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CURRICULUM VITAE FOR ACADEMIC PROMOTION The Johns Hopkins University School of Medicine Charles W. Hogue, Jr., MD 11/13/2007 DEMOGRAPHIC INFORMATION: Current Appointments: 2005-Present Visiting Associate Professor, Division of Cardiac Anesthesia, ACCM The Johns Hopkins University School of Medicine, Baltimore, Maryland Personal Data: Business Address Telephone Fax: E-mail: Department of Anesthesiology & Critical Care Medicine The Johns Hopkins Hospital - Tower 711 600 North Wolfe Street Baltimore, Maryland 21287-8711 410/614-1516 410/955-0994 [email protected] Education and Training: 1982 BS, Biology (Magna Cum Laude) Southern Illinois University, Edwardsville, IL 1986 MD, University of Illinois, Chicago, IL (Magna Cum Laude) 1986-1987 Internship, Department of Internal Medicine Washington University School of Medicine Jewish Hospital of St. Louis, MO 1987-1990 Residency, Department of Anesthesiology Harvard Medical School, Massachusetts General Hospital, Boston, MA 1987-1990 Clinical Fellow, Harvard Medical School, Boston, MA 1987-1990 Research Fellow, Shriners Burns Institute, Boston, MA Professional Experience: 1990-1991 Instructor, Dept of Anesthesiology, Harvard Medical School, Boston, MA 1990-1993 Instructor, Dept of Anesthesiology, Washington University School of Medicine, St. Louis, MO 1993-1998 Assistant Professor, Dept of Anesthesiology, Washington University School of Medicine, St. Louis, MO Charles W. Hogue, Jr., MD Curriculum Vitae 1998-2004 1998-2005 Chief, Division of Cardiothoracic Anesthesia, Dept of Anesthesiology Washington University School of Medicine, St. Louis, MO Associate Professor, Dept of Anesthesiology, Washington University School of Medicine, St. Louis, MO 2004-2005 Sabbatical. Time divided between work on grants, manuscripts, and clinical time at Papworth Hospital, Cambridge, England Dec 2005- Associate Professor, Department of Anesthesiology & Critical Care Medicine, Johns Hopkins University Medical School, Baltimore, MD RESEARCH ACTIVITIES: 1. Hogue CW, Itani MS, Martyn JAJ: Resistance to d-tubocurarine in lower motor neuron injury is related to increased acetylcholine receptors at the neuromuscular junction. Anesthesiology 1990;73:703-709 2. Hogue CW, Ward J, Itani MS, Martyn JAJ: Tolerance and upregulation of acetylcholine receptors follow chronic infusion of d-tubocurarine. J Appl Physiol 1992;72:1326-1331 3. Hogue CW, Peeress D, Vacanti CA, Alston TA: Potential toxicity from prolonged anesthesia: A case report of a thirty-hour anesthetic. J Clin Anesth 1990;2:183-187 4. Hogue CW, Martyn JAJ, Baker TR, Vourus P: Recovery of Pancuronium from peritoneal dialysate in a severely burned child. Anesth Analg 1991;73:83-86 5. Raines DE, Hogue CW, Wickens C, Welch J, Risk SC: Artifactual hypertension due to transducer cable malfunction. Anesthesiology 1991;74:1149-1151 6. Hogue CW, Platin M, Barzilai B, Kaiser LR: Intraoperative use of transesophageal echocardiography with pulsed-wave Doppler evaluation of ventricular filling dynamics during peri-cardiotomy. Anesthesiology 1991;75:701-704 7. Hogue CW, Barzilai B, Forstot R, Shuman TA, Cox JL: Intraoperative echocardiographic diagnosis of previously unrecognized Cor Triatriatum. Ann Thorac Surg 1992;54:562-563 8. Hand DE, Lappas DG, Hogue CW, Cox JL: Perioperative transesophageal doppler echocardiographic verification of atrial transport function following the maze procedure for atrial fibrillation. Surg Forum 1992;43:267-268 9. Hogue CW, Pulley DD, Lappas DG: Anesthetic-induced myocardial ischemia: the isoflurane-coronary steal controversy. Coronary Art Dis 1993;4:413-419 10. Hogue CW, Herbst TJ, Pond C, Apostolidou I, Lappas DG: Perioperative myocardial ischemia: its relation to anatomic pattern of coronary artery stenosis. Anesthesiology 1993;79:514-524 2 Charles W. Hogue, Jr., MD Curriculum Vitae 11. Hogue CW: Effectiveness of low levels of nonventilated lung continuous positive airway pressure in improving arterial oxygenation during one-lung ventilation. Anesth Analg 1994;79:364-367 12. Hogue CW, Rosenbloom MR, McCawley C, Lappas DG: Comparison of cardiac output measurement by continuous thermodilution with electromagnetometry in adult cardiac surgical patients. J Cardiothorac Vasc Anesth 1994;8:631-635 13. Hogue CW, Stein PK, Apostolidou I, Lappas DG, Kleiger RE: Alterations in temporal patterns of heart rate variability after coronary artery surgery. Anesthesiology 1994;81: 1356-1364 14. Despotis GJ, Joist JH, Hogue CW, Alsoufiev A, Kater K, Goodnough LT,Santoro SA, Sptiznagel E, Rosenblum M, Lappas DG: The impact of heparin concentration and activated clotting time monitoring on blood conservation: A prospective, randomized evaluation in patients undergoing cardiac operations. J Thorac Cardiovasc Surg 1995; 110:46-54 15. Hogue CW, Lappas GD, Creswell LL, Ferguson TB, Sample M, Pugh D, Balfe D, Cox J, Lappas DG: Swallowing dysfunction after cardiac surgery: associated adverse outcomes and risk factors including intraoperative transesophageal echocardiography. J Thorac Cardiovasc Surg 1995;110:517-522 16. Despotis GJ, Alsoufiev A, Hogue CW, Zoys T, Goodnough LT, Santoro SA, Kater KM, Barnes P, Lappas DG. Comparison of CBC results from a new, on-site hemocytometer to a laboratory-based hemocytometer. Crit Care Med 1996;24:1163-1167 17. Despotis GJ, Hogue CW, Santoro SA, Joist JH, Barnes PW, Lappas DG: Effect of heparin on whole blood partial thromboplastin time using a portable, whole blood coagulation monitor. Crit Care Med 1995;23:1674-79 18. Hogue CW, Davila-Roman VG, Stein PK, Feinberg M, Lappas DG, Perez JE: Alterations in heart rate variability in patients undergoing dobutamine stress echocardiography, including those who develop neurocardiogenic hypotension. Am Heart J 1995;130:1203-9 19. Goodnough LT, Despotis GJ, Hogue CW, Ferguson TB: On the need for improved transfusion indicators in cardiac surgery. Ann Thorac Surg 1995;60:473-80 20. Despotis GJ, Filos KS, Zoys TN, Hogue CW, Spitznagel E, Lappas DG: Factors associated with excessive postoperative blood loss and hemostatic transfusion requirements: a multivariate analysis in cardiac surgical patients. Anesth Analg 1996;82:13-21 21. Hogue CW, Davila-Roman VG, Pond C, Hauptmann E, Braby D, Lappas DG: Hemodynamic improvements versus the risk of myocardial ischemia: transesophageal atrial pacing in anesthetized patients with coronary artery disease. Anesthesiology 1996; 85:69-76 22. Hogue CW, Bowdle TA, O’Leary C, Duncalf