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The Cell Cycle
Level 1 Items
1. Identify the roles of cell division
2. Identify the composition of a chromosome.
3. Recognize the phases of the cell cycle.
4. Identify the stages and characteristics of Interphase.
5. Identify the stages and characteristics of Mitosis.
6. Recognize the mechanisms of Cytokinesis.
7. Recognize factors that control cell division.
8. Recognize the results when the regulation of cell division goes wrong.
Outline
A. Roles of Cell Division
1. Reproduction
2. Growth
3. Repair
B. Chromosomes
1. Genome
2. Molecular composition
a. DNA
b. Protein
3. Structure
a. Centromere
b. Sister chromatids
C. The Cell Cycle
1. Interphase
a. G1 phase
1. Definition
2. Characteristics
b. S phase
1. Definition
2. Characteristics
c. G2 phase
1. Definition
2. Characteristics
2. Mitotic Phase
a. Prophase
1. General Characteristics
2. Chromosome Formation
3. Spindle Formation
b. Metaphase
1. Characteristics
2. Chromosome Arrangement
c. Anaphase
1. Characteristics
2. Chromosome Movement - Kinetochores
3. Cell Elongation
d. Telophase
1. Characteristics
2. Nuclear Envelope Formation
3. Cytokinesis
a. Animal Cells
b. Plant Cells
4. Mitosis without Cytokinesis
C. Regulation of the Cell Cycle
1. Checkpoints
a. Definition
b. G1 restriction point
c. Go phase
2. G2 checkpoint
a. MPF
b. cdk
c. Cyclin
3. Growth Factors
a. Definition
b. Examples
1. PDGF
2. Density Dependent Inhibition
3. Anchorage Dependence
4. Abnormal Growth – Cancer etc.
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