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Neurotransmitters Small-Molecule Transmitters Name Location(s) Function(s) Acetylcholine Acetylcholine Junctions with motor effectors (muscles, glands) Ex: neuromuscular junction; Brain Serotonin Amines Regions of CNS Dopamine Amines Brain; autonomic system Epinephrine Amines Norepinephrine Amines CNS, sympathetic division of ANS CNS, sympathetic division of ANS Glutamate Amino Acid CNS GABA Amino Acid Brain Excitatory (neuromuscular junction of skeletal muscles); inhibitory (neuromuscular junction of cardiac muscle tissue); involved in memory Mostly inhibitory; moods, emotions, sleep Mostly inhibitory; emotions/moods; regulating motor control Deficiencies = Parkinson’s Disease Excitatory or inhibitory; secreted by adrenal gland Excitatory or inhibitory; regulates sympathetic effectors; involved in emotional responses Most common excitatory NT in CNS Most common inhibitory NT in brain Large-molecule Transmitters Name Endorphins Class Class Neuropeptides Location(s) CNS; retina; intestinal tract Function(s) Mostly inhibitory; act like opiates to block pain