Download Mod2-Assignment

Survey
yes no Was this document useful for you?
   Thank you for your participation!

* Your assessment is very important for improving the work of artificial intelligence, which forms the content of this project

Document related concepts
no text concepts found
Transcript 
MODULE 2: DOMAIN STRUCTURE OF EUKARYOTIC TRANSCRIPTION
FACTORS
Discuss:
Common DNA binding motifs of eukaryotic transcriptional activators
v-erb-A and c-erbA
Thyroid hormone receptor – co-repressor interactions
Activation of transcription of cAMP-responsive genes by cyclicAMP
Functional domains of eukaryotic transcriptional activators
Define the function of the following domains:
a) zinc finger
b) helix-turn –helix
c) leucine zipper
d) acidic activation domain
What is the functional significance of RNA Polymerase carboxy terminal domain (CTD)?
Name the general transcription factor which phosphorylates RNA polymerase II CTD
Distinguish between RNA polymerase II A and RNA Polymerase II O.
Related documents