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PowerPoint® Lecture Slides prepared by Barbara Heard, Atlantic Cape Community Ninth Edition College Human Anatomy & Physiology CHAPTER © Annie Leibovitz/Contact Press Images 4 © 2013 Pearson Education, Inc. Four Types of Tissue 1. Epithelial tissue 2. Connective tissue 3. Muscle tissue 4. Neural tissue 2 © 2012 Pearson Education, Inc. Epithelial Charact. Apical surface -cell junctions -Polarity -Attachment -Avascularity Basal © 2012 Pearson Education, Inc. 3 Epithelial Tissue • Functions 1. Physical Protection 2. Control Permeability 3. Sensation 4. Secretions 4 © 2012 Pearson Education, Inc. Epithelial Tissue • Epithelial cells can serve as barriers, so they need to be connected well. • How does this happen? • Anchor to base • Cell junctions 5 © 2012 Pearson Education, Inc. Epithelial Tissue • Anchor to base: • Basement Membrane (2 parts) • Clear layer (lamina lucida) • close to epithelium • glycoproteins • Dense layer (lamina densa) • collagen 6 © 2012 Pearson Education, Inc. Also cell-to-cell attachment: Tight junction Between two plasma membranes Containment of water/solutes -forms Lumen © 2012 Pearson Education, Inc. 7 Ion movement Channel proteins connect two sides Fast mvt. Gap junctions © 2012 Pearson Education, Inc. 8 Spot Desmosomes -Tie cells together -Allow bending and twisting Hemidesmosomes -Attach cells to the basal lamina Spot desmosome Hemidesmosomes © 2012 Pearson Education, Inc. 9 Epithelial Tissue • Epithelials are ‘used’ a lot! • Need Maintenance and Repair • replaced by division of germinative cells (stem cells) • Near basement membrane • There are several classes of Epithelial cells: 10 © 2012 Pearson Education, Inc. 11 © 2012 Pearson Education, Inc. 12 © 2012 Pearson Education, Inc. Simple Squamous Epithelium Friction reduction Absorption Secretion Cytoplasm Nucleus Connective tissue LM × 238 13 © 2012 Pearson Education, Inc. Keratin for strength water resistance Stratified Squamous Epithelium Squamous superficial cells Stem cells Basement membrane Connective tissue LM × 310 14 © 2012 Pearson Education, Inc. Secretion absorption Simple Cuboidal Epithelium Connective tissue Nucleus Cuboidal cells Basement membrane LM × 650 15 © 2012 Pearson Education, Inc. Sweat ducts mammary ducts Stratified Cuboidal Epithelium Lumen of duct Stratified cuboidal cells Basement membrane Nuclei Connective tissue LM × 500 16 © 2012 Pearson Education, Inc. Transitional Epithelium stretching recoiling Epithelium (relaxed) Basement membrane Empty bladder Connective tissue and smooth muscle layers LM × 400 Epithelium (stretched) Full bladder Basement membrane Connective tissue and smooth muscle layers LM × 400 LM × 400 17 © 2012 Pearson Education, Inc. Absorption secretion Simple Columnar Epithelium Microvilli Cytoplasm Nucleus Basement membrane Loose connective tissue LM × 350 18 © 2012 Pearson Education, Inc. Protection Movement Pseudostratified Ciliated Columnar Epithelium Cilia Cytoplasm Nuclei Basement membrane Loose connective tissue LM × 350 19 © 2012 Pearson Education, Inc. Lining of ducts Stratified Columnar Epithelium Lumen Loose connective tissue Deeper basal cells Superficial columnar cells Lumen Cytoplasm Nuclei Basement membrane LM × 175 20 © 2012 Pearson Education, Inc. Classification of Epithelia • Epithelia can make up glands: • Endocrine glands • Release hormones • Into interstitial fluid • No ducts • Exocrine glands • Produce secretions • Onto epithelial surfaces • Through ducts © 2012 Pearson Education, Inc. 21 Classification of Epithelia • Epithelia can secrete contents in three ways: 1. Merocrine secretion 2. Apocrine secretion 3. Holocrine secretion Think damage levels to cell 22 © 2012 Pearson Education, Inc. Salivary gland Merocrine – no damage 23 © 2012 Pearson Education, Inc. Mammary gland Breaks down Apocrine – some damage 24 © 2012 Pearson Education, Inc. Hair Sebaceous gland Hair follicle Stem cell Holocrine – total damage 25 © 2012 Pearson Education, Inc. Classification of Epithelia • Glandular Epithelia • Unicellular glands • Goblet cells are the only unicellular exocrine glands • in intestinal lining • Mucin 26 © 2012 Pearson Education, Inc. Classification of Epithelia • Multicellular glands • -Know Fig. 4.5– Structural Class. Exocrine Glands 27 © 2012 Pearson Education, Inc. Connective Tissues 28 © 2012 Pearson