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Global Biochip Markets: Microarrays and Lab-on-a-Chip
Description:
This report determines the status of current and emerging biochip technologies and products and assess
their worldwide growth potential over a five-year period from 2015 to 2020. The study is particularly focused
on characterizing the biochip markets by type (DNA microarray, protein microarray, emerging microarray,
lab-on-a-chip); by function (gene expression, genotyping, micro-RNA, epigenetic, sequence capture); and by
end user (R&D tools, drug discovery, and development, diagnostics, sequencing, applied).
The global market for biochip products reached nearly $3.9 billion in 2014. This market is projected to grow
from $4.7 billion in 2015 to $18.4 billion in 2020, representing a compound annual growth rate (CAGR) of
31.6% between 2015 and 2020.
This report provides:
- An overview of the global market for current and emerging biochip technologies.
- Analyses of global market trends, with data from 2014, 2015, and projections of CAGRs through 2020.
- Characterizations of biochip markets by type (DNA microarray, protein microarray, emerging microarray,
and lab-on-a-chip); by function (gene expression, genotyping, micro-RNA, epigenetic, sequence capture); and
by end-user (research-and-development tools, drug discovery and development, diagnostics, sequencing,
and applied).
- A focused study on the market for biochip-based diagnostics products, a major future segment for
biochips.
- Discussion of the main commercial biochip technologies and the commercial potential of the key market
segments.
- Examination of the factors that influence the market, including growth-driving forces, industry alliances and
acquisitions, applications in diagnostics and drug discovery, and customer needs.
- Patent analysis.
- Profiles of major players in the industry.
Scope And Format Of Report
The study scope includes the major biochip platforms, including DNA and protein microarrays, tissue/cell
and glycomics microarrays, LOAC products and NGS. Each platform is analyzed to determine its market
status, impact on future market segments, and forecast growth from 2015 through 2020. Technology status
and market driving forces are discussed, as well as influencing market factors like industry alliances and
acquisitions, applications in diagnostics and drug discovery, customer needs and competitive trends.
In addition to the main LOAC, microarray and sequencing industries, the report profiles several specialized
biochip industry segments including the following: DNA analyzers, ion channel screening, digital PCR, labelfree detection, nanoarray, peptide microarray, antibody microarray, antibody reagents, multiplex protein
diagnostics, circulating tumor cell, prenatal screening, point of care CD4 counting and China’s biochips
industries.
Applications for biochips-based diagnostics are highlighted in this report - particularly cancer diagnostics - as
well as new data about biochip substrate types.
This report also analyzes patent data for each biochip type. The industry has grown significantly since the
last report, and nearly 300 companies are profiled in our analysis.
Contents:
1: Introduction
- Study Goals And Objectives
- Reasons For Doing The Study
- Contribution Of The Study And Intended Audience
- Scope And Format Of Report
- Methodology
- Information Sources
- Disclaimer
2: Summary
- Table Summary : Global Market For Biochip Products By End Use, Through 2020
- Figure Summary : Global Market Trends For Biochip Products By End Use, 2014-2020
3: Overview
- Introduction
- Biochip Types
- Market Potential Of Biochips
- Driving Forces For Growth In Biochips Markets
- The Biochip Industry
4: Microarray Technologies
- Introduction
- DNA Microarray Technologies
- Protein Microarray Technologies
- Emerging Microarray Technologies
5: Lab-On-A-Chip Technologies
- Introduction
- Substrate Materials
- LOAC Types
- LOAC Applications
- Organ On Chip
- LOAC Technology Challenges
6: Drug Discovery And Development Applications
- Introduction
- Drug Industry Challenges
- Drug Discovery And Development Process
- Needs In The Drug Discovery And Development Process
7: Diagnostics Applications
- Introduction
- How Diagnostics Differ From Research Tools
- How Biological Content Drives The Growth Of Diagnostics
- Factors In Clinical Acceptance Of Biomarker-Based Tests
- Molecular Diagnostics
- Diagnostics Market Segments
- Test Sensitivity And Specificity
- Regulatory Status
- Biochips Cancer Applications
- Warfarin Sensitivity
- Infectious Diseases
- Neurological
- Cardiac Disorders
- Cystic Fibrosis
- Noninvasive Prenatal Screening
- Immune Disorders
8: Biochips Industry
- Biochips Industry Acquisitions, 2012 To 2015
- Biochips Industry Strategic Alliances
- LOAC Industry
- Next-Generation Sequencing Instrument Industry
- Microarray Industry
- Biochips Diagnostics Industry
- Agricultural Industry
- China's Biochip Industry
9: Biochips Markets
- Driving Forces For Biochips Growth
- Global Biochips Market
- DNA Microarray Markets
- Protein Microarrays Markets
- Emerging Microarrays Markets
- LOAC Markets
- NGS Markets
- Biochips Diagnostics Markets
- Biochips Markets By Region
10: Biochips Patents
- Microarray Patents
- LOAC Patents
- Clinical Next-Generation Sequencing Patents
11: Company Profiles
- 3Qbd
- 20/20 Gene Systems Inc.
