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MCB 135K Discussion March 10/11, 2004 1. Vision a. The Eye’s Optical Components i. Cornea ii. The Lens iii. Decline in Accomodation and Development of Presbyopia iv. Iris and Senile Miosis v. Anterior Chamber and Virteous Humor vi. Aging Changes in the Retina b. Aging of Visual Functions i. Eye Movements, Visual Thresholds, Critical Flicker Frequency, Field, Spatial Vision, Color Perception, Changes in Central Visual Pathways c. Aging and Eye Diseases i. Cataract ii. Glaucoma iii. Age-Related Macular Degeneration 2. Aging of the Cardiovascular System a. Atherosclerosis i. Definition ii. Characteristics iii. Pathogenesis 1. Myocardial Infarction 2. Stroke 3. Aneurysm b. Function of Cardiovascular System c. Components of Cardiovascular System d. Affects of Atherosclerosis on the Arteries e. Progressiveness f. Atherogenesis i. Fatty Streak Formation ii. Fibrous Plaque Formation iii. Unstable Plaque Formation g. Characteristics of Atherosclerotic Lesions h. Localized Factors i. Significance of age changes j. Theories of Atherosclerosis k. Angina Pector l. Risk Factors of Coronary Heart Disease m. Primary Prevention n. Types of Treatment i. Non Drug Therapy ii. Nutrition and Habit Modification iii. Medical Treatment 3. Questions: a. Describe the changes that occur in the ocular structure associated with normal aging b. Describe the changes that occur in visual function associated with normal aging c. What are the recommendations to assist our visual system in aging well d. What is the difference between arteriosclerosis and atherosclerosis e. What are the characteristics associated with atherosclerosis f. Describe the normal pathogenesis of atherosclerosis g. What are the disease implications of advanced atherosclerosis h. Describe the components of the cardiovascular system and what the major functions of this system are i. What is meant by the “progressiveness of atherosclerosis” j. Describe the process of atherogenesis k. What is the significance of age changes in the vascular endothelium (review table 16-2, pg 293) l. Pick two of the theories of atherosclerosis and defend their role (page 299) m. What are the major risk factors in coronary heart disease n. What types of treatment exist for coronary heart disease