Download Online Appendix 4: Table shows the gene ontology (GO) terms and

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Supplementary Table S4: Table shows the gene ontology (GO) terms and pathways identified by gene ontology and functional
analyses (DAVID) that were overrepresented (P-value < 0.01) in our list of 204 significantly differentially expressed transcripts after
bariatric surgery. GO terms discussed in the manuscripts are shown in bold.
20 Transcripts were found to be best correlated with weight changes, only 18 were recognized and included in gene ontology analysis.
Term Resource and ID
GO:0006695
GO:0016126
GO:0008610
GO:0008203
GO:0006694
GO:0016125
KEGG_PATHWAY
GO:0008202
GO:0044255
Term Name
Cholesterol biosynthetic process
Sterol biosynthetic process
Lipid biosynthetic process
Cholesterol metabolic process
Steroid biosynthetic process
Sterol metabolic process
Biosynthesis of steroids
Steroid metabolic process
Cellular lipid metabolic process
Count
3
3
4
3
3
3
2
3
4
% of genes involved/total genes
17.65%
17.65%
23.53%
17.65%
17.65%
17.65%
11.76%
17.65%
23.53%
P-Value
1.23E-04
2.12E-04
6.41E-04
1.06E-03
1.29E-03
1.39E-03
5.70E-03
6.22E-03
6.46E-03
35 Transcripts were found to be best correlated with fasting plasma glucose changes, only 32 were recognized and included in gene ontology analysis.
Term Resource and ID
GO:0006139
GO:0016070
GO:0005634
GO:0010467
GO:0006350
GO:0043283
GO:0006351
GO:0032774
GO:0003677
GO:0045449
GO:0003676
GO:0019219
SP_PIR_KEYWORDS
GO:0010468
SP_PIR_KEYWORDS
SP_PIR_KEYWORDS
SP_PIR_KEYWORDS
GO:0031323
Term Name
Nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
RNA metabolic process
Nucleus
Gene expression
Transcription
Biopolymer metabolic process
Transcription, DNA-dependent
RNA biosynthetic process
DNA binding
Regulation of transcription
Nucleic acid binding
Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
Nucleus
Regulation of gene expression
DNA-binding
Transcription regulation
Transcription
Regulation of cellular metabolic process
Count
14
12
15
13
11
15
10
10
9
10
11
10
12
10
8
8
8
10
% of genes involved/total genes
43.75%
37.50%
46.88%
40.62%
34.38%
46.88%
31.25%
31.25%
28.12%
31.25%
34.38%
31.25%
37.50%
31.25%
25.00%
25.00%
25.00%
31.25%
P-Value
6.47E-04
8.27E-04
9.00E-04
1.14E-03
1.46E-03
2.98E-03
3.45E-03
3.47E-03
4.64E-03
4.67E-03
4.93E-03
5.47E-03
5.76E-03
7.06E-03
7.15E-03
7.28E-03
7.96E-03
9.25E-03
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