Education, Inc. Reticular fibers Strong & Flex -many directions Elastic fibers Stretchy Collagen fibers Strong & Flex -one direction Fibroblast -most common -make collagen Adipocytes (fat cells) Ground substance -filler -Cementing Mesenchymal cell -Stem cells 29 © 2012 Pearson Education, Inc. Connective Tissues 30 © 2012 Pearson Education, Inc. Loose Connective Tissues Adipose Tissue LOCATIONS: Deep to the skin, especially at sides, buttocks, breasts; padding around eyes and kidneys FUNCTIONS: Provides padding and cushions shocks; insulates (reduces heat loss); stores energy Adipocytes (white adipose cells) Adipose tissue LM × 300 31 © 2012 Pearson Education, Inc. Loose Connective Tissues Reticular Tissue LOCATIONS: Liver, kidney, spleen, lymph nodes, and bone marrow FUNCTIONS: Provides supporting framework Reticular fibers Reticular tissue from liver Reticular Tissue LM × 375 32 © 2012 Pearson Education, Inc. Connective Tissues 33 © 2012 Pearson Education, Inc. Connective Tissue Dense Regular Dense Irregular Elastic • Dense Regular Connective Tissue • parallel collagen fibers • Tendons attach muscles to bones • Ligaments connect bone to bone and stabilize organs • Aponeuroses attach in sheets to large, flat muscles 34 © 2012 Pearson Education, Inc. Dense Regular Dense Irregular Elastic Dense Regular Connective Tissue Collagen fibers Fibroblast nuclei LM × 440 35 © 2012 Pearson Education, Inc. Connective Tissue Dense Regular Dense Irregular Elastic • Dense Irregular Connective Tissue • networks of collagen fibers • Layered in skin • periosteum 36 © 2012 Pearson Education, Inc. Dense Regular Dense Irregular Elastic Dense Irregular Connective Tissue Collagen fiber bundles LM × 111 37 © 2012 Pearson Education, Inc. Connective Tissue Dense Regular Dense Irregular Elastic • Elastic Tissue • Made of elastic fibers • elastic ligaments of spinal vertebrae • arteries 38 © 2012 Pearson Education, Inc. Dense Regular Dense Irregular Elastic Elastic Tissue Elastic fibers Fibroblast nuclei LM × 887 39 © 2012 Pearson Education, Inc. Connective Tissues 40 © 2012 Pearson Education, Inc. Red blood cells Erythrocytes ¯ ¯ 41 © 2012 Pearson Education, Inc. White blood cells First Combatant, pus Leukocytes ¯ ¯ In lymph Neutrophil inflamatory response , heparin Combat Eosinophil Monocytes Lymphocytes Basophil Phagocytes & inflamators move fast, produce macrophages 42 © 2012 Pearson Education, Inc. Platelets Fragments Clotting 43 © 2012 Pearson Education, Inc. Connective Tissue • Fluid Elements of Connective Tissues • Extracellular • Plasma • Interstitial fluid • Lymph 44 © 2012 Pearson Education, Inc. Connective Tissue • Lymph • Extracellular fluid • Monitored by immune system • Transported by lymphatic system • Returned to venous system 45 © 2012 Pearson Education, Inc. Connective Tissues 46 © 2012 Pearson Education, Inc. Supporting Connective Tissues • Cartilage • Matrix • collagen, ground substance, elastin • Chondrocytes (cartilage cells) • lacunae (chambers) • No blood vessels 47 © 2012 Pearson Education, Inc. Supporting Connective Tissues • 3 Types of Cartilage 48 © 2012 Pearson Education, Inc. stiff, flexible friction reduction Hyaline Cartilage Chondrocytes in lacunae Matrix LM × 500 49 © 2012 Pearson Education, Inc. Support w/distortion Elastic Cartilage Chondrocyte in lacuna Elastic fibers in matrix LM × 358 50 © 2012 Pearson Education, Inc. Limit movement Fibrocartilage Chondrocytes in lacunae Fibrous matrix LM × 400 51 © 2012 Pearson Education, Inc. Supporting Connective Tissues • Bone or Osseous Tissue • Strong • Resists shattering • Osteocytes • cells • Periosteum • Covers bone surfaces (fibrous and cellular layers) 52 © 2012 Pearson Education, Inc. Canaliculi Osteocytes in lacunae Fibrous layer Periosteum Cellular layer Matrix Osteon Central canal Blood vessels Osteon LM × 375 53 © 2012 Pearson Education, Inc. long, thin no division Skeletal Muscle Tissue Nuclei Muscle fiber Striations LM × 180 54 © 2012 Pearson Education, Inc. Cardiocytes Branched Cardiac Muscle Tissue Nucleus Cardiac muscle cells Intercalated discs Striations LM × 450 55 © 2012 Pearson Education, Inc. small devide Smooth Muscle Tissue Nucleus Smooth muscle cell LM × 235 56 © 2012 Pearson Education, Inc. NEURONS NEUROGLIA (supporting cells) Dendrites Axon Nucleus Contact with other cells Cell body © 2012 Pearson Education, Inc. 57