D, Miguel R, Pitts M, Streisand J, Kirvassilis, Jamerson B, McNeal S, Batenhorst R: Multicenter evaluation of the safety and efficacy of total intravenous anesthesia with remifentanil and propofol for elective inpatient surgery. Anesth Analg 1996;83:279-85 3 Charles W. Hogue, Jr., MD Curriculum Vitae 23. Bowdle TA, Camporesi EM, Maysick L, Hogue CW, Miguel RV, Pitts M, Streisand JB: A multicenter evaluation of remifentanil for early postoperative analgesia. Anesth Analg 1996;83:1292-7 24. Despotis GJ, Joist JH, Hogue CW Jr, Alsoufiev A, Joiner-Maier D, Santoro SA, Spitznagel E, Weitz J, Goodnough LR: More effective suppression of hemostatic system activation in patients undergoing cardiac surgery by heparin dosing based on heparin blood concentrations rather than ACT. Thrombo Hemost 1996;76:902-908 25. Hogue CW Jr, Davila-Roman VG: Detection of myocardial ischemia by transesophageal echocardiography determined changes in left ventricular area in patients undergoing coronary artery bypass surgery. J Clin Anesth 1997;9:388-393 26. Hogue CW Jr, Domitrovich PP, Stein PK, Despotis GD, Re L, Schuessler RB, Kleiger RE, Rottman JN. RR interval dynamics prior to atrial fibrillation in patients after coronary artery surgery. Circulation 1998;98:429-434 27. Hogue CW Jr, Goodnough LT, Monk TG. Perioperative myocardial ischemic episodes are related to hematocrit level in patients undergoing radical prostatectomy. Transfusion 1998;38:924-931 28. Noda S, Buckmaster MJ, Hogue CW Jr, Rubin BG, Sundt TM III. Intraabdominal hemorrhage during combined coronary artery bypass and carotid endarterectomy. Ann Thorac Surg 1998;66:557-558 29. Hogue CW Jr. Con: Pharmacologic prophylaxis should be used in all patients having cardiac surgery. J Cardiothor Vasc Anesthesia 1999;13:101-104 30. Hogue CW Jr, Barzilai B, Davila-Roman VG. Stroke reduction: Diagnosis and management of the atherosclerotic ascending aorta during cardiac surgery. Sem Cardiothor Vasc Anesth 1999;3:1-9. 31. Hogue CW Jr, Murphy SF, Schechtman KB, Davila-Roman. Risk factors for early or delayed stroke after cardiac surgery. Circulation 1999;100:642-47 32. Apostolidou IA, Despotis GJ, Hogue CW Jr, Skubas NJ, McCawley CA, Hauptmann EL, Lappas DG. Anti-ischemic effects of nicardipine and nitroglycerin following coronary artery bypass surgery. Ann Thorac Surg 1999;67:417-22 33. Apostolidou I, Skubas NJ, Bakola A, Hogue CW Jr, Despotis GJ, McCawley CA, Lappas DG. Effects of nicardipine and nitroglycerin on perioperative myocardial ischemia in patients undergoing coronary artery bypass surgery. Sem Thorac Cardiovasc Surg 1999;11:77-83. 34. Hogue CW Jr, Davila-Roman VG, Sundt TM III, Barner H, Goldberg M. Neurologic complications of cardiac surgery: emerging paradigms in prevention and treatment. Seminars in Cardiothoracic Surgery 1999;11:105-115 35. Hogue CW Jr, Stamos T, Winter KJ, Moulton M, Krucylak PE, Cooper JD. Acute myocardial infarction during lung volume reduction surgery. Anesth Analg 1999;88:332-4 4 Charles W. Hogue, Jr., MD Curriculum Vitae 36. Despotis GJ, Hogue CW Jr. Pathophysiology, prevention and treatment of bleeding after cardiac surgery: A primer for cardiologist and an update for the cardiothoracic team. Am J Cardiol 1999;83:15B-30B 37. Hogue CW Jr., Hyder ML. Atrial fibrillation after cardiac surgery: risks, mechanisms and prophylaxis. Ann Thorac Surg 2000;69:300-6 38. Hogue CW Jr., Filos KS, Schuessler RB, Sundt TM III. Sinus nodal function and risk for atrial fibrillation risk after coronary artery bypass graft surgery. Anesthesiology 2000;92: 1286-92 39. Cheung AT, Hogue CW Jr. Dysphagia after cardiac surgery: How safe is TEE? Ann Thorac Surg 2000;69:486-490 40. Hogue CW Jr, Barzilai B, Pieper KS, Coombs LP, DeLong ER, Kouchoukos NT, DavilaRoman VG. Sex differences in neurologic outcomes and mortality after cardiac surgery: A Society of Thoracic Surgery National Database Report. Circulation 2001;103:2133-7 41. Howie M, Cheng D, Newman MF, Pierce ET, Hogue CW , Hillel Z, Bowdle TA, Bukenya D. A randomized double-blind multicenter comparison of remifentanil versus fentanyl with isoflurane/propofol for early extubation after CABG surgery. Anesth Analg 2001;92:108493. 42. Cheng DC, Newman MF, Duke P, Wong DT, Finegan B, Howie, Fitch J, Bowdle AT, Hogue CW, Hillel Z, Pierce E, Bukenya D. The efficacy and resource utilization of remifentanil and fentanyl in fast-track coronary artery bypass graft surgery: a prospective randomized, double-blinded controlled, multi-center trial. Anesth Analg 2001;92:10941102. 43. Heerdt PM, Blessios GA, Beach ML, Hogue CW. Flow dependency of error in thermodilution measurement of cardiac output during acute tricuspid regurgitation. J Cardiothorac Vasc Anesth 2001;15:183-7 44. Skubas N, Barzilai B, Hogue CW Jr. Atrial fibrillation after CABG surgery is unrelated to cardiac abnormalities detected by transesophageal echocardiography. Anesth Analg 2001;93:14-9 45. Despotis GJ, Hogue CW, Saleem R, Bigham M, Skubas N, Apostolidou I, Qayum A, Joist JH. The relationship between hirudin and activated clotting time: Implications for patients with heparin-induced thrombocytopenia undergoing cardiac surgery. Anesth Analg 2001; 93:28-32 46. Apostolidou IA, Skubas NJ, Despotis GJ, Kallinteri E, Hogue CW, Lappas DG, Barner HB. Occurrence of myocardial ischemia immediately after coronary revascularization using radial arterial conduits. J Cardiothorac Vasc Anesth 2001;15:433-38 47. Hogue CW Jr, Sundt TM III, Barzilai B, Schecthman K, Davila-Roman VG. Cardiac and neurologic complications identify risk for mortality for both men and women undergoing coronary artery bypass graft surgery. Anesthesiology 2001;95:1074-8 5 Charles W. Hogue, Jr., MD Curriculum Vitae 48. Despotis GJ, Avidan MS, Hogue CW Jr. Mechanisms and attenuation of hemostatic activation during extracorporeal circulation. Ann Thorac Surg 2001;72:S1821-31 49. Davila-Roman VG, Hogue CW Jr. Safety and effficacy of intraarterial thrombolysis for perioperative stroke after cardiac operation. Editorial. Ann Thorac Surg 2001;72:1938-9 50. Hill LL, Kattapuram M, Hogue CW Jr. Management of Atrial fibrillation after cardiac surgery. Part I: Pathophysiology and risk. J Cardiothorac Vasc Anesth 2002;16:483-494 51. Hogue CW Jr, Talke P, Stein PK, Richardson C, Domitrovich PP, Sessler DI. Autonomic nervous system responses during sedative infusions of dexmedetomidine. Anesthesiology 2002;97:592-8 52. Hill LL, Kattapuram M, Hogue CW Jr. Management of atrial fibrillation after cardiac