Download CURRICULUM VITAE Ruth Freeman, M.D.

CURRICULUM VITAE
Ruth Freeman, M.D.
_______________________________________________________
Academic Rank:
Professor of Obstetrics, Gynecology and Women‟s Health
Professor of Medicine
Albert Einstein College of Medicine
Home Address:
130 Lovell Road
New Rochelle, New York 10804
(914) 632-5180
Business Address:
Montefiore Medical Center
Dept. of Ob/Gyn and Women‟s Health
Division of Reproductive Endocrinology
1695 Eastchester Road, Suite 301
Bronx, New York 10461
Telephone: (718) 405-8152 Fax: (718) 405-8154
E-mail: [email protected]
Medical License #:
086861-1
Citizenship:
United States
Education:
1956
1960
B.A., Hunter College, CUNY
M.D., Albert Einstein College of Medicine
Postgraduate Training:
1960-61
1961-62
1962-63
1963-64
1963-64
1964-65
1965-67
Internship - Maimonides Hospital
Assistant Resident in Medicine
Flower Fifth Avenue Hospital - New York Medical College
Assistant Resident in Medicine
Montefiore Hospital - Bronx, New York
Resident in Endocrinology
New York Medical College
(Research Work: Immunoassay of Insulin)
Course in Radioisotopes, Mt. Sinai Hospital
NIH Fellowship in Endocrinology
Mt. Sinai Medical Center, New York City
Research– Measurement of Testosterone by Gas Chromatography
NIH Fellowship in Endocrinology
Emory University, Atlanta, Ga.
Research - Isolation of Prolactin from Human Pituitaries
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Postgraduate Training (Con’t)
1998
Certified Clinical Densitometrist (C.C.D.)
Certified by the International Society for Clinical Densitometry
March 2, 1998, Recertified 8/2001, 7/2004
Professional Employment and Hospital Appointments:
1967
1967-72
1967-72
1969
1970
1971 - 1984
1972-Present
1975
1987
1991
Instructor in Medicine and Gynecology/Obstetrics
Albert Einstein College of Medicine
Director of Endocrinology - Dept of Medicine, Lincoln Hospital, NY
Assistant Attending Physician in Medicine & Obstetrics & Gynecology
Bronx Municipal Hospital Center, Lincoln Hospital and the Hospital of
the Albert Einstein College of Medicine, NY
Associate, Departments of Medicine and Obstetrics & Gynecology
Assistant Professor of Medicine, Assistant Professor of Ob/Gyn
Albert Einstein College of Medicine, NY
Director of Endocrinology - Department of Obstetrics & Gynecology,
Albert Einstein College of Medicine, Bronx, New York
Attending Physician in Medicine and Obstetrics & Gynecology
Bronx Municipal Hospital Center
Weiler Hospital of the Albert Einstein College of Medicine
Montefiore Hospital
Associate Professor - Department of Obstetrics & Gynecology
And Department of Medicine
Professor - Department of OB/GYN & Women‟s Health
Albert Einstein College of Medicine, Bronx, New York
Professor - Department of Medicine, Albert Einstein College of
Medicine, Bronx, New York
Board Certification:
1967
1972
American Board of Internal Medicine
American Board of Internal Medicine
Subspecialty in Endocrinology and Metabolism
Professional Society Membership:
Endocrine Society
American Medical Society
North American Menopause Society
Association for Bone & Mineral Research
American Association of Clinical Endocrinology
American College of Physicians
International Society for Clinical Densitometry
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Awards and Honors:
1956
1973
1975
1996
1997
2000
2006
Phi Beta Kappa
Alumni Member Alpha Omega Alpha Society
Leo M. Davidoff Society
Fellow American College of Physicians
Fellow American College of Clinical Endocrinology
Samuel Rosen Award for Clinical Teaching
Lifetime Service Award, Almuni Association AECOM
Other Professional Activities:
1976
1976-1985
1979-1991
1980 (Jul/Aug)
1983 (4/14-15)
1984-2000
1984-present
1985-present
1990-present
1992, December
19931994-1998
1998-2000
19992000-2001
20012001-2005
2005
2009
2010
Consultant, Gynecological Endocrine. Bronx Lebanon Hospital, Bx, NY
Women's Liaison Officer to Association of American Medical
Colleges for the Albert Einstein College of Medicine
Course Leader of Core Endocrine Physiology/Pathophysiology Course
2nd Year Curriculum, Albert Einstein College of Medicine
Visiting Professor - Shaare Zedek Hospital, Jerusalem, Israel
Visiting Professor - Department of Medicine and Obstetrics &
Gynecology - Kansas City School of Medicine of the Univ. of Missouri
Member of Ethics Committee for New Reproductive Technologies
Member of Human Use Radioisotope Committee
Member of Institutional Review Board for Human Research
Director, Bone Densitometry Unit, Montefiore Medical Center,
Department of Obstetrics and Gynecology and Women‟s Health
Visiting Professor - Department of Medicine, Infertility Research
Unit - Massachusetts General Hospital, Boston, Mass.
Director Menopause Research & Treatment Center, Institute of
Women's Health, Montefiore, Albert Einstein College Medicine.
Scientific Program Committee – NAMS Annual Meeting
Member, Committee on Appointments to Full Professorial Level
Albert Einstein College of Medicine
Editorial Board – Menopause
Scientific Committee for NAMS 2002 National Meeting
Coordinator-YU High School for Girls Summer Research Program
Endocrine Society Student Affairs Committee
NAMS – Professional Education Committee
Chair of NAMS Abstract Committee
Committee on Appointment to Full Professor
Invited Participation At National Meetings:
1990
International Congress of Bone Densitometry - Ferrara, Italy –
March 1990 "The Use of Hormones to Prevent Osteoporosis"
1993
International Congress of Bone Densitometry - Ferrara, Italy – April
1993, “The Role of Progestins in the Prevention of Postmenopausal
Osteoporosis”.
Symposium on Lab Diagnosis of Human Fertility (Speaker) Amer
Assoc for Clinical Chemistry - Dec 1993 "Laboratory Testing in the
Diagnosis of Hormonal Infertility"
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Invited Participation At National Meetings (Con’t):
1994
1998
2000
2001/02/03
2001
2002
2003
2004
2005
2008
2010
Workshop - "Progestins - Choice of Drug & Effect on Bone"
North American Menopause Society - 4th Annual Meeting
San Diego, California
Autumn in New York, Roundtable "Hormone Replacement Therapy"
Workshop - "Micronutrients"
North American Menopause Society - 5th Annual Meeting
Washington, DC
North American Menopause Society–Organizer/Speaker Workshop
on Skin & Hair. Toronto, Canada, September
Therapeutic Options for Menopausal Health meeting- Tucson, AZ,
February 13-15
Chair & Course Director at World Congress on
Osteoporosis-Chicago, IL, June
Chair - Alumni Science Day, June
Chair – Endocrine Society Meeting, Denver, Colorado, June
Controversies in Osteoporosis
NAMS-Annual Meeting-Symposium – Osteoporosis, New Orleans,
October
Lecture-Hormone Replacement Therapy
Where do we go from here?
