Survey
* Your assessment is very important for improving the work of artificial intelligence, which forms the content of this project
* Your assessment is very important for improving the work of artificial intelligence, which forms the content of this project
Curriculum Vitae Myron Yaster, M.D. CURRICULUM VITAE The Johns Hopkins University Of Medicine ________________________________ Myron Yaster, M.D. June 1, 2012 Current Appointments 2011- Professor of Neurosurgery The Johns Hopkins Hospital The Johns Hopkins University, School of Medicine Baltimore, Maryland 2003 - Richard J. Traystman Distinguished Professor of Pediatric Anesthesia, Critical Care Medicine, and Pain Management The Johns Hopkins Hospital The Johns Hopkins University, School of Medicine Baltimore, Maryland 2000 - Professor of Anesthesiology and Critical Care Medicine The Johns Hopkins Hospital The Johns Hopkins University, School of Medicine Baltimore, Maryland 2000 - Professor of Pediatrics The Johns Hopkins Hospital The Johns Hopkins University, School of Medicine Baltimore, Maryland Personal Data Office: Department of Anesthesiology and Critical Care Medicine The Johns Hopkins Hospital The Charlotte R. Bloomberg Children’s Center 1800 Orleans Street, Suite 6320 Baltimore, Maryland 2l287 Telephone: Fax: E-Mail address: Website: (410) 614-6223, 410-955-7610 (410) 614-7509 [email protected] www.meddium.com/myronyaster 1 Curriculum Vitae Myron Yaster, M.D. 2 Education And Training l970-l974 B.S., Brooklyn College of the City University of New York l973-l977 M.D., State University of New York - Downstate Medical Center, New York l977-l978 Intern in Pediatrics, Children's Hospital of Pittsburgh, Pittsburgh, PA l978-l979 Resident in Pediatrics, Children's Hospital of Pittsburgh, Pittsburgh, PA l979-l98l Resident in Anesthesia, The Hospital of the University of Pennsylvania, Philadelphia, PA l98l-l982 Fellowship, Pediatric Anesthesia and Critical Care Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA Professional Experience 1997 - 2003 Clinical Director, Division of Pediatric Anesthesiology, Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins Hospital The Johns Hopkins University, School of Medicine Baltimore, Maryland 1989 - 2005 Director, Multi-Disciplinary Pain Service, the Children's Medical and Surgical Center, The Johns Hopkins Hospital 1990 - 2000 Associate Professor of Anesthesiology and Critical Care Medicine The Johns Hopkins Hospital The Johns Hopkins University, School of Medicine Baltimore, Maryland 1990 - 2000 Associate Professor of Pediatrics The Johns Hopkins Hospital The Johns Hopkins University, School of Medicine Baltimore, Maryland 1989 - 1992 Co-Director, Intermediate Care Unit, the Children's Medical and Surgical Center, The Johns Hopkins Hospital 1983 -1990 Assistant Professor of Anesthesiology and Critical Care Medicine The Johns Hopkins Hospital The Johns Hopkins University, School of Medicine Curriculum Vitae Myron Yaster, M.D. 3 Baltimore, Maryland 1982 - 1983 Instructor, Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins Hospital The Johns Hopkins University, School of Medicine Baltimore, Maryland 198l - l982 Administrative Fellow, Department of Anesthesiology, The Children's Hospital of Philadelphia, Philadelphia, PA RESEARCH ACTIVITIES Original Publications 1. Azizkhan RG, Dudgeon DL, Buck JR, Colombani PM, Yaster M, Nichols D, Civin C, Kramer SS, Haller JA, Jr: Life-threatening airway obstruction as a complication to the management of mediastinal masses in children. J Pediatr Surg 1985; 20:816-22. 2. Yaster M, Simmons RS, Tolo VT, Pepple JM, Wetzel RC, Rogers MC: A comparison of nitroglycerin and nitroprusside for inducing hypotension in children: A double-blind study. Anesthesiology 1986; 65:175-9. 3. Wetzel RC, Marsh BR, Yaster M, Casella JF: Anesthetic implications of protein C deficiency. Anesth Analg 1986; 65:982-4. 4. Yaster M, Koehler RC, Traystman RJ: Effects of fentanyl on cerebral and peripheral hemodynamics in neonatal lambs. Anesthesiology 1987; 66:524-30. 5. Yaster M: The dose response of fentanyl in neonatal anesthesia. Anesthesiology 1987; 66:433-5. 6. Maxwell LG, Yaster M, Wetzel RC, Niebyl JR: The safety and efficacy of penile nerve block for newborn circumcision. Obstet Gynecol 1987; 70:415-9. 7. Yaster M, Buck JR, Dudgeon DL, Manolio TA, Simmons RS, Zeller P, Haller JA: Hemodynamic effects of primary closure of omphalocele/gastroschisis in newborns. Anesthesiology 1988; 69:84-8. 8. Yaster M, Koehler RC, Traystman RJ: Interaction of fentanyl and pentobarbital on cerebral and peripheral hemodynamics in newborn lambs. Anesthesiology 1989; 70:461-9. 9. Yaster M, Scherer LR, Stone M, Maxwell LG, Schleien CL, Wetzel RC, Buck JR, Nichols DG, Colombani PM, Dudgeon DL, Haller JA: Determination of safe primary closure of congenital abdominal wall defects using intraoperative predictors. J Pediatr Surg 1989; 42:1217-20. 10. Yaster M, Nichols DG, Deshpande JK, Wetzel RC: Midazolam-fentanyl intravenous sedation in children. Case report of respiratory arrest. Pediatrics 1990; 86:463-7. 11. Spear RM, Yaster M, Berkowitz ID, Maxwell LG, Bender KS, Naclerio R, Manolio TA, Nichols DG: Preinduction of anesthesia in children with rectally administered midazolam. Anesthesiology 1991; 71:670-4. Curriculum Vitae Myron Yaster, M.D. 4 12. Nichols DG, Yaster M, Lynn AM, Helfaer MA, Deshpande JK, Manson PN, Carson BS, Bezman M, Maxwell LG, Tobias JD, Grochow LB: Disposition and respiratory effects of intrathecal morphine in children. Anesthesiology 1993; 79:733-8. 13. Yaster M, Tobin JR, Billett C, Casella JF, Dover G: Epidural analgesia in the management of vaso-occlusive sickle cell crisis. Pediatrics 1994; 93:310-5. 14. Maxwell LG, Martin LD, Yaster M: Bupivacaine-induced cardiac toxicity in neonates-successful treatment with intravenous phenytoin. Anesthesiology 1994; 80:682-6. 15. Yaster M, Sola JE, Pegoli WP, Paidas CN: The night after surgery: Postoperative management of the pediatric outpatient-surgical and anesthetic aspects. Pediatr Clin North Am 1994; 41:199-220. 16. Yaster M, Koehler RC, Traystman RJ: Interaction of fentanyl and nitrous oxide on peripheral and cerebral hemodynamics in newborn lambs. Anesthesiology 1994; 80:364-71. 17. Lenox WC, Kost-Byerly S, Shipley R, Yaster M: Pediatric caudal epidural catheter sequestration: an unusual complication. Anesthesiology 1995; 83(5):1112-4. 18. Greenberg RS, Maxwell LG, Zahurak M, Yaster M: Preanesthetic medication of children with midazolam using the Biojector jet injector. Anesthesiology 1995; 83: 264-9. 19. Yaster, M., Kost-Byerly, S., Berde, C., and Billet, C. The management of opioid and benzodiazepine dependence in infants, children, and adolescents. Pediatrics 1996; 98(1):135-40. 20. Wong, D.F., Harris, J.C., Naidu, S., Yokoi, F., Marenco, S., Dannals, R.F., Ravert, H.T., Yaster, M., Evans, A., Rousset, O., Bryan, R.N., Gjedde, A., Kuhar, M.J., and Breese, G.R. Dopamine transporters are markedly reduced in Lesch-Nyhan disease in vivo. Proc Natl Acad Sci U S A 1996; 93(11):5539-43. 21. Fisher QA, Shaffner DH, Yaster M: Detection of intravascular injection of regional anaesthetics in children. Can J Anaesth 1997; 44(6):592-8. 22. Harris JC, Lee RR, Jinnah HA, Wong DF, Yaster M, Bryan RN: Craniocerebral magnetic resonance imaging measurement and findings in Lesch-Nyhan syndrome. Arch Neurol 1998; 55:547-53. 23. Kost-Byerly S, Tobin JR, Greenberg RS, Billett C, Zahurak M, Yaster M: Bacterial colonization and infection rate of continuous epidural catheters in children. Anesth Analg 1998; 86:712-6. 24. Rich JB, Yaster M, Brandt J: Anterograde and retrograde memory in children anesthetized with propofol. J Clin Exp Neuropsychol 1999; 21:535-46. 25. Greenberg RS, Billett C, Zahurak M, Yaster M: Videotape increases parental knowledge about pediatric pain management. Anesth Analg 1999; 89:899-903. 26. Monitto CL, Greenberg RS, Kost-Byerly S, Wetzel RC, Yaster M: The safety and efficacy of parent-/nurse-controlled analgesia in patients less than six years of age. Anesth Analg 2000; 91 (3):573-9. 