- Abaxis Inc.
- Abbott Laboratories
- Abionic Sa
- Abtech Scientific Inc.
- Abacus Diagnostica Ltd.
- Accelerate Diagnostics Inc.
- Acea Biosciences Inc.
- Achira Labs Pvt. Ltd.
- Advanced Liquid Logic
- Affymetrix Inc.
- Agendia Bv
- Agenix Ltd.
- Agilent Technologies Inc.
- Akonni Biosystems
- Alere Technologies Gmbh
- Allegro Diagnostics Corp.
- Almac Group, Ltd.
- Analytik Jena Ag
- Aquamarijin Micro Filtration Bv
- Aquila Diagnostic Systems Inc.
- Arrayit Corporation
- Assurerx Health Inc.
- Atonomics A/S
- Aushon Biosystems Inc.
- Autogenomics Inc.
- Avacta Group Plc
- Aviana Molecular Technologies
- Axela Inc.
- Ayoxxa Biosystems Gmgh
- Beckman Coulter Inc.
- Becton, Dickinson And Co.
- Biocartis Nv
- Biocept Inc.
- Biodot Inc.
- Biofire Diagnostics Inc.
- Biofluidix Gmbh
- Bioforce Nanosciences Inc.
- Biomerieux Sa
- Bionanogenomics Inc.
- Biorad Laboratories Inc.
- Bioscale Inc.
- Biosurfit Sa
- Biosystems International
- Biotray
- Blue4Green
- Boditech Med Inc.
- Boehringer Ingelheim Microparts Gmbh
- Boston Microfluidics
- Cambridge Biomagnetics Ltd.
- Cancer Genetics Inc.
- Capitalbio Corporation
- Caris Life Sciences
- CBC Comprehensive Biomarker Center Gmbh
- Cellanyx Diagnostics Inc.
- Cellasic
- Cellectricon Ab
- Cellix, Ltd.
- Cellscape Corporation
- Cellular Research Inc.
- Celula Inc.
- Cepheid
- Clearbridge Biomedics
- Combimatrix Molecular Diagnostics Inc.
- Courtagen Life Sciences Inc.
- Creative Microsystems Corporation
- Customarray Inc.
- Cybrdi Inc.
- Cyclofluidic Ltd.
- Cynvenio Biosystems Inc.
- Cytocentrics Bioscience
- Cytoo Sa
- Debiotech S.A.
- Deltadot Ltd.
- Deos Labs
- Diagenic Asa
- Diagnostics For All
- Diagnoswiss S.A.
- Diaxonhit
- DNA Electronics Ltd.
- DNA Link Inc.
- DNAmicroarray Inc.
- Dolomite Microfluidics Ltd.
- Dr. Chip Biotech Inc.
- DST Diagnostische Systeme & Technologien Gmbh
- Dyconex Ag
- Eksigent
- Elveflow
- Elim Biopharmaceuticals Inc.
- Emulate Inc.
- Epigem Ltd.
- Epocal Inc.
- Euroimmun Ag
- Falcon Genomics Inc.
- Fluidigm Corporation
- Fluidware Technologies Inc.