Course Director 06/01-06/02
Chair – NAMS – Symposium on Sleep; Chicago, IL, October
Reunion Medical Conference- The Alumni Association Albert Einstein
College of Medicine, Course Director, June 4.
American Chemical Society – National Meeting & Exposition Program“A Physician‟s Review of New Therapies and Products for Women‟s
Needs”, New York, NY September 8, 2003.
ISCD Meeting, New Orleans, February 16-19.
AACE Meeting, Boston, April 28-30.
Endocrine Society Meeting, Virginia, September 10-12.
16th Annual Meeting North American Menopause Society, San
Diego, CA, Sept 30 “The Science of Progestins in Hormone
Therapy”
Symposia – “Menopause and Andropause”, Washington,DC, Convention
Center, July 27-31, 2008.
Director Scientific Conference 50th Reunion – AECOM
Invited Lecturer (recent years only)
1999
2000
New Hampshire Conference of Women‟s Health
March Lecture: Women & Heart Disease
Our Lady of Mercy Hospital Grand Rounds, April
Lecture - Hormone Replacement Therapy
Victory Memorial Hospital Grand Rounds - November
Coronary Artery Disease in Women
“Controversies regarding Hormone Therapy, Update”
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2001
2002
2003
2004
2005
2006
2007
Beth Israel Hospital - April
“Metabolic Consequences of Polycystic Ovarian Syndrome”Beth Israel Hospital - May
The Clinical Use of Bone Densitometry - St. Barnabas - August
“New Treatment for Osteoporosis”
Hackensack Medical Center – October
Lenox Hill Grand Rounds-April
“Polycystic Ovarian Syndrome”
Vassar Hospital Grand Rounds – September
“An Update on Estrogen/Progesterone”
Einstein Women‟s Day – September
Mid-State Medical Center Grand Rounds – October
“An Update on Estrogen/Progesterone”
New York Medical College – November
“Women‟s Health Initiative – Update”
Jamaica Hospital Grand Rounds – January
“Polycystic Ovarian Syndrome”
Brookdale Hospital Grand Rounds – February
“Treatment of Menopause – WHI and Beyond”
Women‟s Medical Association Dinner, Norwalk, CT
“Osteoporosis” February 11, 2004
Phelps Memorial Hospital Grand Rounds-Sleepy Hollow, NY
“HRT” April 2, 2004
Nassau University Medical Center, East Meadow, NY
“Osteoporosis” August 31, 2004
NY Methodist Hospital, Park Slope, Brooklyn
“HRT” December 1, 2004
Riverdale Jewish Center for Women
“Menopause”, March 2, 2005
Amer. Assoc. Univ. Women,Chappaqua, NY “Osteoporosis”, April 6,
2005
Jack D. Weiler Hospital, Rheumatology Grand Rounds,
“Osteoporosis”, May 6, 2005
Jack D. Weiler Hospital, Degenerative Spine Course, “Osteoporosis”
October 16, 2005
Student Women‟s Health Journal Club – Albert Einstein College of
Medicine, Bronx, NY, “Calcium and Vitamin D”, March 22, 2006
Grand Rounds, Bronx Lebanon Hospital, “Osteoporosis”, March 2
Grand Rounds, St, Vincent‟s Hospital, Bridgeport, CT, “Efficacy of
Different HRTs”, June 13, 2006
Grand Rounds, Beth Israel Hospital, New York, NY, “Vitamin D and
Bone Density and Osteoporosis”, October 3, 2006
Jack D. Weiler Hospital, Degenerative Spine Course, “Osteoporosis”
October 29, 2006.
Grand Rounds, Beth Israel Hospital, New York, NY. “Osteoporosis”
April 20, 2007.
Montefiore
Medical
Center,
Degenerative
Spine
Course,
“Osteoporosis” October 28, 2007.
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2009
2009-10
Jack D. Weiler Hospital, Noontime Conference, Dept. of Medicine.
“Osteoporosis” November 20, 2007.
Grand Rounds, Jack D. Weiler Hospital, Dept. of OB/GYN,
“Osteoporosis” December 4, 2007.
Grand Rounds, “Osteoporosis” Winthrop Hospital, March 6, 2009.
Monthly Lectures Osteoporosis. Jacobi Medical Center.
Internal Medicine Residents.
Original Communications in Reviewed Journals:
1.
Futterweit W, Freeman R, Siegel GL and Griboff SI: Clinical Applications of a Gas
Chromatographic Method for the Combined Determination of Testosterone and Epitestosterone
Glucuronide in Urine. J. Clin. Endocrinol. 25:11, 1965
2. Futterweit W, Freeman R, Siegel GL and Griboff SI: Measurement of Urinary Testosterone
and Epitestosterone Glucuronide as a Test of Gonadal Reserve. Fertil. Steril. 18:659, 1967.
3. Kapan, S, Boyar R, Freeman R, Frantz A, Hellman L, Weitzman ED: Twenty-four hour Secretory
Patterns of Gonadotropins and Prolactin in a Case of Chiari Frommel Syndrome. J Clin Endocrinol
Metab 90:234, 1975.
4. Friedman G, Freeman R, Bookchin R, Boyar R, Murthy G and Hellman L: Testicular Function in
Sickle Cell Disease. Fertil. Steril. 24:l0l8, 1974.
5. Freeman R, Lev-Gur M, Boyar R, and Schulman H: Studies of Maternal Plasma Prolactin and
Amniotic Fluid Prolactin. Obs. Gynecol. 47:282, 1976.
6. Mortimer RH, Fleischer N, Lev-Gur M and Freeman R: Correlation between Integrated LH and
FSH Levels and the Response to Luteinizing Hormone Releasing Factor (LRF). J. Clin. Endocrinol.
Metab. 43:1240, 1976.
7. Goldman JM, Matz R, Mortimer R and Freeman R: Extreme Elevations of Creatinine
Phosphokinase in Hypothyroidism with Isoenzyme Analysis. JAMA 237:325, 1977
8. Mortimer R, Lev-Gur M, Freeman R and Fleischer N: Pituitary Response to Bolus and Continuous
Intravenous Infusion of Luteinizing Hormone - Releasing Factor in Normal Women and in Women
With Polycystic Ovarian Syndrome. Am. J. Obstet. Gynecol. 130:630-634, 1978.
9. Shangold M, Freeman R, Thysen B and Gatz M: The Relationship Between Long-Distance
Running, Plasma Progesterone and Luteal Phase Length. Fertil. Steril. 31:130, 1979.
10. Shangold M, Freeman R, Kumaresan P, Feder AS and Vasicka A: Plasma Oxytocin Concentrations
in a Pregnant Woman with Total Vasopressin Deficiency. Obstet. Gynecol. 61:662, 1983.