27. Aram, L, Krane EJ, Kozlowski LJ, Yaster M: Tunneled epidural catheters for prolonged analgesia in pediatric patients. Anesth Analg 2001; 92(6):1432-8. Curriculum Vitae 28. Myron Yaster, M.D. 5 Davis PJ, Galinkin J, McGowan FX, Lynn AM, Yaster M, Rabb MF, Krane EJ, Kurth CD, Blum RH, Maxwell L, Orr R, Szmuk P, Hechtman D, Edwards S, Henson LG: A randomized multicenter study of remifentanil compared with halothane in neonates and infants undergoing pyloromyotomy. I. Emergence and recovery profiles. Anesth Analg 2001; 93: 1380-6. 29. Galinkin JL, Davis PJ, McGowan FX, Lynn AM, Rabb MF, Yaster M, Henson LG, Blum R, Hechtman D, Maxwell L, Szmuk P, Orr R, Krane EJ, Edwards S, Kurth CD: A Randomized Multicenter Study of Remifentanil Compared with Halothane in Neonates and Infants Undergoing Pyloromyotomy. II. Perioperative Breathing Patterns in Neonates and Infants with Pyloric Stenosis. Anesth Analg 2001; 93:1387-92. 30. Villemagne PM, Naidu S, Villemagne VL, Yaster M, Wagner HN, Jr., Harris JC, Moser HW, Johnston MV, Dannals RF, Wong DF: Brain glucose metabolism in Rett Syndrome. Pediatr.Neurol. 2002; 27:117-22. 31. Liaw WJ, Zhang B, Tao F, Yaster M, Johns RA, Tao YX: Knockdown of spinal cord postsynaptic density protein-95 prevents the development of morphine tolerance in rats. Neuroscience 2004; 123:11-5. 32. Tao F, Liaw WJ, Zhang B, Yaster M, Rothstein JD, Johns RA, Tao YX: Evidence of neuronal excitatory amino acid carrier 1 expression in rat dorsal root ganglion neurons and their central terminals. Neuroscience 2004; 123:1045-51. 33. Schwengel DA, McGready J, Berenholtz SM, Kozlowski LJ, Nichols DG, and Yaster M: Peripherally inserted central catheters: a randomized, controlled, prospective trial in pediatric surgical patients. Anesth Analg 2004;99:1038-43. 34. Maxwell LG, Kaufmann SC, Bitzer S, Jackson EV, Jr., McGready J, Kost-Byerly S, Kozlowski L, Rothman SK, Yaster M: The effects of a small-dose naloxone infusion on opioid-induced side effects and analgesia in children and adolescents treated with intravenous patient-controlled analgesia: a double-blind, prospective, randomized, controlled study. Anesth Analg 2005; 100: 953-8. 35. Gottschalk A, Berkow LC, Stevens RD, Mirski M, Thompson RE, White ED, Weingart JD, Long DM, Yaster M: Prospective evaluation of pain and analgesic use following major elective intracranial surgery. J Neurosurg 2007; 106:210-6. 36. Guan Y, Yaster M, Raja SN, Tao YX: Genetic knockout and pharmacologic inhibition of neuronal nitric oxide synthase attenuate nerve injury-induced mechanical hypersensitivity in mice. Mol Pain 2007; 3:29-34. 37. Maher EN, Hansen SF, Heine M, Meers H, Yaster M, Hunt EA: Knowledge of procedural sedation and analgesia of emergency medicine physicians. Pediatr Emerg Care 2007; 23:869-76. 38. Berde CB, Yaster M, Meretoja O, McCann ME, Huledal G, Gustafsson U, Larsson LE: Stable plasma concentrations of unbound ropivacaine during postoperative epidural infusion for 24-72 hours in children. Eur J Anaesthesiol 2008; 25(5):410-7. 39. Kost-Byerly S, Jackson EV, Yaster M, Kozlowski LJ, Mathews RI, Gearhart JP: Perioperative anesthetic and analgesic management of newborn bladder exstrophy repair. J Pediatr Urol 2008; 4:280-5. Curriculum Vitae 40. Myron Yaster, M.D. 6 Heitmiller ES, Nelson KL, Hunt EA, Schwartz JM, Yaster M, Shaffner DH: A survey of anesthesiologists' knowledge of American Heart Association Pediatric Advanced Life Support Resuscitation Guidelines. Resuscitation 2008; 79:499-505 41. Liaw WJ, Zhu XG, Yaster M, Johns RA, Gauda EB, Tao YX: Distinct expression of synaptic NR2A and NR2B in the central nervous system and impaired morphine tolerance and physical dependence in mice deficient in postsynaptic density-93 protein. Mol Pain 2008; 4:45. 42. Hammer GB, Verghese ST, Drover DR, Yaster M, Tobin JR: Pharmacokinetics and pharmacodynamics of fenoldopam mesylate for blood pressure control in pediatric patients. BMC Anesthesiol 2008; 8:6. 43. Park JS, Yaster M, Guan X, Xu JT, Shih MH, Guan Y, Raja SN, Tao YX: Role of spinal cord alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors in complete Freund's adjuvant-induced inflammatory pain. Mol Pain 2008; 4:67. 44. Lee BH, Lehmann CU, Jackson EV, Kost-Byerly S, Rothman S, Kozlowski L, Miller MR, Pronovost PJ, Yaster M: Assessing controlled substance prescribing errors in a pediatric teaching hospital: an analysis of the safety of analgesic prescription practice in the transition from the hospital to home. J Pain 2009; 10:160-6. 45. Singh OV, Yaster M, Xu JT, Guan Y, Guan X, Dharmarajan AM, Raja SN, Zeitlin PL, Tao YX. Proteome of synaptosome-associated proteins in spinal cord dorsal horn after peripheral nerve injury. Proteomics 2009; 9(5):1241-53. 46. Morad AH, Winters BD, Yaster M, Stevens RD, White ED, Thompson RE, Weingart JD, Gottschalk A. Efficacy of intravenous patient-controlled analgesia after supratentorial intracranial surgery: a prospective randomized controlled trial. J Neurosurg 2009; 111(2):343-50. 47. Agthe AG, Kim GR, Mathias KB, Hendrix CW, Chavez-Valdez R, Jansson L, Lewis TR, Yaster M, Gauda EB: Clonidine as an adjunct therapy to opioids for neonatal abstinence syndrome: a randomized, controlled trial. Pediatrics 2009; 123(5):e849-56. 48. Nelson KL, Yaster M, Kost-Byerly S, Monitto CL. A national survey of American Pediatric Anesthesiologists: patient-controlled analgesia and other intravenous opioid therapies in pediatric acute pain management. Anesth Analg 2010; 110(3):754-60. 49. Singh OV, Yaster M, Xu JT, GuanY, Guan X, Dharmarajan AM, Raja SN, Zeitlin PL, TaoYX. Proteome of synaptosome-associated proteins in spinal cord dorsal horn after peripheral nerve injury. Proteomics 2009; 9(5):1241-53. 50. Atianjoh FE, Yaster M, Zhao X, Takamiya K, Xia J, Gauda EB, Huganir RL, Tao YX. Spinal cord protein interacting with C kinase 1 is required for the maintenance of complete Freund's adjuvant-induced inflammatory pain but not for incision-induced post-operative pain. Pain 2010; 151(1):226-34. 51. Xu JT, Zhao X, Yaster M, Tao YX. Expression and distribution of mTOR, p70S6K, 4EBP1, and their phosphorylated counterparts in rat dorsal root ganglion and spinal cord dorsal horn. Brain Res 2010; 1336:46-57. 52. Wang W, Petralia RS, Takamiya K, Xia J, Li YQ, Huganir RL, Tao YX, Yaster M. Curriculum Vitae Myron Yaster, M.D. 7 Preserved acute pain and impaired neuropathic pain in mice lacking protein interacting with C Kinase 1. Mol Pain 2011; 7(1):11. 53. Yaster M, Guan X, Petralia RS, Rothstein JD, Lu W, Tao YX. Effect of Inhibition of Spinal Cord Glutamate Transporters on Inflammatory Pain Induced by Formalin and Complete Freund's Adjuvant. Anesthesiology 2011; 114(2):412-23. 54. Yang CP, Veltri MA, Anton B, Yaster M, Berkowitz ID. Food and Drug Administration approval for medications used in the pediatric intensive care unit: A continuing conundrum. Pediatr Crit Care Med 2011; 12(5):e195-9. 55. Firth PG, McMillan KN, Haberkern CM, Yaster M, Bender MA, Goodwin SR. A survey of perioperative management of sickle cell disease in North America. Paediatr Anaesth 2011; 21(1):43-9. 56. Hayes M, Yaster M, Haythornthwaite JA, Riekert K, Nelson K, White E, Mogayzel P, Lechtzin N. Pain is a common problem affecting clinical outcomes in adults with cystic fibrosis. Chest 2011; 140(6):1598-603. 57. Wang W, Atianjoh F, Gauda EB, Yaster M, Li Y, Tao YX. Increased expression of sodium channel subunit Nav1.1 in the injured dorsal root ganglion after peripheral nerve injury. Anat Rec (Hoboken) 2011; 294(8):1406-11. 58. Monitto CL, Kost-Byerly S, White E, Lee CK, Rudek MA, Thompson C, Yaster M. The optimal dose of prophylactic intravenous naloxone in ameliorating opioid-induced side effects in children receiving intravenous patient-controlled analgesia morphine for moderate to severe pain: A dose finding study. Anesth Analg 2011; 113(4):834-42. 