- Fluimedix Aps
- Fluxion Biosciences Inc.
- Full Moon Biosystems Inc.
- Gen9 Inc.
- Genalyte
- Genefluidics, Inc.
- Genenews
- Genepoc Inc.
- Genmark Diagnostics, Inc.
- Genomedx Biosciences Inc.
- Genomica Sau
- Gigagen Inc.
- Gnubio Inc.
- Good Start Genetics Inc.
- Grace Bio Labs
- Gradientech Ab
- GWC Technologies Inc.
- Gyros Ab
- Hnu-Nanopoint
- Hologic Inc.
- Illumina, Inc.
- Immunovia Ab
- Inanovate Inc.
- Indx Lifecare
- Innosieve Diagnostics Bv
- Institute Of Microchemical Technology Co. Ltd.
- Intavis Bioanalytical Instruments Ag
- Intel Corporation
- Iquum Inc.
- Iris Biotechnologies Inc.
- Isu Abxis Co. Ltd.
- Johnson & Johnson
- Jpt Peptide Technologies Gmbh
- Kinexus Bioinformatics Corporation
- Lab21 Ltd.
- Laboratory Corporation Of America Inc.
- LC Sciences
- Leukodx Ltd.
- Life Technologies Inc.
- Lineagen Inc.
- Lionix Bv
- Luminex
- Magarray, Inc.
- Maxwell Sensors Inc.
- Medimate Bv
- Merck Kgaa
- Metamark Genetics Inc.
- Micro2Gen Ltd.
- Microchips Inc.
- Microdish Bv
- Microdrop Technologies Gmbh
- Microfab Technologies Inc.
- Microflexis Gmbh
- Microfluidic Chipshop Gmbh
- Microfluidic Innovations Llc
- Microfluidix Inc.
- Microliquid
- Microlytic
- Micronics Microfluidics
- Micronit Microfluidics Bv
- Micropoint Biosciences Inc.
- Micrux Technologies Sa
- Mingyuan Medicare Development Company Ltd.
- Mobidiag Oy/Ltd.
- Mode Dx Ltd.
- Molecular Cytomics Inc.
- Mycroarray Inc.
- Mycrolab Diagnostics Pty Ltd.
- Nanion Technologies Gmbh
- Nano Terra Inc.
- Nanobiosym
- Nanobiosys
- Nanocellect Biomedical Inc.
- Nanoentek Inc.
- Nanoivd Inc.
- Nanomi Bv
- Nanomix Inc.
- Nanospeed Diagnostics Inc.
- Nanosphere Inc.
- Nanostring Technologies Inc.
- NEC Corporation
- Neogen Corporation
- Neogenomics Laboratories
- Netbio Inc.
- Nexus Dx Inc.
- Novartis
- Nuclea Biotechnologies Inc.
- Opko Health Inc.
- Optotrack Inc.
- Osmotex Ag
- Ostendum R&D Bv
- Oxford Gene Technology
- Pamgene International Bv
- Pathgen Dx Pte Ltd.
- Pathogenetix Inc.
- Pathogenica
- Pepperprint Gmbh
- Pepscan Presto Bv
- Perkinelmer
- Phalanx Biotech Group
- Philips Electronics Nv
- Plexera Llc
- Positive Id Corporation
- Protagen Ag
- Protein Biotechnologies Inc.
- Proteus Digital Health Inc.
- Protneteomix Sas
- Qiagen
- Q-Linea Ab
- Quanterix Corporation
- Quantiscientifics Llc
- Quantum Dx
- Quest Diagnostics
- Qwane Biosciences S.A
- Raindance Technologies Inc.
- Randox Laboratories Ltd.
- Raybiotech Inc.
- Retrogenix Ltd.
- Rheonix
- Rheosense Inc.
- Ridge Diagnostics Inc.
- Roche Holding Ag
- Rosetta Genomics Inc.
- Samsung Electronics Co. Ltd.
- Sandstone Diagnostics Inc.
- Savyon Diagnostics Ltd.
- Scienion Ag
- Seegene Inc.
- Sengenics International Pte Ltd
- Sensimed Ag
- Senslab Gmbh
- Senzair B.V.
