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Name________________________________________
Date_______
Model 7: Polygenic Inheritance
Exercise 10
Differences in skin color are largely due to differences in the amount of melanin, a dark
pigment produced by skin cells. At least three genes control the synthesis of melanin.
Each gene has two forms: an allele for high melanin production, or dark skin (A,B,C),
and an allele for low melanin production, or light skin (a,b,c). Each dark skin allele
(A,B,C) in the genotype adds a small but equal amount of pigment to the skin. There
are seven different shades of skin color ranging from very dark (AABBCC) to very light
(aabbcc). Most individuals produce a medium amount of melanin and are of
intermediate skin color (AaBbCc).
The following Punnett square shows the possible offspring from a cross between two
individuals of intermediate skin color.
AaBbCc X AaBbCc
Gametes
ABC
ABc
AbC
Abc
aBC
aBc
abC
abc
ABC
ABc
AbC
Abc
aBC
aBc
abC
abc
AABBCC
AABBCc
AABbCC
AABbCc
AaBBCC
AaBBCc
AaBbCC
AaBbCc
AABBCc
AABBcc
AABbCc
AABbcc
AaBBCc
AaBBcc
AaBbCc
AaBbcc
AABbCC
AABbCc
AAbbCC
AAbbCc
AaBbCC
AaBbCc
AabbCC
AabbCc
AABbCc
AABbcc
AAbbCc
AAbbcc
AaBbCc
AaBbcc
AabbCc
Aabbcc
AaBBCC
AaBBCc
AaBbCC
AaBbCc
aaBBCC
aaBBCc
aaBbCC
aaBbCc
AaBBCc
AaBBcc
AaBbCc
AaBbcc
aaBBCc
aaBBcc
aaBbCc
aaBbcc
AaBbCC
AaBbCc
AabbCC
AabbCc
aaBbCC
aaBbCc
aabbCC
aabbCc
AaBbCc
AaBbcc
AabbCc
Aabbcc
aaBbCc
aaBbcc
aabbCc
aabbcc
The offspring of this cross exhibit seven shades of skin color based on the number of
dark skin alleles in each genotype.
©Modeling Instruction Program
1
Model 7 - Heredity
Name________________________________________
Date_______
Model 7: Polygenic Inheritance
Exercise 10
Fill in the information in the following chart to determine the probability
that the children might have a different skin color than the parents.
Example: Count the number of boxes with 3 dominant alleles, write it in the correct
column and then divide that number by 64 to get your % probability. Round the % to the
nearest hundredth (.01) place.
Skin color
3 shades darker
2 shades darker
1 shade darker
Same as parents
1 shade lighter
2 shades lighter
3 shades lighter
# of
dark
alleles
# of times that
sequence
appears in
punnett square
Probability (%)
6
5
4
3
2
1
0
Questions
1. Each parent produces eight different types of gametes, which can combine in 64
different ways. Complete the following table:
2. How many of these 64 possible offspring have skin that is darker than their
parents? ____
3. Each of these three genes has two alleles. Are the dark skin alleles dominant to
the light skin alleles?
_____________________________________________________________
4. There are more than 7 shades of skin color. Offer an explanation.
________________________________________________________________
Copyright © 2008 by the National Center for Case Study Teaching in Science. Please see our usage
guidelines, which outline our policy concerning permissible reproduction of this work.
©Modeling Instruction Program
2
Model 7 - Heredity
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