11. Thysen B. Gatz M, Freeman R, Alpert BE and Charytan C: Serum Thyroid Hormone Levels in
Patients on Continuous Ambulatory Peritoneal Dialysis and Regular Hemodialysis. Nephron 33:49,
1983.
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Original Communications in Reviewed Journals (Con’t):
12. Zumoff B, Freeman R, Coupey S, Saenger P, Markowitz M and Kream J: A Chronobiologic
Abnormality in Luteinizing Hormone Secretion in Teenage Girls With The Polycystic Ovary
Syndrome. N. Eng. J. Med. 309:l206-1209, 1983.
13. Freeman R, Lev-Gur M, Koslowe R, Schulman H and Gatz M: Maternal Plasma and Amniotic Fluid
Levels of Estradiol, Estrone, Progesterone and Prolactin in Early Pregnancy. Obstet, Gynecol.
63:4, 507-5l0, 1984.
14. Freeman R: In Vitro Fertilization and Extrauterine Pregnancy ("Test Tube" Baby). Mt. Sinai
Jnl. Med. 5l:l, p.3-6, 1984.
15. Freeman R, Rosen H and Thysen B: The Incidence of Thyroid Dysfunction in Unselected
Postpartum Population. Arch. Int. Med. 146:1361, 1986.
16. Freeman R, Duvivier R, Barad DH, Weller R: The Effect of Depot medroxy-progesterone
Acetate vs Oral Conjugated Estrogens on Cholesterol, Lipoprotein Cholesterol and Triglycerides
in Postmenopausal Women. Multidisciplinary Perspectives on Menopause. Ann NY Acad Sci
592:419-21, l989.
17. Rosen H and Freeman R: Two Unusual Cases of Hyperthyroidism Following Hypothyroidism.
Einstein Quarterly Jnl. 7:#4 p.142, Fall 1989.
18. Freeman R: Estrogen Therapy to Prevent Osteoporosis. Pandora, Giornale Di Ricera Clinica e
Diagnostica, Anno 2-Nl, pg. 33-36, Med Sys S.p.a., Genova, Italy. Feb. 1990.
19. Schneyer AL, Sluss PM, Whitcomb RW, Hall JE, Crowley WF and Freeman R: Development of a
Radioligand Receptor Assay (RRA) for Measuring Follitropin in Serum. Clin. Chem. 37:508-514,
1991.
20. Freeman R, Wezenter B, Silverstein M, Kuo D, Weiss KL, Kantrowitz AB, Schubart UK:
Pregnancy-associated Subacute Hemorrhage into a Prolactinoma Resulting in Diabetes Insipidus.
Fertil & Steril. 58:2, p. 427-429, Aug. 1992.
21. Freeman R and Benedict A: The Effect of an Aquatic Exercise on Aged Person's Bone Density,
Body Image, and Morale. Activities, Adaptation & Aging, 17:3, 1993
22. Freeman R: The Role of Progestins in the Prevention of Postmenopausal Osteoporosis: Giornale
Di Ricera Clinica e Diagnostica, Anno 6 Suppl. 1, pg. 73-75, Medical Systems S.p.a., Genova, Italy.
Jan.-April 1994.
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Original Communications in Reviewed Journals (Con’t):
23. Schwartz J, Freeman R, Frishman W: Clinical Pharmacology of Estrogens: Focus on Their
Cardiovascular Actions and Cardioprotective Benefits of Replacement Therapy in
Postmenopausal Women. J Clin Pharmacol 35:314-329, 1995.
24. Freeman R: Hormones and Heart Disease.
1996.
Menopause Management 5:2, p. 10-12, May/June
25. Mukherjee T, Barad D, Turk and Freeman R: A Randomized, Placebo-Controlled Study on the
Effect of Cyclic Intermittent Etidronate Therapy on the Bone Mineral Density Changes
Associated with Six Months of Gonadotropin-Releasing Hormone Agonist Treatment. Am J
Obstet Gynecol 175:1, p. 105-109, July 1996.
26. Freeman R: The Management of the Patient with Osteoporosis - A Modern Epidemic.
American Journal of Managed Care. 4:S97-S109, 1998.
The
27. Freeman R: Hormone Replacement Therapy (Estrogen and Progesterone): Is it Necessary for
Heart Disease Prevention? Preventive Cardiology, 2000;3:21-23.32.
28. Freeman R: An Update on Osteoporosis, Its Diagnosis, Management and Treatment. The Female
Patient, 2000; September 2000 Supplement pg 4-10.
29. J. Christopher Gallagher, MD, David J. Baylink, MD, Freeman R, Michael McClung, MD:
Prevention of Bone Loss with Tibolone in Postmenopausal Women: Results of Two Randomized,
Double-Blind, Placebo-Controlled, Dose-Finding Studies. Journal of Clinical Endocrinology &
Metabolism, 2001; vol 86(10): pp.4717-4726.
30. Freeman R. Hot Flashes: Prescription Alternatives to ERT/HRT. The Female Patient, April
2001, Vol. 26, No.4.
31. Kripke DF, Brunner R, Freeman R, Hendrix S. Jackson RD, Masaki K, Carter RA. Sleep
complaints of postmenopausal women. Clinical Journal of Women‟s Health, December 2001;Vol. 1,
No. 5.
32. Berliner JI, Rybicki AC, Kaplan RC, Monrad ES, Freeman R, Billett HH: Elevated levels of Factor
XI are Associated with Cardiovascular Disease in Women. Thromb Res. 2002 Jul 15;107(12):55-60.
33. Ilercil A, Freeman R, Lachmann J, Brofferio A, Scotton M, Freitag A, Emerson M, LeJemtel
TH, Shirani J: Relation of Baseline Forearm Vasodilator Reserve to Vascular Endothelial
Response to Estrogen Replacement Therapy in Healthy Postmenopausal Women. The Am J of
Cardiol. 2002 Sep 1; 89(9):1139-41.
34. Espeland M, Rapp S, Shumaker S, Brunner R, Manson J, Sherwin B, Hsia J, Margolis K, Hogan P,
Wallace R, Dailey M, Freeman R, Hays J. Conjugated equine Estrogens and Global Cognitive
Function in Postmenopausal Women. Women‟s Health Initiative Memory Study. JAMA, 2004
June 23;291(24):2959-68.
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Original Communications in Reviewed Journals (Con’t)
35. Fang J, Freeman R, Jeganathan R, Alderman MH. Variations in Hip Fracture Hospitalization
Rate Among Different Race/Ethnicity Groups in New York City. Ethn Dis.
2004
Spring:14(2):280-4.
36. Mulligan K, Anastos K, Justman J, Freeman R, T, Wichienkuer P, Robison E, Hessol N. Fat
Distribution in HIV-infected Women in The USA: DEXA Substudy in the Women‟s Interagency
HIV Study. J Acquir Immune Defic Syndr. 2005 Jan 1;38(1):18-22.