- SFC Fluidics Llc
- Shanghai Biochip Co. Ltd.
- Shanghai Huaguan Biochip Co. Ltd.
- Sharp Corporation
- Siamab Therapeutics Inc.
- Signal Genetics Llc
- Signature Diagnostics Ag
- Silicon Biosystems
- Siloam Biosciences Inc.
- Skylinedx
- Slipchip Llc
- Somalogic Inc.
- Sophion Bioscience (Biolin Scientific)
- Spartan Biosciences Inc.
- Sphere Fluidics Limited
- Sphere Medical Ltd.
- Spinchip Diagnostics As
- Spinomix
- SQI Diagnostics, Inc.
- Surmodics Inc.
- Surnetics
- Sysmex Inostics
- T2 Biosystems
- Tearlab Corporation
- Tecan Group Ltd.
- Thermo Fisher Scientific Inc.
- Thinxxs Microtechnology Ag
- Tianjin Biochip Corporation
- Tirf Labs Inc.
- Transgenomic Inc.
- Translume Inc.
- Trinean Nv
- Trinity Biotech Plc
- Trovagene Inc.
- US Biomax Inc.
- Veracyte Inc.
- Veredus Laboratories Pte Ltd.
- Wafergen Biosystems Inc.
- Wasatch Microfluidics
- Wave 80 Biosciences
- Wuxi Buosheng Bio-Engineering Co. Ltd.
- Xagenic Inc.
- Xona Microfluidics Llc
- YMC Co. Ltd.
- Zellkraftwerk Gmbh
- Zyomyx, Inc.
- Zyoxel Ltd.
List Of Tables
Summary Table : Global Market For Biochip Products By End Use, Through 2020
Table A : Scope Of Report
Table 1 : Biology Downsizing Revolution
Table 2 : Comparison Of Two Major Biochip Types
Table 3 : Biochip Nomenclature
Table 4 : Global Market For Biochip Products By Biochip Type, Through 2020
Table 5 : Driving Forces For Biochips Key Market Growth
Table 6 : Comparison Of Biochips Industries
Table 7 : The Nanoscale World
Table 8 : Types Of Microarray
Table 9 : Comparison Of DNA And Protein Microarray Technologies
Table 10 : Microarray Genome Content
Table 11 : DNA Microarray Platform Features
Table 12 : Applications Of DNA Microarray
Table 13 : Comparison Of Genetic Analysis Technologies
Table 14 : SNP Measurement Platforms
Table 15 : Comparison Of Chromosomal Change Detection Technologies
Table 16 : Workflow For A Micro-Rna Experiment
Table 17 : Comparison Of Bead-Based Arrays And Planar Microarrays
Table 18 : Protein Microarray Platforms
Table 19 : Protein Microarrays As Research Tools
Table 20 : Product Types Of Protein Microarray
Table 21 : Technical Challenges Of Protein Microarray
Table 22 : Emerging Microarray Technologies
Table 23 : LOAC Product Life Cycle Stage
Table 24 : Biochips Substrate Materials
Table 25 : Types Of LOAC
Table 26 : Workflow Comparison Of Selected Next-Generation DNA Sequencing Platforms
Table 27 : Biochip Content In Next-Generation Sequencing Machines
Table 28 : Segments Of LOAC Market
Table 29 : Microfluidic Systems Advantages For Biochemical Analysis
Table 30 : Technical Challenges Of LOAC Technology
Table 31 : Biochip Key Life Sciences Market Segments
Table 32 : Biochip Applications In Drug Discovery And Development
Table 33 : Key Needs In Drug Discovery And Development
Table 34 : Diagnostics Paradigm Shift
Table 35 : Requirements For An Epigenetics Bisulfite Diagnostic Assay
Table 36 : Biomarkers Used In Biochip-Based Diagnostics
Table 37 : Rate Of Adoption Of DNA Microarray Diagnostics Tests
Table 38 : Comparison Of DNA-Based MDX Platforms
Table 39 : Factors Affecting Penetration Of Next-Generation Formats Into The MDX Market
Table 40 : U.S. Incidence For Selected Cancers, 2012
Table 41 : Status Of Advanced Bladder Cancer Diagnostics
Table 42 : Estimated Number Of Annual Breast Cancer Treatment Decisions In The U.S. By Cancer
Classification
Table 43 : Breast Cancer MDX Technology Platforms
Table 44 : Status Of Advanced Breast Cancer Diagnostics