59. Morad A, Winters B, Stevens R, White E, Weingart J, Yaster M, Gottschalk A. The efficacy of intravenous patient-controlled analgesia after intracranial surgery of the posterior fossa: A prospective, randomized controlled trial. Anesth Analg 2012; 114(2):416-23. 60. Berde CB, Walco GA, Krane EJ, Anand KJ, Aranda JV, Craig KD, Dampier CD, Finkel JC, Grabois M, Johnston C, Lantos J, Lebel A, Maxwell LG, McGrath P, Oberlander TF, Schanberg LE, Stevens B, Taddio A, von Baeyer CL, Yaster M, Zempsky WT. Pediatric analgesic clinical trial designs, measures, and extrapolation: report of an FDA scientific workshop. Pediatrics 2012; 129(2):354-64. 61. Shih MH, Kao SC, Wang W, Yaster M, Tao YX. Spinal cord NMDA receptor-mediated activation of mammalian target of rapamycin is required for the development and maintenance of bone cancer-induced pain hypersensitivities in rats. J Pain 2012; 13(4):338-49. 62. Kao SC, Zhao X, Lee CY, Atianjoh FE, Gauda EB, Yaster M, Tao YX. Absence of μ opioid receptor mRNA expression in astrocytes and microglia of rat spinal cord. Neuroreport 2012; 18;23(6):378-84. 63. Smith MC, Williamson J, Yaster M, Boyd GJ, Heitmiller ES. Off-label use of medications in children undergoing sedation and anesthesia. Anesth Analg 2012 Mar 26. [Epub ahead of print]. Curriculum Vitae Myron Yaster, M.D. 8 Review Articles in Peer-Reviewed Journals 1. Yaster M, Deshpande JK: Management of pediatric pain - use of opioid analgesics. J Pediatr 1988; 113:421-9. 2. Yaster M, Maxwell LG: Pediatric regional anesthesia - a review. Anesthesiology 1989; 70:324-38. 3. Yaster M, Deshpande JK, Maxwell LG: The pharmacologic management of pain in children. Compr Ther 1989; 15:14-26. 4. Yaster M, Maxwell LG, Nicholas E, Desphande JK: The management of acute pain in children with local anesthetics: A primer for the non-anesthesiologist. Compr Ther 1991; 17:27-35. 5. Yaster M, Nicholas EJ, Maxwell LG: The use of opioids in pediatric anesthesia and in the management of childhood pain. Anesthesiology Clinics of North America, 1991; 9:745-62. 6. Yaster M, Tobin JR, Fisher QA,Maxwell LG: Local anesthetics in the management of acute pain in children. J Pediatr 1994; 124: 165-76. 7. Yaster M, Kost-Byerly S, Greenberg RS, Maxwell LG: The management of acute pain in the traumatized child. International Anesthesia Clinics 1996; 409-35. 8. Yaster, M., Cohen, D., Monitto, C.L., Davis, P.J. The use of opioids in pediatric anesthesia and in the management of childhood pain. Am J Anesthesiol 1996; 23:182-9. 9. Galloway KS, Yaster M: Pain and symptom control in terminally ill children. Pediatr Clin North Am 2000; 47:711-46. 10. Golianu B, Krane EJ, Galloway KS, Yaster M: Pediatric acute pain management. Pediatr Clin North Am 2000; 47:559-87. 11. Yaster M, Kost-Byerly S, Maxwell LG: The management of pain in sickle cell disease. Pediatr Clin North Am 2000; 47:699-710. 12. Maxwell LG, Yaster M: Perioperative management issues in pediatric patients. Anesthesiol Clin North Am. 2000; 18(3):601-32. 13. Yaster M, Nichols DG: Pain management in the critically ill child. Indian J Pediatr 2001; 68:749-69. 14. Gottschalk A, Yaster M: Pain management after neruosurgery. Neurosurg Q 2007; 17:6473. 15. Gottschalk A, Yaster M: Pain management after caniotomy Part I. Contemporary Neurosurgery 2008; 30 (10):1-8. 16. Gottschalk A, Yaster M: Pain management after Craniotomy Part II. Contemporary Neurosurgery 2008; 30 (11):1-8. 17. Gottschalk A, Yaster M: The perioperative management of pain from intracranial surgery. Neurocrit Care 2009;10(3):387-402. 18. Galinkin JL, Demmer L, Yaster M: Genetics for the pediatric anesthesiologist: A primer on congenital malformations, pharmacogenetics, and proteomics. Anesth Analg 2010; Curriculum Vitae Myron Yaster, M.D. 9 111(5):1264-74. 19. Yaster M. Multimodal analgesia in children. Eur J Anaesthesiol 2010; 27(10):851-7. Invited Reviews, Editorials 1. Yaster M: Analgesia and anesthesia in neonates. J Pediatr 1987; 111:394-6. 2. Yaster M: Pain relief (editorial). Pediatrics 1995; 95:427-8. 3. Yaster M, Raphaely R: A festschrift for John J. Downes. Am J Anesthesiol 1996; 23:155. 4. Maxwell LG, Yaster M: The myth of conscious sedation. Arch Pediatr Adolesc Med 1996; 150(7):665-7. 5. Yaster M, Schechter N: Pain and human immunodeficiency virus infection in children. Pediatrics 1996; 98(3 Pt 1):455-6. 6. Maxwell, L.G. and Yaster, M.: Analgesia for neonatal circumcision: no more studies, just do it. 1999; Arch Pediatr Adolesc Med 153(5):444-5. 7. Yaster M: The pediatric sedation unit: a mechanism for safe sedation. Pediatrics 1999; 103:198-9. 8. Yaster M, Cravero JP. The continuing conundrum of sedation for painful and nonpainful procedures. J Pediatr 2004; 145:10-2. 9. Goodwin SR, Haberkern C, Crawford M, Lerman J, Mancuso T, Yaster M: Sickle cell and anesthesia: do not abandon well-established practices without evidence. Anesthesiology 2005; 103:205-7. 10. Nichols DG, Yaster M: Victims of our own success or quo vadis pediatric anesthesia? Anesth Analg 2007; 104:255-7. Published Abstracts 1. Yaster M, Simmons RS, Finkelstein BW, Pepple JM: Failure of IV nitroglycerin in hypotensive anesthesia in children: A double blind comparison. Anesthesiology 61: A423, 1984. 2. Yaster M: The dose response of fentanyl in neonatal surgery. Anesthesiology 63: A471, 1985. 3. Yaster M, AronoffD, Kornhauser DM, Pasternak LR, Jeffs RD: The pharmacokinetics of lidocaine during caudal anesthesia in children. Anesthesiology 63: A465, 1985. 4. Yaster M, Simmons RS, Buck JR, Azizkhan RG, Dudgeon DL, Haller JA: Hemodynamic effects of primary closure of omphalocele/gastroschisis in newborns. Anesthesiology 65: A449, 1986. 5. Maxwell LG, Harris AP, Gurtner GH: Penile nerve block reduces the physiologic stress of newborn circumcision. Anesthesiology 65: A385, 1986. 6. Yaster M, Koehler RC, Traystman RJ: Interaction of fentanyl and pentobarbital on Curriculum Vitae Myron Yaster, M.D. 10 cerebral peripheral hemodynamics in newborn lambs. Anesthesiology 67: A516, 1987. 7. Grayson RJ, Marino PN, Yaster M, Weis J, Kass DA: Is amrinone an inotrope in vivo? Assessment by end-systolic pressure volume relationships. Anesthesiology 67: A600, 1987. 8. Spear RM, Yaster M, Deshpande JK, Wetzel RC, Nichols DG: Rectally administered midazolam for preinduction sedation and induction of general anesthesia in small children. Anesthesiology 69: A742, 1988. 9. Yaster M, Berkowitz ID, Bender KS, Maxwell LG, Nichols DG: Rectally administered midazolam for preinduction of anesthesia in children. Anesthesiology 71: A1043, 1989. 10. Nichols DG, Yaster M, Deshpande JK, Helfaer M, Lynn A, Tobias J: Disposition and respiratory effects of intrathecal morphine in children. Anesthesiology 73: A1135, 1990. 11. Yaster M, Koehler RC, Traystman RJ: The cerebral and peripheral hemodynamic effects of epidural anesthesia in newborn lambs. Anesthesiology 75: A918, 1991. 12. Kost-Byerly S, Yaster M, Koehler RC, Traystman RJ: Failure of pancuronium and atropine to augment epinephrine induced tachycardia in halothane anesthetized newborn lambs. Anesthesiology 77: A1148, 1992. 13. Yaster M, Tobin JR, Billett C, Casella JF, Dover G: Epidural analgesia in the management of vaso-occlusive sickle cell crisis. Anesthesiology 79: A1133, 1993. 14. Kost-Byerly S, Greenberg RS, Yaster M: Colonization and infection rates of continuous epidural pediatric epidural catheters; a prospective study in children. Anesthesiology 79: A1132, 1993. 15. Kost-Byerly S, Tobin JR, Greenberg RS, Billett C, Yaster M: Continuous lidocaine epidural analgesia in children. Anesthesiology 81: A1131, 1993. 16. Yaster M, Koehler RC, Traystman RJ: Interaction of fentanyl and ketamine on cerebral peripheral hemodynamics in newborn lambs. Anesthesiology 81: A1330, 1994 17. Greenberg RS, Yaster M, Maxwell LG: Preinduction of anesthesia in children with midazolam using the Bioject jet injector. Anesthesiology 81: A1383, 1994. 18. Kost-Byerly S, Greenberg RS, Billett C, Khandwala R, Yaster M: Continuous lidocaine epidural analgesia in neonates. Anesthesiology 81: A1343, 1994. 