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1. Who is the Father of Genetics Gregor Mendel 2.Law of Dominance Dominant allele will hide/mask the recessive allele in the heterozygous state (F1 generation) During gamete formation the two alleles for a trait become separated into different gametes During gamete formation, genes for traits are inherited separately, independent from one another 3.Law of Segregation 4.Law of Independent Assortment 5.Allele 6. Having two identical alleles Different forms of a gene for a trait (T= tall, t= short) Homozygous 7. Having two different alleles Heterozygous/Hybrid 8. Genotype 9. Phenotype Genetic makeup, combination of genes Physical appearance (words) 10. Genotypic ratio of a cross between two heterozygous organisms 11. Dominant 1 Homozygous Dominant 2 Heterozygous 1 Homozygous Recessive Allele that hides or masks another allele in the heterozygous state Allele that is hidden or masked in the heterozygous state (only expressed if homozygous recessive) Test Cross – used to determine if the dominant organism is homozygous or heterozygous 12. Recessive 13. Cross performed between a recessive organism and an organism showing the dominant trait 14.Pure bred Mendel’s P generation -pure for 2 contrasting traits 15.F1 generation Results/offspring from P generation cross 16. Cross involving one pair of contrasting traits 17. Cross involving two pairs of contrasting traits 18. Possible gametes of GGTt 19. GgTt X GgTt Monohybrid 20. Incomplete Dominance Heterozygote shows an intermediate/blend of phenotypes Dihybrid GT, Gt 9 GT, 3 Gt, 3 gT, 1 gt 21. Both alleles are equally expressed – ex. coat color in cattle 22. Having more than 2 alleles that can determine a phenotype 23.Give an example of 22. between the two parental types Codominance – produces 3 different phenotypes Multiple Alleles Human Blood Groups 24. Genotype for type O blood OO 25. Universal Recipient AB 26. Possible genotypes for type A blood 27. Hemophilia 28. Disorders that occur more frequently in males 29. Phenotype XHXh 30. Genotype for a male who is a hemophiliac 31. Two alleles located on the same chromosome 32. Chromosome Map and what are they based on? 33. Recombination Frequency AA, AO 34. Determine the relative positions of the following three genes on a chromosome: A and D are rarely separated, A and C are separated frequently. 35. Genotype for a male Disorder in which blood does not clot properly (sex-linked) Sex Linked Disorders Normal female, but a carrier for hemophilia XhY Linked Map of genes on a chromosome based on frequency of recombination Frequency of crossing over, the further apart the genes are from one another, the higher the rate of crossing over A, D, C XY 36. Genotype for a female XX 37. Determines the sex of the child 38. How can linked genes be Male (bc he has X sperm and Y sperm, females only have X eggs) Crossing over during meiosis separated 39. Number of chromosomes in a human sperm or egg cell 40. Polygenic Traits 23 Also called multiple genes – more that one pair of genes determine a trait (bell curve, many phenotypes) Practice Problems: For all problems state genotypic and phenotypic ratios 1. Heterozygous tall x heterozygous tall Tt x Tt = G1 TT, 2 Tt, 1 tt P3 tall, 1 short 2. Homozygous tall X short TT x tt = G4 Tt, P all tall 3. A man with type O blood and a woman with type AB blood. OO x AB = G 2 AO, 2 BO, P2 A, 2 B 4. A woman with colorblind parents marries a man who is also colorblind. All colorblind 5. Homozygous black homozygous running mouse x a waltzing brown mouse BBRR x bbrr = G BbRr P all running black 6. A white flower crossed with a red flower produces a pink flower. How is the trait inherited? Incomplete Dominance WW x RR = G RW P pink 7. Cross a pink flower from above with a red flower. RW x RR = G 2 RW 2 RR, P 2 Pink, 2 Red