Download Supplementary Table 1

Supplementary Table 1. List of common upregulated genes in both HDAC2 mutant
cancer cell lines (RKO and Co115) in comparison with all the four HDAC2 wild-type
cells (SW48, HCT116, HCT15 and LoVo) (Mann-Whitney P<0.01 and average foldchange>2)
Gene accession number
NM_015831.1
AI638420
NM_003916.1
U48437.1
NM_001643.1
NM_030882.1
U34846.1
AV760769
NM_024696.1
NM_022161.1
AF060922.1
AF073483.1
AC004770
AC005034
NM_006848.1
NM_003607.1
AI123527
NM_012110.1
NM_001825.1
NM_000095.1
NM_014325
BF939649
X07618.1
AK027254.1
AA631156
NM_007337.1
AL162056.1
AK026768.1
NM_001960.1
AI613383
AB044548.1
NM_001425.1
NM_004431.1
NM_021922.1
D87858.1
NM_004115.1
NM_004214.3
BE619220
U27329.1
NM_004123.1
M85276
BF222483
NM_000178.1
J03189.1
U43328.1
NM_001553.1
NM_000207.1
Gene Symbol
ACHE
ADD3
AP1S2
APLP1
APOA2
APOL2
AQP4
B4GALT6
BAHCC1
BIRC7
BNIP3L
C11orf68
C11orf9
C2orf3
CCDC85B
CDC42BPA
CEP57
CHIC2
CKMT2
COMP
CORO1C
CORO2B
CYP2D6
DDEF1
DGCR6L
DLEC1
DOPEY1
DPY19L1P1
EEF1D
EEF1D
EIF4EBP1
EMP3
EPHA2
FANCE
FCAR
FGF14
FIBP
FLJ14803
FUT5
GIP
GNLY
GP2
GSS
GZMB
HAPLN1
IGFBP7
INS
GO Biological Process Description
DNA replication
ion transport
intracellular protein transport
cell adhesion
regulation of cytokine production
lipid metabolism
transport
carbohydrate metabolism
--DNA fragmentation during apoptosis
apoptosis
dicarboxylic acid transport
--transcription
--protein amino acid phosphorylation
protein import into nucleus, translocation
--generation of precursor metabolites and energy
cell adhesion
signal transduction
actin cytoskeleton organization and biogenesis
electron transport
regulation of GTPase activity
--negative regulation of cell proliferation
endoplasmic reticulum organization and biogenesis
--protein biosynthesis
protein biosynthesis
regulation of translation
development
transmembrane receptor protein tyrosine kinase signaling pathway
DNA repair
immune response
signal transduction
Cellular comunication
--carbohydrate metabolism
signal transduction
xenobiotic metabolism
--amino acid metabolism
proteolysis
cell adhesion
regulation of cell growth
carbohydrate metabolism /
U24660.1
NM_002246.1
AI373854
AF070587.1
AL050220.1
AA583336
AK023081.1
AF113008.1
AL022313
AK000645.1
AK023285.1
AK023406.1
X98405.1
AF201370.1
AW129021
NM_022564.1
NM_002433.1
AL050328
NM_024848.1
AI239732
NM_005437
Z25434.1
U32500.1
AJ003145.1
AF070547.1
BE397715
AF152516.1
NM_014801.1
U50157.1
U35632.1
gb:AF255793.1
NM_000309.1
AF163473.1
AW009884
X86428
NM_017947.1
NM_005833.1
AF125950.1
AW149379
NM_006867.1
D43968.1
AL035122.1
AB020335.1
D50918.1
NM_012139.1
NM_030974.1
AJ271205.1
BC000563.1
NM_018042.1
AI628464
NM_003082.1
NM_006946.1
AK026820.1
AI718418
KCNJ6
KCNK3
KIAA0415
KIAA1509
KLK13
LOC157562
LOC399818
LOC440992
LOC646756
LOC93432
MACF1
MACF1
MAG
MDM2
MGC87042
MMP16
MOG
MOG
MORN1
NADK
NCOA4
NEK3
NPY2R
OR1F2
PART1
PBX2
PCDHGA9
PCNXL2
PDE4D
PDX-1
PLA2G5
PPOX
PPP2R1B
PPP2R1B
PPP2R4
PTHLH
RABEPK
RAD52
RBM9
RBPMS
RUNX1
SAC
SEL1L
SEPT6
SERGEF
SHARPIN
SLC22A6
SLC6A2
SLFN12
SMAD6
SNAPC1
SPTBN2
ST3GAL1
STCH
ion transport
ion transport
----proteolysis /// proteolysis
--carbohydrate metabolism
protein biosynthesis
--carbohydrate metabolism
cell cycle arrest
cell cycle arrest
cell adhesion
regulation of progression through cell cycle
electron transport
peptidoglycan metabolism
synaptic transmission
synaptic transmission
mRNA metabolism
metabolism
Protein metabolism
protein amino acid phosphorylation
signal transduction
signal transduction
--regulation of transcription
cell adhesion
--signal transduction
regulation of transcription
phospholipid metabolism
electron transport
regulation of progression through cell cycle
regulation of progression through cell cycle
Regulation of cell cycle progression
cell-cell signaling
receptor mediated endocytosis
DNA repair
RNA metabolism
RNA processing
regulation of transcription, DNA-dependent
cAMP biosynthesis
Notch signaling pathway
cytokinesis
signal transduction
--ion transport
neurotransmitter transport
--transcription
regulation of transcription, DNA-dependent
vesicle-mediated transport
protein amino acid glycosylation
---
NM_007029.1
BC001172.1
U28049
AF195820.1
NM_006068.1
NM_023003.1
NM_006291.1
X71923.1
M13231.1
U58766
NM_006472.1
AB019695.1
NM_017481.1
NM_006002.1
AI191771
NM_014150.1
AI375002
AF255793.1
NM_003163.1
NM_018517.1
STMN2
TADA2L
TBX2
TCL6
TLR6
TM6SF1
TNFAIP2
TNXB
TRGC2
TSTA3
TXNIP
TXNRD2
UBQLN3
UCHL3
WNT6
ZCCHC4
ZNF447
-------
intracellular signaling cascade
regulation of progression through cell cycle
transcription
--signal transduction
--angiogenesis
cell adhesion
cellular defense response
protein amino acid glycosylation
keratinocyte differentiation
response to oxygen radical
ubiquitin cycle
ubiquitin-dependent protein catabolism
cell-cell signaling
DNA methylation
regulation of transcription, DNA-dependent
--intracellular protein transport
---