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Transcript 
1
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Igfbp4, Lgals3bp, Xdh, Cd248, Fads2, Ifit1, Ptgis, Col16a1, Hspg2, Isg15, Cyp51, Mt2, Cdh3,
Slc7a5, Crabp1, Loxl1.
oxidation reduction (3), oxidoreductase activity, acting on the CH-N... (1) GO:0016641, xanthine
oxidase activity (1), xanthine dehydrogenase activity (1), response to virus (1), xanthine catabolic
process (1), regulation of cell growth (1), cell adhesion (3).
Peg3: nucleus, transcription factor activity, zinc ion binding, regulation of transcription,
DNA-dependent, transcription.
Htatsf1: nucleus, nucleotide binding, RNA binding, regulation of transcription, transcription.
Ikbkg: nucleus, metal ion binding, B cell homeostasis, regulation of transcription, transcription.
Irf7: cytoplasm, nucleus, protein binding, transcription factor activity, immunoglobulin mediated
immune response, regulation of transcription, DNA-dependent, response to virus, transcription,
type I interferon biosynthetic process.
GO:0001558
P:regulation of cell growth|4|1|9.41640086206896|0.0625
GO:0007155
P:cell adhesion|23|3|12.2385644677661|0.1875
GO:0007595
P:lactation|3|1|13.1703735632184|0.0625
GO:0055114
P:oxidation reduction|42|3|4.63671798029557|0.1875
GO:0030856
P:regulation of epithelial cell differentiation|1|1|43.3345689655172|0.0625
GO:0009115
P:xanthine catabolic process|1|1|43.3345689655172|0.0625
GO:0022900
P:electron transport chain|4|1|9.41640086206896|0.0625
GO:0006633
P:fatty acid biosynthetic process|4|1|9.41640086206896|0.0625
GO:0006810
P:transport|10|2|14.3456896551724|0.125
GO:0001516
P:prostaglandin biosynthetic process|2|1|20.7003879310345|0.0625
GO:0001525
P:angiogenesis|8|1|3.84061422413793|0.0625
GO:0032020
P:ISG15-protein conjugation|2|1|20.7003879310345|0.0625
GO:0019941
P:modification-dependent protein catabolic pr...|1|1|43.3345689655172|0.0625
GO:0009615
P:response to virus|9|1|3.23334291187739|0.0625
GO:0006695
P:cholesterol biosynthetic process|6|1|5.68449712643678|0.0625
GO:0007156
P:homophilic cell adhesion|8|1|3.84061422413793|0.0625
GO:0030154
P:cell differentiation|20|1|0.707004310344828|0.0625
GO:0007399
P:nervous system development|10|1|2.75193965517241|0.0625
GO:0015804
P:neutral amino acid transport|1|1|43.3345689655172|0.0625
GO:0055085
P:transmembrane transport|18|1|0.914602490421456|0.0625
GO:0005520
F:insulin-like growth factor binding|2|1|20.7003879310345|0.0625
GO:0005515
F:protein binding|105|3|0.201169950738916|0.1875
GO:0005044
F:scavenger receptor activity|5|1|7.17284482758621|0.0625
GO:0051537
F:2 iron, 2 sulfur cluster binding|1|1|43.3345689655172|0.0625
GO:0009055
F:electron carrier activity|6|3|62.1011637931034|0.1875
GO:0050660
F:FAD binding|6|1|5.68449712643678|0.0625
GO:0005506
F:iron ion binding|3|1|13.1703735632184|0.0625
GO:0030151
F:molybdenum ion binding|1|1|43.3345689655172|0.0625
GO:0043546
F:molybdopterin cofactor binding|1|1|43.3345689655172|0.0625
GO:0004854
F:xanthine dehydrogenase activity|1|1|43.3345689655172|0.0625
GO:0004855
F:xanthine oxidase activity|1|1|43.3345689655172|0.0625
GO:0005509
F:calcium ion binding|39|2|1.50812555260831|0.125
GO:0005529
F:sugar binding|7|1|4.62769704433498|0.0625
GO:0020037
F:heme binding|7|3|52.4134113300493|0.1875
GO:0005488
F:binding|13|1|1.77247347480106|0.0625
GO:0004497
F:monooxygenase activity|1|1|43.3345689655172|0.0625
GO:0008116
F:prostaglandin-I synthase activity|1|1|43.3345689655172|0.0625
GO:0005178
F:integrin binding|5|1|7.17284482758621|0.0625
GO:0005198
F:structural molecule activity|6|1|5.68449712643678|0.0625
GO:0008022
F:protein C-terminus binding|4|1|9.41640086206896|0.0625
GO:0031386
F:protein tag|1|1|43.3345689655172|0.0625
GO:0008398
F:sterol 14-demethylase activity|1|1|43.3345689655172|0.0625
GO:0042605
F:peptide antigen binding|3|1|13.1703735632184|0.0625
GO:0016918
F:retinal binding|1|1|43.3345689655172|0.0625
GO:0019841
F:retinol binding|1|1|43.3345689655172|0.0625
GO:0005215
F:transporter activity|5|1|7.17284482758621|0.0625
GO:0005507
F:copper ion binding|2|1|20.7003879310345|0.0625
GO:0016641
F:oxidoreductase activity, acting on the CH-N...|1|1|43.3345689655172|0.0625
GO:0005615
C:extracellular space|27|2|3.30882503192848|0.125
GO:0016020
C:membrane|21|1|0.621186371100164|0.0625
GO:0005578
C:proteinaceous extracellular matrix|15|2|8.41436781609196|0.125
GO:0005576
C:extracellular region|45|2|1.02088122605364|0.125
GO:0005777
C:peroxisome|4|1|9.41640086206896|0.0625
GO:0005737
C:cytoplasm|100|3|0.285021551724138|0.1875
GO:0016021
C:integral to membrane|175|6|1.18349753694581|0.375
GO:0005789
C:endoplasmic reticulum membrane|26|3|10.2588892572944|0.1875
GO:0005604
C:basement membrane|6|1|5.68449712643678|0.0625
GO:0005792
C:microsome|11|1|2.36207680250784|0.0625
GO:0005913
C:cell-cell adherens junction|2|1|20.7003879310345|0.0625
GO:0016324
C:apical plasma membrane|5|1|7.17284482758621|0.0625
GO:0005829
C:cytosol|24|1|0.417676005747126|0.0625
3
0.7469
41
Tmem183a, Tor3a, Mndal, Zkscan17, Myo1d, Naglu, Plekhg3, Irx1, Irf9, Enpp2, Ddx17, Dtx3l,
Parp9, Msln, H2-K1, Zbtb12, Nfya, Zfp521, D0H4S114, 0610010O12Rik, Synpo, Rab3il1,
Aldh1a1, Phyhd1, Pdk1, Sulf2, Znfx1, Col11a1, Gbp2, Slc6a9, Mfap2, Gpr153, Agrn, Spon2,
2900026A02Rik, Mmab, Wbscr17, Parp12, Irf7, Smpd3, Plxna3.
cell adhesion (2), oxidation reduction (2), response to virus (1), metabolic process (2), glucose
metabolic process (1), zinc ion binding (5), response to stress (1), oxidoreductase activity, acting
on single d... (1) GO:0016702.
Peg3: nucleus, transcription factor activity, zinc ion binding, regulation of transcription,
DNA-dependent, transcription.
Htatsf1: nucleus, nucleotide binding, RNA binding, regulation of transcription, transcription.
Ikbkg: nucleus, metal ion binding, B cell homeostasis, regulation of transcription, transcription.
Irf7: cytoplasm, nucleus, protein binding, transcription factor activity, immunoglobulin mediated
immune response, regulation of transcription, DNA-dependent, response to virus, transcription,
type I interferon biosynthetic process.
GO:0007155
P:cell adhesion|23|2|0.375981277653856|0.0487804878048781
GO:0055114
P:oxidation reduction|42|2|0.0592606832472265|0.0487804878048781
GO:0009615
P:response to virus|9|1|0.473735164937856|0.024390243902439
GO:0007399
P:nervous system development|10|1|0.33380992430614|0.024390243902439
GO:0005515
F:protein binding|105|6|0.000648804517601824|0.146341463414634
GO:0005044
F:scavenger receptor activity|5|1|1.81934398654331|0.024390243902439
GO:0005509
F:calcium ion binding|39|1|0.658925621616959|0.024390243902439
GO:0005529
F:sugar binding|7|1|0.921994473146702|0.024390243902439
GO:0042605
F:peptide antigen binding|3|1|4.06396411550322|0.024390243902439
GO:0005578
C:proteinaceous extracellular matrix|15|1|0.0271376506868517|0.024390243902439
GO:0005576
C:extracellular region|45|2|0.116643304364078|0.0487804878048781
GO:0005737
C:cytoplasm|100|5|0.0759041211101766|0.121951219512195
GO:0016021
C:integral to membrane|175|6|1.53418238615884|0.146341463414634
GO:0008152
P:metabolic process|9|2|4.36804410802729|0.0487804878048781
GO:0006355
P:regulation of transcription,
DNA-dependent|30|5|6.43232408186151|0.121951219512195
GO:0006350
P:transcription|67|5|0.387072543087757|0.121951219512195
GO:0045449
P:regulation of transcription|19|1|0.00516311805586297|0.024390243902439
GO:0045351
P:type I interferon biosynthetic process|4|2|13.90913372582|0.0487804878048781
GO:0016042
P:lipid catabolic process|5|1|1.81934398654331|0.024390243902439
GO:0001656
P:metanephros development|2|1|6.95456686291001|0.024390243902439
GO:0007049
P:cell cycle|9|1|0.473735164937856|0.024390243902439
GO:0007165
P:signal transduction|35|5|4.60997236573351|0.121951219512195
GO:0007275
P:multicellular organismal development|14|2|1.8439889462934|0.0487804878048781
GO:0007186
P:G-protein coupled receptor protein
signalin...|8|1|0.662779646761985|0.024390243902439
GO:0006006
P:glucose metabolic process|3|1|4.06396411550322|0.024390243902439
GO:0030199
P:collagen fibril organization|2|1|6.95456686291001|0.024390243902439
GO:0004065
F:arylsulfatase activity|3|1|4.06396411550322|0.024390243902439
GO:0003700
F:transcription factor activity|32|6|9.70294785534062|0.146341463414634
GO:0003677
F:DNA binding|30|1|0.285982618446874|0.024390243902439
GO:0005525
F:GTP binding|22|1|0.0479073323648597|0.024390243902439
GO:0008270
F:zinc ion binding|80|5|0.0500525651808242|0.121951219512195
GO:0046872
F:metal ion binding|27|5|7.89997694919478|0.121951219512195
GO:0005524
F:ATP binding|78|5|0.0786392357292274|0.121951219512195
GO:0046982
F:protein heterodimerization activity|8|1|0.662779646761985|0.024390243902439
GO:0042803
F:protein homodimerization activity|10|1|0.33380992430614|0.024390243902439
GO:0043565
F:sequence-specific DNA binding|15|1|0.0271376506868517|0.024390243902439
GO:0003924
F:GTPase activity|12|1|0.15219792542753|0.024390243902439
GO:0003723
F:RNA binding|20|1|0.0151808242220353|0.024390243902439