19. Yaster M, Rich JB, Brandt J: Propofol blocks implicit and explicit memory and does not produce retrograde amnesia in children. Anesthesiology 83: A1132, 1995. 20. Zuckerberg A, Benzuly S, Andrade T, Yaster M. Continuous infusions of epidural lidocaine result in toxic plasma levels in children with sickle cell hemoglobinopathy. Anesthesiology 83: A1138, 1995. 21. Zuckerberg A, Luddy R, Yaster M. Epidural analgesia improves oxygenation in acute chest syndrome of sickle cell hemoglobinopathy. Anesthesiology 83: A1140, 1995. 22. Hastings L, Monitto C, Lenox C, Yaster M: CSF and plasma levels of fentanyl in children undergoing ventriculoperitoneal shunt surgery. Anesthesiology 87: A1063, 1997. 23. Monitto CL, Greenberg RS, Kost-Byerly S, Wetzel RC, Yaster M: Safety and efficacy of parent/nurse controlled analgesia in patients less than 6 years of age. Anesthesiology 89: Curriculum Vitae Myron Yaster, M.D. 11 A1324, 1998. 24. Schwengel DA, Berenholtz S, Kozlowski L, McGready J, Nichols DG, Yaster M: Peripherally inserted central catheters in pediatric surgical patients; a randomized, controlled, prospective trial. Anesthesiology 96: A1218, 2002. 25. Yaster M, Kaufmann SC, Bitzer S, Jackson EV Jr., Maxwell LG: Effects of a low-dose naloxone infusion on opioid-induced side effects and analgesia in children and adolescents treated with intravenous patient-controlled analgesia: a prospective, randomized, controlled, double-blind study Anesthesiology A, 1453, 2003 26. Johns RA, Liaw WJ, Yaster M, Zhang B, Tao YX: Evidence for the involvement of spinal cord glutamate transporters in the development of chronic inflammatory pain. Anesthesiology A, 1085, 2003. 27. Verghese ST, Hammer GB, Lavandosky G, Yaster M, Tobin JR: A multicenter, randomized study to determine the pharmacokinetics and pharmacodynamics of fenoldopam mesylate in pediatric patients. Anesthesiology A, 1445, 2003. 28. Lee BH, Pronovost P, Jackson EV, Yaster M. Discharge analgesic prescription errors in pediatrics: A preliminary study of 105 patients. Anesthesiology A, 1280, 2004. 29. Shaffner DH, Heitmiller ES, Maxwell LG, Hunt EA, Yaster M: Assessing the Knowledge of American Heart Association Cardiopulmonary Resuscitation Guidelines in Pediatric Anesthesiologists. Anesthesiology A, 1433, 2004 30. Kost-Byerly S, Jackson EV, Schwengel DA, Yaster M: Perioperative anesthetic management of newborn bladder exstrophy repair. Anesthesiology A, 1472, 2004. 31. Nelson KL, Shaffner, DH, Hunt EA, Yaster M, Heitmiller E: Pediatric cardiopulmonary arrest management in the operating room – results of a national survey. Anesthesiology A, 1648, 2007. 32. Nelson KL, Yaster M, Kost-Byerly S, Monitto C: Pediatric pain management – Results of a national survey of pediatric anesthesiologists. Anesthesiology A, 688, 2007. 33. Nelson KL, Yaster M, Kost-Byerly S, Monitto C. Patient controlled analgesia by proxy: results from a national survey. Anesthesiology A, 685, 2007. 34. Kost-Byerly S, Shue Z, Mathews RI, Gearhart JP, Yaster M: Perioperative anesthetic management of delayed or repeat bladder exstrophy repair Anesthesiology A, 696, 2007. 35. Tao Y-X, Guan Y, Yaster M, Raja SN: Genetic knockout and pharmacological inhibition of nNOS attenuate nerve injury-induced pain in mice. Anesthesiology A, 164, 2007. 36. Monitto CL, White E, Kost-Byerly S, Yaster M: Optimal sose of IV naloxone to ameliorate opioid induced side effects in children receiving IVPCA. Anesthesiology A 1609, 2008. 37. Williamson JL, Latham G, Yaster M, Heitmiller ES: Off-label drug use in pediatric anesthesia: A continuing conundrum. Anesthesiology A 789, 2008. 38. Yaster M, Singh OV, Guan Y, Raja SN, Tao Y-X: Proteome of synaptosome-associated proteins in spinal cord dorsal horn after peripheral nerve injury. Anesthesiology A 636, 2008 Curriculum Vitae Myron Yaster, M.D. 12 39. Kozlowski L, Colantuoni, E, White E, Yaster M, Kost-Byerly S: An analysis of analgesic use and pain assessment methods in a hospitalized pediatric population. Anesthesiology A 1551, 2009. 40. Yaster M, Park J, Huganir RL, Tao Y-X: Peripheral inflammation drives NMDAR/PKCdependent GluR2 internalization in dorsal horn neurons. Anesthesiology A 118, 2009. Book Chapters 1. Yaster M, Haller JA, Jr.: Multiple trauma in the pediatric patient. In: Rogers MC (Ed.): Textbook of Pediatric Intensive Care. Baltimore. Williams and Wilkins, 1987, pp. 12651322. 2. Yaster M, Maxwell LG: Pain management. Hoekelman RA, Friedman SB, Nelson NM, Seidel HM (Eds.): Primary Pediatric Care. 2nd edition. St. Louis, Mosby-Year Book, 1992, pp. 302-317. 3. Yaster M: Airway management. In: Nichols DG, Yaster M, Lappe DG, Buck JR (Eds.): Golden Hour: The Handbook of Advanced Pediatric Life Support. Mosby-Year Book, St. Louis, MO, 1991, pp. 9-46. 4. Yaster M: Pain control and sedation. In: Nichols DG, Yaster M, Lappe DG, Buck JR (Eds.): Golden Hour: The Handbook of Advanced Pediatric Life Support. Mosby-Year Book, St. Louis, MO, 1991, pp. 191-200. 5. Yaster M: Preoperative assessment of the newborn. In: Rogers M, Tinker J, Covino B, Longnecker D (Eds.): Principles and Practice of Anesthesiology. Mosby-Year Book, St. Louis, MO, 1991. 6. Yaster M: Anesthesia for newborn surgical emergencies. In: Rogers M, Tinker J, Covino B, Longnecker D, (Eds.): Principles and Practice of Anesthesiology. Mosby-Year Book, St. Louis, MO, 1991. 7. Yaster M, Bean JD, Tremlett M, Nicholas EJ, Rogers MC: Pain sedation, and postoperative anesthetic management in the pediatric intensive care unit. In: Rogers MC (Ed.): Textbook of Pediatric Intensive Care. 2nd edition. Williams and Wilkins, Baltimore 1992, pp. 1518-1570. 8. Yaster M, Nicholas EJ: Pain management in children. In: Rogers MC, Decker BC (Eds.): Current Practice in Anesthesiology. 2nd edition. Mosby-Year Book, Philadelphia, PA, 1991, pp. 242-250. 9. Yaster M: Gastroschisis. In: Stehling L. (Ed.): Common Problems in Pediatric Anesthesia. 2nd edition. Mosby-Year Book, St. Louis, MO, 1992, pp.19-26. 10. Yaster M, Maxwell LG: Opioid agonists and antagonist. In: Schecter NL, Berde CB, Yaster M (Eds.): Pain in Infants, Children, and Adolescents. Williams and Wilkins, Baltimore, MD, 1992, pp. 145-171. 11. Yaster M, Tobin JR, Maxwell LG: Local anesthetics. In: Schecter NL, Berde CB, Yaster M (Eds.). Pain in Infants, Children, and Adolescents. Williams and Wilkins, Baltimore, MD, 1992, pp. 179-194. Curriculum Vitae Myron Yaster, M.D. 13 12. Yaster M, Tobin J: Pain management in the pediatric intensive care unit. In: Critical Care State of the Art, Vol. 14. Society of Critical Care Medicine, Anaheim, 1993, 2:61-130. 13. Yaster M, Maxwell LG: Airway management. In: Nichols DG, Yaster M, Lappe DG, Haller JA, (Eds.): Golden Hour: The Handbook of Advanced Pediatric Life Support. 2nd edition. Mosby-Year Book, St. Louis, 1996, pp. 9-59. 14. Yaster M, Weigle CGM: Electrolyte, metabolic, and endocrine disorders. In: Nichols DG, Yaster M, Lappe DG, Haller JA, (Eds.): Golden Hour: The Handbook of Advanced Pediatric Life Support. 2nd edition. Mosby-Year Book, St. Louis, 1996, pp. 197-216. 15. Yaster M, Greenberg RS, Tobin JR: Pain control and sedation. In: Nichols DG, Yaster M, Lappe DG, Haller JA, (Eds.): Golden Hour: The Handbook of Advanced Pediatric Life Support. 2nd edition. Mosby-Year Book, St. Louis, 1996, pp. 325-344. 16. Helfaer MA, Yaster M: Pediatric drug formulary. In: Nichols DG, Yaster M, Lappe DG, Haller JA, (Eds.): Golden Hour: The Handbook of Advanced Pediatric Life Support. 2nd edition. Mosby-Year Book, St. Louis, 1996, pp. 555-605. 17. Yaster M, Wetzel RC. Pediatric anesthesia. In: Oldhalm KT, Colombani PM, Foglia RP (Eds.): Surgery of Infants and Children: Scientific Principles and Practice. LippincottRaven, Philadelphia, 1997, pp. 327-358. 18. Zuckerberg AL, Yaster M: Anesthesia for orthopedic surgery. In: Motoyama EK, Davis PJ (Eds.): Smith’s Anesthesia for Infants and Children. Mosby Year Book, St. Louis, 1996, pp 605-632. 