surgery. Part II: Prevention and treatment J Cardiothorac Vasc Anesth 2002;16:626-37 53. Rasmussen GL, Steckner K, Hogue C, Kuss M, Torri S, Hubbard RC. Intravenous parecoxib sodium for acute pain after orthopedic knee surgery. Am J Orthopedics 2002; 336-43 54. Hogue CW Jr, De Wet C, Schechtman KB. The Importance of prior stroke for the adjusted risk of neurologic injury after cardiac surgery for women and men. Anesthesiology 2003;98:823-9 55. Hogue CW Jr, Lillie R, Hershey T, Birge S, Nassief AM, Thomas B, Fredland KE. Gender influence on cognitive function after cardiac surgery. Ann Thorac Surg 2003;76:11191125 56. McMurry SA, Hogue CW Jr. Atrial fibrillation and cardiac surgery. Curr Opin Anaesthesiol 2004;17:63-70 57. Braun EB, Palin CA, Hogue CW. Vasopressin During Spinal Anesthesia in a Patient with Primary Pulmonary Hypertension Treated with Intravenous Epoprostenol. Anesth Analg, 2004;99:36-7 58. Amar D, Weiji S, Hogue CW Jr, Zhang H, Passman RS, Thomas B, Bach PB, Damiano R, Thaler HT. Clinical prediction rule for atrial fibrillation after coronary artery bypass grafting. J Am Coll Cardiol 2004;44:1248-53 59. Palin CA, Kailasam R, Hogue CW Jr. Atrial fibrillation after cardiac surgery: pathophysiology and treatment. Semin Cardiothorac Anesth 2004;8(3):175-83. 60. Kailasam R, Palin CA, Hogue CW Jr., Atrial fibrillation after cardiac surgery: an evidence based approach to prevention. Semin Cardiothorac Anesth 2005;9:77-85 61. McDonald SB, Renna M, Spitznagel EL, Avidan M, Hogue CW Jr, Moon MR, Barzilai B, Saleem R, McDonald JM, Despotis GJ. Preoperative use of enoxaprim increases the risk for postoperative bleeding and re-exploration in cardiac surgery patients. J Cardiothorac Vasc Anesth 2005;19:4-10 6 Charles W. Hogue, Jr., MD Curriculum Vitae 62. Hogue CW Jr, Creswell LL, Gutterman DD,Fleisher L. ACCP guidelines for the prevention and management of postoperative atrial fibrillation: Epidemiology, mechanisms, and risk. Chest 2005;128:9S-16S 63. Bradley D, Creswell LL, Hogue CW Jr, Epstein AE, Prystowsky EN, Daoud EG. ACCP guidelines for the prevention and management of postoperative atrial fibrillation: Pharmacological Prophylaxis. Chest 2005;128:39S-47S 64. Hogue CW Jr, Hershey T, Dixon D, Fucetola R, Nassief A, Freedland KE, Thomas B, Schechtman KB. Pre-existing cognitive impairment in women prior to cardiac surgery and its relation with C-reactive protein concentrations. Anesth Analg 2006;102:1602-8 65. Hogue CW Jr, Palin CA, Kailasam R, Lawton JS, Nassief, Dávila-Román VG, Thomas B, Damiano R. C-reactive protein levels and atrial fibrillation after cardiac surgery in women. Ann Thorac Surg 2006;82:97-102 66. Hogue CW Jr, Palin C, Arrowsmith JA. Management of cardiopulmonary bypass and neurologic complications: A critical appraisal of current practices. Anesth Analg 2006;103:21-37 67. Bennett-Guerrero E, Grocott HP, Levy JH, Stierer KA, Hogue CW, Cheung AT, Newman MF, Carter AA, Rossignol DP, Collard CD. A phase II double-blind placebo-controlled ascending dose study of eritoran (E5564), a lipid antagonist, in patients undergoing cardiac surgery with cardiopulmonary bypass. Anesth Analg 2007;104:378-83 68. Hogue CW, London MJ. Aprotinin use during cardiac surgery: a new or continuing controversy? Anesth Analg 2006;103:1067-70. 69. Hogue CW Jr, Freedland K, Hershey T, Fucetola R, Nassief A, Barzilai B, Thomas B, Birge S, Dixon D, Schechtman KB, Dávila-Román VG. Neurocognitive Outcomes are not Improved by 17-Estradiol in Postmenopausal Women Undergoing Cardiac Surgery. Stroke 2007;38:2048-54. 70. Hogue CW Jr, Selnes OA, McKhann G. Should all patients undergoing cardiac surgery have psychometric testing? A brain stress test. Anesth Analg 2007;104:1012-14. 71. Benjo A, Thompson RE, Fine D, Hogue CW, Alejo D, Kaw A, Gerstenblith G, Shah A, Berkowitz DE, Nyhan D. Pulse pressure is an age-independent predictor of stroke development following cardiac surgery. J Hyperten 2007;50:630-35. 72. Hogue CW Jr, Stearns J, Gottesman R. Cerebral injury after cardiac surgery. Critical Care Clin of North America (in press) 73. Hogue CW Jr, Hershey T, Dixon D, Fucetola R, Nassief A, Freedland KE, Thomas B, Schechtman KB, Freedland K. The impact of neurocognitive dysfunction on quality of life after cardiac surgery for postmenopausal women. Anesth Analg (in press) 74. Gottesman R, Hogue CW. Incidence, topography, predictors and long term survival following stroke in patients undergoing CABG surgery. (Editorial) Ann Thorac Surg 2008 (in press) 7 Charles W. Hogue, Jr., MD Curriculum Vitae 75. Grogan K, Stearns J, Hogue CW. Brain protection during cardiac surgery. Anesth Clin North America 2008 (in press) 76. Hogue CW Jr, Nassief A, Fucetola R, Hershey T, Barzilai B, Thomas B, Schechtman KB, Davila-Roman VG, Freeman B. Polymorphisms of inflammatory genes and neurologic outcomes after cardiac surgery in women. (manuscript in preparation). 77. Hogue CW Jr, Despotis G. Does perioperative estrogen replacement affect blood loss after cardiac surgery for postmenopausal women. (manuscript in preparation). Invited publications: 1. Hogue CW. Myocardial ischemia and infarction. In: Postoperative Critical Care of the Massachusetts General Hospital. Hoffman WJ, Wasnick JD (ed). Boston, MA, Little, Brown and Company, Second Edition, 1992, pp 141-154 2. Lappas DG, Hogue CW, Cain ME, Cox JL. Anesthesia for electrophysiological procedures. In: Cardiac Anesthesia, Kaplan JA (ed), Grune and Stratton, New York, 3rd edition, 1993, pp781-818 3. Cox JL, Boineau JP, Schuessler RB, Kater KM, Ferguson TB, Cain ME, Lindsay BD, Smith JM, Corr PB, Hogue CW, Lappas DG. Electrophysiologic basis, surgical development, and clinical results of the maze procedure for atrial flutter and atrial fibrillation. In: Advances in Cardiac Surgery. Karp RB (ed), Mosby, St. Louis, MO, Vol 6, 1995, pp 1-67 4. Hogue CW. Atrial septal defects, repair of. In: Essence of Anesthesia Practice, Roizen MF and Fleisher LA (ed), W.B. Saunders, Co, Philadelphia, PA, 1997, p 347 5. Hogue CW. Chagas Disease of the heart. In: Essence of Anesthesia Practice, Roizen MF and Fleisher LA (ed), W.B. Saunders Co, Philadelphia, PA, 1997, p75 6. Hogue CW. Commentary: Nishimura RA, Hayes DL, Holmes DR, Tajik AJ: Mechanism of hemodynamic improvement by dual-chamber pacing for severe left ventricular dysfunction: an acute Doppler and catheterization hemodynamic study. J Am Coll Cardiol 1995;25:281-8, In: The Cardiovasc & Thorac Journal Club Journal 1996;1:24-6 7. Hogue CW. Commentary: Valkama