GO:0005201
F:extracellular matrix structural
constituent|9|1|0.473735164937856|0.024390243902439
GO:0009986
C:cell surface|4|1|2.6469386038688|0.024390243902439
GO:0005783
C:endoplasmic reticulum|12|2|2.5729296327446|0.0487804878048781
GO:0005795
C:Golgi stack|3|1|4.06396411550322|0.024390243902439
GO:0005634
C:nucleus|118|11|2.80559621388148|0.268292682926829
GO:0005739
C:mitochondrion|27|1|0.181819767622964|0.024390243902439
GO:0009897
C:external side of plasma membrane|4|1|2.6469386038688|0.024390243902439
GO:0005886
C:plasma membrane|62|4|0.0695428524919287|0.0975609756097561
GO:0000139
C:Golgi membrane|13|2|2.17607297664489|0.0487804878048781
GO:0005759
C:mitochondrial matrix|2|1|6.95456686291001|0.024390243902439
GO:0016459
GO:0051085
GO:0030308
GO:0035023
C:myosin complex|4|1|2.6469386038688|0.024390243902439
P:chaperone mediated protein folding
requirin...|2|1|6.95456686291001|0.024390243902439
P:negative regulation of cell growth|2|1|6.95456686291001|0.024390243902439
P:regulation of Rho protein signal
transduction|2|1|6.95456686291001|0.024390243902439
GO:0006935
P:chemotaxis|5|1|1.81934398654331|0.024390243902439
GO:0006955
P:immune response|18|3|3.85939444911691|0.0731707317073171
GO:0006396
P:RNA processing|1|1|15.7394785534062|0.024390243902439
GO:0010390
P:histone monoubiquitination|1|1|15.7394785534062|0.024390243902439
GO:0006974
P:response to DNA damage stimulus|4|1|2.6469386038688|0.024390243902439
GO:0002485
GO:0042590
P:antigen processing and presentation of
endo...|1|1|15.7394785534062|0.024390243902439
P:antigen processing and presentation of
exog...|2|1|6.95456686291001|0.024390243902439
GO:0042742
P:defense response to bacterium|1|1|15.7394785534062|0.024390243902439
GO:0001916
P:positive regulation of T cell mediated
cyto...|2|1|6.95456686291001|0.024390243902439
GO:0006366
GO:0030865
GO:0032233
GO:0051492
GO:0007166
P:transcription from RNA polymerase II
promoter|1|1|15.7394785534062|0.024390243902439
P:cortical cytoskeleton organization|1|1|15.7394785534062|0.024390243902439
P:positive regulation of actin filament
bundl...|1|1|15.7394785534062|0.024390243902439
P:regulation of stress fiber assembly|1|1|15.7394785534062|0.024390243902439
P:cell surface receptor linked signaling
pathway|3|1|4.06396411550322|0.024390243902439
GO:0018106
P:peptidyl-histidine phosphorylation|1|1|15.7394785534062|0.024390243902439
GO:0001502
P:cartilage condensation|3|1|4.06396411550322|0.024390243902439
GO:0002063
P:chondrocyte development|1|1|15.7394785534062|0.024390243902439
GO:0048704
P:embryonic skeletal system
morphogenesis|1|1|15.7394785534062|0.024390243902439
GO:0042472
P:inner ear morphogenesis|3|1|4.06396411550322|0.024390243902439
GO:0006029
P:proteoglycan metabolic process|2|1|6.95456686291001|0.024390243902439
GO:0055010
P:ventricular cardiac muscle tissue
morphogen...|1|1|15.7394785534062|0.024390243902439
GO:0015816
P:glycine transport|1|1|15.7394785534062|0.024390243902439
GO:0006836
P:neurotransmitter transport|2|1|6.95456686291001|0.024390243902439
GO:0045162
GO:0007213
P:clustering of voltage-gated sodium
channels|1|1|15.7394785534062|0.024390243902439
P:muscarinic acetylcholine receptor
signaling...|1|1|15.7394785534062|0.024390243902439
GO:0043113
P:receptor clustering|1|1|15.7394785534062|0.024390243902439
GO:0045087
P:innate immune response|13|1|0.095397554506049|0.024390243902439
GO:0009236
P:cobalamin biosynthetic process|1|1|15.7394785534062|0.024390243902439
GO:0016064
P:immunoglobulin mediated immune
response|1|1|15.7394785534062|0.024390243902439
GO:0030072
P:peptide hormone secretion|1|1|15.7394785534062|0.024390243902439
GO:0006950
P:response to stress|2|1|6.95456686291001|0.024390243902439
GO:0006684
P:sphingomyelin metabolic process|1|1|15.7394785534062|0.024390243902439
GO:0003855
F:3-dehydroquinate dehydratase activity|1|1|15.7394785534062|0.024390243902439
GO:0003779
F:actin binding|12|2|2.5729296327446|0.0487804878048781
GO:0030898
F:actin-dependent ATPase activity|1|1|15.7394785534062|0.024390243902439
GO:0005516
F:calmodulin binding|10|1|0.33380992430614|0.024390243902439
GO:0000146
F:microfilament motor activity|1|1|15.7394785534062|0.024390243902439
GO:0004561
F:alpha-N-acetylglucosaminidase activity|1|1|15.7394785534062|0.024390243902439
GO:0005089
GO:0047391
F:Rho guanyl-nucleotide exchange factor
activity|1|1|15.7394785534062|0.024390243902439
F:alkylglycerophosphoethanolamine
phosphodies...|2|1|6.95456686291001|0.024390243902439
GO:0003676
F:nucleic acid binding|8|2|5.2938772077376|0.0487804878048781
GO:0030247
F:polysaccharide binding|2|1|6.95456686291001|0.024390243902439
GO:0008026
F:ATP-dependent helicase activity|6|1|1.2864648163723|0.024390243902439
GO:0003724
F:RNA helicase activity|1|1|15.7394785534062|0.024390243902439
GO:0008186
F:RNA-dependent ATPase activity|1|1|15.7394785534062|0.024390243902439
GO:0042393
F:histone binding|2|1|6.95456686291001|0.024390243902439
GO:0004842
F:ubiquitin-protein ligase activity|4|1|2.6469386038688|0.024390243902439
GO:0003950
F:NAD+ ADP-ribosyltransferase activity|6|2|8.12792823100645|0.0487804878048781
GO:0001758
F:retinal dehydrogenase activity|1|1|15.7394785534062|0.024390243902439
GO:0016702
GO:0032403
GO:0004740
GO:0000155
GO:0015187
GO:0005328
F:oxidoreductase activity, acting on single
d...|3|1|4.06396411550322|0.024390243902439
F:protein complex binding|2|1|6.95456686291001|0.024390243902439
F:pyruvate dehydrogenase
(acetyl-transferring...|1|1|15.7394785534062|0.024390243902439
F:two-component sensor activity|2|1|6.95456686291001|0.024390243902439
F:glycine transmembrane transporter
activity|1|1|15.7394785534062|0.024390243902439
F:neurotransmitter:sodium symporter
activity|2|1|6.95456686291001|0.024390243902439
GO:0005283
F:sodium:amino acid symporter activity|1|1|15.7394785534062|0.024390243902439
GO:0004930
F:G-protein coupled receptor activity|9|1|0.473735164937856|0.024390243902439
GO:0043236
F:laminin binding|1|1|15.7394785534062|0.024390243902439
GO:0005200
F:structural constituent of cytoskeleton|2|1|6.95456686291001|0.024390243902439
GO:0005102
F:receptor binding|8|1|0.662779646761985|0.024390243902439
GO:0008817
GO:0004653
F:cob(I)yrinic acid a,c-diamide
adenosyltrans...|1|1|15.7394785534062|0.024390243902439
F:polypeptide
N-acetylgalactosaminyltransfera...|1|1|15.7394785534062|0.024390243902439
GO:0004767
F:sphingomyelin phosphodiesterase activity|1|1|15.7394785534062|0.024390243902439
GO:0004888
F:transmembrane receptor activity|2|1|6.95456686291001|0.024390243902439
GO:0030673
C:axolemma|1|1|15.7394785534062|0.024390243902439
GO:0005790
C:smooth endoplasmic reticulum|1|1|15.7394785534062|0.024390243902439
GO:0005764
C:lysosome|5|1|1.81934398654331|0.024390243902439
GO:0005622
C:intracellular|14|2|1.8439889462934|0.0487804878048781
GO:0031225
C:anchored to membrane|4|1|2.6469386038688|0.024390243902439
GO:0005794
C:Golgi apparatus|7|1|0.921994473146702|0.024390243902439
GO:0042612
C:MHC class I protein complex|4|1|2.6469386038688|0.024390243902439
GO:0016602
C:CCAAT-binding factor complex|1|1|15.7394785534062|0.024390243902439
GO:0015629
C:actin cytoskeleton|2|1|6.95456686291001|0.024390243902439
GO:0043197
C:dendritic spine|2|1|6.95456686291001|0.024390243902439
GO:0043204
C:perikaryon|2|1|6.95456686291001|0.024390243902439
GO:0014069
C:postsynaptic density|1|1|15.7394785534062|0.024390243902439
GO:0045211
C:postsynaptic membrane|3|1|4.06396411550322|0.024390243902439
GO:0001725
C:stress fiber|3|1|4.06396411550322|0.024390243902439
GO:0005923
C:tight junction|6|1|1.2864648163723|0.024390243902439
GO:0045254
C:pyruvate dehydrogenase complex|1|1|15.7394785534062|0.024390243902439
GO:0005581
C:collagen|1|1|15.7394785534062|0.024390243902439
GO:0005887
C:integral to plasma membrane|12|1|0.15219792542753|0.024390243902439
GO:0001527
C:microfibril|3|1|4.06396411550322|0.024390243902439
GO:0005605
C:basal lamina|1|1|15.7394785534062|0.024390243902439
GO:0000137
C:Golgi cis cisterna|1|1|15.7394785534062|0.024390243902439
5
0.6543
24
Pla2g4a, Cd24a, Kitl, Igfbp3, Rrm2, Gadd45g, Oxr1, Atad2, Slc48a1, Srxn1, Trim59, Gclm,
Ppap2b, Fam54b, Serpine1, Hsph1, Cav2, Gsr, Nqo1, Nrp1, Anln, Fam96a, Lars2, G6pdx.
oxidation reduction (6), cell adhesion (2), glucose metabolic process (1), response to stress (1),
oxygen and reactive oxygen species metaboli... (1) GO:0006800, response to hypoxia (1),
response to oxidative stress (4), glutamate metabolic process (1), glutathione biosynthetic process
(1), response to drug (1), antioxidant activity (1), oxidoreductase activity (1).
Foxo6: cytoplasm, nucleus, sequence-specific DNA binding, transcription factor activity,
regulation of transcription, DNA-dependent, transcription.
Htatsf1: nucleus, nucleotide binding, RNA binding, regulation of transcription, transcription.
Ikbkg: nucleus, metal ion binding, B cell homeostasis, regulation of transcription, transcription.
Zfp1: nucleus, DNA binding, zinc ion binding, regulation of transcription, DNA-dependent,
transcription.