Table 45 : Status Of Advanced HPV Diagnostics
Table 46 : Current Screening And Diagnostics Tests For Colorectal Cancer
Table 47 : Status Of Advanced Colorectal Cancer Diagnostics
Table 48 : MDX Technology Platforms For Detecting Cup
Table 49 : Status Of Advanced Kidney Cancer Diagnostics
Table 50 : Status Of Advanced Leukemia Diagnostics
Table 51 : Status Of Liver Cancer Next-Generation Dx Tests
Table 52 : Status Of Advanced Lymphoma Cancer Diagnostics
Table 53 : Five-Year Survival Rates For Non-Small Cell Lung Cancer
Table 54 : Status Of Advanced Lung Cancer Diagnostics
Table 55 : Status Of Advanced Melanoma Diagnostics
Table 56 : Early Screening Tests For Ovarian Cancer
Table 57 : Status Of Ovarian Cancer Next-Generation Diagnostics Tests
Table 58 : Status Of Advanced Pancreatic Cancer Diagnostics
Table 59 : Status Of Advanced Prostate Cancer Diagnostics
Table 60 : Status Of Advanced Thyroid Cancer Diagnostics
Table 61 : Next-Generation Dx Test Summary By Indication And Technology
Table 62 : Importance Of CYP Genes In Drug Metabolism
Table 63 : Status Of Advanced Warfarin CYP Pharmacogenetic Diagnostics
Table 64 : Status Of MRSA And C. Difficile Advanced Diagnostics
Table 65 : Status Of Influenza Advanced Diagnostics
Table 66 : Status Of CT/NG Advanced Diagnostics
Table 67 : Diagnostics Approaches For Alzheimer's Disease
Table 68 : Status Of Alzheimer's Disease Advanced Diagnostics Tests
Table 69 : BNP Molecular Diagnostics Tests For Congestive Heart Failure
Table 70 : Advanced Diagnostics Tests For Cystic Fibrosis
Table 71 : Next-Generation Sequencing-Based Prenatal Diagnostics Industry
Table 72 : HLA Testing Market
Table 73 : Acquisitions In The Biochips Industry, 2012-2015
Table 74 : Microarray Industry Strategic Alliances, 2012-2013
Table 75 : LOAC/NGS Industry Strategic Alliances, 2012-2013
Table 76 : LOAC Competitor Landscape
Table 77 : Leading LOAC Instrument Manufacturers
Table 78 : Forensic Applications For LOAC-Based DNA Analyzers
Table 79 : LOAC Diagnostics Industry
Table 80 : Ion Channel Screening Industry
Table 81 : Digital Pcr Industry
Table 82 : LOAC University Spin-Offs
Table 83 : Key LOAC Acquisitions By Leading Life Science Companies
Table 84 : Next-Generation Sequencing Instrument Companies: Commercial Phase
Table 85 : Suspension Bead/Gel-Based Microarray Industry
Table 86 : Label-Free Detection Industry
Table 87 : Nanoarray Industry
Table 88 : Key Peptide Microarray Companies
Table 89 : Key Antibody Microarray Companies
Table 90 : Estimated Market Share For Key Antibody Reagents Companies, 2012
Table 91 : Multiplex Protein In Vitro Diagnostics Companies
Table 92 : CTC Biochips Industry
Table 93 : North American Test Costs And Prices, 2014
Table 94 : Next-Generation Sequencing-Based, Noninvasive Prenatal Diagnostic Market Share By Test
Revenue, 2014
Table 95 : Noninvasive Prenatal Diagnostics Potential Future Competitors
Table 96 : POC CD4 Industry
Table 97 : Biochips-Based Companies In Agricultural Industry
Table 98 : China Biochip Industry
Table 99 : Key Market Growth Driving Forces For Biochips
Table 100 : Global Market For Biochip Products By Type, Through 2020
Table 101 : Global Market For Biochips By End-Use Industry, Through 2020
Table 102 : Properties Of Biochips Substrate Materials
Table 103 : Global Market For Biochips By Substrate Material, Through 2020
Table 104 : Global Market For DNA Microarrays By End Use, Through 2020