19. Maxwell LG, Yaster M: Preoperative assessment. In: Hoekelman RA, Friedman SB, Nelson NM, Seidel HM, Weitzman ML (Eds.): Primary Pediatric Care. Mosby Year Book, St. Louis, 1997, pp. 98-108. 20. Yaster M, Kost-Byerly S, Maxwell LG: Management of acute pain in children. In: Hoekelman RA, Friedman SB, Nelson NM, Seidel HM, Weitzman ML (Eds.): Primary Pediatric Care. Mosby Year Book, St. Louis, 1997, pp. 98-108. 21. Yaster M, Paidas CN, Maxwell LG: Postoperative management of the pediatric outpatientsurgical and anesthetic aspects. In: Hoekelman RA, Friedman SB, Nelson NM, Seidel HM, Weitzman ML (Eds.): Primary Pediatric Care. Mosby Year Book, St. Louis, 1997, pp. 98-108. 22. Yaster M: Nonsteroidal antiinflammatory drugs. In: Yaster M, Krane EJ, Kaplan R, Coté C, Lappe DG (Eds.): The Handbook of Pediatric Pain Management and Sedation. Mosby Year Book, St. Louis, 1997, pp 19-27. 23. Yaster M, Karolinski K, Maxwell L: Opioid agonists and antagonists. In: Yaster M, Krane EJ, Kaplan R, Coté C, Lappe DG (Eds.): The Handbook of Pediatric Pain Management and Sedation. Mosby Year Book, St. Louis, 1997, pp. 29-49. 24. Yaster M: Local anesthetics. In: Yaster M, Krane EJ, Kaplan R, Coté C, Lappe DG (Eds.): The Handbook of Pediatric Pain Management and Sedation. Mosby Year Book, St. Louis, 1997, pp. 51-71. 25. Yaster M, Kost-Byerly S: Adjuvant analgesics. In: Yaster M, Krane EJ, Kaplan R, Coté C, Lappe DG (Eds.): The Handbook of Pediatric Pain Management and Sedation. Mosby Curriculum Vitae Myron Yaster, M.D. 14 26. Yaster M, Billett C, Monitto C: Intravenous patient controlled analgesia. In: Yaster M, Krane EJ, Kaplan R, Coté C, Lappe DG (Eds.): The Handbook of Pediatric Pain Management and Sedation. Mosby Year Book, St. Louis, 1997, pp. 89-111. 27. Yaster M, Andresini, JA, Krane E: Epidural analgesia. In: Yaster M, Krane EJ, Kaplan R, Coté C, Lappe DG (Eds.): The Handbook of Pediatric Pain Management and Sedation. Mosby Year Book, St. Louis, 1997, pp.113-146. 28. Krane E, Yaster M: Transition to less invasive therapy. In: Yaster M, Krane EJ, Kaplan R, Coté C, Lappe DG (Eds.): The Handbook of Pediatric Pain Management and Sedation. Mosby Year Book, St. Louis, 1997, pp.147-162. 29. Yaster M: Peripheral nerve blockade. In: Yaster M, Krane EJ, Kaplan R, Coté C, Lappe DG (Eds.): The Handbook of Pediatric Pain Management and Sedation. Mosby Year Book, St. Louis, 1997, pp. 163-188. 30. Lin Y-C, Krane E, Yaster M: Challenging pain problems. In: Yaster M, Krane EJ, Kaplan R, Coté C, Lappe DG (Eds.): The Handbook of Pediatric Pain Management and Sedation. Mosby Year Book, St. Louis, 1997, pp. 191-218. 31. Kaplan R, Greenberg R, Yaster M: Sedation for diagnostic and therapeutic procedures. In: Yaster M, Krane EJ, Kaplan R, Coté C, Lappe DG (Eds.): The Handbook of Pediatric Pain Management and Sedation. Mosby Year Book, St. Louis, 1997, pp.273-308. 32. Kaplan R, Yaster M: Sedation documentation and record keeping. In: Yaster M, Krane EJ, Kaplan R, Coté C, Lappe DG (Eds.): The Handbook of Pediatric Pain Management and Sedation. Mosby Year Book, St. Louis, 1997, pp. 321-343. 33. Yaster M, Coté C: Sedatives, hypnotics, anxiolytics, and amnestics. In: Yaster M, Krane EJ, Kaplan R, Coté C, Lappe DG (Eds.): The Handbook of Pediatric Pain Management and Sedation. Mosby Year Book, St. Louis, 1997, pp. 345-374. 34. Yaster M: General anesthesia. In: Yaster M, Krane EJ, Kaplan R, Coté C, Lappe DG (Eds.): The Handbook of Pediatric Pain Management and Sedation. Mosby Year Book, St. Louis, 1997, pp. 375-398. 35. Yaster M, Maxwell L: Fasting and prophylaxis guidelines. In: Yaster M, Krane EJ, Kaplan R, Coté C, Lappe DG (Eds.): The Handbook of Pediatric Pain Management and Sedation. Mosby Year Book, St. Louis, 1997, pp. 399-407. 36. Yaster M, Coté Charles: Monitoring and vigilance aids. In: Yaster M, Krane EJ, Kaplan R, Coté C, Lappe DG (Eds.): The Handbook of Pediatric Pain Management and Sedation. Mosby Year Book, St. Louis, 1997, pp. 409-421. 37. Yaster M: Recovery from sedation. In: Yaster M, Krane EJ, Kaplan R, Coté C, Lappe DG (Eds.): The Handbook of Pediatric Pain Management and Sedation. Mosby Year Book, St. Louis, 1997, pp. 423-433. 38. Yaster M, Shaffner DH, Schleien C: Cardiopulmonary resuscitation. In: Yaster M, Krane EJ, Kaplan R, Coté C, Lappe DG (Eds.): The Handbook of Pediatric Pain Management and Sedation. Mosby Year Book, St. Louis, 1997, pp. 435-457. Curriculum Vitae Myron Yaster, M.D. 15 39. Schwengel D, Elwood T, Yaster M: Sedation for radiology and radiation therapy. In: Yaster M, Krane EJ, Kaplan R, Coté C, Lappe DG (Eds.): The Handbook of Pediatric Pain Management and Sedation. Mosby Year Book, St. Louis, 1997, pp. 461-479. 40. Yaster M, Friedman R: Diagnostic evaluation of congenital heart disease. In: Yaster M, Krane EJ, Kaplan R, Coté C, Lappe DG (Eds.): The Handbook of Pediatric Pain Management and Sedation. Mosby Year Book, St. Louis, 1997, pp. 527-543. 41. Yaster M: Acute pain management reimbursement: Issues, options, and strategies. In: Yaster M, Krane EJ, Kaplan R, Coté C, Lappe DG (Eds.): The Handbook of Pediatric Pain Management and Sedation. Mosby Year Book, St. Louis, 1997, pp. 567-577. 42. Yaster M: Evaluation of the neonate. In: Longnecker DE, Tinker JH, Morgan GE (Eds.): Principles and Practice of Anesthesiology, Vol. 1. 2nd edition. Mosby Year Book, St. Louis, 1998, pp.426-437. 43. Yaster M: Anesthesia for surgical emergencies in newborns. In: Longnecker DE, Tinker JH, Morgan GE (Eds.): Principles and Practice of Anesthesiology, Vol. 2. 2nd edition. Mosby Year Book, St. Louis, 1998, pp. 2058-2078. 44. Yaster M, Galloway K: Management of Acute Pain. In: Yaster M (Ed.): Pediatric Anesthesia, Problems in Anesthesiology. Lippincott Williams and Wilkins, Philadelphia, 10:4, 1998, pp 507-520. 45. Maxwell LG, Yaster M: Common postoperative problems. In: Yaster M. (Ed): Pediatric Anesthesia, Problems in Anesthesiology. Lippincott Williams and Wilkins, Philadelphia, 10:4, 1998, pp 466-577. 46. Yaster M, Kost-Byerly S, Maxwell LG: Pediatric pain management. In: Bissonnette B, Dalens B (Eds.): Pediatric Anesthesia: Principles and Practice. McGraw Hill, New York, 2001, pp. 705-721. 47. Yaster M, Hardart RA: Pediatric Pan Management. In: Raj PP (Ed.): Textbook of Regional Anesthesia. Churchill Livingstone, New York, 2002, pp.1009-1032. 48. Yaster M, Maxwell LG, Kaplan RF: The anesthesiologist and sedation: Who, What, When, Where, and Why? In: Yemen TA (Ed.): Pediatric Anesthesia Handbook. McGraw Hill, New York, 2002, pp 389-399. 49. Yaster M: Clinical pharmacology. In: Schecter NL, Berde CB, Yaster M (Eds.): Pain in Infants, Children, and Adolescents. Lippincott Williams and Wilkins, Philadelphia, PA, 2003, pp 71-84. 50. Yaster M, Kost-Byerly S, Maxwell LG: Opioid agonists and antagonist. In: Schecter NL, Berde CB, Yaster M (Eds.): Pain in Infants, Children, and Adolescents. Lippincott Williams and Wilkins, Philadelphia, PA, 2003, pp 181-224. 51. Yaster M, Tobin JR, Maxwell LG: Local anesthetics. In: Schecter NL, Berde CB, Yaster M (Eds.): Pain in Infants, Children, and Adolescents. Lippincott Williams and Wilkins, Philadelphia, PA, 2003, pp 241-264. 52. Desparmet JF, Hardart RA, Yaster M: Central blocks in children and adolescents. In: Schecter NL, Berde CB, Yaster M (Eds.): Pain in Infants, Children, and Adolescents. Lippincott Williams and Wilkins, Philadelphia, PA, 2003, pp 339-362. Curriculum Vitae Myron Yaster, M.D. 16 53. Yaster M, Maxwell LG, Kost-Byerly S: Opioids in the management of acute pediatric pain. In: Malviya S, Naughton NN, Tremper KK (Eds.): Sedation and Analgesia for Diagnostic and Therapeutic Procedures. Humana Press, Totowa, NJ, 2003, pp 153-190. 54. Yaster M, Kost-Byerly S: Acute pain management in children. In: Hadzic A (Ed.): Textbook of Regional Anesthesia and Acute Pain Management. McGraw Hill Medical, New York, 2007, 768-778. 55. Yaster M, Elliott RA: Preoperative assessment of the newborn. In: Longnecker DE, Brown DL, Newman MF, Zapol WM (Eds.): Anesthesiology. McGraw Hill, New York, 2008, 300-309. 