GO:0001558
P:regulation of cell growth|4|1|5.68449712643678|0.0416666666666667
GO:0007155
P:cell adhesion|23|2|2.01500249875063|0.0833333333333333
GO:0055114
P:oxidation reduction|42|6|15.2832019704434|0.25
GO:0006810
P:transport|10|1|1.35186781609195|0.0416666666666667
GO:0030154
P:cell differentiation|20|1|0.172485632183908|0.0416666666666667
GO:0005515
F:protein binding|105|3|0.0651477832512315|0.125
GO:0009055
F:electron carrier activity|6|1|3.23334291187739|0.0416666666666667
GO:0005488
F:binding|13|1|0.754062776304155|0.0416666666666667
GO:0005576
C:extracellular region|45|2|0.174840357598978|0.0833333333333333
GO:0005737
C:cytoplasm|100|4|0.14367816091954|0.166666666666667
GO:0016021
C:integral to membrane|175|6|0.00738916256157635|0.25
GO:0005789
C:endoplasmic reticulum membrane|26|1|0.0225486295313881|0.0416666666666667
GO:0005829
C:cytosol|24|1|0.0531633141762452|0.0416666666666667
GO:0006350
P:transcription|67|1|0.668801681248928|0.0416666666666667
GO:0045449
P:regulation of transcription|19|1|0.218877797943134|0.0416666666666667
GO:0006915
P:apoptosis|14|1|0.621186371100164|0.0416666666666667
GO:0007507
P:heart development|6|1|3.23334291187739|0.0416666666666667
GO:0007275
P:multicellular organismal
development|14|1|0.621186371100164|0.0416666666666667
GO:0006006
P:glucose metabolic process|3|1|8.16875478927203|0.0416666666666667
GO:0007411
P:axon guidance|5|1|4.20718390804598|0.0416666666666667
GO:0007413
P:axonal fasciculation|2|1|13.1703735632184|0.0416666666666667
GO:0060666
P:dichotomous subdivision of terminal units
i...|3|1|8.16875478927203|0.0416666666666667
GO:0048843
P:negative regulation of axon extension
invol...|2|1|13.1703735632184|0.0416666666666667
GO:0003677
F:DNA binding|30|1|4.78927203065136e-05|0.0416666666666667
GO:0008270
F:zinc ion binding|80|1|1.02588002873563|0.0416666666666667
GO:0005524
F:ATP binding|78|4|0.778650162098438|0.166666666666667
GO:0046982
F:protein heterodimerization activity|8|1|2.04086925287356|0.0416666666666667
GO:0042802
F:identical protein binding|10|1|1.35186781609195|0.0416666666666667
GO:0004867
F:serine-type endopeptidase inhibitor
activity|7|1|2.54720032840722|0.0416666666666667
GO:0005634
C:nucleus|118|4|0.00225209429183714|0.166666666666667
GO:0005739
C:mitochondrion|27|2|1.36910174542358|0.0833333333333333
GO:0009897
C:external side of plasma membrane|4|1|5.68449712643678|0.0416666666666667
GO:0005886
C:plasma membrane|62|2|0.00133852428624398|0.0833333333333333
GO:0000139
C:Golgi membrane|13|1|0.754062776304155|0.0416666666666667
GO:0005730
C:nucleolus|13|1|0.754062776304155|0.0416666666666667
GO:0051085
GO:0007166
P:chaperone mediated protein folding
requirin...|2|1|13.1703735632184|0.0416666666666667
P:cell surface receptor linked signaling
pathway|3|1|8.16875478927203|0.0416666666666667
GO:0006950
P:response to stress|2|1|13.1703735632184|0.0416666666666667
GO:0003779
F:actin binding|12|1|0.914602490421456|0.0416666666666667
GO:0005622
C:intracellular|14|1|0.621186371100164|0.0416666666666667
GO:0030424
C:axon|5|1|4.20718390804598|0.0416666666666667
GO:0031528
C:microvillus membrane|3|1|8.16875478927203|0.0416666666666667
GO:0009395
P:phospholipid catabolic process|1|1|28.2414367816092|0.0416666666666667
GO:0008637
P:apoptotic mitochondrial changes|1|1|28.2414367816092|0.0416666666666667
GO:0030262
P:apoptotic nuclear change|1|1|28.2414367816092|0.0416666666666667
GO:0032600
GO:0042632
GO:0007204
P:chemokine receptor transport out of
membran...|1|1|28.2414367816092|0.0416666666666667
P:cholesterol homeostasis|2|1|13.1703735632184|0.0416666666666667
P:elevation of cytosolic calcium ion
concentr...|1|1|28.2414367816092|0.0416666666666667
GO:0007157
P:heterophilic cell-cell adhesion|1|1|28.2414367816092|0.0416666666666667
GO:0034109
P:homotypic cell-cell adhesion|1|1|28.2414367816092|0.0416666666666667
GO:0008624
GO:0007159
GO:0002523
GO:0030889
GO:0034119
GO:0034107
P:induction of apoptosis by extracellular
sig...|1|1|28.2414367816092|0.0416666666666667
P:leukocyte cell-cell adhesion|2|1|13.1703735632184|0.0416666666666667
P:leukocyte migration during inflammatory
res...|1|1|28.2414367816092|0.0416666666666667
P:negative regulation of B cell
proliferation|1|1|28.2414367816092|0.0416666666666667
P:negative regulation of erythrocyte
aggregation|1|1|28.2414367816092|0.0416666666666667
P:negative regulation of erythrocyte
clearance|1|1|28.2414367816092|0.0416666666666667
GO:0007406
GO:0045665
GO:0046014
GO:0032913
P:negative regulation of neuroblast
prolifera...|1|1|28.2414367816092|0.0416666666666667
P:negative regulation of neuron
differentiation|2|1|13.1703735632184|0.0416666666666667
P:negative regulation of T cell homeostatic
p...|1|1|28.2414367816092|0.0416666666666667
P:negative regulation of transforming
growth ...|2|1|13.1703735632184|0.0416666666666667
GO:0007274
P:neuromuscular synaptic transmission|2|1|13.1703735632184|0.0416666666666667
GO:0031175
P:neuron projection development|2|1|13.1703735632184|0.0416666666666667
GO:0006800
GO:0042104
GO:0046641
GO:0002904
GO:0050850
GO:0033634
GO:0002863
GO:0033625
GO:0043406
GO:0050731
GO:0042103
GO:0002842
P:oxygen and reactive oxygen species
metaboli...|1|1|28.2414367816092|0.0416666666666667
P:positive regulation of activated T cell
pro...|1|1|28.2414367816092|0.0416666666666667
P:positive regulation of alpha-beta T cell
pr...|1|1|28.2414367816092|0.0416666666666667
P:positive regulation of B cell apoptosis|1|1|28.2414367816092|0.0416666666666667
P:positive regulation of calcium-mediated
sig...|1|1|28.2414367816092|0.0416666666666667
P:positive regulation of cell-cell adhesion
m...|2|1|13.1703735632184|0.0416666666666667
P:positive regulation of inflammatory
respons...|1|1|28.2414367816092|0.0416666666666667
P:positive regulation of integrin activation|1|1|28.2414367816092|0.0416666666666667
P:positive regulation of MAP kinase
activity|1|1|28.2414367816092|0.0416666666666667
P:positive regulation of peptidyl-tyrosine
ph...|2|1|13.1703735632184|0.0416666666666667
P:positive regulation of T cell homeostatic
p...|1|1|28.2414367816092|0.0416666666666667
P:positive regulation of T cell mediated
immu...|1|1|28.2414367816092|0.0416666666666667
GO:0002329
P:pre-B cell differentiation|1|1|28.2414367816092|0.0416666666666667
GO:0045577
P:regulation of B cell differentiation|1|1|28.2414367816092|0.0416666666666667
GO:0001959
P:regulation of cytokine-mediated signaling
p...|1|1|28.2414367816092|0.0416666666666667
GO:0043408
P:regulation of MAPKKK cascade|1|1|28.2414367816092|0.0416666666666667
GO:0045730
P:respiratory burst|1|1|28.2414367816092|0.0416666666666667
GO:0043627
P:response to estrogen stimulus|5|1|4.20718390804598|0.0416666666666667
GO:0001666
P:response to hypoxia|6|1|3.23334291187739|0.0416666666666667
GO:0002237
P:response to molecule of bacterial origin|2|1|13.1703735632184|0.0416666666666667
GO:0048488
P:synaptic vesicle endocytosis|1|1|28.2414367816092|0.0416666666666667
GO:0031295
P:T cell costimulation|1|1|28.2414367816092|0.0416666666666667
GO:0001649
P:osteoblast differentiation|2|1|13.1703735632184|0.0416666666666667
GO:0043065
P:positive regulation of apoptosis|5|1|4.20718390804598|0.0416666666666667
GO:0045663
GO:0009186
GO:0009263
P:positive regulation of myoblast
differentia...|2|1|13.1703735632184|0.0416666666666667
P:deoxyribonucleoside diphosphate metabolic
p...|1|1|28.2414367816092|0.0416666666666667
P:deoxyribonucleotide biosynthetic
process|1|1|28.2414367816092|0.0416666666666667
GO:0006260
P:DNA replication|9|1|1.65441251596424|0.0416666666666667
GO:0051290
P:protein heterotetramerization|1|1|28.2414367816092|0.0416666666666667
GO:0016998
P:cell wall macromolecule catabolic
process|2|1|13.1703735632184|0.0416666666666667
GO:0006979
P:response to oxidative stress|8|4|52.6814942528736|0.166666666666667
GO:0006536
P:glutamate metabolic process|2|1|13.1703735632184|0.0416666666666667
GO:0006750
P:glutathione biosynthetic process|2|1|13.1703735632184|0.0416666666666667
GO:0043524
P:negative regulation of neuron apoptosis|2|1|13.1703735632184|0.0416666666666667
GO:0035229
P:positive regulation of glutamate-cysteine
l...|1|1|28.2414367816092|0.0416666666666667
GO:0050880
P:regulation of blood vessel size|3|1|8.16875478927203|0.0416666666666667
GO:0042493
P:response to drug|2|1|13.1703735632184|0.0416666666666667
GO:0051409
P:response to nitrosative stress|1|1|28.2414367816092|0.0416666666666667
GO:0070836
P:caveola assembly|1|1|28.2414367816092|0.0416666666666667
GO:0007029
P:endoplasmic reticulum organization|1|1|28.2414367816092|0.0416666666666667
GO:0007005
P:mitochondrion organization|2|1|13.1703735632184|0.0416666666666667
GO:0001937
GO:0060161
P:negative regulation of endothelial cell
pro...|1|1|28.2414367816092|0.0416666666666667
P:positive regulation of dopamine receptor
si...|1|1|28.2414367816092|0.0416666666666667
GO:0048741
P:skeletal muscle fiber development|1|1|28.2414367816092|0.0416666666666667
GO:0048278
P:vesicle docking|1|1|28.2414367816092|0.0416666666666667
GO:0006906
P:vesicle fusion|1|1|28.2414367816092|0.0416666666666667
GO:0045454
P:cell redox homeostasis|7|1|2.54720032840722|0.0416666666666667
GO:0006749
P:glutathione metabolic process|2|1|13.1703735632184|0.0416666666666667
GO:0043525
P:positive regulation of neuron apoptosis|1|1|28.2414367816092|0.0416666666666667
GO:0016477
P:cell migration|2|1|13.1703735632184|0.0416666666666667
GO:0016358
P:dendrite development|2|1|13.1703735632184|0.0416666666666667
GO:0001569
P:patterning of blood vessels|1|1|28.2414367816092|0.0416666666666667
GO:0005021
F:vascular endothelial growth factor
receptor...|3|1|8.16875478927203|0.0416666666666667
GO:0007067
P:mitosis|4|1|5.68449712643678|0.0416666666666667
GO:0006429
P:leucyl-tRNA aminoacylation|1|1|28.2414367816092|0.0416666666666667
GO:0004622
F:lysophospholipase activity|1|1|28.2414367816092|0.0416666666666667
GO:0030246
F:carbohydrate binding|1|1|28.2414367816092|0.0416666666666667
GO:0043499
F:eukaryotic cell surface binding|1|1|28.2414367816092|0.0416666666666667
GO:0019901
F:protein kinase binding|5|1|4.20718390804598|0.0416666666666667
GO:0030296
F:protein tyrosine kinase activator activity|1|1|28.2414367816092|0.0416666666666667
GO:0008083
F:growth factor activity|9|1|1.65441251596424|0.0416666666666667
GO:0005173
F:stem cell factor receptor binding|1|1|28.2414367816092|0.0416666666666667
GO:0008160
F:protein tyrosine phosphatase activator
acti...|1|1|28.2414367816092|0.0416666666666667
GO:0016959
F:class I ribonucleotide reductase activity|1|1|28.2414367816092|0.0416666666666667
GO:0046914
F:transition metal ion binding|1|1|28.2414367816092|0.0416666666666667
GO:0042624
F:ATPase activity, uncoupled|1|1|28.2414367816092|0.0416666666666667
GO:0016209
F:antioxidant activity|1|1|28.2414367816092|0.0416666666666667
GO:0032542
F:sulfiredoxin activity|1|1|28.2414367816092|0.0416666666666667
GO:0004357
F:glutamate-cysteine ligase activity|2|1|13.1703735632184|0.0416666666666667
GO:0035226
F:glutamate-cysteine ligase catalytic
subunit...|1|1|28.2414367816092|0.0416666666666667
GO:0016491
F:oxidoreductase activity|4|1|5.68449712643678|0.0416666666666667
GO:0008195
F:phosphatidate phosphatase activity|1|1|28.2414367816092|0.0416666666666667
GO:0031748
F:D1 dopamine receptor binding|1|1|28.2414367816092|0.0416666666666667
GO:0004362
F:glutathione-disulfide reductase activity|1|1|28.2414367816092|0.0416666666666667
GO:0050662
F:coenzyme binding|2|1|13.1703735632184|0.0416666666666667
GO:0003955
F:NAD(P)H dehydrogenase (quinone)
activity|1|1|28.2414367816092|0.0416666666666667
GO:0017154
F:semaphorin receptor activity|1|1|28.2414367816092|0.0416666666666667
GO:0004823
F:leucine-tRNA ligase activity|1|1|28.2414367816092|0.0416666666666667
GO:0004345
GO:0031362
F:glucose-6-phosphate dehydrogenase
activity|1|1|28.2414367816092|0.0416666666666667
C:anchored to external side of plasma
membrane|1|1|28.2414367816092|0.0416666666666667
GO:0060170
C:cilium membrane|1|1|28.2414367816092|0.0416666666666667
GO:0005624
C:membrane fraction|10|1|1.35186781609195|0.0416666666666667
GO:0045121
C:membrane raft|4|1|5.68449712643678|0.0416666666666667
GO:0010008
C:endosome membrane|4|1|5.68449712643678|0.0416666666666667
GO:0005765
C:lysosomal membrane|3|1|8.16875478927203|0.0416666666666667
GO:0017109
C:glutamate-cysteine ligase complex|2|1|13.1703735632184|0.0416666666666667
GO:0005625
C:soluble fraction|1|1|28.2414367816092|0.0416666666666667
GO:0005901
C:caveola|1|1|28.2414367816092|0.0416666666666667
GO:0031234
GO:0048471
6
0.3574
25
C:extrinsic to internal side of plasma
membrane|2|1|13.1703735632184|0.0416666666666667
C:perinuclear region of cytoplasm|4|1|5.68449712643678|0.0416666666666667
Ctgf, Txnrd1, Irgm1, Slc9a3r1, Fasn, Dync1h1, Ctla2a, Pck2, Cdc42ep1, Naga, Tfrc, Rps2, Ltbp3,
Aldh18a1, Ogfr, Txnip, Txnip, Dhcr24, Mmp23, Insig1, Ccni, Atn1, Mmp2, Fam38a, Ldlr.
oxidation reduction (4), fatty acid biosynthetic process (1), cholesterol biosynthetic process (2),
response to oxidative stress (1), gluconeogenesis (1), glutamate 5-kinase activity (1),
glutamate-5-semialdehyde dehydrogenase acti... (1) GO:0004350.