JO, Huikuri HV, Koistinen J, Yli-Mayry S, Airaksinen J, Myerburg RJ: Relation between heart rate variability and spontaneous and induced ventricular arrhythmias in patients with coronary artery disease. J Am Coll Cardiol 1995; 25:437-43. In: The Cardiovasc & Thorac Journal Club Journal 1996;1:28-32 8. Hogue CW. Commentary: Pires LA, Wagshal AB, Lancey R, Huang SK: Arrhythmias and conduction disturbances after coronary artery bypass graft surgery: epidemiology, management, and prognosis. Am Heart J 1995;129:799-808 In: The Cardiovasc & Thorac Journal Club Journal 1996;1:152-154 9. Hogue CW Jr. Supraventricular arrhythmias after cardiac surgery. In: Complications in Anesthesia. Atlee JL (ed). WB Saunders, Co, Philadelphia, PA 1998, pp 337-340 8 Charles W. Hogue, Jr., MD Curriculum Vitae 10. Stix M, Hogue CW Jr, Despotis GD. Bleeding after cardiopulmonary bypass. In: Complications in Anesthesia. Atlee JL (ed). WB Saunders, Co, Philadelphia, PA 1998, pp 299-302 11. Stix M, Hogue CW Jr, Despotis GD. Anticoagulation for cardiopulmonary bypass. In: Complications in Anesthesia. Atlee JL (ed). WB Saunders, Co, Philadelphia, PA 1998, pp 295-298 12. Skubas NJ, Hogue CW Jr, Cox JL, Lappas DG. Anesthesia for electrophysiologic procedures. In: Cardiac Anesthesia, Kaplan JA, Reich DL, Konstadt SN (ed), W.B. Saunders, Co, Philadelphia, PA, 1998, pp 861-899 13. Bigham M, Dickstein M, Hogue CW Jr. Anesthesia for heart and lung transplantation. In: Estafanous FG, Barash PG, Reves JG (ed), Cardiac Anesthesia, 2nd edition, Lippincott Williams & Wilkins, Philadelphia, PA, 2001, pp 637-662 14. Skubas N, Dickstein MD, Hogue CW Jr. Anesthesia for Heart and Lung Transplantation. Harvard Education Anesthesia Library. Bailin, M (Ed). Lippincott, Inc, Philadelphia, PA , Chapter 7, 2002 15. Iantchoulev SA, Hogue CW Jr. Chagas' disease. In: Essence of Anesthesia Practice. 2nd Edition, Roizen MF, Fleisher LA (ed). WB Saunders Co., Philadelphia, PA, 2002. 16. McDonald SB, Hogue CW Jr. Atrial septal defect, repair of. In: Essence of Anesthesia Practice. 2nd Edition, Roizen MF, Fleisher LA (ed). WB Saunders Co., Philadelphia, PA, 2002. 17. Gleva MJ, Hogue CW Jr. Anti-arrhythmic agents. In: Anesthetic Pharmacology: Physiologic Principles and Clinical Practice. Evers AS, Maze M (ed), 2003, pp 621-640. 18. Hogue CW Jr, Tuman KJ, Gravlee G. Cardiovascular Anesthesia: The Society of Cardiovascualr Anesthesiologist, its journal, and new opportunities. Anesth Analg 2004;98:1200 (editorial) 19. Andritsos MJ, Faddis M, Hogue CW Jr. Anesthesia for electrophysiologic procedures. In: Cardiac Anesthesia, 5th Edition, Kaplan JA, Reich DL, Konstadt SN (ed), W.B. Saunders, Co, Philadelphia, PA, 2006, pp355-381 20. Palin CA, Hogue CW Jr. Atrial and ventricular arrhythmia management. In: Perioperative Care in Cardiac Anesthesia and Surgery. Cheng D, David T (eds). Chapter 42, pp 359-367. 21. McMurry SA, Hogue CW Jr. ACLS for the Anesthesiologist. Current Reviews in Anesthesiology. 2004;25:136-42 22. Hogue CW Jr. (Book Review) Cardiopulmonary Resuscitation. Ornato JP, Perberdy MA (EDS), Humana Press, Totowa, NJ, Anes Analg 2005 23. Hogue CW. Perioperative Management of Cardiac Arrhythmias. 2007 Refresher Course Lecture. Annual meeting of the International Anesthesiology Research Association. Pp3842. 9 Charles W. Hogue, Jr., MD Curriculum Vitae 24. Stearns Joshua D, Hogue CW. Neurological Complications. In: Core Topics in Cardiac Anaesthesia. Ed: Mackay JH and Arrowsmith JE, Greenwich Medical Media, Limited, London, UK, 2006 (in press) Letters to the Editor: 1. Martyn JAJ, Hogue CW: Resistance Anesthesiology 1991;74:960-961 to d-tubocurarine following denervation. 2. Hogue CW: Isoflurane and outcome after coronary artery surgery. Anesth Analg 1991;72: 842 3. Hogue CW, Stein PK: Heart rate variability changes in association with ST segment depression during cesarean section under regional anesthesia. Anesth Analg 1994; 79:812-813 Movies: 1. Total intravenous anesthesia for thoracic surgical procedures with remifentanil: A new short-acting opioid. Glaxo, Research Triangle, NC Abstracts: 1. Hogue CW, Martyn JAJ: Lower motor neuron injury induces resistance to d-tubocurarine. Anesthesiology 1988,69:A501 2. Hogue CW, Itani MS, Martyn JAJ: Resistance to d-tubocurarine in lower motor neuron injury is related to increased acetylcholine receptors at the neuromuscular junction. Anesthesiology 1989;71:A1203 3. Hogue CW, Itani MS, Martyn JAJ: Continuous Infusion of d-tubocurarine induces tolerance and increases in nicotinic acetylcholine receptors. Anesthesiology 1990;73: A1273 4. Hogue CW, Herbst T, Pond C, Bowlin J, Lappas D: Perioperative myocardial ischemia in relation to anatomic characteristics of coronary arterial stenosis. Anesthesiology 1991; 75:A96 5. Hogue CW, Itani MS, Martyn JAJ: Elimination of metocurine by hemofiltration in patients undergoing cardiopulmonary bypass. Anesthesiology 1991;75:A801 6. Triantafillou AN, Heerdt PM, Herbst TJ, Hogue CW, Despotis GJ, Pond CG, Lappas DG: Intraoperative management of patients undergoing single lung transplantation for pulmonary hypertension. The 14th Ann Mtng Soc of Cardiovas Anesthes, p 286, 1992 7. Hogue CW, Shelton M, Pond C, Herbst T, Apostolidou I, Lappas DG: The relation between angiographic morphology of coronary artery stenosis and perioperative myocardial ischemic episodes. Anesthesiology 77:A68, 1992 10 Charles W. Hogue, Jr., MD Curriculum Vitae 8. Triantafillou AN, Heerdt PM, Hogue CW, Pond CG, Swarm R, Turner S, Lappas DG: Epidural vs intravenous morphine for postoperative pain management after lung transplantation. Anesthesiology 77:A858 9. Hogue CW, Lappas DG: Heart rate variability patterns in cardiac surgical patients and the influence of beta-adrenergic blocking drugs. The 15th Ann Mtg Soc Cardiovasc Anesthes, San Diego, CA, 1993 10. Triantafillou AN, Heerdt PM, Pond CG, Despotis G, Hogue CW, Forstot R, Cerza R, Lappas DG: Anesthetic management of patients for lung transplantation: the first 150 cases. The 15th Ann Mtng Soc Cardiovasc Anesthes, San Diego, CA, 1993 11. Hogue CW, Sample M, Pugh D, Ferguson TB, Creswell LL, Lappas DG: Swallowing disorders following cardiac surgery: risk factors and outcome. Anesthesiology 79:A311, 1993 12. Hogue CW, Cerza RF, Rosenbloom M, Lappas DG: Comparison of continual thermodilution cardiac output with electromagnetometry. Anesthesiology 79:A467, 1993 13. Despotis GJ, Zoys T, Hogue CW, Lappas DG, Lappas GD: Heparin dose is not independently associated with an increased