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Plant Cell vs. Animal Cell Structure Plant Cell Animal Cell Cell Membrane Cell Wall Central Vacuole Centriole Chloroplasts Chromosomes Cytoplasm Endoplasmic Reticulum Golgi bodies Lysosome Messenger RNA Mitochondria Nucleolus Nucleus Ribosome Vacuoles Four Major Differences: 1. The plant cell has chloroplasts and the animal cell does not. 2. The plant cell has a cell wall and the animal cell does not. 3. The plant cell has one large central vacuole and the animal cell has many small vacuoles. 4. The plant cell is more oval in shape and the animal cell is more circular.