Bnc1: cytoplasm, nucleus, DNA binding, zinc ion binding, regulation of transcription,
transcription.
Foxo6: cytoplasm, nucleus, sequence-specific DNA binding, transcription factor activity,
regulation of transcription, DNA-dependent, transcription.
Htatsf1: nucleus, nucleotide binding, RNA binding, regulation of transcription, transcription.
Ikbkg: nucleus, metal ion binding, B cell homeostasis, regulation of transcription, transcription.
Irf7: cytoplasm, nucleus, protein binding, transcription factor activity, immunoglobulin mediated
immune response, regulation of transcription, DNA-dependent, response to virus, transcription,
type I interferon biosynthetic process.
GO:0001558
P:regulation of cell growth|4|1|5.38793103448276|0.04
GO:0055114
P:oxidation reduction|42|4|4.49589490968801|0.16
GO:0006633
P:fatty acid biosynthetic process|4|1|5.38793103448276|0.04
GO:0006810
P:transport|10|1|1.2448275862069|0.04
GO:0001525
P:angiogenesis|8|2|10.7758620689655|0.08
GO:0006695
P:cholesterol biosynthetic process|6|2|15.5402298850575|0.08
GO:0030154
P:cell differentiation|20|1|0.139655172413793|0.04
GO:0005520
F:insulin-like growth factor binding|2|1|12.5689655172414|0.04
GO:0005515
F:protein binding|105|4|0.0397372742200329|0.16
GO:0050660
F:FAD binding|6|2|15.5402298850575|0.08
GO:0005509
F:calcium ion binding|39|2|0.319186560565871|0.08
GO:0005178
F:integrin binding|5|1|3.97241379310345|0.04
GO:0042605
F:peptide antigen binding|3|1|7.77011494252874|0.04
GO:0016020
C:membrane|21|1|0.105090311986864|0.04
GO:0005578
C:proteinaceous extracellular matrix|15|2|4.25057471264368|0.08
GO:0005576
C:extracellular region|45|2|0.129501915708812|0.08
GO:0005737
C:cytoplasm|100|2|0.608275862068965|0.08
GO:0016021
C:integral to membrane|175|6|0.000197044334975368|0.24
GO:0005789
C:endoplasmic reticulum membrane|26|3|4.93501326259947|0.12
GO:0016324
C:apical plasma membrane|5|1|3.97241379310345|0.04
GO:0005829
C:cytosol|24|2|1.66091954022989|0.08
GO:0006350
P:transcription|67|2|0.0416881111682964|0.08
GO:0016055
P:Wnt receptor signaling pathway|9|1|1.53256704980843|0.04
GO:0006561
P:proline biosynthetic process|3|1|7.77011494252874|0.04
GO:0007160
P:cell-matrix adhesion|9|1|1.53256704980843|0.04
GO:0007229
P:integrin-mediated signaling pathway|5|1|3.97241379310345|0.04
GO:0008203
P:cholesterol metabolic process|3|1|7.77011494252874|0.04
GO:0006897
P:endocytosis|8|2|10.7758620689655|0.08
GO:0007049
P:cell cycle|9|2|9.1992337164751|0.08
GO:0006412
P:translation|6|1|3.04022988505747|0.04
GO:0043588
P:skin development|2|1|12.5689655172414|0.04
GO:0006879
P:cellular iron ion homeostasis|3|1|7.77011494252874|0.04
GO:0005525
F:GTP binding|22|2|2.03134796238245|0.08
GO:0008270
F:zinc ion binding|80|3|0.0211206896551724|0.12
GO:0046872
F:metal ion binding|27|1|0.00510855683269477|0.04
GO:0005524
F:ATP binding|78|2|0.17683465959328|0.08
GO:0004872
F:receptor activity|30|1|0.00114942528735633|0.04
GO:0030229
F:very-low-density lipoprotein receptor activity|3|1|7.77011494252874|0.04
GO:0003723
F:RNA binding|20|1|0.139655172413793|0.04
GO:0003735
F:structural constituent of ribosome|4|1|5.38793103448276|0.04
GO:0008234
F:cysteine-type peptidase activity|2|1|12.5689655172414|0.04
GO:0005634
C:nucleus|118|4|0.00116890707188777|0.16
GO:0005739
C:mitochondrion|27|3|4.59770114942529|0.12
GO:0005886
C:plasma membrane|62|3|0.347608453837598|0.12
GO:0000139
C:Golgi membrane|13|2|5.37135278514589|0.08
GO:0005743
C:mitochondrial inner membrane|6|1|3.04022988505747|0.04
GO:0005856
C:cytoskeleton|16|2|3.80172413793104|0.08
GO:0005905
C:coated pit|5|1|3.97241379310345|0.04
GO:0001502
P:cartilage condensation|3|1|7.77011494252874|0.04
GO:0042472
P:inner ear morphogenesis|3|1|7.77011494252874|0.04
GO:0045087
P:innate immune response|13|1|0.679045092838196|0.04
GO:0005764
C:lysosome|5|1|3.97241379310345|0.04
GO:0008283
P:cell proliferation|7|1|2.38423645320197|0.04
GO:0008360
P:regulation of cell shape|8|1|1.90086206896552|0.04
GO:0042474
P:middle ear morphogenesis|2|1|12.5689655172414|0.04
GO:0060021
P:palate development|2|1|12.5689655172414|0.04
GO:0050661
F:NADP or NADPH binding|4|1|5.38793103448276|0.04
GO:0042632
P:cholesterol homeostasis|2|1|12.5689655172414|0.04
GO:0001666
P:response to hypoxia|6|1|3.04022988505747|0.04
GO:0006260
P:DNA replication|9|1|1.53256704980843|0.04
GO:0006979
P:response to oxidative stress|8|1|1.90086206896552|0.04
GO:0045454
P:cell redox homeostasis|7|1|2.38423645320197|0.04
GO:0016477
P:cell migration|2|1|12.5689655172414|0.04
GO:0005624
C:membrane fraction|10|1|1.2448275862069|0.04
GO:0048471
C:perinuclear region of cytoplasm|4|1|5.38793103448276|0.04
GO:0008543
P:fibroblast growth factor receptor signaling...|1|1|27.0344827586207|0.04
GO:0030324
P:lung development|3|1|7.77011494252874|0.04
GO:0001503
P:ossification|3|1|7.77011494252874|0.04
GO:0001707
P:mesoderm formation|4|1|5.38793103448276|0.04
GO:0006914
P:autophagy|4|1|5.38793103448276|0.04
GO:0030643
P:cellular phosphate ion homeostasis|1|1|27.0344827586207|0.04
GO:0006094
P:gluconeogenesis|1|1|27.0344827586207|0.04
GO:0007266
P:Rho protein signal transduction|1|1|27.0344827586207|0.04
GO:0016052
P:carbohydrate catabolic process|1|1|27.0344827586207|0.04
GO:0019377
P:glycolipid catabolic process|1|1|27.0344827586207|0.04
GO:0006508
P:proteolysis|19|3|8.39201451905626|0.12
GO:0040008
P:regulation of growth|4|1|5.38793103448276|0.04
GO:0030216
P:keratinocyte differentiation|3|2|34.7701149425287|0.08
GO:0006916
P:anti-apoptosis|6|1|3.04022988505747|0.04
GO:0043154
P:negative regulation of caspase activity|3|1|7.77011494252874|0.04
GO:0008285
P:negative regulation of cell proliferation|6|1|3.04022988505747|0.04
GO:0007265
P:Ras protein signal transduction|1|1|27.0344827586207|0.04
GO:0000003
P:reproduction|1|1|27.0344827586207|0.04
GO:0060363
P:cranial suture morphogenesis|1|1|27.0344827586207|0.04
GO:0045599
P:negative regulation of fat cell differentia...|3|1|7.77011494252874|0.04
GO:0045717
P:negative regulation of fatty acid biosynthe...|1|1|27.0344827586207|0.04
GO:0010894
P:negative regulation of steroid biosynthetic...|1|1|27.0344827586207|0.04
GO:0006991
P:response to sterol depletion|1|1|27.0344827586207|0.04
GO:0006641
P:triglyceride metabolic process|2|1|12.5689655172414|0.04
GO:0051726
P:regulation of cell cycle|1|1|27.0344827586207|0.04
GO:0045664
P:regulation of neuron differentiation|1|1|27.0344827586207|0.04
GO:0001955
P:blood vessel maturation|1|1|27.0344827586207|0.04
GO:0060346
P:bone trabecula formation|1|1|27.0344827586207|0.04
GO:0030574
P:collagen catabolic process|4|1|5.38793103448276|0.04
GO:0060325
P:face morphogenesis|1|1|27.0344827586207|0.04
GO:0001957
P:intramembranous ossification|1|1|27.0344827586207|0.04
GO:0042159
P:lipoprotein catabolic process|1|1|27.0344827586207|0.04
GO:0008201
F:heparin binding|5|1|3.97241379310345|0.04
GO:0004791
F:thioredoxin-disulfide reductase activity|3|1|7.77011494252874|0.04
GO:0016817
F:hydrolase activity, acting on acid anhydrides|6|1|3.04022988505747|0.04
GO:0004317
F:3-hydroxypalmitoyl-[acyl-carrier-protein] d...|1|1|27.0344827586207|0.04
GO:0004316
F:3-oxoacyl-[acyl-carrier-protein] reductase ...|1|1|27.0344827586207|0.04
GO:0004315
F:3-oxoacyl-[acyl-carrier-protein] synthase a...|1|1|27.0344827586207|0.04
GO:0004313
F:[acyl-carrier-protein] S-acetyltransferase ...|1|1|27.0344827586207|0.04
GO:0004314
F:[acyl-carrier-protein] S-malonyltransferase...|1|1|27.0344827586207|0.04
GO:0000036
F:acyl carrier activity|2|1|12.5689655172414|0.04
GO:0048037
F:cofactor binding|2|1|12.5689655172414|0.04
GO:0004319
F:enoyl-[acyl-carrier-protein] reductase (NAD...|1|1|27.0344827586207|0.04
GO:0004320
F:oleoyl-[acyl-carrier-protein] hydrolase act...|1|1|27.0344827586207|0.04
GO:0031177
F:phosphopantetheine binding|2|1|12.5689655172414|0.04
GO:0016887
F:ATPase activity|5|1|3.97241379310345|0.04
GO:0003777
F:microtubule motor activity|2|1|12.5689655172414|0.04
GO:0004613
F:phosphoenolpyruvate carboxykinase (GTP) act...|1|1|27.0344827586207|0.04
GO:0008456
F:alpha-N-acetylgalactosaminidase activity|1|1|27.0344827586207|0.04
GO:0043169
F:cation binding|2|1|12.5689655172414|0.04
GO:0005381
F:iron ion transmembrane transporter activity|1|1|27.0344827586207|0.04
GO:0008233
F:peptidase activity|1|1|27.0344827586207|0.04
GO:0004998
F:transferrin receptor activity|1|1|27.0344827586207|0.04
GO:0019838
F:growth factor binding|2|1|12.5689655172414|0.04
GO:0004349
F:glutamate 5-kinase activity|2|1|12.5689655172414|0.04
GO:0004350
F:glutamate-5-semialdehyde dehydrogenase acti...|2|1|12.5689655172414|0.04
GO:0050614
F:delta24-sterol reductase activity|1|1|27.0344827586207|0.04
GO:0019899
F:enzyme binding|1|1|27.0344827586207|0.04
GO:0004222
F:metalloendopeptidase activity|8|2|10.7758620689655|0.08
GO:0008432
F:JUN kinase binding|1|1|27.0344827586207|0.04
GO:0005041
F:low-density lipoprotein receptor activity|1|1|27.0344827586207|0.04
GO:0000421
C:autophagic vacuole membrane|3|1|7.77011494252874|0.04
GO:0030670
C:phagocytic vesicle membrane|4|1|5.38793103448276|0.04
GO:0012505
C:endomembrane system|3|2|34.7701149425287|0.08
GO:0042587
C:glycogen granule|1|1|27.0344827586207|0.04
GO:0042470
C:melanosome|5|2|19.3724137931034|0.08
GO:0030286
C:dynein complex|1|1|27.0344827586207|0.04
GO:0005874
C:microtubule|5|1|3.97241379310345|0.04
GO:0005768
C:endosome|3|2|34.7701149425287|0.08
GO:0070062
C:extracellular vesicular exosome|1|1|27.0344827586207|0.04
GO:0015935
C:small ribosomal subunit|2|1|12.5689655172414|0.04
GO:0031012
C:extracellular matrix|3|1|7.77011494252874|0.04
GO:0030017
C:sarcomere|1|1|27.0344827586207|0.04
GO:0033116
C:ER-Golgi intermediate compartment membrane|2|1|12.5689655172414|0.04
GO:0034362
C:low-density lipoprotein particle|1|1|27.0344827586207|0.04
12
0.6212
31
Lss, Aldh1l2, Chd3, Fzd2, Zfp36l1, 4930486L24Rik, Clu, Dpysl2, Gsdmd, Adamts5, H2-D1,
Eif2ak2, Gata6, Isoc1, Ifit2, Ciz1, Creb3l1, Trib3, Pltp, Npepl1, Sprr1a, Sema3c, Ttyh3,
2610001J05Rik, C1s, Slc1a5, Prss23, Gpr124, Tecr, B3gnt9-ps, Cdon.
