, but compared to most inhaled medications, which are active in the microgram dose range, the MgSO4 dose requirement is in the milligram range. This, along with inefficient aerosol delivery systems, may be the reason that some studies have fo ...
Peripheral deposition of a -protease inhibitor using commercial inhalation devices
... Patients with hereditary a1-proteinase inhibitor (a1-PI) deficiency suffer from the lack of a substance that protects the lung from neutrophil elastase, a powerful protease, which is capable of cleaving most proteins in the extracellular matrix. Due to a severely disturbed protease/antiprotease bala ...
... Patients with hereditary a1-proteinase inhibitor (a1-PI) deficiency suffer from the lack of a substance that protects the lung from neutrophil elastase, a powerful protease, which is capable of cleaving most proteins in the extracellular matrix. Due to a severely disturbed protease/antiprotease bala ...
Impurities: Guideline for Residual Solvents
... use of less toxic solvents and describes levels considered to be toxicologically acceptable for some residual solvents. Residual solvents in pharmaceuticals are defined here as organic volatile chemicals that are used or produced in the manufacture of drug substances or excipients, or in the prepara ...
... use of less toxic solvents and describes levels considered to be toxicologically acceptable for some residual solvents. Residual solvents in pharmaceuticals are defined here as organic volatile chemicals that are used or produced in the manufacture of drug substances or excipients, or in the prepara ...
The early evolution of nebulizers
... In the USA, at least two papers appeared in 1935 describing the use of glass nebulizers with a more concentrated solution of adrenalin. E. Matzger stated that the idea of inhaling adrenalin developed shortly after the drug was available for injection [18]. He referenced a paper from 1921 by A. Ephra ...
... In the USA, at least two papers appeared in 1935 describing the use of glass nebulizers with a more concentrated solution of adrenalin. E. Matzger stated that the idea of inhaling adrenalin developed shortly after the drug was available for injection [18]. He referenced a paper from 1921 by A. Ephra ...