56. Yaster M, Rossberg MI: Anesthesia for newborn surgical emergencies. In: Longnecker DE, Brown DL, Newman MF, Zapol WM (Eds.): Anesthesiology. McGraw Hill, New York, 2008, 1502-1519. 57. Yaster M, Easley RB, Brady KM: Pain and sedation management in the critically ill child. In: Rogers’ Textbook of Pediatric Intensive Care. 4th edition. Lippincott Williams and Wilkins, Philadelphia, 2008, 136-165. 58. Schwengel DA, Paidas CN, Yaster M: Initial assessment. In: Nichols DG, Yaster M, Schleien CL, Paidas CN (Eds.): Golden Hour: The Handbook of Advanced Pediatric Life Support. 3rd edition. Elsevier Mosby, Philadelphia, 2011, pp. 1-7. 59. Lancaster CT, Yaster M: Airway management. Nichols DG, Yaster M, Schleien CL, Paidas CN (Eds.): Golden Hour: The Handbook of Advanced Pediatric Life Support. 3rd edition. Elsevier Mosby, Philadelphia, 2011, pp. 8-46. 60. Oliva-Hemker M, Colombani PM, Yaster M: Gastrointestinal emergencies. In: Nichols DG, Yaster M, Schleien CL, Paidas CN (Eds.): Golden Hour: The Handbook of Advanced Pediatric Life Support. 3rd edition. Elsevier Mosby, Philadelphia, 2011, pp. 181-199. 61. Zuckerberg AL, Yaster M, Nichols DG: Hematologic emergencies. In: Nichols DG, Yaster M, Schleien CL, Paidas CN (Eds.): Golden Hour: The Handbook of Advanced Pediatric Life Support. 3rd edition. Elsevier Mosby, Philadelphia, 2011, pp. 208-222. 62. Haun S, Yaster M, Nichols DG: Nontraumatic Stupor and Coma. In: Nichols DG, Yaster M, Schleien CL, Paidas CN (Eds.): Golden Hour: The Handbook of Advanced Pediatric Life Support. 3rd edition. Elsevier Mosby, Philadelphia, 2011, pp. 260-268. 63. Yaster M: Pain Control and Sedation Management. In: Nichols DG, Yaster M, Schleien CL, Paidas CN (Eds.): Golden Hour: The Handbook of Advanced Pediatric Life Support. 3rd edition. Elsevier Mosby, Philadelphia, 2011, pp. 329-348. Book Editor 1. Nichols DG, Yaster M, Lappe DG, Buck JR (eds): Golden Hour: The Handbook of Advanced Pediatric Life Support. Mosby-Year Book, St. Louis, MO, 1991. 2. Schechter NL, Berde CB, Yaster M (Eds.): Textbook: Pain in Infants, Children and Adolescents. Williams and Wilkins, Baltimore, MD, 1992. 3. Nichols DG, Yaster M (Editor-in-Chief), Lappe DG, Haller JA, (Eds.): Textbook: Golden Curriculum Vitae Myron Yaster, M.D. 17 Hour: The Handbook of Advanced Pediatric Life Support. 2nd edition. Mosby Year Book, Inc., St. Louis, 1996. 4. Yaster M, Krane EJ, Kaplan R, Coté C, Lappe DG (Eds.): The Handbook of Pediatric Pain Management and Sedation. Mosby Year Book, St. Louis, 1997. 5. Schecter NL, Berde CB, Yaster M, (Eds.) Textbook: Pain in Infants, Children, and Adolescents. 2nd edition. Lippincott Williams and Wilkins, Philadelphia, PA, 2003. 6. Nichols DG. Rogers’ Textbook of Pediatric Intensive Care. 4th edition. Lippincott Williams and Wilkins, Philadelphia, 2008. 7. Nichols DG, Yaster M, Schleien CL, Paidas CN: Textbook: Golden Hour: The Handbook of Advanced Pediatric Life Support. 3rd edition. Elsevier Mosby Inc. Philadelphia, 2011. Electronic Media 1. 2. E-Sedation: A credentialing course for the faculty and housestaff of JHU 9 hour course: 7 hour internet, 2 hour in simulation center Pain Management for Health Care Professionals-JHU 1/2 hour internet course Extramural Sponsorship (current, previous) Title: Rett Syndrome: Genetics, Pathogenesis and Search for Markers Principal Investigator: Sakkubai Naidu, M.D. Sponsor: NIH -1P01HD24448 Total Project Period: 7/1/96 -2006 Total Direct Costs: $142,709 Faculty Role: Co-Investigator % of Effort: 3% Title: Behavior and Neurobiological Correlates of HPRT Deficiency Principal Investigator: James C. Harris, M.D Sponsor: NICHD R01HD33095 Total Project Period: 4/1/98 - 2004 Total Direct Costs: $244,174.00 Faculty Role: Co- Investigator % of Effort: 2.5% Title: USAA3119 A randomized study of Ultiva versus halothane in neonates and infants undergoing pyloric stenosis. Principal Investigator: Myron Yaster, M.D. Sponsor: Glaxo Wellcome Total Project Period: 2/98-2000 Total Direct Costs: $36,000 Faculty Role: Principal Investigator Title: A phase 1 study of an adeno-associated virus CFTR gene vector in adult CF patients with Curriculum Vitae mild lung disease Principal Investigator: Sponsor: Total Project Period: Total Direct Costs: Faculty Role: % of Effort: Myron Yaster, M.D. 18 Pamela L. Zeitlin, M.D, Ph.D. Targeted Genetics Incorporated 7/26/99 - 6/30/2002 $31,200.00 Co- Investigator 2.5% Title: Evaluation and safety profile and clinical effectiveness of oral tramadol hydrochoride tablets for the treatment of postsurgical pain in children and adolescents aged 7-16 years. Prototolc Tram-Peds-005, phase 2 Principal Investigator: Myron Yaster, M.D. Sponsor: R. W. Johnson Pharmaceutical Research Institute and Parexel International Corporation Total Project Period: 5/99-2001 Total Direct Costs: $30,000 Faculty Role: Principal Investigator Title: A pharmacokinetic and clinical evaluation of continuous lumbar epidural infusion of ropivacaine for 24-72 hours in 1-12 year old children for postoperative pain management after major surgery Principal Investigator: Myron Yaster, M.D. Sponsor: Astra Pain Control SP-ROA-0015 Total Project Period: 4/98 Total Direct Costs: $60,000 Faculty Role: Principal Investigator Title: A multicenter, randomized study to determine the pharmacokinetics and pharmacodynamics of fenoldopam mesylate in pediatric subjects. Clinical Study Protocol No. 2000-027 Principal Investigator: Myron Yaster, M.D. Sponsor: Abbott Laboratories Total Project Period: 10/2001-10/2002 Total Direct Costs: $38,000 Title: A Multicenter, Open-Label, Multiple-Dose Study of the Conversion From Immediate Release (OxyIR®) to Controlled Release Oxycodone (OxyContin®) to Evaluate Pharmacokinetics and to Characterize Safety and Efficacy in Pediatric Patients 6 to ≤ 16 Years of Age. Clinical Study Protocol No. OXP3004 Treatment Phase; OXP3004 Extension Phase Principal Investigator: Myron Yaster, M.D. Sponsor: Purdue Pharma L.P. – Stamford, CT Total Project Period: 10/2003-10/2004 Total Direct Costs: $50,000 Faculty Role: Principal Investigator Curriculum Vitae Myron Yaster, M.D. 19 Title: Multi-center, double blind, randomized, dose ranging study, in pediatric patients 5 to </= 16 years of age receiving morphine as standard supplemental pain medication, to evaluate pharmacokinetics, safety and efficacy of oxy pediatric liquid (1mg/ml) versus placebo in the treatment of acute moderate to severe pain. Clinical Study Protocol No. OXP 3003 Principal Investigator: Myron Yaster, M.D. Sponsor: Purdue Pharma L.P. – Stamford, CT Total Project Period: 10/2003-10/2004 Total Direct Costs: $50,000 Faculty Role: Principal Investigator Title: A Multi-Center, In-Patient, Open-Label, Dose-Ranging Study to Characterize the Pharmacokinetics and Safety of an Oral Liquid Formulation of Oxycodone in Patients from Birth to 4 Years of Age, Who Require Opioid Analgesia. Clinical Study Protocol No. OXP 1005 Principal Investigator: Myron Yaster, M.D. Sponsor: Purdue Pharma L.P. – Stamford, CT Total Project Period: 10/2003-10/2004 Total Direct Costs: $50,000 Faculty Role: Principal Investigator Title: A randomized, double-blind, placebo controlled pharmacokinetic study evaluating the SCAINE™ patch for induction of local anesthesia prior to vascular access procedures in pediatric patients. Protocol No. 20-01 Principal Investigator: Myron Yaster, M.D. Sponsor: ZARS Corporation Total Project Period: 1/2002-1/2004 Total Direct Costs: $20,000 Title: Effects of a low dose naloxone infusion on analgesia and opioid induced side effects in children treated with patient controlled analgesia: a randomized, double blind, controlled study. Protocol number 00-06-13-03 Principal Investigator: Myron Yaster, M.D. Sponsor: Blaustein Pain Foundation Total Project Period: 10/2002-10/2004 Total Direct Costs: $50,000 Faculty Role: Principal Investigator Title: The management of postoperative craniotomy pain in adults: A