oxidation reduction (2), response to virus (2), metabolic process (1), smoothened signaling
pathway (1), mRNA binding (1), aminopeptidase activity (1), oxidoreductase activity, acting on
the CH-C... (1) GO:0016627.
Bnc1: cytoplasm, nucleus, DNA binding, zinc ion binding, regulation of transcription,
transcription.
Htatsf1: nucleus, nucleotide binding, RNA binding, regulation of transcription, transcription.
Ikbkg: nucleus, metal ion binding, B cell homeostasis, regulation of transcription, transcription.
Irf7: cytoplasm, nucleus, protein binding, transcription factor activity, immunoglobulin mediated
immune response, regulation of transcription, DNA-dependent, response to virus, transcription,
type I interferon biosynthetic process.
GO:0055114
P:oxidation reduction|42|2|0.0232046188887124|0.0645161290322581
GO:0009615
P:response to virus|9|2|6.77909281918181|0.0645161290322581
GO:0030154
P:cell differentiation|20|1|0.0245272525027809|0.032258064516129
GO:0007399
P:nervous system development|10|1|0.766295884315907|0.032258064516129
GO:0005515
F:protein binding|105|6|0.508088352137295|0.193548387096774
GO:0005509
F:calcium ion binding|39|1|0.267255354952797|0.032258064516129
GO:0005488
F:binding|13|1|0.354869513134252|0.032258064516129
GO:0005615
C:extracellular space|27|2|0.619237836278993|0.0645161290322581
GO:0016020
C:membrane|21|1|0.0116023094443562|0.032258064516129
GO:0005578
C:proteinaceous extracellular matrix|15|1|0.200519095291064|0.032258064516129
GO:0005576
C:extracellular region|45|1|0.443851192683228|0.032258064516129
GO:0005777
C:peroxisome|4|1|4.01780867630701|0.032258064516129
GO:0005737
C:cytoplasm|100|2|1.21134593993326|0.0645161290322581
GO:0016021
C:integral to membrane|175|8|0.0357540123947244|0.258064516129032
GO:0005789
C:endoplasmic reticulum membrane|26|3|3.20725763669034|0.0967741935483871
GO:0005829
C:cytosol|24|1|0.000669262143121988|0.032258064516129
GO:0008152
P:metabolic process|9|1|0.983393894450624|0.032258064516129
GO:0006355
P:regulation of transcription,
DNA-dependent|30|1|0.0623285131627734|0.032258064516129
GO:0006350
P:transcription|67|4|0.449805920342669|0.129032258064516
GO:0045449
P:regulation of transcription|19|1|0.0433136233241613|0.032258064516129
GO:0006915
P:apoptosis|14|2|3.28064833942476|0.0645161290322581
GO:0009791
P:post-embryonic development|2|1|9.77906562847608|0.032258064516129
GO:0031424
P:keratinization|2|1|9.77906562847608|0.032258064516129
GO:0006869
P:lipid transport|4|1|4.01780867630701|0.032258064516129
GO:0007165
P:signal transduction|35|1|0.16475448911489|0.032258064516129
GO:0050830
GO:0032760
GO:0006412
GO:0060666
P:defense response to Gram-positive
bacterium|3|1|5.92397478680015|0.032258064516129
P:positive regulation of tumor necrosis
facto...|6|2|11.8479495736003|0.0645161290322581
P:translation|6|1|2.15440118650352|0.032258064516129
P:dichotomous subdivision of terminal units
i...|3|1|5.92397478680015|0.032258064516129
GO:0003700
F:transcription factor activity|32|1|0.0991226362625139|0.032258064516129
GO:0003677
F:DNA binding|30|2|0.401038190582128|0.0645161290322581
GO:0008270
F:zinc ion binding|80|5|0.729157397107898|0.161290322580645
GO:0046872
F:metal ion binding|27|1|0.0206715280352655|0.032258064516129
GO:0005524
F:ATP binding|78|3|0.0336835800462052|0.0967741935483871
GO:0004872
F:receptor activity|30|1|0.0623285131627734|0.032258064516129
GO:0043565
F:sequence-specific DNA binding|15|1|0.200519095291064|0.032258064516129
GO:0016563
F:transcription activator activity|5|1|2.89121245828699|0.032258064516129
GO:0003725
F:double-stranded RNA binding|5|1|2.89121245828699|0.032258064516129
GO:0003682
F:chromatin binding|6|2|11.8479495736003|0.0645161290322581
GO:0009986
C:cell surface|4|1|4.01780867630701|0.032258064516129
GO:0005634
C:nucleus|118|4|0.216649007371656|0.129032258064516
GO:0005739
C:mitochondrion|27|2|0.619237836278993|0.0645161290322581
GO:0005886
C:plasma membrane|62|2|0.159879435932398|0.0645161290322581
GO:0000139
C:Golgi membrane|13|1|0.354869513134252|0.032258064516129
GO:0006955
P:immune response|18|1|0.0689383265356569|0.032258064516129
GO:0045087
P:innate immune response|13|3|10.7469290664841|0.0967741935483871
GO:0003676
F:nucleic acid binding|8|1|1.26545606229144|0.032258064516129
GO:0004930
F:G-protein coupled receptor activity|9|2|6.77909281918181|0.0645161290322581
GO:0005102
F:receptor binding|8|1|1.26545606229144|0.032258064516129
GO:0005764
C:lysosome|5|1|2.89121245828699|0.032258064516129
GO:0005622
C:intracellular|14|2|3.28064833942476|0.0645161290322581
GO:0042612
C:MHC class I protein complex|4|1|4.01780867630701|0.032258064516129
GO:0016337
P:cell-cell adhesion|2|1|9.77906562847608|0.032258064516129
GO:0001701
P:in utero embryonic development|5|1|2.89121245828699|0.032258064516129
GO:0043627
P:response to estrogen stimulus|5|1|2.89121245828699|0.032258064516129
GO:0045663
P:positive regulation of myoblast
differentia...|2|1|9.77906562847608|0.032258064516129
GO:0019901
F:protein kinase binding|5|1|2.89121245828699|0.032258064516129
GO:0006508
P:proteolysis|19|5|21.5849095486213|0.161290322580645
GO:0000036
F:acyl carrier activity|2|1|9.77906562847608|0.032258064516129
GO:0048037
F:cofactor binding|2|1|9.77906562847608|0.032258064516129
GO:0031177
F:phosphopantetheine binding|2|1|9.77906562847608|0.032258064516129
GO:0004222
F:metalloendopeptidase activity|8|1|1.26545606229144|0.032258064516129
GO:0042470
C:melanosome|5|1|2.89121245828699|0.032258064516129
GO:0003714
F:transcription corepressor activity|6|1|2.15440118650352|0.032258064516129
GO:0006357
P:regulation of transcription from RNA
polyme...|7|1|1.64032416971238|0.032258064516129
GO:0007267
P:cell-cell signaling|7|1|1.64032416971238|0.032258064516129
GO:0006486
P:protein amino acid glycosylation|4|1|4.01780867630701|0.032258064516129
GO:0006811
P:ion transport|7|1|1.64032416971238|0.032258064516129
GO:0002474
GO:0001755
GO:0090023
P:antigen processing and presentation of
pept...|3|1|5.92397478680015|0.032258064516129
P:neural crest cell migration|2|1|9.77906562847608|0.032258064516129
P:positive regulation of neutrophil
chemotaxis|3|1|5.92397478680015|0.032258064516129
GO:0004252
F:serine-type endopeptidase activity|6|2|11.8479495736003|0.0645161290322581
GO:0005254
F:chloride channel activity|4|1|4.01780867630701|0.032258064516129
GO:0046983
F:protein dimerization activity|7|1|1.64032416971238|0.032258064516129
GO:0007218
P:neuropeptide signaling pathway|5|1|2.89121245828699|0.032258064516129
GO:0003824
F:catalytic activity|2|1|9.77906562847608|0.032258064516129
GO:0004197
F:cysteine-type endopeptidase activity|2|1|9.77906562847608|0.032258064516129
GO:0006730
P:one-carbon metabolic process|4|1|4.01780867630701|0.032258064516129
GO:0016568
P:chromatin modification|2|1|9.77906562847608|0.032258064516129
GO:0010552
P:positive regulation of gene-specific
transc...|4|1|4.01780867630701|0.032258064516129
GO:0006958
P:complement activation, classical pathway|4|2|19.5581312569522|0.0645161290322581
GO:0006468
P:protein amino acid phosphorylation|11|1|0.596444534331075|0.032258064516129
GO:0006629
P:lipid metabolic process|2|1|9.77906562847608|0.032258064516129
GO:0046777
P:protein amino acid autophosphorylation|5|1|2.89121245828699|0.032258064516129
GO:0004674
F:protein serine/threonine kinase activity|7|1|1.64032416971238|0.032258064516129
GO:0001889
P:liver development|3|1|5.92397478680015|0.032258064516129
GO:0003705
GO:0004672
GO:0016810
GO:0009258
F:RNA polymerase II transcription factor
acti...|3|1|5.92397478680015|0.032258064516129
F:protein kinase activity|3|1|5.92397478680015|0.032258064516129
F:hydrolase activity, acting on
carbon-nitrog...|2|1|9.77906562847608|0.032258064516129
P:10-formyltetrahydrofolate catabolic
process|1|1|21.4298553948832|0.032258064516129
GO:0009058
P:biosynthetic process|2|1|9.77906562847608|0.032258064516129
GO:0006333
P:chromatin assembly or disassembly|2|1|9.77906562847608|0.032258064516129
GO:0030855
P:epithelial cell differentiation|1|1|21.4298553948832|0.032258064516129
GO:0032463
GO:0001836
P:negative regulation of protein
homooligomer...|1|1|21.4298553948832|0.032258064516129
P:release of cytochrome c from
mitochondria|3|1|5.92397478680015|0.032258064516129
GO:0051788
P:response to misfolded protein|1|1|21.4298553948832|0.032258064516129
GO:0043691
P:reverse cholesterol transport|1|1|21.4298553948832|0.032258064516129
GO:0030968
GO:0033689
P:endoplasmic reticulum unfolded protein
resp...|1|1|21.4298553948832|0.032258064516129
P:negative regulation of osteoblast
prolifera...|1|1|21.4298553948832|0.032258064516129
GO:0006926
P:virus-infected cell apoptosis|1|1|21.4298553948832|0.032258064516129
GO:0055007
P:cardiac muscle cell differentiation|1|1|21.4298553948832|0.032258064516129
GO:0071371
P:cellular response to gonadotropin stimulus|1|1|21.4298553948832|0.032258064516129
GO:0060486
P:Clara cell differentiation|1|1|21.4298553948832|0.032258064516129
GO:0007492
P:endoderm development|1|1|21.4298553948832|0.032258064516129
GO:0060430
P:lung saccule development|1|1|21.4298553948832|0.032258064516129
GO:0048645
P:organ formation|1|1|21.4298553948832|0.032258064516129
GO:0003310
P:pancreatic A cell differentiation|1|1|21.4298553948832|0.032258064516129
GO:0003309
P:pancreatic B cell differentiation|1|1|21.4298553948832|0.032258064516129
GO:0006644
P:phospholipid metabolic process|1|1|21.4298553948832|0.032258064516129
GO:0051891
P:positive regulation of cardioblast
differen...|1|1|21.4298553948832|0.032258064516129
GO:0060510
P:Type II pneumocyte differentiation|1|1|21.4298553948832|0.032258064516129
GO:0006986
P:response to unfolded protein|3|1|5.92397478680015|0.032258064516129