incidence of bleeding in cardiac surgical patients. Anesthesiology 79:A91, 1993 14. Monk TG, Despotis GJ, Hogue CW, Lappas DG: Hemodynamic and echocardiographic alterations during laparoscopic surgery. Anesthesiology 79:A54, 1992 15. Hogue CW. Effective continuous positive airway pressure in thoracic surgical patients with the Mallinckrodt disposable system. The 16th Ann Mtg Soc Cardiovasc Anesthes, Montreal, Canada, p 303, 1994 16. Hogue CW, Kirvassilis GB, Ding Y, Martin K, Lappas DG: Recovery of heart rate variability is associated with other signs of sympathetic activation. Anesthesiology 1994; 81:A151 17. Karanikolas MS, Triantafillou AN, Pond CG, Despotis GJ, Cerza RF, Forstot R, Hogue CW, Apostolidou I, Kirvassilis GB, Lappas DG: Outcome of lung transplantation in relation to intra-operative crystalloid fluid administration. Anesthesiology 1994;81:A1464 18. Hogue CW, Davila VG, Pond C, Lappas DG: What is an optimal heart rate in anesthetized patients prior to coronary artery bypass surgery? Anesth Analg 1995;80: SCA104 19. Hogue CW, Lappas GD, Creswell LL, Ferguson TB, Sample M, Cox JL, Lappas DG. Risk factors and importance to clinical outcome of swallowing dysfunction after cardiac surgery. Anesth Analg 1995;80:SCA49 20. Karanikolas MS, Triantafillou AN, Pond CG, Hogue CW, Forstot R, Cerza R, Kirvassilis G, Apostilidou I: Lung transplantation. Before or after the operation? Anesth Analg 1995; 80:SCA30 11 Charles W. Hogue, Jr., MD Curriculum Vitae 21. Hogue CW, Camporesi E, Duncalf D, Miguel R, Pitts M, Streisand J, Batenhorst R, Jamerson B, McNeal S: Total intravenous anesthesia with remifentanil and propofol in patients undergoing elective inpatient surgery. Anesthesiology 83:A386,1995 22. Heerdt PM, Pleimann BE, Hogue CW: Flow-dependency of error in thermodilution cardiac output during tricuspid regurgitation in dogs. Anesthesiology 83:A615, 1995 23. Despotis GJ, Joist JH, Hogue CW, Alsoufiev A, Joiner-Maier D, Spitznagel E, Santoro SA, Goodnough LT: The effect of higher heparin concentrations on preservation of hemostasis in cardiac surgical patients. Anesthesiology 83:A91, 1995 24. Apostolidou I, Despotis GJ, McCawley C, Hogue CW, Hauptmann E, Lappas DG. Antiischemic effects of intravenous nicardipine and nitroglycerin following CABG surgery. Anesth Analg 1996;82:SCA43 25. Hogue CW Jr, Goodnough LT, Ding Y, Monk TG. Myocardial ischemic episodes in elderly patients having autologous blood procurement. Anesthesiology 1996;85:A50 26. Hogue CW Jr, Davila-Roman VG, Lappas DG, Pond C. Hauptmann E. Changes in left ventricular dimensions as an indicator of myocardial ischemia in patients undergoing cardiac surgery. Anesthesiology 1996;85:A76 27. Apostolidou I, Despotis GJ, Skubas N, Hogue CW Jr, Triantafillou AN, Lappas DG. Cost comparison of nicardipine and nitroglycerin infusion in cardiac surgery. Anesthesiology 1996;85:A114 28. Hogue CW Jr, Filos K, Schuessler R, Lappas DG, Sundt T, Ferguson TB. Sinus nodal function in patients with and without atrial fibrillation after coronary artery bypass surgery. Anesthesiology 1996;85:A152 29. Harris KM, Moon K, Davila-Roman VG, Perez JE, Hogue CW, Sundt TM, Barzilai B. Three-dimensional echocardiographic evaluation of mitral annulus morphology in patients with ischemic and nonischemic mitral regurgitation. Circulation 1996;94(Suppl I):I0655 30. Hogue CW Jr, Murphy S, Schechtman K, Davila-Roman VG. Predictors of late stroke occurring after initial recovery from cardiac surgery. Assn Univer Anesthes, Washington, DC, 18, 1997 31. Hogue CW Jr, Domitrovich PP, Stein PK, Schuessler R, Rottman JN. Altered heart rate dynamics prior to atrial fibrillation after coronary artery surgery. Anesth Analg 1997;84: SCA92 32. Hogue CW Jr, Murphy SF, Schechtman KB, Davila-Roman VG. Predictors of stroke occurring after initial uneventful recovery from cardiac surgery. Anesthesiology 1997;87: A121 33. Hogue CW Jr, Domitrovich PP, Stein PK, Despotis G, Rottman J. Atrial fibrillation risks after CABG is associated with altered heart rate dynamics. Anesthesiology 1997;87:A129 34. Hogue CW Jr, Sundt T, Barzilai B, Schechtman K, Dávila-Román VG. Modification of stroke risk after coronary artery bypass graft surgery using aggressive detection of 12 Charles W. Hogue, Jr., MD Curriculum Vitae atherosclerosis of the ascending aorta and carotid arteries. Assn Univ Anesthes Ann Mtg, San Francisco, CA, 1998 35. Hogue CW Jr, Filos K, Stein PK. Impaired sympathetic reflex responses and sinus nodal function after CABG surgery. Anesthesiology 1998;89:A249 36. Hogue CW Jr, Dávila-Román VG. Strategies to decrease stroke after CABG surgery. Anesthesiology 1998;89:A233 37. Hillel Z, Howie M, Hogue C, Haddow G, Fitch J, Bowdle A, Nielsen V, Bukenya D, et al. A multicenter trial comparing the safety and efficacy of remifentanil and fentanyl in elective CABG surgery patients. Anesth Analg 1999;88:SCA76 38. Hogue CW Jr, Sundt T, Schechtman K, Dávila-Román VG. Gender specific risk profiles for mortality after CABG surgery. Assn Univ Anesthes Ann Mtg, Pittsburgh, PA, 1999. 39. Hogue CW, Sundt T, Schechtman K, Dávila-Román VG. Gender specific risk profiles for mortality after CABG surgery. Anesthesiology 1999;91:A65 40. Hogue CW, Davila-Roman VG. Gender risk for stroke after cardiac surgery. Ann Mtg Soc Cardiovasc Anesth, Orlando, FL, 2000. Anesth Analg 2000;90:S 41. Hogue CW Jr, Skubas NJ. Atrial fibrillation after CABG surgery is unrelated to preexisting cardiac structural or functional abnormalities. Anesthesiology 2000;93:A218 42. Hogue CW, Sundt T, Schechtman K, Dávila-Román VG. Risk factors for stroke after cardiac surgery for women. Anesthesiology 2000;93:A250 43. Despotis GJ, Saleem R, Bigham M, Apostolidou I, Hogue CW. Point-of-care monitoring of hirudin anticoagulation with the ACT: Implications for patients with HIT undergoing cardiac surgery. Anesthesiology 2000;93:295 44. Hogue CW, Talke P, Sessler DI, Richardson CA. Autonomic responses to thermal stressors during dexmedetomidine versus placebo infusions in volunteers. Anesthesiology 2000;93:A158 45. Hill LL, Apostolidou I, Davila-Roman VG, Hogue CW Jr. Postmenopausal estrogen use and neurologic events after cardiac surgery. Anesth Analg 2001;92:SCA21 46. Apostolidou IA, Landenson JH, Lappas DG, Despotis GD, Chen JJ, Hogue CW, Davila VG. Does cardiac troponin I predict perioperative myocardial infarction in coronary artery bypass surgery: a comparison of techniques. Anesth Analg 2001;92:SCA49. 