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LAB 6 Endocrine & Lymphatic Systems Major Endocrine Glands Endocrine Glands Within the Brain Pineal Gland Hypothalamus Pituitary Stalk Pituitary Gland -Anterior -Posterior • 3. Sphenoid Bone Sella Turcica (Turkish Saddle) = Houses Pituitary gland Pituitary gland Hormones Anterior Posterior • Growth Hormone (GH) • Antidiuretic hormone (ADH) • Oxytocin (OT) • Thyroid Stimulating Hormone (TSH) • Adrenocorticotropic hormone (ACTH) • Luteinizing hormone (LH) • Follicle Stimulating Hormone (FSH) • Prolactin (PRL) Anterior Pituitary Hormones 1. GH – stimulates cell growth & division 2. TSH – Stimulates thyroid gland 3. ACTH – Stimulates adrenal cortex 4. FSH/LH- Stimulates ovaries & testes 5. PRL – stimulates lactation in mammary glands Posterior Pituitary Hormones 1. ADH – Promotes water reabsorption by kidneys 2. Oxytocin- Stimulates uterine contractions Pineal gland • Secretes hormone melatonin – Regulates circadian rhythm (sleep/wake cycle) Larynx Models Thyroid Gland Larynx Model Posterior View Parathyroid Glands Thyroid Gland Hormones: 1. T3 & T4 = increases metabolism 2. Calcitonin = promotes bone deposition • Removes Calcium from blood Parathyroid Gland Hormones: 1. Parathyroid Hormone (PTH) = Promotes bone resorption • Increases blood Kidney Adrenal Glands Ovaries Kidney Adrenal Gland Cortex medulla Adrenal Medulla Epinephrine (adrenaline) & Norepinephrine •“Fight or Flight” hormones • Stress Response Adrenal Cortex (Steroid Hormones) Aldosterone: Increases sodium reabsorption by kidneys Cortisol: Gluconeogenesis • Glucose synthesis from noncarbohydrates Sex Hormones: supplement gonads Kidneys Erythropoietin • Stimulates RBC production Pancreas Pancreatic islets (Isets of Langerhans) Alpha Cells Glucagon Beta Cells Insulin Delta Cells Somatostatin Pancreas hormones • Glucagon: Raises blood glucose – Gluconeogenesis – Glycogenolysis • breakdown of glycogen into glucose • Insulin: Lowers blood glucose – Promotes cellular uptake of glucose Thymus Secretes Thymosin: Promotes T-cell maturation • Ovaries – secretes estrogen/progesterone • Testes – secretes testosterone Estrogen, Progesterone, and Testosterone = steroid hormones Left Subclavian vein Thoracic Duct Right Subclavian Vein Right Lymphatic Duct Cervical Lymph nodes Axillary Lymph nodes Abdominal (Mesenteric) Lymph Nodes Inguinal Lymph Nodes Supratrochlear Lymph Nodes Thoracic Lymph Nodes Tonsils Appendix • Thought to serve as a lymphatic organ Thymus gland & Spleen Thymus gland – Development of T lymphocytes Spleen – removes viruses, bacteria, and old RBC from circulation Lymph Node Slide Cortex medulla Nodule • Cortex = Nodules of B-Cell lymphocytes • Medulla = T-Cell Lymphocytes & Macrophages Spleen Red Pulp White Pulp Red Pulp – Composed of red blood cells White Pulp – Composed of white blood cells