Download Carlos IBANEZ

Name: Carlos Ibanez
Designation: Professsor
Office Address: 28 Medical Drive,
Centre for Life Sciences, NUS
Singapore 117456
Contact details: +65 6516 5889
MAJOR RESEARCH INTERESTS
1. Cell and Molecular Biology
2. Neurobiology
3. Molecular Endocrinology
4. Molecular Medicine
SELECTED PUBLICATIONS
1. Funakoshi, H., Belluardo, N., Arenas, E., Yamamoto, Y., Casabona, A., Persson, H. and
Ibáñez, C.F. (1995) Muscle-derived neurotrophin-4 as an activity-dependent trophic signal for
adult motor neurons. Science, 268: 1495-1499.
2. Trupp, M., Arenas, E., Fainzilber, M., Nilsson, A.-S., Sieber, B.A., Grigoriou, M., Kilkenny,
C., Salazar-Grueso, E., Pachnis, V., Arumäe, U., Sariola, H., Saarma, M. and Ibáñez, C.F.
(1996) Functional receptor for glial cell line-derived neurotrophic factor encoded by the c-ret
proto-oncogene product. Nature, 381, 785-789.
3. Ringstedt, T., Linnarsson, S., Lendahl, U., Kokaia, Z.,Arenas, E., Ernfors, P. and Ibáñez, C.F.
(1998) BDNF regulates reelin expression and Cajal-Retzius cell development in the cerebral
cortex. Neuron, 21, 305-315.
4. Ledda, F., Paratcha, G. and Ibáñez, C. F. (2002). Target-derived GFRa1 as an attractive
guidance signal for developing sensory and sympathetic axons via activation of Cdk5. Neuron,
36, 387-401.
5. Paratcha, G., Ledda, F. and Ibáñez, C.F. (2003) The neural cell adhesion molecule NCAM is
an aternative signaling receptor for GDNF family ligands. Cell, 113, 867-879.
6. Pozas, E. and Ibáñez, C.F. (2005) GDNF and GFR 1 promote differentiation and tangential
migration of cortical GABAergic neurons. Neuron, 45, 701-713.
7. Ledda, F., Paratcha, G., Sandoval-Guzmán, T. and Ibáñez, C.F. (2007) GDNF and GFRa1
promote formation of neuronal synapses by ligand-induced cell adhesion. Nat. Neurosci., 10,
293-300.
8. Bertolino, P., Nilsson, R., Reissmann, E., Andersson, O., Berggren, P.-O. and Ibáñez, C.F.
(2008) Activin B receptor ALK7 is a negative regulator of pancreatic -cell function. Proc.
Natl. Acad. USA, 105, 7246-7251.
9. Vilar, M., Charalampopoulos, I., Kenchappa, R.S., Simi, A., Karaca, E., Reversi, A., Choi, S.,
Bothwell, M., Mingarro, I., Friedman, W.J., Schiavo, G., Bastiaens, P.I.H., Verveer, P.J.,
Carter, B.D. and Ibáñez, C.F. (2009) Activation of the p75 neurotrophin receptor through
conformational rearrangement of disulphide-linked receptor dimers. Neuron, 62, 72-83.
10. Charalampopoulos, I., Vicario, A., Pediaditakis, I., Gravanis, A., Simi, A. and Ibáñez, C.F.
(2012) Genetic dissection of neurotrophin signaling through the p75 neurotrophin receptor. Cell
Reports, 2, 1563-1570.