47. Cheung AT, Ebert TJ, Hogue CW, Ochroch EA. Respiratory actions of dexmedetomidine used for postoperative sedation in cardiac surgical patients. Anesth Analg 2001;92: SCA110 48. McDonald SB, Despotis G, Hogue CW, McDonald J, Moon M. Preoperative use of enoxaparin increases risk of postoperative bleeding and re-exploration in cardiac surgery patients. Amer Soc Anesthes Ann Mtg, 2001, A-200 13 Charles W. Hogue, Jr., MD Curriculum Vitae 49. Hogue CW Jr, Havlin R, Thomas B, Hershey T, Freedland K. Gender differences in patterns of cognitive dysfunction after cardiac surgery. Amer Soc Anesthes Ann Mtg, 2001, A-251 50. Amar D, Zhang H, Hogue CW, Shi W, Thaler H. Preoperative risk factors for post-CABG atrial fibrillation. Amer Soc Anesthes Ann Mtg, 2003, A-203 51. Hogue C, McMurry S, Muhlbaier L, Welke K, Ferguson T. Stroke risk after CABG surgery is not modified by the development of postoperative atrial fibrillation. Soc Cardiovas Anesthes Ann Mtg, 2004, SCA 17 52. Hogue CW Jr, Palin C, Kailsam R, Thomas B. Risk for atrial fibrillation after cardiac surgery is unrelated to baseline C-reactive protein concentrations in women. Ann Mtg Amer Soc Anesthes. 2004, 275 53. Hogue CW, Dixon D, Hershey T, Fucetola R, Nassief A, Schechtman K. Relation between C-reactive protein levels and pre-existing cognitive impairment in women before cardiac surgery. Soc Cardiovas Anesthes, Baltimore, MD, 2005 54. Hogue CW, Dixon D, Hershey T, Fucetola R, Nassief A, Schechtman K. C-reactive protein levels but not statin or aspirin use associated pre-existing cognitive impairment in women before cardiac surgery. Ann Mtg Eur Assn Cardiothor Anesthes, Montepellier, France, June 2, 2005 55. Hogue CW, Grogan K, Dixon D, Schechtman, Thomas B. 17β-Estradiol fails to provide neuroprotection during cardiac surgery in postmenopausal women. Annual Meeting of the American Society of Anesthesiologist, Anesthesiology Journal Symposium, October 17, 2006, Chicago, IL. 56. Hogue CW, Hershey T, Fucetola R, Schechtman K, Freedland K. Depression and neurocognitive dysfunction impact quality of life after cardiac surgery. Annual Meeting of the American Society of Anesthesiologist, October 16, 2007, San Francicso, CA A-1442. 57. Hogue CW, Benjo A, Berkowitz D, Nyhan D. Pulse pressure predicts stroke and acute renal dysfunction after cardiac surgery. Annual Meeting of the American Society of Anesthesiologist, October 16, 2007, San Francicso, CA A-1680. Research Support: 1. Effectiveness of a disposable, self-assembled CPAP device to improve oxygenation during one-lung ventilation in patients having thoracic surgery. $18,000, 1992 2. Evaluation of changes in heart rate variability in cardiac surgical patients in relation to susceptibility to postoperative atrial fibrillation. Equipment grant, Marquette Electronics, Milwaukee, WI. $10,000, 1993 3. Double-blind randomized study of remifentanil with propofol in patients undergoing elective in-patient surgery. Glaxo-Wellcome, Research Triangle Park, NC. $88,000, 1996 14 Charles W. Hogue, Jr., MD Curriculum Vitae 4. Phase III study of dexmedetomidine in patients undergoing coronary artery bypass graft surgery with an early extubation protocol. Abbott Labs, Abbott Park, IL $124,000, 1997 5. Frequency of myocardial ischemia in patients undergoing acute normovolemic hemodilution with either placebo or perflubron for noncardiac surgery. Robert Wood Johnson Pharmaceutical Research Institute, Rariton, NJ. $25,000, 1997 6. Comparison of remifentanil versus fentanyl for fast track protocol for patients undergoing coronary artery bypass graft surgery. Glaxo-Wellcome, Research Triangle Park, NC. $100,000, 1997 7. Safety and efficacy study of the minimum acceptable on-bypass hematocrit following treatment with perflubron or placebo during cardiopulmonary bypass. Robert Wood Johnson Pharmaceutical Research Institute, Rariton, NJ. $100,000. 8. Dex HSC#99-0416 Title: A Phase IIIb, multicenter, open-label, randomized study comparing the safety and efficacy of Dexmedetomidine to Propofol-based standard of care for ICU sedation following coronary artery bypass graft surgery. $39,685.00 9. Alexion HSC#990132 Title: A phase-II randomized, double-blind, placebo-controlled study of the effect of h5G1.1-scFv on total mortality and adverse cardiovascular ischemic outcomes in patients undergoing cardiopulmonary bypass. $129,226.00 10. Searle Study Title: Clinical protocol for evaluation of the safety and efficacy of Parecoxib 40 mg every 12 hours followed by Valdecoxib 40 mg q 12 hours in patients who have coronary artery bypass graft via median sternotomy. Protocol # I93-99-02-035. $95,000.00 11. Clinical Protocol for a Single-dose, double-blind, placebo-controlled comparison of the analgesic activity of intravenously administered Parecoxib 20 mg and Parecoxib 40 mg, Ketorolac 30 mg, Morphine 4 mg and placebo in patients who have undergone total knee replacement surgery, IND #52,613; Protocol # N93-98-02-018. $218,200.00 12. Treatment of depression after CABG surgery. National Institutes of Health. (Freedland, Kenneth, PI) 5% effort. Total Cost: $632,877; May 1, 2001- April 30, 2006 13. Estrogen for Cognitive Dysfunction after CABG surgery. National Institutes of Health (RO1 HL64600). Hogue, Charles W. Jr, MD PI, 40% effort. Total Cost: $2,153,845 July 1, 2001June 30, 2005 14. Clinical Protocol for a double-blind multicenter study of the safety and efficacy of Parecoxib followed by Valdecoxib compared to placebo for treatment of post-surgical pain in patients who have coronary bypass graft via median sternotomy. Protocol #: PARA-0505-071, Pharmacia. Total Cost: $59,477.43; 17 April 2002 15. A phase II, multi-center, placebo-controlled, randomized, stratified, double-blind, dosing regimen optimization and dose-escalation study to evaluate the safety, toleration and clinical pharmacology of zoniporide administered for up to 7 days to subjects undergoing coronary artery bypass graft (CABG) surgery. Pfizer, Inc. Direct Cost: $83,044; Overhead: $27,820; Total Cost: $98,992.25; Study Complete June 2002 15 Charles W. Hogue, Jr., MD Curriculum Vitae 16. A Double-blind placebo-controlled ascending dose study of E5564, a lipid-A antagonist, in patients undergoing cardiac surgery with cardiopulmonary bypass. Direct Costs: $37,141; Overhead: $17,733; Total Costs: $54,874; Study Complete September 2004 17. A phase-2 randomized, double-blind, placebo-controlled study of the safety and efficacy of human recombinant soluble complement receptor type-1 (TP10) in adult women undergoing cardiopulmonary bypass surgery. Avant Immunotherapeutics, Needham, MA March 2005 18. Evaluation of CleveloxTM in the perioperative treatment of hypertension assessing safety events (the ECSLIPSE Trial). The Medicines Company. March 2005 19. Response to RFA HL-06005: Network for cardiothoracic surgical investigations in cardiovascular medicine. Application sent 15 August 2006. Review February 2007. CoPrincipal Investigator (RFA guidelines specified that the PI must be a cardiac surgeon). 