Table 105 : Global Contribution Of DNA Microarrays By Analysis Type, 2015
Table 106 : Global Market For DNA Microarrays By Substrate Material, Through 2020
Table 107 : Competitive Platforms By Multiplexing Density
Table 108 : Global Market For Protein Microarrays By End Use, Through 2020
Table 109 : Global Market For Proteomic Microarrays By Substrate Material, Through 2020
Table 110 : Competitors Of Coated Microarray Slide Market Principal
Table 111 : Global Contribution Of Proteomic Arrays By Array Type, 2015
Table 112 : Global Contribution Of Emerging Arrays By Array Type, 2015
Table 113 : Global Market For Emerging Arrays By End Use, Through 2020
Table 114 : Global Market For Emerging Arrays By Substrate Material, Through 2020
Table 115 : Global Market For Genomics Lab-On-A-Chip By End-User Industry, Through 2020
Table 116 : Global Market For Genomics LOAC By Substrate Material, Through 2020
Table 117 : Global Market For Proteomic LOAC By End-User Industry, Through 2020
Table 118 : Global Market For Proteomics LOAC By Substrate Material, Through 2020
Table 119 : Global Market For The NGS Market By End-User Industry, Through 2020
Table 120 : Global Market For NGS By Substrate Material, Through 2020
Table 121 : Global Contribution Of NGS By Test Complexity, 2015
Table 122 : Global Market For Diagnostics Assays By Biochip Type, Through 2020
Table 123 : Adoption Rate For DNA Microarrays In Diagnostics
Table 124 : Global Contribution Of Diagnostics Market By Indication, 2015
Table 125 : Global Contribution Of Diagnostics Market By Substrate Material, 2015
Table 126 : Global Contribution Of Cancer Diagnostics Market By Biochip Type, 2015
Table 127 : Global Contribution Of Cancer Diagnostics Market By Indication, 2015
Table 128 : Status Of Proteomics-Based Diagnostics For Cancer Applications, 2015
Table 129 : Global Market For Biochips By Region, Through 2020
Table 130 : Global Market For Microarray Market By Region, Through 2020
Table 131 : Global Market For LOAC By Region, Through 2020
Table 132 : Global Market For NGS By Region, Through 2020
Table 133 : DNA Microarray Patents By Region, 2002-2012
Table 134 : Microarray-Related Proteomics Patents By Region, 2002-2012
Table 135 : Microarray-Related Patents By Application And Title,2013-2015
Table 136 : LOAC-Related Proteomics Patents By Region, 2002-2012
Table 137 : LOAC-Related Patents By Application And Title, 2013-2015
Table 138 : Clinical Next-Generation Sequencing Patents, 2002-2012
Table 139 : Clinical NGS-Related Patents By Application And Title, 2013-2015
Table 140 : Clinical Next-Generation Sequencing Patents By Indication, 2002-2012
Table 141 : Agendia Microarray-Based Diagnostics Pipeline
Table 142 : Akonni Biochip Grants
Table 143 : Rosetta's Diagnostics Tests
Table 144 : Seegene Biochips Collaborations
List Of Figures
Summary Figure : Global Market Trends For Biochip Products By End Use, 2014-2020
Figure 1 : Microarray Feature Density
Figure 2 : Microarray Resolution
Figure 3 : Relative Number Of Disease-Causing Alleles At Maf5 And Maf1
Figure 4 : Upstream And Downstream Steps In Epigenetic Analysis`
Figure 5 : Importance Of Proteins
Figure 6 : Protein Analysis Approaches Contrasted
Figure 7 : Drug Discovery And Development Timescale
Figure 8 : Validation Gap For Future Drug Targets
Figure 9 : Sensitivity And Specificity
Figure 10 : Entries To Mirna Database, 2002-2014
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