37. Arnsten JH, Freeman R, Howard AA, Floris-Moore M, Santoro N, Schoenbaum E. HIV
Infection and Bone Mineral Density in Middle-Aged Women. Clin Infect Dis. 2006 Apr
1;42(7);1014-20. ; 42: Epub 2006 Feb 24.
38. Arsten JH, Freeman R, Howard AA, Floris-Moore M, Lo Y, Klein R. Decreased Bone Mineral
Density and Increased Fracture Risk in Aging Men With or at Risk for HIV Infection. AIDS
2007, 21:617-623.
39. Pal L, Norian J, Zeitilan G, Bowen S, Adel G, Freeman R, Santoro N. Vasomotor Symptoms in
Infertile Premenopausal Women: A Hitherto Unappreciated Risk for Low Bone Mineral Density.
Fertil and Steril, 2008 Nov,90(5):1626-34. Epub 2008 Feb 20.
40. Pal L, Hailpern SM, Santoro NF, Freeman R, Barad D, Kipersztok, S, Barnbei VM, WassertheilSmoller S. Association of Pelvic Organ Prolapse and Fractures in Postmenopausal Women:
Analysis of Baseline Data from WHI‟s Initiative Estrogen Plus Progestin Trial. Menopause,Epub
8/9/2007.
41. Anastos K, Lu D, Shi Q, Mulligan K, Tien PC, Freeman R, Cohen MH, Justman J, Hessol N. The
Association of Bone Mineral Density with HIV Infection and Antiretrovirol Treatment In
Women. Antiviral Therapy, 9/07.
42. Wactawski-Wende J, LieLing W, Nelson W, Tylavsky, Freeman R, Hendrix S, Jackson R. Low
Fat Dietary Pattern, Fractures and Bone Mineral Density: The WHI‟s Dietary Modification
Clinical Trial. Archives of Internal Medicine 2/08.
43. McTieman A, Wactawski-Wende J, Wu L, Rodabouth R, Watts NB, Tylavsky F, Freeman R,
Hendrix S, Jackson R. Low Fat, Increased Fruit, Vegetable, and Grain Dietary Pattern,
Fractures, and Bone Mineral Density: The Women‟s Health Initiative Dietary Modification
Trial. Am J of Clin Nutr 2009;89: 1864-76.
44. Norian JM, Zeitlian G, Adel G, Freeman R, Santoro N, Pal L. Low Serum Osteoprotegerin Levels
in Premenopausal Infertile Women with Low Bone Density: An Association of Relevance?
Fertility and Sterility, Vol. 91, No. 2, February 2009.
45. Freeman R, Pollack R, Rosenbloom E. Assessing Impaired Glucose Tolerance and Insulin
Resistance in Polycystic Ovarian Syndrome with a Muffin Test: An Alternative to the Glucose
Tolerance Test. Endocrine Practice. Vol. 16, No. 5, September/October 2010.
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Original Communications in Reviewed Journals (Con’t)
46. Freeman R. Management Strategies for Osteoporosis and Osteopenia. Contemporary OB/GYN.
November 2010. Volume 55, Number 11.
47. Pal L, Hailpern SM, Santoro N, Freeman R, Barad D, Kipersztok S, Barnabei VM, WassertheilSmoller S. Increased Incident Hip Fractures in Postmenopausal Women with Moderate-toSevere Pelvic Organ Prolapse. Accepted for publication in Menopause 2011.
48. Wolff E, Pal L, Altun T, Madankumar R, Freeman R, Amin H, Harman M, Santoro N, Taylor HS.
Skin Wrinkles and rigidity in Early Postmenopausal Women Vary by Race/Ethnicity: Baseline
Characteristics of the Skin Ancillary Study of the KEEPS Trial. Fertility and Sterility, Vol. 95,
No. 2, February 2011.
49. Sharma A, Cohen HW, Freeman R, Santoro N, Schoenbaum EE. Prospective Evaluation of Bone
Mineral Density among Middle-Aged HIV-Infected and Uninfected Women: Association
between Methadone Use and Bone Loss. Maturitas 70 (2011) 295-301.
50. Traub M, Jain A, Maslow B-S, Pal L, Stein D, Santoro N, Freeman R. The „Muffin Test‟ – An
Alternative to Oral Glucose Tolerance Test (OGTT) to Detect Impaired Glucose Tolerance
(IGT). Menopause, Vol. 19, No. 1 2012.
Books, Chapters in Books, Review Articles; Other Publications:
1.
Futterweit W, Freeman R, Siegel GL, Griboff SI, Dorfman RI and Soffer LJ: Contribution to
Workshop on Gas Chromatography of Steroids. Arlie House, Warrenton, VA, Feb. 25-27, 1965.
M.B. Lipsett Ed, Plenum Press, NY pg. 19-22.
2. Freeman R: Chapter on Ovary, In: Nuclear Medicine in Endocrinology. B.Rothfeld, Ed.
Lippincott. Philadelphia, PA: July 1978, pg. 100-110
J.B.
3. Freeman R: Medical Diseases and Infertility. Chapter in Infertility and Reproductive Medicine,
Clinics of North America, Workup of the Infertile Woman. D.H. Barad, Ed. W.B. Saunders Co.,
2:2, pg.419-428, April 1991.
4. Gomberg-Maitland M, Frishman WH, Karch S, Schwartz J, Freeman R, and Shapiro J:
Hormones as Cardiovascular Drugs: Estrogens, Progestins, Thyroxine, Growth Hormone,
Corticosteroids, and Testosterone.
Chapter in Cardiovascular Pharmacotherapeutics. In
Frishman WH, Sonnenblick EH (eds), McGraw Hill, NY 1997.
5. Freeman R: Response to question for the International Correspondence Society of
Obstetricians & Gynecologists Collected Letters. Vol.38 No.2, February 1997.
6. Richards ML, Carter SM, Gross SJ, Freeman R. Multiple Endocrine Neoplasia, Type 2. Emed,
Inc. Medicine: On-line Medical Reference, 1st Edition (2000). Emed Online Textbooks, Ed.
Steven Altschuler et al. Emedicine.com, Inc. <http://www.emedicine.com/MED/index.shtml.
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Books, Chapters in Books, Review Articles; Other Publications (Con’t):
7. Freeman R: Editorial- Effect of Weight Change on Cardiovascular Risk Factors Menopause
Sept. 2001
8. Freeman R:
Comments for Web pages NAMS Prescription Alternatives to HRT for
Management of Menopausal Flushes.
9. Freeman R: Article – “Osteoporosis - A Problem for Women of All Ages”, Viewpoints, Vol. 16,
No. 2,, January 2003 (National Council of Jewish Women Newsletter).
10. Freeman R, Lewis RM. The therapeutic role of estrogens in postmenopausal women. Endocrinol
Metab Clin North Am 2004 Dec;33(4):771-89. Review.
