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C. DAVID MINTZ, MD, PhD
ACADEMIC POSITIONS
Assistant Professor of Anesthesiology, Johns Hopkins University, 8/2013Instructor of Anesthesiology, Columbia University, 5/2012-7/2013
EDUCATION
Columbia University Medical Center
T32 Anesthesia Research Fellow, 7/2011-5/2012
Chief Resident in Anesthesiology 7/2010-7/2011
Anesthesiology Residency, 7/2008-7/2011
The Mount Sinai School of Medicine, New York, NY
Internal Medicine Internship, 7/2007-7/2008
MD, 5/2007
PhD in Biological Sciences, 9/2005
MS in Biological Sciences, 9/2003
Brown University, Providence, RI
BSc with concentration in Neuroscience, 5/1999
FELLOWSHIPS, AWARDS, AND HONORS
First Prize, Resident Research Contest, PGA/NYSSA, 2012
First Prize, Resident Research Contest, American Society of Anesthesiologists, 2012
Best of Abstracts: Basic Science, American Society of Anesthesiologists, 2012
First Prize, Basic Science, Columbia Anesthesiology Academic Evening, 2012
Resident Travel Award, Association of University Anesthesiologists, 2012
Apgar Research Scholarship, 2008-2012
First Prize, Basic Science, Columbia Anesthesiology Academic Evening, 2011
Alpha Omega Alpha, Lambda Chapter, elected 2006
Invited talk, Mount Sinai Medical Student Research Day, 2005
Honorable Mention, Mount Sinai Medical Student Research Day, 2003
Glenn Biology of Aging Fellowship, American Federation of Aging Research, 2002
Magna Cum Laude, Brown University, 1999
Neuroscience Departmental Honors, Brown University, 1999
Award for Excellence in Teaching, Dept. of Neuroscience, Brown University, 1999
Undergraduate Teaching and Research Award, Brown University, 1998
Summer Scholar, American Heart Association, 1995
GRANT SUPPORT
NIH Mentored Clinical Scientist Award, “The effects of anesthetics on brain
development”, NIGMS 1K08GM104329-01, 2/2013-2/2017.
Columbia Anesthesiology RAP Research Grant, 2011-2012
T32 Research Fellowship, NIH-NIGMS 5T32GM008464-19, 2011-2012
National Research Service Award, NIH-NINDS 5F30NS046142, 2003-2006
Seed Grant, American Medical Association Foundation, 2003
Medical Scientist Training Program, NIH-NIGMS 5T32GM7280-23, 1999-2002
PUBLICATIONS
Mintz CD*, Friedman A. Case Report: Masseter spasm on induction in a patient with
scleroderma. In preparation, target journal Anesthesia and Analgesia.
Mintz CD*, Barrett KMS, Smith SC, Benson DL, Harrison NL. (2013) Anesthetics
interfere with axon guidance in developing mouse neocortical neurons via a
GABAA receptor mechanism. Anesthesiology, 118(4):825-33
Mintz CD, Wagener M, Loepke AW. (2012) Preclinical Research into the effects of
anesthetics on the developing brain—promises and pitfalls. J Neurosurg
Anesthesiol, 24(4):362-367.
Mintz CD*, Smith SC, Barrett KMS, Benson DL. (2012) Anesthetics interfere with the
polarization of developing cortical neurons. J Neurosurg Anesthesiol, 24(4):368375.
Mintz, CD*. (2012) Book Review: Anesthetic Pharmacology: Basic Principles and
Clinical Practice, 2nd Edition. Anesthesiology, 117(4):926-927.
Hoffman EJ, Mintz CD‡, Wang S, McNickle DG, Salton SR, Benson DL. (2008) Effects
of ethanol on axon outgrowth and branching in developing rat cortical neurons.
Neuroscience. 157(3):556-65.
Mintz CD, Carcea I, McNickle DG, Dickson TC, Ge Y, Salton SR, Benson DL. (2008) ERM
proteins regulate growth cone responses to Sema3A. J Comp Neurol 510(4):351-66.
Mintz CD, Anderson TR, Bekirov IH, Benson DL (2006) Neuronal differentiation: from axons to
synapses, Chapter in Brain Development: Normal Processes and the Effects of Alcohol
and Nicotine, Ed. by MW Miller, Oxford University Press.
