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Fall Semester Honors Final Review Guide Name ____________________________________________ Date _________ Period_______ The Semester Final will cover the following topics: - Scientific Method, Evolution, Cell, Cell Transport, Water, Mitosis, DNA and Protein Synthesis, - About 50% of the test will come from 1st quarter and 50% from 2nd quarter. - Please be sure to review all of your notes, labs and homework assignments. Terms you should know. Scientific Method Qualitative Quantitative Inference Observation Hypothesis Prediction Biology Metabolism Homeostasis Heredity Mutation Cells cell theory prokaryote eukaryote phospholipids lipid bilayer Cell Transport passive transport concentration gradient equilibrium diffusion osmosis hypertonic hypotonic isotonic ion channel carrier protein facilitated diffusion active transport sodium-potassium pump endocytosis exocytosis Water Covalent bond Molecule Ionic bond Proteins Amino acid Enzymes Nucleic acid Mitosis Binary fission Chromosome Somatic cells G1 phase S phase G2 phase Diploid cells Haploid cells Sister chromatid Centromere Chromatin Histones Interphase Prophase Metaphase Anaphase Telophase Cytokinesis DNA Nucleotide Chargaff’s rule Double helix DNA replication Replication fork Helicase DNA polymerase Ligase Deoxyribose RNA & Protein Synthesis protein amino acid uracil transcription translation RNA polymerase messenger RNA codon transfer RNA anticodon ribosomal RNA Genetics Gene Allele Independent assortment (Law of) Segregation (Law of) Genotype Phenotype Homozygous Heterozygous Dominant Recessive Cross Punnett square Test cross Pedigree Linked genes Sex-linked genes Codominance Incomplete dominance Multiple alleles Polygenic inheritance 1 Scientific Method A scientist named Dr. Smartee, wondered why his two favorite fish, Flotsem and Jetsem were not growing at the same rate. Flotsem, a male, was growing at a faster rate than Jetsem, also a male. He bought the fish at the same time and the fish salesman assured him that they were the same age. He thought that maybe one fish was eating all the food during feeding time. The scientist decided to do an experiment. He separated the fish into two different tanks and fed them the same amount of food for two weeks; made sure they had the same amount of light, and kept the solute levels the same. After two weeks he weighed the fish and was amazed by the results. Flotsem’s weight had increased by 1 gram, and Jetsem’s weight increased by 4 grams. 1. What was the independent variable in the above scenario? 2. What was the dependent variable in the above scenario? 3. What are two controlled variables that were identified in the above scenario? 4. What were the results of this scenario? 5. Did the results support Dr. Smartee’s hypothesis? 6. Could Dr. Smartee conclude that Flotsem was stealing Jetsem’s food or is another explanation possible for the results? 7. Graph the Result Cells 8. What molecule in the cell contains hereditary information (instructions for growth and development)? 9. What is a prokaryote? Give an example. 10. What is a eukaryote? Give an example. 11. What are TWO differences between prokaryotes and eukaryotes? 2 12. What is an organelle? 13. What is a biotic factor? Give an example. 14. What is an abiotic factor? Give an example. 15. In the table below list the function of each of the organelles. Organelle 1. Cell membrane Function (what does it do!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!) 2. Cytoplasm 3. Nucleus 4. Nucleolus 5. Mitochondria 6. Ribosomes 7. Endoplasmic Reticulum 8. Golgi Apparatus 9. Lysosomes 10. Cytoskeleton 11. Cilia 12. Cell wall 13. Vacuole 14. Chloroplast 16. What organelles are found only in plant cells? 3 17. Label the cell: Plant, Animal, or Prokaryote. Label all the organelles using numbers is acceptable. Cell type:________________ Cell type:________________ Cell type:________________ 4 Cellular Transport 18. What is homeostasis? What organelle helps maintain homeostasis? 19. What will happen to a cell placed in the following environments? Draw each using X’s as solutes and an arrow representing solution movement. Hypertonic Hypotonic Isotonic 20. Complete the following summary table. Type of solution Where is solute concentration the highest (inside cell or outside cell) Will water move in or out of cell? Will the cell swell, shrink, or stay the same size? Hypertonic Hypotonic Isotonic 21. What are two differences between active transport and passive transport? 22. List and describe the types of passive transport. 23. List and describe the types of active transport. 5 24. What is the difference between osmosis and diffusion? 25. What is the difference between endocytosis and exocytosis? Water Properties of Water 26. Complete the chart: Properties of Definition of Property Water Cause of Property (Hydrogen bonding or polarity) Which Olympic Event Demonstrated the Property Surface Tension Cohesion Adhesion Capillary Action Polar vs. Non polar Specific Heat 27. Explain hydrogen bonding. 