20. A vascular basis for neurological complications after cardiac surgery for postmenopausal women. Competing Continuation grant with planned submission of June 2007. Editorial responsibilities: 2006-Present Associate Editor-in-Chief, Anesthesia & Analgesia 2003-2006 Assistant Cardiovascular Section Editor, Anesthesia & Analgesia 2003-Present Editorial Board, Journal of Cardiothoracic & Vascular Anesthesia 2003-Present Guest Editor, Anesthesia & Analgesia Frequent reviewer: Anesthesiology; J Clin Anesthes; Ann Thoracic Surg; J Am Coll Cardiol; J Thorac Cardiovasc Surg; Stroke Books: 1999 Complications in Anesthesia, Atlee JL, (editor), Section Cardiovascular Diseases, W. B. Saunders, Co, Philadelphia, PA Editor, CLINICAL ACTIVITIES: Certification: 1990-1991 1991 1999 2003 2006 2007 Commonwealth of Massachusetts, #991267 State of Missouri, #MD R3N56 Diplomate, American Board of Anesthesiology Recertification, American Board of Anesthesiology Perioperative Transesophageal Echocardiography Maryland Board of Physicians BLS/ACLS Certification (May 19, 2007) ORGANIZATIONAL ACTIVITIES: Professional Societies and Organizations: Alpha Omega Alpha American Medical Association American Society of Anesthesiologists 16 Charles W. Hogue, Jr., MD Curriculum Vitae Association of University Anesthesiologists International Anesthesia Research Society Missouri Society of Anesthesiologists Society of Cardiovascular Anesthesiologists Examination and Committee Activities: 1991-Present Question writer ABA/ASA Joint Council In-Training Examinations 1994-Present Associate Examiner, ABA 1995-2002 American Society of Anesthesiologists Clinical Circulation Subcommittee 1997-Present American Society of Anesthesiologists Working Panel on the perioperative care of patients with pacemakers and internal cardioverter/defibrillators 2001 Expert Panel on Postoperative Atrial Fibrillation, American College of Chest Physicians, Washington, DC Data & Safety Monitoring Committee: 2003-Present Magnessium POINT Study, (1R1HL69081-02) Mark Newman, MD, PI, Duke University, Durham, NC 2005 A pilot, multicenter, randomized, double-blind, placebo-controlled study to evaluate Nesiritide infusion, initiated post-induction of anesthesia, in the management of coronary artery bypass graft (CABG) patients requiring cardiopulmonary bypass. Protocol A014. The NAPA Study. Sponsor: Scios, Inc, DSMC: Frontier Science and Technology Research Foundation Grant Reviews: The role of high-dose atorvastatin in the prevention of atrial oxidative stress, electrophysiological remodeling, and postoperative atrial fibrillation in patients undergoing cardiac surgery. British Heart Foundation. January, 2007 RECOGNITION: Honors & Awards: 1982 John Rutherford Ott Award for Outstanding Student in Biology, Southern Illinois Univ 1985 Alpha Omega Alpha, University of Illinois 1985 Otto Saphir Award for Outstanding Student in Pathology, University of Illinois 1986 Finalist, William Grove Award for Outstanding Senior, College of Medicine, Univ Illinois 1988 First Place, Resident Research Contest, Anaethesiology, Harvard Medical School 1989 Second Place, Resident Research Essay Contest, Amer Soc of Anesthesiologists 1990 Second Place, Resident Research Contest, Anesthesiology, Harvard Medical School 17 Charles W. Hogue, Jr., MD Curriculum Vitae 1990 Third Place, Resident Research Essay Contest, American Society of Anesthesiologists Invited Lectures: 1992 Anesthesia Grand Rounds, Washington University School of Medicine "Monitoring for Perioperative Myocardial Ischemia" 1992 19th Annual Symposium on Anesthesia and the Geriatric Patient Anesthesiology, Washington University School of Medicine “Muscle Relaxants in the Elderly-Are There Special Concerns?” 1993 Department of Anesthesiology, Division of Cardiothoracic Anesthesiology Washington University School of Medicine “Determinants of Cardiac Output. Principles of Hemodynamic Monitoring Symposium” 1993 Symposium, Washington, DC “Heart Rate Variability Changes During Dobutamine Stress Echocardiography Heart Rate Variability in Anesthesia” 1993 St. Louis Society of Anesthesiologists “Monitoring for Myocardial Ischemia” 1993 Department of Anesthesiology Symposium, Washington University School of Medicine “Interpretation of Invasive Hemodynamic Monitoring Anesthesia & the Geriatric Patient” 1994 Fellows Conference, Department of Medicine, Cardiovascular Division Washington University School of Medicine “Heart Rate Variability: Clinical Perspectives” 1994 Contemporary Topics in Cardiothoracic Anesthesia Division of Cardiothoracic Anesthesia Washington University School of Medicine “Anesthesia for Ventricular Tachycardia Surgery/ICD” 1994 Contemporary Topics in Cardiothoracic Anesthesia Division of Cardiothoracic Anesthesia Washington University School of Medicine “Heart Rate Variability Monitoring” 1994 3rd Congress of Anaesthesiology & Intensive Medicine. Porto Carras, Greece “Heart rate variability analysis: Potential perioperative guide to cardiac sympathovagal tone” 1994 3rd Congress of Anaesthesiology & Intensive Medicine. Porto Carras, Greece “Monitoring for Perioperative Myocardial Ischemia” 18 Charles W. Hogue, Jr., MD Curriculum Vitae 1994 4th International Heart Rate Variability Symposium San Francisco, CA “Temporal Patterns of Heart Rate Variability in Cardiac Surgical Patients and the Prognostic Capability in Patients Developing Postoperative Atrial Fibrillation” 1994 Anesthesia Grand Rounds Washington University School of Medicine “Physiologic Basis & Relationship Between Heart Rate Variability & Adverse Outcomes” 1994 Anesthesia for the Geriatric Patient Washington University School of Medicine “Heart Rate Variability-Perioperative Implications“ 1995 Current Topics in Cardiothoracic Anesthesia Washington University School of Medicine “Anesthetic Considerations for Lung Transplantation” 1995 Current Topics in Cardiothoracic Anesthesia Washington University School of Medicine “Advances in Electrocardiographic Monitoring” 1996 Kansas City Society of Anesthesiologists “Blood Conservation Strategies for Patients Undergoing Cardiac Surgery” 1996 Medical City Medical Center, Dallas, TX “Perioperative Considerations for Lung Transplantation” 1996 Topics in Cardiothoracic Anesthesia Washington University School of Medicine “Cardiac Surgery in the Elderly: What are the Outcomes?” 