Mintz CD, Dickson TC, Gripp ML, Benson (2003) ERMs colocalize transiently with L1 during
neocortical axon outgrowth. J Comp Neurol 464(4):438-48.
Dickson TC, Mintz CD, Benson DL, Salton SR. (2002) Functional binding interaction identified
between the axonal CAM L1 and members of the ERM family. J Cell Biol 157(7):110512.
Nash MS, Mintz CD, Montalvo BM, Jacobs PL (2000) A randomized blinded comparison of two
methods used for venous antistasis in tetraplegia. J Spinal Cord Inj Med 23:221-227.
Jacobs PL, Nash MS, Mintz CD (1999) Assessment of fractional expired gases and air flow by
an ambulatory metabolic analyzer. JEPonline 2:20-28.
*Indicates corresponding author, ‡Indicates equally contributing co-first author
INVITED TALKS
Anesthetics interfere with axon guidance via a GABAA receptor mechanism, Resident Research
Contest Oral Presentation, PostGraduate Assembly in Anesthesiology, December 2012,
New York, NY.
Anesthetics and Axon Development, Best of Basic Science, American Society of
Anesthesiologists, October 2012, Washington, DC.
Anesthetics and Brain Development, Department of Anesthesiology, Duke University, September
2012, Durham, NC.
Anesthetics and Axon Development, Association of University Anesthesiologists Meeting, May
2012, Cleveland, OH.
Anesthetics and Axon Development. Academic Evening, Department of Anesthesiology,
Columbia University, May 2012, New York, NY.
Toxicity of Anesthetics in Developing Neurons. Department of Anesthesiology, University of
Miami, December 2011, Miami, FL.
Toxicity of Anesthetics in Developing Neurons. Research in Progress Seminar, Department of
Anesthesiology and Critical Care, University of Pennsylvania, November 2011,
Philadelphia, PA.
Anesthetics, GABA, and Axon Guidance. Academic Evening, Department of Anesthesiology,
Columbia University, June 2011, New York, NY.
Inhalational Anesthetics and neuron development. Mechanisms of Anesthesia Conference,
Neurotoxicity Workshop, June 2010, Toronto, Canada.
SELECTED POSTER PRESENTATIONS
Anesthetic agents interfere with the axonal growth cone response to Semaphorin 3A. Society for
Neuroscience Meeting, November 2011, Washington D.C.
Anesthetic agents interfere with the axonal growth cone response to Semaphorin 3A. American
Society for Anesthesiology, October 2011, Chicago, IL.
Effects of Isoflurane on Neuron Development, Association of University Anesthesiologists
Meeting, April 2010, Denver, CO.
RESEARCH TRAINING
Department of Anesthesiology, Columbia University Medical Center
T32 Basic Science Fellow in the Lab of Neil L. Harrison, PhD, 2011-2012
Toxicity of anesthetics in neuron development
Fishberg Department of Neuroscience, Mount Sinai Hospital
Graduate student and Postdoctoral Researcher, lab of Deanna L. Benson, PhD, 2001-8
Axon guidance, fetal alcohol syndrome, and synapse development
Department of Neuroscience, Brown University
Undergraduate student, lab of Michael A. Paradiso, PhD, 1996-9
Neurophysiology of primary visual cortex
Miami Project to Cure Paralysis, University of Miami
Research assistant, lab of Mark S. Nash, PhD, 1995-7
Deep vein thrombosis prophylaxis in spinal cord injured patients
CLINICAL CREDENTIALS
New York State Medical License
Board Eligible in Anesthesiology, 7/1/2011
Passed Anesthesiology Written Boards (Score 301), 7/2011, Oral exam 4/19/13
TEACHING
Adjunct Assistant Professor of Biology, Stern College, 2004-5
Teaching Assistant for Brain and Behavior Course, Mount Sinai, 2002-5
Teaching Assistant for Physiology Course, Mount Sinai, 2002-3
Co-director and instructor, CPR certification program, Mount Sinai, 2003-7
Teaching Assistant, Developmental Neuroscience, Brown University, 1998-9
Teaching Assistant, Introductory Neuroscience, Brown University, 1997-8
Teaching Assistant, Introductory Physiology, Brown University, 1998