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LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
M.Sc. DEGREE EXAMINATION - BIOMED.INSTRUMENTATION SC.
FOURTH SEMESTER – APRIL 2011
BI 4953 - IMMUNOTECHNOLOGY
Date : 11-04-2011
Time : 1:00 - 4:00
Dept. No.
Max. : 100 Marks
Section- A
Answer all.
2X10= 20
1. Which components of the human body act as primary barriers?
2. List the contributions of Robert Koch and Burnet.
3. Illustrate the gene cluster for Antibody diversity.
4. Name any two compliment deficiency diseases.
5. List the participatory cells in type II hypersensitivity reactions.
6. Define DNA vaccines.
7. Expand the acronynm ELISA and any two applications.
8. What are the characteristics of an antigen?
9. Enlist the components involved in inflammation reaction.
10. What is the role of PBS in isolation of leucocytes?
Section- B
Answer any four of the following.
4x10=40
11. Write in detail about the organs involved in immune response.
12. Explain HLA cluster and its immunological importance.
13. Elaborate the extent of Autoimmune disorders with examples.
14. Is suppression of immune response possible? If Yes, why and how it is done?
15. Discuss any five immunodetection technique in detail
16. Describe the hypersensitivity reactions and also the tests to identify each category.
Section-C
Answer any two of the following.
2x20=40
17. Write in detail the chronological developments in the field of immunology.
18. Explain in detail immunoglobulin diversity.
19. Describe in detail the evasion mechanisms adopted by tumour cells and also add an account on
cancer immunotherapy.
20. Discuss, What are the various types of Antigen and antibody interactions.
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