prospective, randomized controlled trial. Principal Investigator: Myron Yaster, M.D. Sponsor: Blaustein Pain Foundation Total Project Period: 10/2002-10/2004 Total Direct Costs: $30,000 Faculty Role: Principal Investigator Title: Phosphatidylinositol 3-kinase/protein kinase B are key mediators in the development of Curriculum Vitae Myron Yaster, M.D. 20 chronic morphine tolerance. Sponsor Blaustein Pain Foundation Principal Investigator: Myron Yaster, M.D. Sponsor: Blaustein Pain Foundation Total Project Period: 10/2010-10/2012 Total Direct Costs: $40,000 Faculty Role: Principal Investigator Title: An open label, non randomized, multicenter, ascending dose by age, single and multidose evaluation of the effectiveness, safety, and tolerability of oral liquid oxymorphone immediate release for acute postoperative pain in pediatric subjects. Principal Investigator: Myron Yaster, M.D. Sponsor: Endo Pharmaceuticals Incorporated, Chadds Ford, PA Total Project Period: 10/2011-10/2013 Total Direct Costs: $50,000 Faculty Role: Principal Investigator EDUCATIONAL ACTIVITES Teaching Activities 1984 - 2006 Faculty: Advanced Pediatric Life Support Course (APLS) The Johns Hopkins University School of Medicine and The Johns Hopkins Pediatric Trauma Center, Baltimore, Maryland "Pediatric Airway Management" "The Management of Acute Airway Obstruction" (Epiglottitis-Croup) "The Management of Childhood Respiratory Failure" "The Management of Medical Encephalopathies in Children” “The Management of Stupor and Coma" “The Management of Status Epilepticus” "Pediatric Pain Management" "Conscious and Deep Sedation-Principles of Safe Practice" Oct 1991-93 Faculty: Annual Meeting of the American Society of Anesthesiologists Refresher Course Lectures, San Francisco, New Orleans, Washington, D.C. "Pediatric Regional Anesthesia" Oct 1992 Faculty: American Society of Anesthesiologists San Francisco, New Orleans, Washington, D.C., Atlanta, San Diego, Orlando "Problem Based Learning: Pediatrics" Nov 1992 Faculty: Advanced Pediatric Life Support Course (APLS), The Johns Hopkins University School of Medicine, SAIDIA, and the Kenyatta National Hospital, Nairobi, Kenya "Pediatric Airway Management" "The Management of Acute Airway Obstruction" (Epiglottitis-Croup) "Fluids and Electrolytes and the Management of Shock" "The Management of Medical Encephalopathies in Children--The Management of Stupor and Coma" "The Management of Head Trauma" Curriculum Vitae Myron Yaster, M.D. 21 "The Medical Management of Seizures" May 1993 Faculty: Society of Critical Care Medicine Annual Meeting, New York City "The Management of Pain in the Pediatric Intensive Care Unit" Spring 1993 Faculty: American Academy of Pediatrics Annual Meeting: Philadelphia, Chicago, New York City, Atlanta "Principles and Practice of Pediatric Sedation and Pain Management" “Palliative Care–Pain Management for the Terminally Ill” “The Management of Pain in the Newborn Infant” Nov 1993 Faculty: Advanced Pediatric Life Support Course (APLS) The Johns Hopkins University School of Medicine, SAIDIA, and the Korle-Bu National Hospital, Accra, Ghana Sept 1995 Faculty and Course Director: Advanced Pediatric Life Support (APLS), The Johns Hopkins University School of Medicine, F.D.Roosevelt Hospital Banska Bystricia, Slovakia, and the Slovak Society of Medicine, Bratislava and Banska Bystricia Slovakia Oct 1995 Faculty The Annual Meeting of Society for Pediatric Anesthesia “Opioid Anesthesia in the Newborn” Feb 1996 Faculty The Annual Meeting of the Society for Pediatric Anesthesia, San Antonio, Tampa, Las Vegas “The Nuts and Bolts of Setting Up a Pediatric Pain Service” “Workshop: Advanced Nerve Blocks and Regional Anesthetic Techniques” “Workshop: Fiberoptic Laryngoscopy for the Difficult Pediatric Airway” June 1996 Faculty 17th Annual meeting of the Israel Society of Anesthesiologists “Pain Management in Children” “Pediatric Regional Anesthesia” Oct 1996 Faculty Annual Meeting of the American Pain Society, Washington DC “The Management of Pediatric Pain” Dec 1996 Faculty New York Post-Graduate Assembly “The Management of Postoperative Pediatric Pain” Dec 1997 Faculty New York Post-Graduate Assembly “Anesthesia for Pediatric Spine Surgery” Dec 1997 Faculty 19th Annual Meeting of the Puerto Rican Society of Anesthesiologists “The Management of Postoperative Pediatric Pain” “Common Post-Operative Problems” “Conscious Sedation, MAC, and General Anesthesia for Pediatric Patients Outside of the Operating Room–How, Why, What, When, and Where?” May 1998 Children in Pain Meeting the Challenge. Children’s Hospital of Michigan (Wayne Curriculum Vitae Myron Yaster, M.D. 22 State University). Keynote speaker: Pediatric Pain Management: State of the Art April 1998 Faculty and Course Director: Advanced Pediatric Life Support (APLS), The Johns Hopkins University School of Medicine, Hungarian Society of Medicine, Gyor and Budapest, Hungary June 1998 Faculty, 24th Annual Meeting of the Mexican Society of Anesthesiologists “The Management of Postoperative Pediatric Pain” “Preoperative Management of the Pediatric Patient” “Common Post-operative Problems in the Pediatric Patient” Sept 1998 Faculty, Annual Meeting of the Maryland Chapter of the American Academy of Pediatrics “Pain and Sedation Management for the Pediatric Patient” Dec 1998 The Magill Lecture, Imperial College of Science, Technology, and Medicine, Chelsea and Westminister Hospital and the Hammersmith Hospital, London UK “Common Post-Operative Problems in the Pediatric Patient” “Acute Pain Management in the Pediatric Patient” May 1999 Children in Pain: Advancing the practice of pain management, Children’s Hospital of Michigan, University of Michigan and Wayne State University School of Medicine. “The Physiology of Pain” Oct 1999 Annual meeting of the Society for Pediatric Anesthesia, Dallas TX “Pediatric Regional Anesthesia” Feb 2000 Faculty, The Annual Meeting of Society for Pediatric Anesthesia “The Perioperative Management of the Child with Sickle Cell Anemia ” Feb 2000 Faculty, The Annual Meeting of Society of Critical Care Medicine “Regional Anesthesia in the Management of Pediatric Critically Ill Children” March 2000 Faculty and Course Director: Advanced Pediatric Life Support (APLS), The Johns Hopkins University School of Medicine, Athens Greece Sept 2000 Faculty and Course Director: Sedation Management for Painful and Non Painful Procedures in Children and Adults: A Core Course for Medical, Nursing, and Dental Practitioners, Johns Hopkins University School of Medicine, Baltimore, MD Oct 2000 Faculty American Academy of Pediatrics Annual Meeting Chicago IL “The Management of Pain and Sedation in the Pediatric Patient” May 2001 Course Director: Pain Management: A Core Course for Medical, Nursing, and other Health Care Professionals, Johns Hopkins University School of Medicine, Baltimore, MD Annual Meeting American Society of Anesthesiologists: Oct 2001 Curriculum Vitae Myron Yaster, M.D. 23 Workshop on Regional Anesthesia: Pediatric Regional Anesthesia October 2001 Faculty, The Annual Meeting of Society for Pediatric Anesthesia “Pain Management: Meeting the Hospital JCAHO Requirements on a Budget” Nov 2001 Faculty, Seventh Annual Advances in Physiology and Pharmacology in Anesthesia and Critical Care, Wake Forest University School of Medicine “Postoperative Pain Management in Children” May 2002 Alumni Association College of Medicine State University of New York Health Science Center at Brooklyn Special recognition award in pediatric anesthesia and critical care medicine “Pain Management in infants, children, and adults” April 2004 World Congress of Anesthesia Pediatric Satellite Meeting, Bordeaux France “The Management of Pediatric Pain” May 2004 The Ralph Waters Visiting Professorship, University of Wisconsin, Madison WI “Neural Blockade in the Pediatric Patient” “Anesthesia for the newborn infant” October 2004 Refresher Course Faculty, 2004 Annual Meeting American Society of Anesthesiologists Las