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AP Biology Mrs. Morton Study Guide: The Cell Cycle, Ch.12 Key terms: Cell division Cell cycle Genome Chromosome Somatic cell Gamete Chromatin Sister chromatid Centromere Mitosis Cytokinesis Meiosis Mitotic (M) phase Interphase G phase S phase G phase Prophase Prometaphase Metaphase Anaphase Telophase Mitotic spindle centrosome kinetochore metaphase plate cleavage cleavage furrow cell plate binary fission origin of replication cell cycle control system checkpoint G phase cyclin cyclin-dependent kinase (Cdk)) MPF growth factor density-dependent inhibition anchorage dependence transformation tumor benign tumor malignant tumor metastasis Objectives: 1. Explain hoe cell division functions in reproduction, growth, and repair. 2. Describe the structural organization of the genome. 3. Explain the difference between a chromatid and a chromosome. 4. Describe the major events of cell division that enable the genome of one cell to be passed on to two daughter cells. 5. Describe the events in each of the following phases of the cell cycle; G1, S, G2, and M. 6. List the phases of mitosis and describe the events characteristic of each phase. 7. Recognize the phases of mitosis from diagrams and micrographs. 8. Compare cytokinesis in animals and plants. 9. Describe the process of binary fission in bacteria and how this process may have evolved in eukaryotic mitosis. 10. Describe the role of checkpoints, cyclin, Cdk, and MPF in the cell cycle control system. 11. Describe the internal and external factors that influence the cell cycle control system. 12. Explain how the abnormal cell division of cancerous cells differs from normal cell division.