11. Chervenak JL, Freeman R, Jones J. Hormone Therapy for the Postmenopausal Women:
Balancing Benefits Versus Risks. The Female Patient Supplement, June 2005.
12. Freeman R. The Science of Progestogen in Hormone Therapy. Accepted for publication in a
supplement to Menopause Management. Mar/Apr, Vol. 14, Number 2, Pg. 32.
13. Freeman R. The Pattern of Hair after Menopause. Article in NAMS “Menopause Matters”
column in The Female Patient. March 2006.
14. Freeman R. Comment Column in NAMS “First to Know” e-newsletter. October 30, 2006.
15. Freeman R. Editorial: Are Blood Glucose Levels Affected by Menopause. Menopause-The
Journal of The North American Menopause Society, Volume 14(3), May/June 2007.
16. Freeman R. Vitamin D: The Sunshine Hormone. How and When to Treat Deficiencies. Article
in American Society for Reproductive Medicine - Menopausal Medicine, May 2009, Volume 17,
Number 2, S8-S11.
17. Freeman R. Comment Column (Estrogen and Coronary Artery Disease) in NAMS “First to Know”
e-newsletter. October 28, 2009.
18. Freeman R. Changes in Hair Growth Patterns in Postmenopausal Women. The Female Patient.
Vol. 34, October 2009.
19. Freeman R. Menopause e-Consult. Management Issue of 60 year old patient with low bone
density. Vol. 6, Issue 3, July 2010.
20. Freeman R. Skeletal Implications of Reproductive Aging. Article in Seminars in Reproductive
Medicine, Volume 28, Number 5, 422-425, September 2010.
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Abstracts:
1.
Freeman R: The Purification and Further Separation of Prolactin from Human Pituitary
Extracts. Medical House Staff and Fellows Research Projects Program, Emory University
School of Medicine, pg. 14, 1966.
2. Freeman R: The Extraction of Prolactin from Postpartum Blood. Medical House Staff and
Fellows Research Projects Program, pg.16 1967.
3. Freeman R and Wilhelmi AE: The Further Purification of Human Prolactin. Program of the 51st
Meeting of the Endocrine Society, pp.44, 1969.
4. Shangold MM, Freeman R: An ovulation As A Cause of Primary Amenorrhea. Presented at the
IX World Congress of Fertility & Sterility, Hosted by the American Fertility Society & the
International Federation of Fertility Societies, Miami, FL, Apr 1977.
5. Coupey SM, Hein K, Freeman R and Fleckman A: Adolescent Polycystic Ovarian Syndrome.
Presented at Society for Adolescent Medicine Annual Research Meeting, San Francisco, CA,
Oct. 1979.
6. Coupey SM, Freeman RG, Zumoff G and Hein K: Desynchronization of Luteinizing Hormone (LH)
from Sleep in Adolescents with Polycystic Ovary Syndrome (PCOS). Presented at Society for
Pediatric Research, Abs. #8, Vol. 15:4 Pt. 11 pp.441, 1980.
7. Feld LG, Freeman R, Werner M, Thysen B, Greifer I, Weiss R: Reproductive Function in Chronic
Renal Failure in Adolescent Females. Presented at American Society of Nephrology Meeting,
Chicago IL, Dec. 1982.
8. Freeman R, Galler M, Feld L, Thysen B: Menstrual Cycle Hormone Levels in Women with Chronic
Renal Failure on Hemodialysis or Chronic Ambulatory Peritoneal Dialysis (CAPD). Presented at
Annual Meeting of the Endocrine Society, San Antonio, TX, June 1983.
9. Freeman R: Therapy of Menopause Related Problems. Presented at American Association for
Clinical Chemistry Symposium, New York City, July 29, 1983.
10. Feld LG, Freeman R, Werner M, Thysen B, Weiss RA: Reproductive Function in Adolescent
Females with Chronic Renal Failure. 6th Intl. Symposium of Ped. Nephrology, Hanover, Aug 1983.
11. Freeman R, Jackanicz TM, Buffong E, Thysen B: Long Term Use of Vaginal Ring Containing
Estradiol for Replacement Therapy. Presented at Endocrine Society, Anaheim, CA., June 1986.
12. Feinman M, Barad DH, Hailparn T, Cohen BL, Barg P, Freeman R: The Use of Parenteral
Estradiol Valerate in a Donor Oocyte Program. Presented at VI World Congress on In Vitro
Fertilization and Alternate Assisted Reproduction. Jerusalem, Israel, April 1989.
13. Barad DH, Freeman R, Speranza M, Damiano A, Feinman M: Effect of Dietary Fat on
Absorption of Micronized Estradiol. Presented at 71st Annual Meetings - Endocrine Society,
Seattle WA, 1989.
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Abstracts (Con’t):
14. Freeman R, Small M, Thornhill B, Barad DH: The Effect of Smoking on Bone Density in Women
with Premature Ovarian Failure vs Normal Women. Poster presentation at 46th Annual Meet of
the Amer. Fert. Society, Wash. DC, Oct. 1990.
15. Palan PR, Freeman R, Basu J and Romney SL: Effects of Estrogen Replacement Therapy on
Serum Antioxidant Levels in Postmenopausal Women. Presented at Annual Meetings of Society
for Gynecologic Investigation, 1990.
16. Palan PR, Freeman R, Basu J, Romney SL: Effects of Estrogen Replacement Therapy on Serum
B-Carotene and Vitamin E Levels in Postmenopausal Women. Poster Presentation at 73rd Annual
Meeting of The Endocrine Society, Washington, DC, June 1991.
17. Freeman R: 24 Hour Blood Pressure Measurement in Postmenopausal Women Before and After
One Year of Estrogen Replacement Therapy. Presented at 2nd Annual Meeting of North
American Menopause Society, Montreal, Canada, Sept. 1991.
18. Freeman R: Short Luteal Phase as a Cause of Primary Infertility in Well Controlled Insulin
Dependent Diabetic Women. Presented as poster at 47th Annual Meetings of The American
Fertility Society, Orlando, FL., Oct. 1991.
19. Freeman R, Benedict A, Barad D: The Effect of Swimming on Bone Density of Women Aged 6085. Presented at Annual Meeting of North American Menopause Society, Cleveland, Ohio, Sept.
1992.
20. Freeman R, Haberman S, Thornhill B, Barad D: Vertebral Bone Density is Reduced by Smoking,
but not by Hyperprolactinemia. Presented at the 48 th Annual Meeting of American Fertility
Society, New Orleans, La., Nov. 1992.
21. Freeman R, Palan PR, Romney SL: Alterations in Serum Beta-Carotene and Retinol Levels by
Estrogen Replacement Therapy in Postmenopausal Women. Presented at the International
Menopause Society Meeting, Stockholm, Sweden 1993.
22. Freeman R, Benedict A, Barad D: Effect of Swimming on Bone Density of Elderly Men.
Presented at the Endocrine Society Meeting, Anaheim, CA, June 1993.