GO:0006469
P:negative regulation of protein kinase
activity|1|1|21.4298553948832|0.032258064516129
GO:0043405
P:regulation of MAP kinase activity|1|1|21.4298553948832|0.032258064516129
GO:0006953
P:acute-phase response|2|1|9.77906562847608|0.032258064516129
GO:0050829
P:defense response to Gram-negative
bacterium|2|1|9.77906562847608|0.032258064516129
GO:0002232
GO:0002281
GO:0044130
GO:0008228
GO:0032722
P:leukocyte chemotaxis during inflammatory
re...|2|1|9.77906562847608|0.032258064516129
P:macrophage activation during immune
response|2|1|9.77906562847608|0.032258064516129
P:negative regulation of growth of symbiont
i...|2|1|9.77906562847608|0.032258064516129
P:opsonization|2|1|9.77906562847608|0.032258064516129
P:positive regulation of chemokine
production|2|1|9.77906562847608|0.032258064516129
GO:0060265
P:positive regulation of respiratory burst in...|2|1|9.77906562847608|0.032258064516129
GO:0001974
P:blood vessel remodeling|1|1|21.4298553948832|0.032258064516129
GO:0003215
P:cardiac right ventricle morphogenesis|1|1|21.4298553948832|0.032258064516129
GO:0060174
P:limb bud formation|1|1|21.4298553948832|0.032258064516129
GO:0021915
P:neural tube development|1|1|21.4298553948832|0.032258064516129
GO:0003151
P:outflow tract morphogenesis|1|1|21.4298553948832|0.032258064516129
GO:0003350
P:pulmonary myocardium development|1|1|21.4298553948832|0.032258064516129
GO:0001756
P:somitogenesis|1|1|21.4298553948832|0.032258064516129
GO:0006835
P:dicarboxylic acid transport|1|1|21.4298553948832|0.032258064516129
GO:0006694
P:steroid biosynthetic process|1|1|21.4298553948832|0.032258064516129
GO:0001708
P:cell fate specification|1|1|21.4298553948832|0.032258064516129
GO:0010172
P:embryonic body morphogenesis|1|1|21.4298553948832|0.032258064516129
GO:0007520
P:myoblast fusion|1|1|21.4298553948832|0.032258064516129
GO:0007224
P:smoothened signaling pathway|2|1|9.77906562847608|0.032258064516129
GO:0000250
F:lanosterol synthase activity|1|1|21.4298553948832|0.032258064516129
GO:0016155
GO:0016742
GO:0004003
GO:0004926
F:formyltetrahydrofolate dehydrogenase
activity|1|1|21.4298553948832|0.032258064516129
F:hydroxymethyl-, formyl- and related
transfe...|1|1|21.4298553948832|0.032258064516129
F:ATP-dependent DNA helicase activity|2|1|9.77906562847608|0.032258064516129
F:non-G-protein coupled 7TM receptor
activity|1|1|21.4298553948832|0.032258064516129
GO:0017091
F:AU-rich element binding|1|1|21.4298553948832|0.032258064516129
GO:0003729
F:mRNA binding|1|1|21.4298553948832|0.032258064516129
GO:0051787
F:misfolded protein binding|1|1|21.4298553948832|0.032258064516129
GO:0008134
F:transcription factor binding|2|1|9.77906562847608|0.032258064516129
GO:0004860
F:protein kinase inhibitor activity|1|1|21.4298553948832|0.032258064516129
GO:0051637
F:Gram-positive bacterial cell surface
binding|2|1|9.77906562847608|0.032258064516129
GO:0008289
F:lipid binding|3|1|5.92397478680015|0.032258064516129
GO:0001530
F:lipopolysaccharide binding|2|1|9.77906562847608|0.032258064516129
GO:0004177
F:aminopeptidase activity|1|1|21.4298553948832|0.032258064516129
GO:0030215
F:semaphorin receptor binding|1|1|21.4298553948832|0.032258064516129
GO:0015175
F:neutral amino acid transmembrane
transporte...|1|1|21.4298553948832|0.032258064516129
GO:0017153
GO:0016627
F:sodium:dicarboxylate symporter activity|1|1|21.4298553948832|0.032258064516129
F:oxidoreductase activity, acting on the
CH-C...|1|1|21.4298553948832|0.032258064516129
GO:0008378
F:galactosyltransferase activity|1|1|21.4298553948832|0.032258064516129
GO:0000785
C:chromatin|3|1|5.92397478680015|0.032258064516129
GO:0016581
C:NuRD complex|1|1|21.4298553948832|0.032258064516129
GO:0034366
C:spherical high-density lipoprotein particle|1|1|21.4298553948832|0.032258064516129
GO:0005667
C:transcription factor complex|3|1|5.92397478680015|0.032258064516129
GO:0034707
C:chloride channel complex|1|1|21.4298553948832|0.032258064516129
15
0.8115
33
Stat2, Ifi35, Ifi27l2a, Nid2, Fdft1, Rspo2, Glis2, Klhl24, Rtp4, Upk1b, Col8a1, Cxadr, Neat1,
Gm98, Ifit3, Ube2l6, Rin2, Ddx58, Ccnl2, Mvk, Oasl2, Upk3b, Samd9l, Gxylt2, C1s, Rassf8,
Tm7sf3, A430110N23Rik, Peg3, Gas2, Zfp358, Gpt2, Nsdhl.
oxidation reduction (2), response to virus (2), oxidoreductase activity (1), smoothened signaling
pathway (1), 2-oxoglutarate metabolic process (1), response to stimulus (1), cell adhesion (2),
angiogenesis (1).
Htatsf1: nucleus, nucleotide binding, RNA binding, regulation of transcription, transcription.
Ikbkg: nucleus, metal ion binding, B cell homeostasis, regulation of transcription, transcription.
Irf7: cytoplasm, nucleus, protein binding, transcription factor activity, immunoglobulin mediated
immune response, regulation of transcription, DNA-dependent, response to virus, transcription,
type I interferon biosynthetic process.
Peg3: nucleus, transcription factor activity, zinc ion binding, regulation of transcription,
DNA-dependent, transcription.
GO:0007155
P:cell adhesion|23|2|0.867713416019263|0.0606060606060606
GO:0055114
P:oxidation reduction|42|2|0.00407623028312683|0.0606060606060606
GO:0001525
P:angiogenesis|8|1|1.1103500522466|0.0303030303030303
GO:0009615
P:response to virus|9|2|6.17396493672356|0.0606060606060606
GO:0006695
P:cholesterol biosynthetic process|6|3|27.2276489028213|0.0909090909090909
GO:0030154
P:cell differentiation|20|1|0.00882967607105537|0.0303030303030303
GO:0007399
P:nervous system development|10|1|0.6521421107628|0.0303030303030303
GO:0005515
F:protein binding|105|6|0.311777877295119|0.181818181818182
GO:0005044
F:scavenger receptor activity|5|1|2.62152560083595|0.0303030303030303
GO:0005509
F:calcium ion binding|39|3|0.845102483723173|0.0909090909090909
GO:0005488
F:binding|13|2|3.35163089783779|0.0606060606060606
GO:0016020
C:membrane|21|3|4.37144648454993|0.0909090909090909
GO:0005576
C:extracellular region|45|3|0.44221525600836|0.0909090909090909
GO:0005777
C:peroxisome|4|1|3.67449320794148|0.0303030303030303
GO:0005737
C:cytoplasm|100|6|0.460815047021943|0.181818181818182
GO:0016021
C:integral to membrane|175|10|0.519629795491864|0.303030303030303
GO:0005789
C:endoplasmic reticulum membrane|26|1|0.028436620850414|0.0303030303030303
GO:0005604
C:basement membrane|6|2|10.9195680947405|0.0606060606060606
GO:0006355
P:regulation of transcription,
DNA-dependent|30|3|1.9564263322884|0.0909090909090909
GO:0006350
P:transcription|67|6|2.8542684695644|0.181818181818182
GO:0045449
P:regulation of transcription|19|1|0.0211274267172634|0.0303030303030303
GO:0016055
P:Wnt receptor signaling pathway|9|1|0.850732613491234|0.0303030303030303
GO:0006915
P:apoptosis|14|1|0.206505448574414|0.0303030303030303
GO:0007160
P:cell-matrix adhesion|9|1|0.850732613491234|0.0303030303030303
GO:0006897
P:endocytosis|8|1|1.1103500522466|0.0303030303030303
GO:0007165
P:signal transduction|35|3|1.24245409762651|0.0909090909090909
GO:0004871
F:signal transducer activity|6|1|1.93471960989202|0.0303030303030303
GO:0003700
F:transcription factor activity|32|3|1.6355289968652|0.0909090909090909
GO:0003677
F:DNA binding|30|2|0.29481017067224|0.0606060606060606
GO:0008270
F:zinc ion binding|80|4|0.0353187042842215|0.121212121212121
GO:0005524
F:ATP binding|78|4|0.0569493341907135|0.121212121212121
GO:0004872
F:receptor activity|30|1|0.0978404737025427|0.0303030303030303
GO:0043565
F:sequence-specific DNA binding|15|1|0.14740508533612|0.0303030303030303
GO:0003723
F:RNA binding|20|2|1.3042842215256|0.0606060606060606
GO:0016563
F:transcription activator activity|5|1|2.62152560083595|0.0303030303030303
GO:0005634
C:nucleus|118|5|0.0256312983723854|0.151515151515152
GO:0005739
C:mitochondrion|27|2|0.483735438677967|0.0606060606060606
GO:0005886
C:plasma membrane|62|2|0.23946877001382|0.0606060606060606
GO:0005856
C:cytoskeleton|16|1|0.101381922675026|0.0303030303030303
GO:0016607
C:nuclear speck|4|2|18.1517659352142|0.0606060606060606
GO:0016323
C:basolateral plasma membrane|2|1|9.07588296760711|0.0303030303030303
GO:0006955
P:immune response|18|2|1.70146522698247|0.0606060606060606
GO:0045087
P:innate immune response|13|2|3.35163089783779|0.0606060606060606
GO:0008026
F:ATP-dependent helicase activity|6|1|1.93471960989202|0.0303030303030303
GO:0004842
F:ubiquitin-protein ligase activity|4|1|3.67449320794148|0.0303030303030303
GO:0043204
C:perikaryon|2|1|9.07588296760711|0.0303030303030303
GO:0005923
C:tight junction|6|1|1.93471960989202|0.0303030303030303
GO:0008360
P:regulation of cell shape|8|1|1.1103500522466|0.0303030303030303
GO:0007050
P:cell cycle arrest|4|1|3.67449320794148|0.0303030303030303
GO:0030170
F:pyridoxal phosphate binding|2|1|9.07588296760711|0.0303030303030303
GO:0030424
C:axon|5|1|2.62152560083595|0.0303030303030303
GO:0007005
P:mitochondrion organization|2|1|9.07588296760711|0.0303030303030303
GO:0016491
F:oxidoreductase activity|4|1|3.67449320794148|0.0303030303030303
GO:0006508
P:proteolysis|19|1|0.0211274267172634|0.0303030303030303
GO:0006916
P:anti-apoptosis|6|1|1.93471960989202|0.0303030303030303
GO:0043154
P:negative regulation of caspase activity|3|1|5.45978404737025|0.0303030303030303
GO:0008201
F:heparin binding|5|1|2.62152560083595|0.0303030303030303
GO:0016481
P:negative regulation of transcription|5|1|2.62152560083595|0.0303030303030303
GO:0050896
P:response to stimulus|5|1|2.62152560083595|0.0303030303030303
GO:0001942
P:hair follicle development|2|1|9.07588296760711|0.0303030303030303
GO:0004252
F:serine-type endopeptidase activity|6|1|1.93471960989202|0.0303030303030303
GO:0005096
F:GTPase activator activity|3|1|5.45978404737025|0.0303030303030303
GO:0006958
P:complement activation, classical pathway|4|1|3.67449320794148|0.0303030303030303
