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LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034 B.Sc. DEGREE EXAMINATION – ADVANCED ZOOLOGY AND BIOTECHNOLOGY FIFTH SEMESTER – NOVEMBER 2014 AZ 5517 - IMMUNOLOGY Date : 01/11/2014 Time : 09:00-12:00 Dept. No. Answer ALL the questions: Max. : 100 Marks PART-A (10x2=20) 1. What is innate immunity? 2. Write a note on Peyer’s patch. 3. Differentiate adjuvant from hapten. 4. Comment on antibody engineering. 5. What are cytokines? 6. What are autografts? 7. Define hypersensitivity. 8. What is immunotherapy? 9. Comment on yellow fever. 10. Write a note on graft rejection. PART – B Answer any FOUR questions: (4 x 10 = 40) 11. Give an account on different types of immunity. 12. Describe Thymus and bursa of Fabricius. 13. Briefly explain the characteristics of T and B cell epitopes. 14. Describe the structure and functions of antibodies. 15. Comment on regulation and modulation of immune response. 16. Discuss any four types of autoimmune diseases. 17. Write an account on immunity and Tumors. 18. Give a brief notes on prevention of post natal diseases. PART – C Answer any TWO questions: (2x20=40) 19. Write an essay on cells and organelles of immune system. 20. Give an account on transplantation immunology. 21. Explain monoclonal antibodies. 22. Write a detailed account on vaccines. $$$$$$$