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Punnett square. Segregation Assortment Gregor Mendel Blending hypothesis. Particulate theory of heredity Christian Doppler Franz Unger Character Trait True breeding P generation (parental) F1 generation (first filial) F2 generation (second filial) Hybrid Monohybrid Dihybrid Law of Segregation Phenotype Genotype Phenotypic ratio Genotypic ratio 3:1 1:2:1 1:1 Test cross 9:3:3:1 Dominant Recessive Allele Homozygous Heterozygous Law of Independent Assortment Self-pollinate Laws of probability Probability scale Rule of multiplication Rule of addition Trihybrid Spectrum of dominance Complete dominance Codominance Incomplete dominance MN blood-group Intermediate phenotype Dominance/recessiveness relationships Organismal level Biochemical level Molecular level Polydactyly Multiple alleles ABO blood group Universal donor Universal recipient Pleiotropy Epistasis albinism Polygenic inheritance discrete characters quantitative characters Continuous variation Nature versus nurture Norms of reaction for a genotype: Pedigree analysis Cystic fibrosis Tay-Sachs disease Sickle-cell disease heterozygote advantage Consanguinity Achondroplasia Lethal dominant Late-acting lethal dominants Huntington's disease Multifactorial disorders Risk assessment Carrier testing Fetal testing Amniocentesis Chorionic villus sampling (CVS) Ultrasound Fetoscopy Newborn screening Phenylketonuria (PKU) CHAPTER 15 Cytology Chromosome theory of inheritance Drosophila melanogaster Thomas Hunt Morgan Alfred Sturtevant Wild type Mutants Sex-linkage Y-linkage Autosomal-linkage Unlinked genes dihybrid testcross Parental types Recombinants Genetic recombination Frequency of recombination Linkage map Chromosome map Map unit Centimorgan Double crossover Cytogenetic maps Nucleotide sequence maps Heterogametic sex Homogametic sex SRY (sex-determining region of Y) Sex-linked disorders Color blindness Hemophilia. Hemizygous X-inactivation Lyon hypothesis Barr body. Mosaic Maternal X Paternal X DNA methylation Nondisjunction Meiotic nondisjunction: Mitotic nondisjunction: Aneuploidy Trisomy Monosomy Abnormal gene dosage Polyploid Triploidy Tetraploidy Deletion Duplication Translocation Inversion Nonreciprocal crossover Position effects Down syndrome Klinefelter Syndrome Extra Y Triple-X Syndrome or Trisomy X Turner Syndrome Cri du chat syndrome Chronic myelogenous leukemia (CML) Philadelphia chromosome Prader-Willi syndrome Angelman syndrome Genomic imprinting Extranuclear genes Cytoplasmic genes Mitochondrial DNA Plastid DNA