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Table S3 Characteristics of studies with significant evidence of TCM treatments for cancer published in Chinese (5 papers)
study ID
funding
participants
randomization
blinding to
(No.)
method
whom
recommendation for
intervention VS control
outcomes
main results
generalization stated
in the paper (yes/no)
survival, relapse,
Huang S
2011
not reported
acute leukemia
computer
(20 VS 21)
software
Fufang Zhebei Granule +
12
chemotherapy VS
chemotherapy + Placebo
clinical
The median survival time did not show significant
symptom,
difference between treatment and control group, but the
laboratory
relapse rate in 3 months, 6 months and 1 year was lower
indexes, relief
in treatment group than in control group. (p<0.05)
no
time
Science
Xu ZY
2007
Technology
Development
Funding of
Shanghai City
Key Program of
Wang LF
Science
2010
Development of
Shanghai City
advanced
non-small cell
lung cancer (60
envelope
34
VS 56)
advanced lung
cancer (44 VS
random table
46)
single
blinding
Kangliu Zengxiao Fang + Yan
survival, quality
the median survival time in treatment group was 15.57
Ning Decoction +
of life, clinical
months, and in control group 11.17 months (p<0.01),
chemotherapy VS
symptoms, side
treatment group showed higher quality of life after
chemotherapy
effects
treatment (p<0.01)
tumor size,
median survival: treatment group 16.63 months, control
Yan Ning Decoction +
survival, quality
group 11.60 months (p<0.05), and treatment group
chemotherapy VS
of life, clinical
showed higher survival rate for 1 year, 3 year and 5
chemotherapy
symptom, side
years (p<0.05), and better improvement of quality of life
effects
(p<0.05) and clinical symptoms (p<0.05)
treatment I group (Jianpi
Liu HT
2009
breast cancer
not reported
(200 VS 200 VS
200)
SAS computer
patients,
software
physicians
Yishen Capsule VS treatment
II group (Yangyin Shengxue
Mixture) VS control group
(placebo)
no
no
TCM syndrome
related
symptoms,
quality of life,
immune
function, relapse
two herbal medicine showed significant improvement of
clinical symptoms, quality of life, immune function and
one year, two year survival
yes
and metastasis,
survival and
survival time
without disease
TCM group (individualized
decoction based on syndrome
differentiation + herbal
injection + standard herbal
decoction + routine treatment)
non-small cell
LI LN 2003
not reported
lung cancer (40
VS 40 VS 40)
computer
software
1
VS Conventinal medicine
TCM group: 84.4% 0.5 year survival and 18.1% 1 year
group (chemotherapy + herbal
survival; conventional medicine group: 82.5% 0.5 year
decoction placebo + routine
survival time
survival and 20.6% 1 year survival; intergrative group:
treatment) VS integrative
92.5% 0.5 year survival and 42.7% 1 year survival
group (individualized decoction
(p<0.05)
based on syndrome
differentiation + herbal
injection + standard herbal
decoction +chemotherapy +
routine treatment)
yes
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