28. Draw three water molecules that are bonded together. Show polarity, hydrogen bonds, and covalent bonds within your drawing. 29. Describe in words water’s polarity. 6 Mitosis 30. Draw the 4 stages of mitosis (label them while you’re at it… ). 31. List the phases of the cell cycle (there are 5 phases; mitosis itself is ONE of them). 32. In which phase of the cell cycle do cells spend most of their time? 33. What are the functions of mitosis? 34. Is interphase a stage of mitosis? What happens during interphase? 35. How many cells are produced during mitosis? How many chromosomes does each contain? Molecular Genetics (DNA, RNA, proteins) 36. What does DNA stand for? 37. What is a gene? 38. What do genes code for? 39. The four nitrogen bases of DNA are (spelled out): 7 40. Base-paring: in DNA a. ___________pairs with____________, and ___________ pairs with _____________ 41. Chargaff! If the genome of an organism consists of 32%guanine, what is the concentration of the other bases? a. G=_32%__, C=_________, A=_________, T=_________ 42. Compare and contrast DNA, genes, and chromosomes. 43. What is a nucleotide? What are the 3 components to a nucleotide? 44. Describe the structure of DNA. Draw it. 45. Diagram the process of DNA replication. Include the replication fork, helicase, ligase, DNA polymerase, and 3’and 5’ on both old and new strands. 46. Create the complementary DNA sequence: 5’ A-T-C-G-A-A-T-T-G-C-A-T-A-T-T-A-C 3’ 47. Why is DNA replication important? 48. RNA base Pairing: a. ___________pairs with____________, and ___________ pairs with _____________ 8 49. RNA uses the nitrogen base _____________________ instead of __________________. 50. Diagram the process of transcription. 51. Why is transcription important? Why is it beneficial for the DNA? Be detailed. 52. Create the mRNA from the following DNA: 3’ T-A-C-C-G-A-A-T-T-A-C-T-A-G-T-A-C-G 5’ 53. What are the 3 types of RNA found in the cell? What are their functions? 54. What occurs during translation? 55. Diagram the process of translation. 9 56. What types of RNA are involved with translation? 57. What types of RNA are involved with transcription? 58. What are the building blocks of protein? 59. If an mRNA had 12 codons, how many amino acids would it code for? 60. Where does transcription and translation occur in the cell? (ID both) 61. The mRNA codon AUG codes for the amino acid _______________ 62. The mRNA codon CCA codes for the amino acid ________________ 63. Find the entire amino acid sequence for the following DNA sequence. (transcribe then translate) 3’ T-A-C-C-G-A-T-T-A-C-A-C-G-A-C-T-G-C-A-G-G 5’ 64. What is a mutation? 65. What are the three major effects mutations can have? 66. List types of a. DNA mutations b. Gene mutations c. Chromosomal mutations. 10 Genetics 67. Who is the father of genetics? What did he study? 68. Describe his experiments and the two major laws of heredity he discovered. 69. Compare and contrast DNA, gene, & allele. Give an example. 70. What is a dominant and recessive genotype? 71. What do the terms homozygous and heterozygous refer to? Give examples. 72. What is the predicted genotypic and phenotypic ratios of two heterozygous parents for a completely dominant trait? 73. Predict the outcome of offspring between homozygous and/or heterozygous parents for completely dominant traits. 74. Predict the outcome of offspring of parents with various blood types. a. AO x BO b. AA x BO c. OO x AB 75. What is incomplete dominance? Give an example or explain a model trait. 76. Cross two heterozygous (pink) snapdragons. What are the different genotypes and the corresponding phenotypes that result? 77. What is co-dominance? Give an example or explain a model trait. 78. Cross two heterozygotes (AB) for blood type. What are the different genotypes and the corresponding phenotypes? 79. Can a person pass on a trait, even they don’t show or have it themselves? HOW? 80. What does a dihybrid cross predict? How can you figure out the allele combinations they will pass on? 11 81. Which chromosome are most sex-linked traits carried on? 82. What are all possible genotypes of parents when predicting sex-linked traits? 83. The pedigree to the right shows the presence or absence of the albinism trait in several generations of a family. K L M N Analysis 84. Determine whether the albinism trait is dominant or recessive. Explain your reasoning. 85. Determine the genotypes for females A & B. 86. Based upon your conclusion to Question 1 & 2, determine what the genotype is for the parents of Female A and Female B. 87. Determine the genotypes as many of the family members of this pedigree as possible and label each genotype in the pedigree above. Use the following designations in and place the numbers of each on the lines below: AA = Homozygous dominant. _________________________________________________ Aa = Heterozygous: _________________________________________________________ aa = Homozygous recessive: __________________________________________________ ?? = Not enough information to conclude: 88. Is this trait sex-linked on the x chromosome? YES or NO 89. Explain why or why not. 12