Download Obrazovanje:

SNEŽANA SAVIĆ
Personal info:




Date of birth: 2.1.1971.
Place of resident: Belgrade
Phone: 00381643073767
E-mail: [email protected]
Work experience – University of Belgrade – Faculty of Pharmacy:





2012 – present: Associated professor at the Department of Pharmaceutical
Technology and Cosmetology, Faculty of Pharmacy, University of Belgrade
2006 – Docent/Assistant professor at the Department of Pharmaceutical
Technology and Cosmetology, Faculty of Pharmacy, University of Belgrade
2003 – Research assistant at the Department of Pharmaceutical Technology and
Cosmetology, Faculty of Pharmacy, University of Belgrade
2001 – Associate at the Department of Pharmaceutical Technology and
Cosmetology , Faculty of Pharmacy, University of Belgrade
1994 – 2001 – Associate at the pharmaceutical company Galenika a.d., Belgrade,
Research Institute, Department for development of final technologies
Work experience – visiting professorships:



2011-2013 – Visiting professor at the Department of Pharmaceutical Technology,
Faculty of Pharmacy, University of Ljubljana, Slovenia
2010 – Present – Visiting professor at the Faculty of Pharmacy in Podgorica
(Montenegro) and at the Department of Pharmacy, Faculty of Medicine in Banja
Luka (Republic of Srpska)
2007/2008 – Visiting professor at the Faculty of Technology in Leskovac,
University of Niš (Serbia)
Education:


2013 – Specialist of Pharmaceutical technology in the field of Pharmaceutical
biotechnology, Faculty of Pharmacy, University of Belgrade
2004 – PhD degree in the field of Pharmaceutical Technology, Faculty of
Pharmacy, University of Belgrade
1


2001 – Master of Science in the field of Cosmetology, Faculty of Pharmacy,
University of Belgrade
1994 – Degree in Pharmacy, average grade 9.60 (out of 10.00)
Professional development:











2015 – Training course of the German Society of Cosmetic Chemists (DGK) on
Basic Principles of Safety Assessment of Cosmetics “General and Systemic
Toxicology” at Cologne (Germany) – certificate for Safety Assessor;
2014 - Heinz Maurer Award 2014 Scientific Symposium “Review and Preview in
Science for Healthy Skin” Boppard (Germany);
2014 – Training course in National Institute for Bioprocessing Research and
Training “Bioprocessing Training Course”, May 26-28, 2014, Dublin, Ireland –
within the frame of EU funded project: LLP Knowledge Alliance Project 539247LLP-1-2013-1-IE-ERASMUS-EKA, LIAT-Ph:Linking Industry and Academia in
Teaching Pharmaceutical Development and Manufacture;
2013 – Training course of the German Society of Cosmetic Chemists (DGK) on
Basic Principles of Safety Assessment of Cosmetics (Safety Assessment Courses,
April, 25-26, Frankfurt, Germany) – certificate for Safety Assessor;
September 2012 – Research stay at the Institut für Pharmazeutische Technologie,
Eberhard-Karls Universität, Tübingen, Germany, during realization of the project:
“Development of micro- and nanosystems for drugs with anti-inflammatory effect
and methods for their characterization” (Ministry of education, science and
technological development of RS funded);
September 2011 - Research stay at the Institute of Pharmaceutical Technology,
Technical University of Braunschweig, Germany and at the Institut für
Pharmazeutische Technologie, Eberhard-Karls Universität, Tübingen, Germany,
during realization of the project: “Development of micro- and nanosystems for
drugs with anti-inflammatory effect and methods for their characterization”
(funded by the Ministry of education, science and technological development of
the Republic of Serbia);
2007 – Research stay during postdoctoral studies at the Institute of
Pharmaceutical Technology, Technical University of Braunschweig, Germany
and at the Institut für Pharmazeutische Technologie, Eberhard-Karls Universität,
Tübingen, Germany (DAAD funded program “Research Stays and Visits of
University Academics”);
2005 – Research stay at the London College of Fashion (Great Britain);
2003/2004 – Research stay during PhD studies at the Institute of Pharmaceutical
Technology, Technical University of Braunschweig, Germany (DAAD funded);
2003 – Good Manufacturing Practice and technical inspection course;
1996 – passed Pharmacist Licensing Exam.
Scientific/research activities
S. Savic is the author/co-author of more than 280 papers, presentations (oral or
poster) and technical solutions: 7 chapters in international books (M13), 4 chapters in
national monographs/books (M45), abobe 50 scientific papers in international peer
2
review journals (M21, M22 and M23 categories), 4 invited lectures at international
meetings (M31 and M32), 12 technical solutions (M82 and M85 categories), 1 patent
application etc…
Total number of citation: 614, h-index: 16
Projects:







2013 - 2015 - Bilateral project with the University of Tübingen, Germany:
Formulation of micro-, nano- and surfactant-free emulsion systems for poorly
water soluble drugs: development and optimization of ex vivo and in vivo
evaluation methods (coordinated by Prof. dr Snežana Savić and Prof. dr Rolf
Daniels);
2013 - 2016 - LIAT-Ph: Linking Industry and Academia in Teaching
Pharmaceutical Development and Manufacture, funded with the support of the
Lifelong Learning Programme of the EU;
2011 – 2015 –Head of the project within the Technological Development
Programme: “Development of micro- and nanosystems for drugs with antiinflammatory effect and methods for their characterization”, financed by the
Ministry of education, science and technological development, Republic of Serbia
(ТR 34031);
2011 – 2015 – Associate at the project in Fundamental Research Programme:
“Developing molecules with anti-inflammatory and cardioprotective action:
structural modifications, modelling, physical and chemical characterisation and
formulation testing", financed by the Ministry of education, science and
technological development, Republic of Serbia (OI 172041);
2008 – 2010 - Associate at the project: “Development and characterization of
colloidal drug carriers with antiinflammatory effect” (ТR 19058);
2006 – 2010 – Associate at the project: “ Behavioral characterization of novel
synthesized substances which are selective for some subtypes of GABA A” (ОI
145022);
2005 – 2007 – Associate at the project: “Immunomodulation preparations based
on calf thymus extract for the use in humane and veterinary medicine”.
Scholarships and awards:



2007 - German foundation DAAD scholarship through program "Research Stays
and Visits of University Academics" during postdoctoral studies at the Institute of
Pharmaceutical Technology, Technical University of Braunschweig, Germany
and at the Institut für Pharmazeutische Technologie, Eberhard-Karls Universität,
Tübingen, Germany
2003/2004 – German foundation DAAD scholarship for six-month research stay
in Germany, at the Institute of Pharmaceutical Technology, Technical University
of Braunschweig
2003/2004 – FIP Foundation for Education and Research - FIP Fellowship, for
doctoral education abroad
3



2002 – FIP Foundation for Education and Research - International Travel
Scholarship
1997 – FIP Foundation for Education and Research – Development Grant
1992 – 1995 – Scholarship for undergraduate and postgraduate – master students
awarded by the Republic of Serbia foundation for talented youth.
Teaching:








Integrated academic studies: Teaching professor at courses: Pharmaceutical
technology I, Pharmaceutical technology II, Cosmetology, and Introduction to
pharmaceutical biotechnology
Specialist academic studies: Teaching professor at different modules:
Pharmaceutical Technology, Cosmetology, Pharmacotherapy in pharmaceutical
practice, Biological drugs, and Releasing medicines onto the market
PhD studies: Teaching professor of a few courses on modules: Pharmaceutical
technology and Cosmetology, Head of the PhD course in Cosmetology
Invitation lectures at specialization studies: module Pharmaceutical management
and marketing, PhD studies: module Pharmacology, and specialization studies at
the Faculty of Medicine, University of Belgrade.
Mentor of 2 defended PhD thesis in the field of Cosmetology and 4 PhD thesis in
the field of Pharmaceutical Technology; a member of the commission for the
defense of 3 PhD thesis in the field of Pharmaceutical Technology and 1 PhD
thesis in the field of Cosmetology..
Mentor of one M.S. thesis in Cosmetology.
Mentor of more than 15 defended specialization thesis and a member of the
commission for the defense of a large number of specialization thesis in the field
of Pharmaceutical Technology, Cosmetology and Pharmaceutical Management
and Marketing.
Mentor and member of the commission for evaluation and defense of numerous
graduated/master thesis.
Educational literature:


Pharmaceutical Technology I, Gordana Vuleta, Jela Milić, Marija Primorac,
Snežana Savić, 1st edition, Faculty of Pharmacy, Belgrade, 2012.
Handbook for Cosmetology, Dragana Vasiljević, Snežana Savić, Ljiljana
Đorđević, Danina Krajišnik, Nauka, Beograd, 1st edition in 2007 and 2nd edition in
2009.
Selected publications:
1. Lukic M, Pantelic I, Savic S. An overview of novel surfactants for formulation of
cosmetics with certain emphasis on acidic active substances. Tensides Surfactants
Detergents olume 53, Issue 1, January-February 2016, Pages 7-19.
2. Isailovic T, Djordjevic S, Markovic B, Randjelovic D, Cekic N, Lukic M, Pantelic I,
Daniels R, Savic S. Biocompatible Nanoemulsions for Improved Aceclofenac Skin
4
Delivery: Formulation Approach Using Combined Mixture-Process Experimental
Design. Journal of Pharmaceutical Science; Volume 105, Issue 1, January 2016, Pages
308-323DOI: 10.1002/jps.24706.
3. Todosijević M, Savić M, Batinić B, Marković B, Gašperlin M, Ranđelović D, Lukić
M, Savić S. Biocompatible microemulsions of a model NSAID for skin delivery: A
decisive role of surfactants in skin penetration/irritation profiles and pharmacokinetic
performance. International Journal of Pharmaceutics Volume 496, Issue 2, 30 December
2015, Pages 931-941.
4. Djordjevic S, Cekic N, Savic M, Isailovic T, Randjelovic D, Markovic B, Savic S,
Timic-Stamenic T, Daniels R, Savic S. Parenteral nanoemulsions as promising carriers
for brain delivery of risperidone: Design, characterization and in vivo pharmacokinetic
evaluation. International Journal of Pharmaceutics 2015; 493 (1-2): 40-54.
5. Savic S, Pantelic I, Lukic M, et al. Behind the Alkyl Polyglucoside-based structures:
Lamellar liquid crystalline and lamellar gel phases in different emulsion systems. In:
Pantelic I (ed) Alkyl Polyglucosides: From natural-origin surfactants to prospective
delivery systems. Cambridge: Woodhead Publishing; 2014. p 21-52.
6. Lukic M, Pantelic I, Savic S. Emulsion systems: From stability concerns to sensory
propertie. In: Pantelic I (ed). Alkyl Polyglucosides: From natural- origin surfactants to
prospective delivery systems. Cambridge: Woodhead Publishing, 2014; p. 73-105.
7. Tasic-Kostov M, Vesic S, Savic S. Objective skin performance evaluation: How mild
are the APGs to the skin? In: Pantelic I (ed). Alkyl Polyglucosides: From natural- origin
surfactants to prospective delivery systems. Cambridge: Woodhead Publishing, 2014; p.
135-162.
8. Todosijević MN, Cekić ND, Savić MM., Gašperlin M, Randelović DV, Savić SD.
Sucrose ester-based biocompatible microemulsions as vehicles for aceclofenac as a
model drug: formulation approach using D-optimal mixture design. Colloid Polym Sci
2014;292(12):3061–3076.
9. Kovacevic A, Mueller RH, Savic SD, Vuleta GM, Keck CM. Solid lipid nanoparticles
(SLN) stabilized with polyhydroxy surfactants: Preparation, characterization and physical
stability investigation. Colloid and Surfaces A-Physicochemical and Engineering 2014;
444: 15-25.
10. Pantelic I, Lukic M, Markovic B, Daniels R, Vesic S, Vuleta G, Savic S. Effect of
small changes in natural origin-based emulsion systems on hydrocortisone skin
absorption and performance: a comparison of two in vivo methods. Pharmaceutical
Development and Technology 2014; 19 (1): 55–64.
11. Đorđević SM, Radulović TS, Cekić ND, Ranđelović DV, Savić MM, Krajišnik DR,
Milić JR, Savić SD. Experimental design in formulation of diazepam nanoemulsions:
Physicochemical and pharmacokinetic performances. Journal of Pharmaceutical Sciences
2013; 102 (11): 4159–4172.
12. Calija B, Cekić N, Savić S, Daniels R, Marković B, Milić J. pH-sensitive
microparticles for oral drug delivery based on alginate/oligochitosan/Eudragit(®) L10055 "sandwich" polyelectrolyte complex. Colloids Surf B Biointerfaces. 2013; 110: 395402.
13. Lukic M, Jaksic I, Krstonosic V, Dokic L, Savic S. Effect of Small Change in Oil
Phase Composition on Rheological and Textural Properties of w/o Emulsion. Journal of
Texture Studies Volume 44, Issue 1, February 2013, Pages 34-44.
5
14. Jaksic I, Lukic M, Malenovic A, Reichl S, Hoffmann C, Müller-Goymann C, Daniels
R, Savic S. Compounding of a topical drug with prospective natural surfactant-stabilized
pharmaceutical bases: physicochemical and in vitro/in vivo characterization. A
ketoprofen case study. Eur J Pharm Biopharm 2012; 80 (1): 164-175.
53.
15. Lukic M, Jaksic I, Krstonosic V, Cekic N, Savic S. A combined approach in
characterization of an effective w/o hand cream: the influence of emollient on textural,
sensorial and in vivo skin performance. Int J Cosmet Sci. 2012 Apr;34(2):140-9. doi:
10.1111/j.1468-2494.2011.00693.x.
16. Kovacevic A, Savic S, Vuleta G, Mueller R, Keck C. Polyhydroxy surfactants for the
formulation of lipid nanoparticles (SLN and NLC): Effects on size, physical stability and
particle matrix structure, Int J Pharm 2011; 406 (1-2): 163-172.
17. Savic S, Lukic M, Jaksic I, Reichl S, Tamburic S, Müller-Goymann C. An alkyl
polyglucoside-mixed emulsifier as stabilizer of emulsion systems: The influence of
colloidal structure on emulsions skin hydration potential, J Colloid Interface Sci 2011;
358: 182–191.
18. Savic S, Tamburic S, Savic M. From conventional towards new - natural surfactants
in drug delivery systems design: current status and perspectives (Review), Expert
Opinion on Drug Delivery 2010; 7 (3): 353-369.
19. Tasic-Kostov M, Savic S, Lukic M, Tamburic S, Pavlovic M, Vuleta G. Lactobionic
acid in a natural alkylpolyglucoside-based vehicle: assessing safety and efficacy aspects
in comparison to glycolic acid. J Cosmet Dermatol 2010; 9 (1): 3-10.
20. Savic S, Weber C, Tamburic S, Savic M, Müller-Goymann C. Topical vehicles based
on natural surfactant/fatty alcohols mixed emulsifier: The influence of two polyols on the
colloidal structure and in vitro/in vivo skin performance. J Pharm Sci 2009; 98: 2073-90.
21. Savić S, Weber C, Savić MM, Müller-Goymann C. Natural surfactant-based topical
vehicles for two model drugs: Influence of different lipophilic excipients on in vitro/in
vivo skin performance. Int J Pharm. 2009; 381: 220-30.
22. Savić S, Tamburić S, Jančić B, Milić J, Vuleta G. The impact of urea on colloidal
structure of alkylpolyglucoside-based emulsions: physico-chemical and in vitro/vivo
characterisation. In: T.F. Tadros (ed.), Colloid and Interface Science Series Vol. 4,
Wiley-VCH Verlag GmbH&Co.KGaA, Weinheim, Germany (2008), pp. 259-274.; ISBN
978-3-527-31464-5.
Activities at the Faculty:



2013 – Member of the working group for the development of the Innovative
Center at the Faculty of Pharmacy, University of Belgrade (named as a director in
August, 2013).
2008 – 2015 – Collaboration with more than 25 students through Center of
students scientific research at the Faculty of Pharmacy, University of Belgrade;
Mentor of the Students' research project which was awarded by the University of
Belgrade for being the best students' research project in the field of biomedicine.
2010 – Present – Member of Committee for PhD studies at the Faculty of
Pharmacy, University of Belgrade.
6

2005 – 2006 – Member of the Committee for the evaluation of the educational
and the pedagogical work of professors and assistants.
Activities within the wider academic community:






2012 – 2013 and 2006 – 2007 – Member of the working group at the Ministry of
health, Republic of Serbia for development of Regulations on health and safety of
general use products (cosmetic products)
2013 – Expert for Medicines and Medical devices agency in Serbia and in
Montenegro
2012 – 2013 – Member of the working group at the Medicines and Medical
Devices Agency of Serbia for supplementation of Formulae magistrales
Member of the Pharmaceutical Association of Serbia and member of the
International Federation of Galenic and Industrial Pharmacy
Gave more than 30 lectures for accredited courses of Continuous education at the
Faculty of Pharmacy, University of Belgrade, as well as lectures at congresses and
symposiums organized by Pharmaceutical Association of Serbia, Serbian
Apothecary Society, Serbian Medical Society in the field of Pharmaceutical
Technology or Cosmetology
Reviewer for various international and national journals (Journal of Controlled
Release; Colloid & Surfaces B: Biointerfaces; International Journal of
Pharmaceutics, European Journal of Pharmaceutics and Biopharmaceutics,
Journal of Pharmacy and Pharmacology, Drug Delivery, Drug Development and
Industrial Pharmacy; Journal of Drug Delivery and Science Technology,
Therapeutic
Delivery;
Journal
of
Surfactants
and
Detergents;
Household&Personal Care; Vojno-Sanitetski pregled, Arhiv za farmaciju)…
7