23. Freeman R, Mukherjee T, Turk R, Barad D: Comparison of DEXA Bone Density in Women with
Endometriosis or Leiomyomata. Presented at 40th Annual Meeting of Society for Gynecologic
Investigation, Toronto, Canada, March 1994.
24. Freeman R, Ramirez P, Barad DH: Influence of Dietary Fat on the Absorption of Micronized
Estradiol. Presented at the Endocrine Society Meeting, Anaheim, CA, June 1994.
25. Freeman R, Mukherjee T, Turk R, Barad D: The Effect of Etidronate on the Bone Loss
Associated with the Long Term GN-RH Agonist Therapy. Presented Soc. for Gynecologic
Invest., Mar 1994.
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Abstracts (Con’t):
26. Freeman R, Lennox S, Ellenberg J.: Estrogen vs. Imipramine in the Treatment of Depression in
Menopausal Women. Presented at the 5th Annual Meeting of the North American Menopause
Society, Washington, DC, September 1994.
27. Freeman R, Schwalb T, Barad DH: Ambulatory Blood Pressure Before and After Estrogen
Replacement Therapy with Premarin or Estraderm Patches. Presented at 50th Annual Meeting
of the American Fertility Society, Texas, November 1994.
28. Freeman R, Thornhill B, Barad DH: Smoking Decreases Bone Density in Premenopausal Women
but not in Postmenopausal Women. Presented at the 50th Annual Meeting of the American
Fertility Society, Texas, November 1994.
29. Freeman R, Lennox S, Ellenberg J: The Level of Depression Seen in New Patients at a
Menopause Center as Determined by Zung Depression Scale. Presented at the North American
Menopause Society Meeting, San Francisco, CA, September 1995.
30. Freeman R, Chen D: Gonadotropin Dependent Virilization in Postmenopausal Women. Presented
at the North American Menopause Society Meeting, Sept. 1995.
31. Freeman R, Javed A, Branovan Z, Huang Y, Barad D: Smoking Reduces BMD in Women Who Have
Bb or bb But Not BB Variant of Vitamin D Receptor Gene. Presented at the Endocrine Society
Meeting, San Francisco, June 1996.
32. Buchbinder SS, Hibbard CA, Kessler M, Alster R, Freeman R: Mammographic Changes
Associated with Long-Term Hormonal Replacement Therapy. Presented to American Roentgen
Ray Society, Boston, May 1997 meeting.
33. Buchbinder S, Freeman R, Kader K, Jan K: Mammographic Self Selective Bias in NIH Funded
(WHI) Mammograms. Presented to the Society of Breast Imaging, San Diego, 1997.
34. Buchbinder S, Hibbard CA, Kessler M, Alster R, Freeman R:
Mammographic Findings
Associated with Mode of Estrogen Replacement Therapy Society of Breast Imaging, San Diego,
1997.
35. Freeman R, Rogoff E, Lisker G, Thysen B: Elevated Parathyroid Hormone Levels in Subjects
Who Have Low Bone Density and Normocalcemia. Presented at the North American Menopause
Society Meeting, Boston, September 1997.
36. R Freeman, J Terrana, E Rogoff, G Lisker: The Effect of Treatment on Bone Density and
Parathyroid Hormone Levels in Normocalcemic Hyperparathyroidism. Presented at the
Endocrine Society Meeting, New Orleans, June 1998.
37. J.C. Gallagher, R. Freeman, D.J. Baylink, MA Bolognese. SL. Bonnick, R.D. Emkey, M.W.
Grenwalk. M.W. Laton, M.R.McClung. Tibolone Prevents Postmenopausal Bone Loss and Is WellTolerated: Phase III Trial Results. Society for Bone and Mineral Research, 1999 Program &
Abstracts, September 1999.
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Abstracts (Con’t):
38. A.C. Freitag2, Strizik B, Stein E, Monrad ES, Lerrick K, Freeman R: Women with - have
different risk profiles depending on years since menopause. Presented at Endocrine Society
Meetings, San Diego, Calif June 1999.
39. Freeman R, Wiggan R. MacFadden DV, P.Lekaj. The Menopause Monitor: Validation of a new
home urine test for the diagnosis of menopause presented at the 11 th Meeting of North
American Menopause Society Orlando Fl, September 2000.
40. Ilercil A, Kholdarova L, Lachman JS, Freitag AC, Emerson M, Freeman R, Shirani J: Left
Ventricular Diastolic Function is Related to Aortic Compliance and Brachial Artery Endothelial
Dependent Vasodilation in Normal Postmenopausal Women. Am J Geriatric Cardiol 2000; 9 (2):
110.
41. Ilercil A, Lachmann J, Lekaj P, Freitag A, Emerson M, Freeman R, Shirani J: Increased
Brachial Artery Diameter and Flow Reserve with Estrogen Replacement Therapy in Healthy
Postmenopausal Women. Circulation 2000; 102 (18): II-838
42. Ilercil A, Freeman R, Lachmann J, Scotton M, Lekaj P, Freitag A, Emerson M, Shirani J:
Baseline Forearm Vasodilator Reserve Determines Beneficial Effects of Estrogen on Endothelial
Function in Healthy Postmenopausal Women. Am J Geriatric Cardiol 2001; 10 (2): 123.
43. Arnsten JH, Freeman R, Santoro N, Kunins H, Schoenbaum EE. Bone mineral density and
protease inhibitor use in older HIV-infected women. Program & Abstracts of the 9 th Conf. on
Retroviruses and Opportunistic Infections; Feb. 24-28, 2002; Seattle WA (poster).
44. Ilercil A, Brofferio A, Fedorovitch M, Freeman R, Shirani J: Marked Variation in EndothelialDependent Brachial Artery Dilation Among Healthy Postmenopausal Women. Am J Geriatric
Cardiol 2002; 11 (2): 138.
45. Ilercil A, Brofferio A, Fedorovitch M, Freeman R, Shirani J: Nitroglycerin-mediated Brachial
Artery Dilation is Related to Plasma FSH in Healthy Postmenopausal Women. Am J Geriatric
Cardiol 2002; 11 (2) 138.
46. Freeman R, Naini A, Shanske S, DiMauro S, Shanske A. Hypogonadism in familial cerebellar
ataxia with muscle coenzyme Q10 deficiency. Presented at the American Society of Human
Genetics, Baltimore, MD, September 2002.
47. Arnsten JH, Freeman R, Santoro N, Schoenbaum EE. HIV infection and protese inhibitor use
are not associated with reduced mineral density in older HIV-infected women. Program &
Abstracts the 10th Annual Conference on Retroviruses and Opportunistic Infections; February
10-14, 2003.
48. Howard AA, Freeman R, Santoro N, Schoenbaum EE. Body Composition and Antiretroviral Use
in Older HIV-Infected Women. Presented at the 10 th Conference on Retroviruses and
Opportunistic Infections, Boston, February 2003.