GO:0009058
P:biosynthetic process|2|1|9.07588296760711|0.0303030303030303
GO:0001836
P:release of cytochrome c from
mitochondria|3|1|5.45978404737025|0.0303030303030303
GO:0007224
GO:0051902
P:smoothened signaling pathway|2|1|9.07588296760711|0.0303030303030303
P:negative regulation of mitochondrial
depola...|1|1|20.0152142110763|0.0303030303030303
GO:0008218
P:bioluminescence|1|1|20.0152142110763|0.0303030303030303
GO:0018298
P:protein-chromophore linkage|1|1|20.0152142110763|0.0303030303030303
GO:0008299
P:isoprenoid biosynthetic process|2|2|40.0304284221526|0.0606060606060606
GO:0045941
P:positive regulation of transcription|1|1|20.0152142110763|0.0303030303030303
GO:0048739
P:cardiac muscle fiber development|1|1|20.0152142110763|0.0303030303030303
GO:0045216
P:cell-cell junction organization|1|1|20.0152142110763|0.0303030303030303
GO:0060044
P:negative regulation of cardiac muscle
cell ...|1|1|20.0152142110763|0.0303030303030303
GO:0022010
P:myelination in the central nervous system|1|1|20.0152142110763|0.0303030303030303
GO:0031643
P:positive regulation of myelination|1|1|20.0152142110763|0.0303030303030303
GO:0045893
P:positive regulation of transcription,
DNA-d...|2|1|9.07588296760711|0.0303030303030303
GO:0043687
P:post-translational protein modification|1|1|20.0152142110763|0.0303030303030303
GO:0051246
P:regulation of protein metabolic process|1|1|20.0152142110763|0.0303030303030303
GO:0002230
GO:0032727
GO:0032728
P:positive regulation of defense response
to ...|1|1|20.0152142110763|0.0303030303030303
P:positive regulation of interferon-alpha
pro...|1|1|20.0152142110763|0.0303030303030303
P:positive regulation of interferon-beta
prod...|2|1|9.07588296760711|0.0303030303030303
GO:0016310
P:phosphorylation|1|1|20.0152142110763|0.0303030303030303
GO:0016266
P:O-glycan processing|1|1|20.0152142110763|0.0303030303030303
GO:0006103
P:2-oxoglutarate metabolic process|1|1|20.0152142110763|0.0303030303030303
GO:0042851
P:L-alanine metabolic process|1|1|20.0152142110763|0.0303030303030303
GO:0060716
GO:0004310
P:labyrinthine layer blood vessel
development|1|1|20.0152142110763|0.0303030303030303
F:farnesyl-diphosphate farnesyltransferase
ac...|1|1|20.0152142110763|0.0303030303030303
GO:0004496
F:mevalonate kinase activity|1|1|20.0152142110763|0.0303030303030303
GO:0001730
F:2'-5'-oligoadenylate synthetase activity|1|1|20.0152142110763|0.0303030303030303
GO:0035252
F:UDP-xylosyltransferase activity|1|1|20.0152142110763|0.0303030303030303
GO:0004021
GO:0003854
GO:0047012
F:L-alanine:2-oxoglutarate aminotransferase
a...|1|1|20.0152142110763|0.0303030303030303
F:3-beta-hydroxy-delta5-steroid
dehydrogenase...|1|1|20.0152142110763|0.0303030303030303
F:sterol-4-alpha-carboxylate
3-dehydrogenase ...|1|1|20.0152142110763|0.0303030303030303
GO:0005591
C:collagen type VIII|1|1|20.0152142110763|0.0303030303030303
GO:0005912
C:adherens junction|1|1|20.0152142110763|0.0303030303030303
13:
0.6288
10
Lrp1, Esd, Tpt1p, Ly6c1, Gstm1, Mgst1, Gas6, Hmox1, Gsta4, Lamp2
GO:0055114
GO:0005509
GO:0005576
GO:0005737
GO:0016021
GO:0005792
GO:0008152
GO:0007275
GO:0004872
GO:0005783
GO:0005634
GO:0005886
GO:0005743
GO:0005905
GO:0031225
GO:0006749
GO:0005624
GO:0010008
P:oxidation reduction|42|1|0.305500821018062|0.1
F:calcium ion binding|39|2|3.9738284703802|0.2
C:extracellular region|45|1|0.231800766283525|0.1
C:cytoplasm|100|2|0.279310344827586|0.2
C:integral to membrane|175|2|0.070935960591133|0.2
C:microsome|11|2|22.5153605015674|0.2
P:metabolic process|9|2|28.3463601532567|0.2
P:multicellular organismal development|14|1|3.37167487684729|0.1
F:receptor activity|30|1|0.830459770114943|0.1
C:endoplasmic reticulum|12|2|20.332183908046|0.2
C:nucleus|118|1|0.241992986557569|0.1
C:plasma membrane|62|3|5.3793659621802|0.3
C:mitochondrial inner membrane|6|1|10.166091954023|0.1
C:coated pit|5|1|12.5689655172414|0.1
C:anchored to membrane|4|1|16.1801724137931|0.1
P:glutathione metabolic process|2|1|34.2775862068966|0.1
C:membrane fraction|10|1|5.38793103448276|0.1
C:endosome membrane|4|1|16.1801724137931|0.1
GO:0005765
GO:0040008
GO:0030670
GO:0004091
GO:0004364
GO:0005741
GO:0016023
GO:0043277
GO:0030178
GO:0010875
GO:0032429
GO:0018738
GO:0004392
GO:0005770
C:lysosomal membrane|3|1|22.2080459770115|0.1
P:regulation of growth|4|1|16.1801724137931|0.1
C:phagocytic vesicle membrane|4|1|16.1801724137931|0.1
F:carboxylesterase activity|2|1|34.2775862068966|0.1
F:glutathione transferase activity|4|3|157.180172413793|0.3
C:mitochondrial outer membrane|2|1|34.2775862068966|0.1
C:cytoplasmic membrane-bounded vesicle|3|1|22.2080459770115|0.1
P:apoptotic cell clearance|1|1|70.5137931034483|0.1
P:negative regulation of Wnt receptor signali...|1|1|70.5137931034483|0.1
P:positive regulation of cholesterol efflux|1|1|70.5137931034483|0.1
P:regulation of phospholipase A2 activity|1|1|70.5137931034483|0.1
F:S-formylglutathione hydrolase activity|1|1|70.5137931034483|0.1
F:heme oxygenase (decyclizing) activity|1|1|70.5137931034483|0.1
C:late endosome|1|1|70.5137931034483|0.1
17:
0.5558
34
Orc2, Tuba4a, Ptgs2, Mettl13, Nuf2, Vash2, Dtl, Txnrd1, Dhx33, Ncapg2, Emb, Cdhr1, Enpp2,
Parvb, Tuba1c, Rps10, Fosl1, Slc20a1, Stau1, Car13, Hspa4l, B3galnt1, Npnt, Ctnnbip1, Peg10,
Pik3c2a, Mrgprf, Tacc1, Osgin1, Agt, Col12a1, Pcolce2, Abcd1, Prkx
GO:0007155
GO:0055114
P:cell adhesion|23|2|0.787060587353382|0.0588235294117647
P:oxidation reduction|42|2|0.00046749734376509|0.0588235294117647
GO:0006810
GO:0001516
GO:0007156
GO:0030154
GO:0005515
GO:0005044
GO:0050660
GO:0005509
GO:0020037
GO:0005178
GO:0005198
GO:0005615
GO:0016020
GO:0005576
GO:0005737
GO:0016021
GO:0005789
GO:0005604
GO:0005792
GO:0005829
GO:0008152
GO:0016055
GO:0006915
GO:0007160
GO:0016042
GO:0001658
GO:0045944
GO:0007049
GO:0007165
GO:0007275
GO:0007186
GO:0008217
GO:0030198
GO:0003700
GO:0003677
GO:0005525
GO:0008270
GO:0046872
GO:0005524
GO:0004872
P:transport|10|1|0.60131845841785|0.0294117647058824
P:prostaglandin biosynthetic process|2|1|8.75555780933063|0.0294117647058824
P:homophilic cell adhesion|8|1|1.04061359026369|0.0294117647058824
P:cell differentiation|20|3|4.53351926977688|0.0882352941176471
F:protein binding|105|5|0.00116874335941274|0.147058823529412
F:scavenger receptor activity|5|1|2.49918864097363|0.0294117647058824
F:FAD binding|6|1|1.83530087897228|0.0294117647058824
F:calcium ion binding|39|2|0.0159941748582722|0.0588235294117647
F:heme binding|7|1|1.37449434946392|0.0294117647058824
F:integrin binding|5|1|2.49918864097363|0.0294117647058824
F:structural molecule activity|6|3|26.2666734279919|0.0882352941176471
C:extracellular space|27|1|0.0559672451356021|0.0294117647058824
C:membrane|21|1|0.000233748671882545|0.0294117647058824
C:extracellular region|45|2|0.00576966418751411|0.0588235294117647
C:cytoplasm|100|6|0.366125760649087|0.176470588235294
C:integral to membrane|175|5|1.2531150391191|0.147058823529412
C:endoplasmic reticulum membrane|26|1|0.039446091433921|0.0294117647058824
C:basement membrane|6|1|1.83530087897228|0.0294117647058824
C:microsome|11|2|4.26987276415268|0.0588235294117647
C:cytosol|24|2|0.679438810006761|0.0588235294117647
P:metabolic process|9|1|0.791350011268875|0.0294117647058824
P:Wnt receptor signaling pathway|9|1|0.791350011268875|0.0294117647058824
P:apoptosis|14|1|0.17966096783541|0.0294117647058824
P:cell-matrix adhesion|9|2|5.89919314852378|0.0588235294117647
P:lipid catabolic process|5|1|2.49918864097363|0.0294117647058824
P:branching involved in ureteric bud
morphoge...|5|2|13.2933062880325|0.0588235294117647
P:positive regulation of transcription from
R...|4|1|3.51846855983773|0.0294117647058824
P:cell cycle|9|1|0.791350011268875|0.0294117647058824
P:signal transduction|35|2|0.078354100260794|0.0588235294117647
P:multicellular organismal
development|14|1|0.17966096783541|0.0294117647058824
P:G-protein coupled receptor protein
signalin...|8|1|1.04061359026369|0.0294117647058824
P:regulation of blood pressure|3|1|5.24853279242732|0.0294117647058824
P:extracellular matrix organization|8|2|7.03693711967546|0.0588235294117647
F:transcription factor activity|32|1|0.167049949290061|0.0294117647058824
F:DNA binding|30|1|0.117680865449628|0.0294117647058824
F:GTP binding|22|2|0.908729485524617|0.0588235294117647
F:zinc ion binding|80|2|0.81790060851927|0.0588235294117647
F:metal ion binding|27|1|0.0559672451356021|0.0294117647058824
F:ATP binding|78|5|0.492395589535549|0.147058823529412
F:receptor activity|30|2|0.250033806626099|0.0588235294117647
GO:0043565
GO:0003924
GO:0004867
GO:0016563
GO:0003725
GO:0005634
GO:0005739
GO:0005886
GO:0000139
GO:0005856
GO:0031965
GO:0005730
GO:0005840
GO:0030308
GO:0006935
GO:0006955
GO:0006974
GO:0003779
GO:0047391
GO:0003676
GO:0030247
GO:0008026
GO:0016702
GO:0004930
GO:0005794
GO:0005887
GO:0008283
GO:0050661
GO:0043065
GO:0006260
GO:0006979
GO:0043524
GO:0042493
GO:0045454
GO:0007067
GO:0008083
GO:0001707
GO:0030216
GO:0008285
F:sequence-specific DNA binding|15|1|0.125016903313049|0.0294117647058824
F:GTPase activity|12|2|3.67060175794456|0.0588235294117647
F:serine-type endopeptidase inhibitor
activity|7|1|1.37449434946392|0.0294117647058824
F:transcription activator activity|5|1|2.49918864097363|0.0294117647058824
F:double-stranded RNA binding|5|1|2.49918864097363|0.0294117647058824
C:nucleus|118|9|2.17113108949015|0.264705882352941
C:mitochondrion|27|2|0.425248290887236|0.0588235294117647
C:plasma membrane|62|2|0.283297781849113|0.0588235294117647
C:Golgi membrane|13|1|0.249926665626463|0.0294117647058824
C:cytoskeleton|16|1|0.083065415821501|0.0294117647058824
C:nuclear membrane|5|1|2.49918864097363|0.0294117647058824
