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Name: Genetics Unit - Test Review This test will cover genetics, genetic disorders, and chromosomal disorders. First and foremost, study the notes given in class! Second, look over the two quizzes on genetics. Review the worksheets covering incomplete dominance (spongebob), codominance (blood typing), and sex-linked traits. Just because something is not on the review guide does not mean that it will not be on the test. 1. Describe Mendel’s work. You should know what he worked with and what he discovered. He worked with pea plants. Discovered patterns of inheritance, dominant and recessive traits 2. Solve the following types of genetic problems: 1 trait crosses involving a dominant and a recessive gene. (Tt X Tt) T=Tall t=short T t Genotypic Ratio= TT 25% :Tt 50% :tt 25% T TT Tt Phenotypic Ratio= Tall 75% : short 25% t Tt tt 3. Fill in the missing Dihybrid genotypes: 2 trait crosses involving 2 dominant and 2 recessive genes. (TtGg X TtGg) T=Tall t=Short G=Green g=yellow TG Tg tG tg TG TTGG TTGg TtGG TtGg Tg TTGg TTgg TtGg Ttgg tG TtGG TtGg ttGG ttGg tg TtGg Ttgg ttGg ttgg 4. 1 trait cross that is sex-linked. (in this case, pretend that the disorder is caused by a recessive allele) (XHXh X XHY) XH Xh XH Y XH XH XH Xh XHY Xh Y Describe the possible offspring: 3 “normal” 1 with disorder 1 normal male, 1 male w/ disorder, 1 normal female, 1 carrier female 5. A cross involving 2 genes that are codominant. Cross a Heterozygous A blood type women with a Heterozygous B blood type man. A O List all of the possible genotypes: AB, AO, BO, OO B AB BO List all of the possible phenotypes: O AO OO Type AB Blood, Type A Blood, Type B Blood, Type O Blood 6. Pedigrees: Make sure you put in generation #’s Which individuals are: Male: I- 1, 3; II- 2, 4, 6; III-1 I Affected: III- 1 3 4 II 1 Female: I- 2, 4; II- 1,3,5; III-2 Carriers: I- 2,4; II- 3 2 1 2 3 4 5 6 III 1 2 7. What is a karyotype and identify some of the problems that can be identified by a karyotype. Karyotype- a picture of a person’s chromosomes. Can be used to check for chromosome abnormalities, like Down Syndrome & shows the sex chromosomes. 8. What is nondisjunction? Failure of chromosomes to separate during meiosis. 9. Match the following vocabulary terms: ___ The father of genetics ___ Square diagram used to determine the outcome of a cross ___ A gene that, when present, is always expressed or shown ___ A gene that is only shown when the individual is homozygous ___ Different versions of a gene A. B. C. D. E. F. G. H. I. Dominant Allele Gregor Mendel Punnett Square Genotype Phenotype Recessive Monohybrid Cross Likelihood an event will occur ___ Actual gene make-up or combination of alleles ___ Form of a trait that is observed ___ A genetic cross involving only 1 trait ___ Probability 10. Karyotypes: Answer the following questions: Is this a male or female: Female Normal or abnormal karyotype: Abnormal – missing the second sex-chromosome 11. Incomplete Dominance Punnett Square: Purple Thingamadoodles are created due to incomplete dominance from Red (R) and Blue (B) Thingamadoodles. Using a punnett square show all of the possible offspring from a cross between two Purple Thingamadoodles. R R B B RR RB RB BB Possible Genotypes (with %) Possible Phenotypes (with %) RR RR – 25% RB – 50% BB – 25% Red – 25% Purple – 50% Blue – 25%