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Ruth Freeman, M.D.
Abstracts (Con’t):
49. Mulligan K, Anastos K, Justman J, Freeman R, Wichienkuer P, Robison E, Hessol N. Fat
Distribution in HIV-Infected Women in the United States: DEXA Substudy in the Women‟s
Interagency HIV Study. Presented at the 5 th International Workshop on Adverse Drug
Reactions and Lipodystrophy in HIV, Paris, July 2003, (Antiviral Therapy 8:l14, 2003).
50. Anastos K, Shi Q, Mulligan K, Cai X, Justman J, Freeman R, Danoff A, Robison E, Wichienkuer P,
Williams T, Hessol N. The Association of Bone Mineral Density (BMD) with HIV Infection and
Antiretrovirol Treatment In Women. 11th Conference on Retroviruses and Opportunistic
Infections, San Francisco, CA, February 2004.
51. Chervenak J, Freeman R. Climara® 0.0375 mg/d May Provide Smoother Transition From Oral
Estrogen Therapy Than Vivelle Dot 0.05 mg/d. Presented at the 15 th Annual Meeting of the
North American Menopause Society, Washington, DC, September 6-9, 2004.
52. Gopalakrishnan G, Buono D, Budner N, Howard AA, Floris-Moore M, Lo Y, Freeman R, Arnsten J,
Santoro N, Schoenbaum E. Impact of HIV on Menstrual Patterns and Bone Mineral Density.
Poster Presentation at Conference on Retroviruses and Opportunistic Infections, August 2006.
53. Pal L, Hailpern S, Santoro N, Barad D, Freeman R, Barnabei V, Kipersztok S, Smoller S. Pelvic
Organ Prolapse: A Sinister Marker for Fragility Fracture: Baseline Data from the Women‟s
Health Initiative Estrogen and Progesterone (EP) Trial. Presented at 2006 SGI Annual
Scientific Meeting.
54. Pal L, Norian J, Hailpern SH, Zeitilan G, Bowen S, Adel G, Freeman R, Santoro N. Bone Density
(BMD) and bone turnover are influenced by Ovarian Reserve (OR) in premenopausal women.
Presented at Endocrine Society Meeting, Boston, Mass., June 2006.
55. Klein R, Lo Y, Freeman R, Arnsten J. A Prospective Study of Fracture Rates in Older Men with
or at Risk for HIV Infection. Poster presentation. XVI International AIDS Conference,
August 2006.
56. Freeman R, Atzmon G, Stampfer D, Barzilai N. Longevity is Associated with Fewer Offspring,
but Not Later Menopause.
Poster presented at 17 th Annual NAMS Meeting, Nashville, Tenn.,
October 2006.
57. Norian J, Zeitlian G, Adel G, Freeman R, Santoro N, Pal L. Serum Osteoprotegerin Levels are
Predictive of Bone Mineral Density in Premenopausal Infertile Women. Abstract presented at
ASBMR Meeting, Philadelphia, PA, September 2006.
58. Pal L, Freeman R. Vasomotor Symptoms in Regularly Cycling Premenopausal Infertile Women:
heretofore Unappreciated Indicators of Low Bone Mineral Density. Society for Reproductive
Endocrinology and Infertility, October 2006.
59. Freeman R, Pal L, Rosenbaum SB. The Relationship of Vitamin D Levels, BMI, vitamin intake and
LDL Cholesterol with Bone Density in Patients of an Endocrine Practice. Presented at the
Vitamin D Conf. of Amer. Society for Bone and Mineral Research, Arlington, VA, Dec. 2006.
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Ruth Freeman, M.D.
Abstracts (Con’t):
60. Henderson VW, Espeland MA, Hogan PE, Rapp SR, Stefanick ML, Wactawski-Wende J, Johnson
KC, Wassertheil-Smoller S, Freeman R, Curb D. Prior Use of Hormone Therapy and Incident
Alzheimer‟s Disease in The Women‟s Health Initiative Memory Study. Neurology 68 (supple. 1):
A205, 2007. Abstract presented at the annual American Academy of Neurology Meeting in
Boston, May 2007.
61. Pal L, Freeman R, Santoro NF. Relationship Between Serum Creatinine and BMD: Positive
Correlations with BMD in Premenopausal Women. Presented at the 89 th Annual Endocrine
Society Meeting, Toronto, Canada, June 2-5, 2007.
62. Coker LH, Byran NR, Kuller LH, Hogan PE, Baird AE, Bettermann K, Freeman R, Lao Z, Margolis
KL, Stefanick ML, Wallace RB, Shumaker SA. Effects of Postmenopausal Hormone Therapy on
Volumetric Sub-Clinical Cerebrovascular Disease: The Women‟s Health Initiative Memory Study
– Magnetic Resonance Imaging Study (WHIMS-MRI).
Presented at the International
Conference on Prevention of Dementia, Washington, DC, June 9-12, 2007,
63. Tomuta N, Davis N, Tomuta V, Isasi C, Wylie-Rosett J, Freeman R. Comparison of LowCarbohydrate Diet to Low-Fat Diet on Body Composition in Overweight and Obese Individuals
with T2DM. Poster Presentation at the NAASO Meeting in New Orleans, October 2007.
64. Madaukumar R, Pal L, Freeman R, Amin H, Isaac B, Magnani M, Figueroa A, Alemany L, Santoro
N. Comprehension of risks and benefits of hormone replacement therapy responses to informed
consent questionnaires from the Kronos Early Estrogen Prevention Study (KEEPS). Presented at
Society for Gynecologic Investigation Annual Meeting, San Diego, CA, March 2008.
65. Traub ML, Jain A, Pal L, Stein DT, Santoro N, Freeman R. The Use of a Muffin Test to
Diagnose Impaired Glucose Tolerance in Large Cohort Studies and It‟s Correlation with OGTT
and FBG. Presented at the 90th Annual Endocrine Meeting, June 15, 2008, San Francisco, CA.
66. Sharma A, Cohen HW, Freeman R, Santoro N, Schoenbaum EE. Prospective Evaluation of Bone
Mineral Density Among Middle-Aged HIV-Infected and Uninfected Women.
Poster
presentation at the 16th Conference on Retroviruses and Opportunistic Infections (CROI),
February 8-11, 2009, Montreal, Canada.
67. Freeman R, Chervenak J, Samanta M. Which Vertebrae Should be Included in Reporting Spine
Bone Density by DEXA? Presented at the ISCD Meeting, March 11-14, 2009, Orlando, FL.
68. Mogul HR, Freeman R, Tanenbaum K, Klein Lee Ann, Williams-Cleaves B, Cruikshank G, Frey M,
Greenbaum R, Johnson K, Jozak S, Samanta M. EMPOWIR: Enhance the Metabolic Profile of
Women with Insulin Resistance: Carbohydrate Modified Diet Alone and in Combination with
Metformin or Metformin Plus Rosiglitazone in Nondiabetic Women with Midlife Weight Gain and
Documented Insulin Elevateions (Syndrome W). Assessment of the Dietary Intervention in 40
Study Subjects. Presented at the 27th Annual Obesity Society Meeting. Washington, DC.