Vegas, Nevada “The Management of Acute Pediatric Pain” August 2005 Dannemiller Memorial Education Foundation “The Management of Acute Pediatric Pain” “The Management of Chronic Pediatric Pain” Sept 2005 Course director: Pediatric Intensive Care Unit/Pediatric anesthesiology 2005 update and state of the art. Johns Hopkins Hospital Baltimore MD “The Management of Pain and Sedation in the Pediatric Intensive Care Unit: Where We Are and Where Are We Going” Sept 2005 The Kaplan Memorial Lecture: Children’s Mercy Hospital, Kansas City, MO “Pediatric Pain Management ” October 2005 Refresher Course Faculty, 2005 Annual Meeting American Society of Anesthesiologists Atlanta, Georgia “The Management of Acute Pediatric Pain” Faculty, Clinical Workshop “Pediatric Regional Anesthesia” Faculty, Clinical Forum “Medical Genetics for the Anesthesiologist” October 2005 Faculty, 19th Annual Meeting North American Cystic Fibrosis Conference Baltimore MD “Acute Pain Management” “Tolerance, Dependence, and Addiction” May 2006 Visiting Professor Department of Anesthesiology University of Washington, Curriculum Vitae Myron Yaster, M.D. 24 Seattle WA “Six Sigma and Pediatric Pain Management-Error Reduction Improving the Quality of Care” “Proteomics: A Primer for the Anesthesiologist” June 2006 The James Phythyon MD Memorial Lecture: Vanderbilt University “Proteomics: A Primer for the Anesthesiologist” October 2006 Refresher Course Faculty, 2006 Annual Meeting American Society of Anesthesiologists Chicago, IL “The Management of Acute Pediatric Pain” Faculty, Clinical Workshop “Pediatric Regional Anesthesia” Faculty, Clinical Forum “Medical Genetics for the Anesthesiologist” Faculty, Clinical Forum “10 best papers 2006" Nov 2006 The Donlin Long Pain Service Award Lecture, Dean’s Lecture, Johns Hopkins University School of Medicine, Baltimore MD “Pediatric Pain Management: Past, Present, and Future” April 2007 Faculty, Children of the World Anesthesia Foundation, Mexico City “The Management of Pediatric Pain” “Anesthesia for the newborn infant” “Primer: Perioperative Fluid Management for the Pediatric Patient” Oct 2007 Refresher Course Faculty, 2007 Annual Meeting American Society of Anesthesiologists San Francisco, CA “The Management of Acute Pediatric Pain” Faculty, Clinical Workshop “Pediatric Regional Anesthesia” Luncheon Panel: “Intravenous v regional techniques for postoperative analgesia in the pediatric patient” Dec 2007 Faculty, Annual meeting New York State Society of Anesthesiologists Post Graduate Assembly New York City “10 things you have to know before you anesthetize a child” Sep 2008 The 5th Annual Josephine “Pena” Templeton Honorary Lecture, Children’s Hospital of Philadelphia, Philadelphia PA “The management of post craniotomy pain: a case study in how to conduct a clinical research trial” “Proteomics: A Primer for the Anesthesiologist” Oct 2008 Faculty, key note speaker, Annual Meeting of the Society for Pediatric Anesthesia, Orlando FL “Proteomics: A Primer for the Anesthesiologist” Nov 2008 Visiting Professor Department of Anesthesiology State University of New York, Downstate Medical Center, Brooklyn New York “Six Sigma and Pediatric Pain Management-Error Reduction Improving the Curriculum Vitae Myron Yaster, M.D. 25 Quality of Care” “The Management of Pediatric Pain” Feb 2009 The Digby Leigh Lecture: 47th Clinical Conference in Pediatric Anesthesiology, Children’s Hospital of Los Angeles, Anaheim, CA “Newer perspectives in managing the complication of opioids” May 2009 Faculty of the 1st Sino-American World Conference on Pediatric Anesthesia, Beijing China “The Management of Pediatric Pain” “Anesthesia for the newborn infant” March 2010 Faculty, key note speaker, Winter Meeting of the Society for Pediatric Anesthesia, San Antonio Texas “The management of post craniotomy pain: a case study in how to conduct a clinical research trial” Dec 2010 First annual Charles Beattie, PhD, MD Memorial Lecture, New York University School of Medicine, New York, NY “The management of post craniotomy pain: a case study in how to conduct a clinical research trial” Sept 2011 Visiting Professor Departments of Pediatrics and Anesthesiology Primary Children’s Hospital, Salt Lake City UT “Six Sigma and Pediatric Pain Management-Error Reduction Improving the Quality of Care” Twenty-fifth Annual Meeting Society for Pediatric Anesthesia Chicago IL “The History of Newborn Anesthesia: Past, Present, and Future” Oct 2011 Curriculum Vitae Myron Yaster, M.D. 26 Mentoring Fellowship Participants PICU Fellows Alice D. Ackerman J. Michael Dean John Gordon William D. Hayden Carl Weigele Kristen Nelson PICU/Anesthesia Fellows Pediatric Anesthesia Steven. D Barnes Ivor D. Berkowitz Ken Brady Anna Brown Alan G. Britten David Cordry Blaine Easley James L. Fackler James J. Fehr Randy Flick Robert S. Greenberg Steven Hayes Laura Hastings Steven Hayes Mark A. Helfaer Sapna Kudchadkar W. Casey Lenox Lynn D. Martin James J. McCloskey Michael E. Nemergut Dolores B. Njoku Reuben Pasternak Russ A. Sauder Larry Schwartz Jamie Schwartz Charles Scheien Deborah Schwengel Nancy Setzer Hal Shaffner Jay Shayvitz Linda K . Snelling Robert W. Spear Joseph D. Tobias Joseph R. Tobin Julie Williamson Aaron Zuckerberg Jolene D. Bean Karen S. Bender Christine Chen Richard Elliot Thomas Elwood Allison Fernandez Karen Galloway Richard Hardart Andrew Heath Eric Jackson, Jr. Sandra Kaufman Sabine Kost-Byerly Greg Latham Helen Lee Jennifer Lee Michael Lee Sharon Liu Christine Mai Sally Masey Richard Marn Lynne G. Maxwell Maureen Murphy Elizabeth Nicholas Winston Ota James L. Robotham Allison Kinder-Ross Devin Sanders Veronica Szabo Brian K. Tabata Michael Tremlett Richard Vax Daniel Woodward Charles Zahakala Curriculum Vitae Myron Yaster, M.D. 27 Editorial Activities Edited Festschrift for John J. Downes, MD for the American Journal of Anesthesiology 23; 1996 Editor Pediatric Anesthesia Problems in Anesthesia 10; 4, 1998 Lippincott Williams and Wilkins Editor Acute Pain Management Pediatric Clinics of North America published in June 2000 Journal Peer Review Activities Anesthesiology Anesthesia and Analgesia Archives of Pediatrics and Adolescent Medicine Critical Care Medicine Journal of Pediatrics Pain Pediatrics Journal of Pain and Symptom Management Journal of Regional Anesthesia and Pain Management Military Service None Licensure Pennsylvania Maryland Board Certification 4/83 5/86 7/87 American Board of Anesthesiology American Board of Pediatrics Pediatric Critical Care Medicine Professional Societies (membership): l979 1979 l983 American Society of Anesthesiology International Anesthesia Research Society Society of Critical Care Medicine Professional Societies (membership): 1986 1989 Society for Pediatric Anesthesia International Association for the Study of Pain Curriculum Vitae Myron Yaster, M.D. 28 1991 Association of University Anesthesiologists 1993 International Trauma Anesthesia and Critical Care Society 1996 Fellow, American Academy of Pediatrics 174511 2007 Congenital Cardiac Anesthesia Society 2011 Foundation for Anesthesia Education and Research Academy of Research Mentors in Anesthesiology Other Professional Accomplishments 1974 Summa Cum Laude, Brooklyn College of the City University of New York l977 Cum Laude, College of Medicine - Downstate Medical Center, State University of New York 1986 - 1988 President, Society for Pediatric Anesthesia 1987 - 1992 Board of Directors American Academy of Pediatrics Anesthesiology Section 1988 - 1992 Board of Directors, Society for Pediatric Anesthesia 1992 1992 - 2000 Committee on Pediatric Anesthesia, American Society of Anesthesiologists 1997 - 2000 Section on Anesthesiology Executive Committee- American Academy of Pediatrics 2000- Procedural Sedation Committee Johns Hopkins Hospital 2002- 2004 State of Maryland Advisory Council on Pain Management 2003 - 2009 Associate Professor Promotions Committee Johns Hopkins Hospital 2005 - 2009 Medical School Council Johns Hopkins University