C:nucleolus|13|1|0.249926665626463|0.0294117647058824
C:ribosome|2|1|8.75555780933063|0.0294117647058824
P:negative regulation of cell growth|2|1|8.75555780933063|0.0294117647058824
P:chemotaxis|5|1|2.49918864097363|0.0294117647058824
P:immune response|18|1|0.0287784539102998|0.0294117647058824
P:response to DNA damage stimulus|4|1|3.51846855983773|0.0294117647058824
F:actin binding|12|1|0.339719405003381|0.0294117647058824
F:alkylglycerophosphoethanolamine
phosphodies...|2|1|8.75555780933063|0.0294117647058824
F:nucleic acid binding|8|2|7.03693711967546|0.0588235294117647
F:polysaccharide binding|2|1|8.75555780933063|0.0294117647058824
F:ATP-dependent helicase activity|6|1|1.83530087897228|0.0294117647058824
F:oxidoreductase activity, acting on single
d...|3|1|5.24853279242732|0.0294117647058824
F:G-protein coupled receptor activity|9|1|0.791350011268875|0.0294117647058824
C:Golgi apparatus|7|1|1.37449434946392|0.0294117647058824
C:integral to plasma membrane|12|1|0.339719405003381|0.0294117647058824
P:cell proliferation|7|2|8.5131498116488|0.0588235294117647
F:NADP or NADPH binding|4|1|3.51846855983773|0.0294117647058824
P:positive regulation of apoptosis|5|1|2.49918864097363|0.0294117647058824
P:DNA replication|9|2|5.89919314852378|0.0588235294117647
P:response to oxidative stress|8|1|1.04061359026369|0.0294117647058824
P:negative regulation of neuron
apoptosis|2|1|8.75555780933063|0.0294117647058824
P:response to drug|2|1|8.75555780933063|0.0294117647058824
P:cell redox homeostasis|7|1|1.37449434946392|0.0294117647058824
P:mitosis|4|2|17.5111156186613|0.0588235294117647
F:growth factor activity|9|1|0.791350011268875|0.0294117647058824
P:mesoderm formation|4|1|3.51846855983773|0.0294117647058824
P:keratinocyte differentiation|3|1|5.24853279242732|0.0294117647058824
P:negative regulation of cell
proliferation|6|2|10.4970655848546|0.0588235294117647
GO:0008201
GO:0004791
GO:0016887
GO:0005874
GO:0010811
GO:0006486
GO:0050896
GO:0046983
GO:0019904
GO:0006730
GO:0006468
GO:0042542
GO:0030511
GO:0007018
GO:0004089
GO:0004674
GO:0005942
GO:0048015
GO:0034097
GO:0051301
GO:0006986
GO:0030432
GO:0009409
GO:0005791
GO:0051258
GO:0042640
GO:0030261
GO:0001833
GO:0045494
GO:0007565
GO:0007612
GO:0045787
GO:0051591
GO:0051412
GO:0009629
GO:0009612
GO:0014070
GO:0032570
GO:0006817
GO:0008298
GO:0006457
F:heparin binding|5|1|2.49918864097363|0.0294117647058824
F:thioredoxin-disulfide reductase
activity|3|1|5.24853279242732|0.0294117647058824
F:ATPase activity|5|1|2.49918864097363|0.0294117647058824
C:microtubule|5|2|13.2933062880325|0.0588235294117647
P:positive regulation of cell-substrate
adhesion|3|1|5.24853279242732|0.0294117647058824
P:protein amino acid glycosylation|4|1|3.51846855983773|0.0294117647058824
P:response to stimulus|5|1|2.49918864097363|0.0294117647058824
F:protein dimerization activity|7|1|1.37449434946392|0.0294117647058824
F:protein domain specific binding|2|1|8.75555780933063|0.0294117647058824
P:one-carbon metabolic process|4|1|3.51846855983773|0.0294117647058824
P:protein amino acid phosphorylation|11|1|0.454364742762309|0.0294117647058824
P:response to hydrogen peroxide|2|1|8.75555780933063|0.0294117647058824
P:positive regulation of transforming
growth ...|2|1|8.75555780933063|0.0294117647058824
P:microtubule-based movement|3|2|24.572062204192|0.0588235294117647
F:carbonate dehydratase activity|2|1|8.75555780933063|0.0294117647058824
F:protein serine/threonine kinase activity|7|1|1.37449434946392|0.0294117647058824
C:phosphoinositide 3-kinase complex|2|1|8.75555780933063|0.0294117647058824
P:phosphoinositide-mediated signaling|2|1|8.75555780933063|0.0294117647058824
P:response to cytokine stimulus|2|1|8.75555780933063|0.0294117647058824
P:cell division|6|3|26.2666734279919|0.0882352941176471
P:response to unfolded protein|3|1|5.24853279242732|0.0294117647058824
P:peristalsis|2|1|8.75555780933063|0.0294117647058824
P:response to cold|2|1|8.75555780933063|0.0294117647058824
C:rough endoplasmic reticulum|2|1|8.75555780933063|0.0294117647058824
P:protein polymerization|2|2|38.7408519269777|0.0588235294117647
P:anagen|1|1|19.3704259634888|0.0294117647058824
P:chromosome condensation|1|1|19.3704259634888|0.0294117647058824
P:inner cell mass cell proliferation|2|1|8.75555780933063|0.0294117647058824
P:photoreceptor cell maintenance|1|1|19.3704259634888|0.0294117647058824
P:female pregnancy|1|1|19.3704259634888|0.0294117647058824
P:learning|1|1|19.3704259634888|0.0294117647058824
P:positive regulation of cell cycle|1|1|19.3704259634888|0.0294117647058824
P:response to cAMP|1|1|19.3704259634888|0.0294117647058824
P:response to corticosterone stimulus|1|1|19.3704259634888|0.0294117647058824
P:response to gravity|1|1|19.3704259634888|0.0294117647058824
P:response to mechanical stimulus|1|1|19.3704259634888|0.0294117647058824
P:response to organic cyclic substance|1|1|19.3704259634888|0.0294117647058824
P:response to progesterone stimulus|1|1|19.3704259634888|0.0294117647058824
P:phosphate transport|1|1|19.3704259634888|0.0294117647058824
P:intracellular mRNA localization|1|1|19.3704259634888|0.0294117647058824
P:protein folding|2|1|8.75555780933063|0.0294117647058824
GO:0009312
GO:0001890
GO:0007154
GO:0046854
GO:0021987
GO:0022027
GO:0000226
GO:0022008
GO:0032886
GO:0001998
GO:0048143
GO:0001568
GO:0002035
GO:0042756
GO:0008065
GO:0042445
GO:0001822
GO:0001543
GO:0045723
GO:0043410
GO:0040018
GO:0046622
GO:0002019
GO:0001999
GO:0002018
GO:0009651
GO:0051145
GO:0048659
GO:0003688
GO:0004601
GO:0004666
GO:0008168
GO:0005315
GO:0047273
P:oligosaccharide biosynthetic process|1|1|19.3704259634888|0.0294117647058824
P:placenta development|1|1|19.3704259634888|0.0294117647058824
P:cell communication|1|1|19.3704259634888|0.0294117647058824
P:phosphoinositide phosphorylation|1|1|19.3704259634888|0.0294117647058824
P:cerebral cortex development|1|1|19.3704259634888|0.0294117647058824
P:interkinetic nuclear migration|1|1|19.3704259634888|0.0294117647058824
P:microtubule cytoskeleton organization|1|1|19.3704259634888|0.0294117647058824
P:neurogenesis|1|1|19.3704259634888|0.0294117647058824
P:regulation of microtubule-based
process|1|1|19.3704259634888|0.0294117647058824
P:angiotensin mediated vasoconstriction
invol...|1|1|19.3704259634888|0.0294117647058824
P:astrocyte activation|1|1|19.3704259634888|0.0294117647058824
P:blood vessel development|2|1|8.75555780933063|0.0294117647058824
P:brain renin-angiotensin system|1|1|19.3704259634888|0.0294117647058824
P:drinking behavior|1|1|19.3704259634888|0.0294117647058824
P:establishment of blood-nerve barrier|1|1|19.3704259634888|0.0294117647058824
P:hormone metabolic process|1|1|19.3704259634888|0.0294117647058824
P:kidney development|1|1|19.3704259634888|0.0294117647058824
P:ovarian follicle rupture|1|1|19.3704259634888|0.0294117647058824
P:positive regulation of fatty acid
biosynthe...|1|1|19.3704259634888|0.0294117647058824
P:positive regulation of MAPKKK
cascade|1|1|19.3704259634888|0.0294117647058824
P:positive regulation of multicellular
organi...|1|1|19.3704259634888|0.0294117647058824
P:positive regulation of organ growth|1|1|19.3704259634888|0.0294117647058824
P:regulation of renal output by
angiotensin|1|1|19.3704259634888|0.0294117647058824
P:renal response to blood flow during
renin-a...|1|1|19.3704259634888|0.0294117647058824
P:renin-angiotensin regulation of
aldosterone...|1|1|19.3704259634888|0.0294117647058824
P:response to salt stress|1|1|19.3704259634888|0.0294117647058824
P:smooth muscle cell differentiation|1|1|19.3704259634888|0.0294117647058824
P:smooth muscle cell proliferation|1|1|19.3704259634888|0.0294117647058824
F:DNA replication origin binding|1|1|19.3704259634888|0.0294117647058824
F:peroxidase activity|1|1|19.3704259634888|0.0294117647058824
F:prostaglandin-endoperoxide synthase
activity|1|1|19.3704259634888|0.0294117647058824
F:methyltransferase activity|1|1|19.3704259634888|0.0294117647058824
F:inorganic phosphate transmembrane
transport...|1|1|19.3704259634888|0.0294117647058824
F:galactosylgalactosylglucosylceramide
GO:0008499
GO:0016303
GO:0035005
GO:0035091
GO:0031702
GO:0031703
GO:0000792
GO:0000939
GO:0005664
GO:0000777
GO:0031262
GO:0005925
GO:0042734
GO:0019717
GO:0030529
GO:0030136
GO:0005815
GO:0005778
beta-D...|1|1|19.3704259634888|0.0294117647058824
F:UDP-galactose:beta-N-acetylglucosamine
beta...|1|1|19.3704259634888|0.0294117647058824
F:1-phosphatidylinositol-3-kinase
activity|1|1|19.3704259634888|0.0294117647058824
F:phosphatidylinositol-4-phosphate 3-kinase
a...|1|1|19.3704259634888|0.0294117647058824
F:phosphoinositide binding|1|1|19.3704259634888|0.0294117647058824
F:type 1 angiotensin receptor binding|1|1|19.3704259634888|0.0294117647058824
F:type 2 angiotensin receptor binding|1|1|19.3704259634888|0.0294117647058824
C:heterochromatin|1|1|19.3704259634888|0.0294117647058824
C:inner kinetochore of condensed
chromosome|1|1|19.3704259634888|0.0294117647058824
C:nuclear origin of replication recognition
c...|1|1|19.3704259634888|0.0294117647058824
C:condensed chromosome kinetochore|1|1|19.3704259634888|0.0294117647058824
C:Ndc80 complex|1|1|19.3704259634888|0.0294117647058824
C:focal adhesion|2|1|8.75555780933063|0.0294117647058824
C:presynaptic membrane|1|1|19.3704259634888|0.0294117647058824
C:synaptosome|1|1|19.3704259634888|0.0294117647058824
C:ribonucleoprotein complex|1|1|19.3704259634888|0.0294117647058824
C:clathrin-coated vesicle|1|1|19.3704259634888|0.0294117647058824
C:microtubule organizing center|1|1|19.3704259634888|0.0294117647058824
C:peroxisomal membrane|1|1|19.3704259634888|0.0294117647058824
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