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15 Week CCA Tuesday, December 6 Mutations Gene Mutations 1.) What is a point mutation? Give an example. 2.) Create a substitution gene mutation in the following DNA Strand, Original: TACGGT Substitution: _________ 3.) What is a frameshift mutation? Give 2 examples. 4.) Create a deletion gene mutation in the following DNA strand: Original: TACGGT Deletion: ___________ 5.) Create a insertion gene mutation in the following DNA strand: Original: TACGGT Insertion: ___________ General Mutation Questions 6.) Can an organism pass on a mutation to its offspring? If yes, explain how this is possible. 7.) A change in a single base pair in DNA is least likely to be observed if the change occurs in _______________________________________________________. 8. What is haploid and diploid ? If an organism’s diploid number is 40, its haploid number is_____. Genetics 9. ) In guinea pigs, black coat color is dominant over tan coat color. Show a cross between a tan guinea pig and a heterozygous black guinea pig. Answer the following questions below about their offspring. F1 phenotypes: _____________________________ F1 genotype: _______________________________ F1 phenotypic percentages: ___________________ F1 genotypic percentages: ____________________ F1 phenotypic ratio: _________________________ F1 genotypic ratio: _________________________ 10..) In pea plants, yellow (Y) pea color is dominant over green (y) pea color. And round (R) peas are dominant over wrinkled (r) peas. Show a cross between a heterozygous yellow, heterozygous round pea plant with a heterozygous yellow, heterozygous round pea plant. 11. If a person possess a gene for cancer, does that mean the person will definitely develop this type of cancer? 12.) Every cell in your body contains the same genetic information. Many of the cells in our body have a specialized function. For example, your muscle cells are going to have a different function from your skin cells. Explain how this is possible given your knowledge about genes. 13.) What is incomplete dominance? What is co-dominance? 14.) In northeast Kansas there is a creature know as a wildcat. It comes in three fur colors: red, white and pink. A (rr) individual is red, a (ww) individual is white, and a (rw) individual is pink. What would be the genotypes and phenotypes of the offspring if a red fur wildcat crossed with a white fur wildcat? Is this an example of incomplete dominance or codominance? ___________________ Parents’ genotype: __________________ Offspring Phenotypic ratios: _____________ 15.) In northeast Kansas there is a creature know as a wildcat. It comes in three fur colors: red, white and pink. A (rr) individual is red, a (ww) individual is white, and a (rw) individual is pink. What would be the genotypes and phenotypes of the offspring if a pink fur wildcat crossed with a pink fur wildcat? Parents’ genotype: __________________ Offspring Phenotypic ratios: _____________ Sex-linked Traits 16. What is the genotype of a female________? The sex chromosome that a human female can give her children are_______________? 17. What is the genotype of a male__________? The sex chromosome that a human male can give her children are_______________? 18. Who determines the sex of the child? Explain why. Single-Crosses 19. Freckles (S) are dominant over no freckles (s). Patty is homozygous dominant for freckles, while Charlie is homozygous for no freckles. Draw a Punnett square predicting the probability if their children will have freckles. 20. In guinea pigs, the allele for rough coat (R) is dominant to the allele for smooth coat (r). If a male guinea pig that is heterozygous for rough coat is mated with a female with smooth coat, what are the genotypes and phenotypes of the offspring? Sex-linked Inheritance 21. Eye color in Drosophila is a sex-linked trait carried on the X chromosome. The gene for red eyes is dominant over the gene for white eyes. Draw a punnett square showing the cross between a heterozygous red eyed female with a white-eyed male. 22. Colorblindness is a sex-linked trait carried on the X chromosome. Show the cross between a colorblind male and a normal female. What is the possibility of their children having colorblindness? Blood Types 23. Blood type is an example of a trait that has multiple alleles resulting in more than two outcomes for blood type. Cross a male with homozygous type A blood with a female that is heterozygous for type B blood. 24. . Using the chart below, which blood type is the universal donor ( all blood types can receive this type of blood)? \ 25. Using the above pedigree, which type of trait is being inherited, sex-linked or dominant? Explain why?