October 24-28, 2009.
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Ruth Freeman, M.D.
Abstracts (Con’t):
69. Santoro N, Segal-Isaacson CJ, Freeman R, Weinerman S, Ongseng F, Zeitman G, Cruikshank G,
Gibbs K, Paik L, Kupperman E. Bone Density Losses Associated with Diet and Hormone Changes
After Bariatric Surgery in a Multi-Racial, Multi-Ethnic Population. Presented at the 27 th Annual
Obesity Society Meeting, Washington, DC. October 24-28, 2009.
70. Mogul H, Freeman R, Klein L, Williams-Cleaves B, Cruikshank D, Frey M, Greenbaum R, Jozak S,
Samanta M, Tanenbaum K. Weight Reduction with a Novel Carbohydrate Modified Diet in 58
Study Subjects in the EMPOWIR Trial. Presented at the Endocrine Meeting, June 19-22, 2010,
San Diego.
71. Pal L, Santoro N, Taylor H, Wolff E, Freeman R. Skin Wrinkling and Rigidity are Predictive of
Bone Mineral Density in Early Postmenopausal Women. Poster Presentation at Endocrine
Society Meeting. June 4-7, 2011, Boston, MA.
72. Anand R, Freeman R. Mogul H. Free T4 Levels Correlate with Fat Mass in Obese, Euthyroid
Women. Presented at the Endocrine Society Meeting. June 4-7, 2011, Boston, MA.
73. Mogul HR, Freeman R, Frey M, Greenbaum R, Jozak S, Klein L, Tanenbaum K. CarbohydrateModified Diet and Insulin-Sensitizing Medications Reduce Body Weight and Fasting Insulin in
the EMPOWIR (Enhance the Metabolic Profile of Women with Insulin Resistance) Trial.
Presented at the Endocrine Society Meeting. June 4-7, 2011, Boston, MA.
Research Funding
1994 - 1996
1995 - 2006
1995 – 1997
1995 - 1997
1997 - 1999
1998 - 1999
1999 - 2000
1999 - 2002
Principal Investigator - Organon Inc. (Tibolone)
Co-Investigator. Women's Health Initiative.
P.I.: Dr. Sylvia Wassertheil Smoller
Adjudicator for Health Outcomes
Principal Investigator - Rhone Poulenc Rorer
E2/Northethisterone Patches.
Principal Investigator. R.W. Johnson.
Cyclophasic Hormone Therapy
Principal Investigator
Organon, Inc., The Efficacy and Safety of Tibolone (Org OD14) in
Prevention of Osteoporosis in Postmenopausal Women
Principal Investigator
Eli Lilly, A Randomized Double Blind Controlled Trial of Fluxetine
HC1 for Treating Vasomotor Instability in Symptomatic PMP Women.
Investigator, Organon, Open, Cross Over, 2 Center, Study Compare
Single Subcutaneous Administration Follistim & Oral Clomiphene
Citrate Treatment for Anovulationy Chronic Anovulator Infertile
Women.
Principal Investigator, Parke Davis - Effects of FemHRT (DI376) In
Perimenopausal Women: A 6- Month Randomized, Double Blind
Placebo Controlled, Parallel Group, Multicenter Study
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Ruth Freeman, M.D.
1999 - 2003
1999 - 2001
2000
2001
2004
2005
2006
2009
2010
Principal Investigator, Parke Davis-Pfizer - Beyond Endorsed Lipids
Lowering with EBCT Scanning (Belles).
Principal Investigator, Pfizer.
Effect of FemHrt on Vascular
Reactivity
Principal Investigator Wyeth Pharmaceuticals – Comparison of
Bazedoxifene to Placebo & Raloxifene
Principal Investigator – Proctor & Gamble – ($65,000)
Principal Investigator–Eli
Lilly
“Comparison of Raloxifene
Alendronate”
Principal Investigator, Roche Laboratories– A prospective, openlabel, multicenter study to evaluate the change in bone turnover
marker for once monthly oral ibandronate therapy in treatment
naïve postmenopausal osteoporosis patients.
Co-Principal Investigator, KEEPS Study (Kronos Early Estrogen
Prevention Study)
Principal Investigator, Roche a randomized, double-blind, placebo
controlled study to determine time to onset of the bone
resorption marker, sCTX with once-monthly ibandronate in the
treatment of postmenopausal osteoporosis
Principal Investigator – Boehringer Ingelheim – A 24 week,
randomized, double-blind, placebo-controlled, safety and efficacy
trial of filbanserin 50 and 100 milligrams each evening in
premenopausal women with hypoactive sexual desire disorder.
Principal Investigator – GlaxoSmithKline - EMPOWIR
Principal Investigator – Boehringer Ingelheim – A twelve month, open
label, safety trial of Flibanserin 50 mg to 100 mgs daily in women
with hypoactive sexual desire disorder.
Principal Investigator – Boehringer Ingelheim – A 24 week,
randomized, double-blind, placebo-controlled, safety and efficacy
trial of Flibanserin with up titration, 100 mgs administered orally
once daily in naturally postmenopausal women with hypoactive sexual
desire disorder.
KEEPS Breast Study Mammographic Density and Breast Health
Ancillary Study – Principal Investigator.
Reproductive Endocrine Fellows
1971-1972
1972-1973
1974-1976
1976-1978
1978-1979
19791980-1983
1983-1984
1984-1986
1986-1987
1997-1999
Dr.
Dr.
Dr.
Dr.
Dr.
Dr.
Dr.
Dr.
Dr.
Dr.
Dr.
Henry Ho
Rafael Albanese
Michael LevGur
Mona Shangold
Adrienne Fleckman
Nalini Sastry
Eric Buffong
Sam Kogan (Visiting Fellow from Mexico)
Larry Grunfeld
Shoshanna Haberman
Anna Freitag
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Ruth Freeman, M.D.
Research Students
1998
1999
2000
2001
2002
2003
2005
2006
2007
2008
2010
Emily Stein
Alyssa Frenkel and Maria Emerson
Elana Fishman, Agnes Miller, Faith Horton & Emily Stein
Elyse H. Scheuer. Jennifer Berliner & Pal Lakaj
Patricia Eshaghian, Malka Skibo, Jennifer Neufeld & Carolyn Tadros
Hsuan Wei
Jennifer Gardner and Elizabeth Bendle (England)
Sara Rosenbaum
Ella Rosenbaum and Rena Pollack
Priya Kodiyanplakkal
Renee Rolston, Nicholas Teigan, Priya Kodiyanplakkal,
Oluwakemi Adegoke
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Ruth Freeman, M.D.