1996 Topics in Cardiothoracic Anesthesia Washington University School of Medicine, “Blood Substitutes as a Means of Reducing Blood Transfusions” 1996 Annual Meeting, American Society of Extra-Corporeal Technologist, Region VI “Blood Substitutes: Future Blood Sparing Strategy in Cardiac Surgical Patients?” 1997 Grand Rounds, Division of Cardiothoracic Surgery Washington University School of Medicine “Potential Perioperative Uses of Blood Substitutes in Cardiac Surgery” 1997 Current Topics in Cardiothoracic Anesthesia Washington University School of Medicine “Management & Controversies in the Management of Atrial Fibrillation after Cardiac Surgery” 1997 Current Topics in Cardiothoracic Anesthesia. 19 Charles W. Hogue, Jr., MD Curriculum Vitae Washington University School of Medicine “New Drugs for Fast Track Cardiac Anesthesia” 1997 Grand Rounds, Department of Anesthesiology Washington University School of Medicine “Potential Perioperative Uses of Blood Substitutes” 1997 Grand Rounds, Division of Cardiothoracic Surgery Washington University School of Medicine “The Emerging Role of Atherosclerosis of the Aorta in Stroke Risk after Cardiac Surgery” 1998 Contemporary Cardiothoracic Surgery, Division of Cardiothoracic Surgery Washington University School of Medicine “CNS Complications: Risk Factors and Importance to Outcome” 1998 Contemporary Cardiothoracic Surgery, Division of Cardiothoracic Surgery Washington University School of Medicine “An Update on Blood Substitutes” 1999 Wyoming Winter Anesthesia Symposium Washington University School of Medicine “Fast Track Anesthesia for Cardiac Surgery” 1999 Wyoming Winter Anesthesia Symposium Washington University School of Medicine “Clinical Pharmacology and Uses of Remifentanil” 1999 Wyoming Winter Anesthesia Symposium Washington University School of Medicine “Neurologic Outcomes Following Cardiac Surgery” 1999 Wyoming Winter Anesthesia Symposium Washington University School of Medicine “Potential Perioperative Applications of Blood Substitutes” 1999 Roundtable Discussion on Current Issues in Fast Track Cardiac Surgery, Chicago, IL “Complications of Cardiac Surgery and Failure of Fast Track Protocols” 1999 6th Annual Current Topics in Cardiothoracic Anesthesia Washington University School of Medicine “CNS Protection and Complications” 1999 6th Annual Current Topics in Cardiothoracic Anesthesia Washington University School of Medicine “Ventricular Arrhythmias” 2000 Grand Rounds, Department of Anesthesiology Washington University School of Medicine “Perioperative Arrhythmia Management” 2000 Wyoming Winter Anesthesia Symposium 20 Charles W. Hogue, Jr., MD Curriculum Vitae Washington University School of Medicine “Neuroprotection Strategies during CPB” 2000 Wyoming Winter Anesthesia Symposium Washington University School of Medicine “Perioperative Ventricular Arrhythmias” 2000 Wyoming Winter Anesthesia Symposium Washington University School of Medicine “Elective Thoracoabdominal Aneurysm” 2000 Gender & Cardiovascular Outcomes Seminar, Division of Cardiovascular Medicine Washington University School of Medicine “Neuroprotective Properties of Estrogens: Relevance for Women Undergoing Cardiac Surgery” 2000 Clinical Research Unit Research Seminar, Department of Anesthesiology Washington University School of Medicine, “Neuroprotective Strategies for Women Undergoing Cardiac Surgery” 2000 7th Annual Current Topics in Cardiothoracic Anesthesia Washington University School of Medicine “CNS Complications: Risk Factors & Importance to Outcome” 2000 Grand Rounds, Division of Cardiothoracic Surgery Washington University School of Medicine “CNS Complications after Cardiac Surgery: New Insight into Prevention” 2001 Winter Anesthesia Symposium Squaw Creek, CA “New Approaches to Life Threatening Arrhythmias” 2001 Winter Anesthesia Symposium Squaw Creek, CA “Cardiothoracic Case Conference: HITT” 2001 Winter Anesthesia Symposium Squaw Creek, CA “Improving Neuro Outcomes for Women undergoing Cardiac Surgery” 2001 Washington University School of Medicine, Department of Neurology Stroke Center Clinical Conference “Improving Neurologic Outcomes for Women undergoing Cardiac Surgery” 2001 Cardiac Catheterization Conference Missouri Baptist Hospital “Improving Neurologic Outcomes for Women undergoing Cardiac Surgery” 2001 The Cardiac Surgical Patient in the 21st Century Department of Anesthesia and Critical Care 21 Charles W. Hogue, Jr., MD Curriculum Vitae Emory University School of Medicine, “Neuroprotection for Patients Undergoing Cardiac Surgery” 2001 The Cardiac Surgical Patient in the 21st Century Department of Anesthesia and Critical Care Emory University School of Medicine, “Atrial Fibrillation in the Cardiac Surgical Patient” 2002 Anesthesia Update for Oral & Maxillofacial Surgeons & Dentists Washington University School of Medicine, “Perioperaitve Arrhythmia” 2002 Grand Rounds, Department of Anesthesiology Washington University School of Medicine “Improving Outcomes for Women Undergoing Cardiac Surgery: Is There a Role for Perioperative Estrogen Replacement” 2003 31st Annual Anesthesiology Review Course University of Alabama-Birmingham “Neuro Outcomes after Bypass Surgery” 2003 31st Annual Anesthesiology Review Course University of Alabama-Birmingham “Arrhythmia Management” 2003 Grand Rounds, Division of Cardiothoracic Surgery Washington University School of Medicine “New Insights into the Mechanism(s) of Neurologic Injury after Cardiac Surgery” 2003 Society of Cardiovascular Anesthesiology Annual Meeting Miami Beach, FL “Genetic Predisposition to Cognitive Decline Unmasked by Surgical Stressors” 2003 Society of Cardiovascular Anesthesiology Annual Meeting Miami Beach, FL “CNS Outcome after Cardiac Surgery” 2003 Society of Cardiovascular Anesthesiology Annual Meeting Miami Beach, FL “Update on the American College of Chest Physicians Practice Guidelines: Atrial Fibrillation after Cardiac Surgery” 2003 Grand Rounds, Department of Cardiology The University of Florida “Improving Outcomes for Women Undergoing Cardiac Surgery” 2004 Grand Rounds, Department of Anesthesiology Washington University School of Medicine “Neurologic Outcomes after Cardiac Surgery: Mechanisms and Prevention” 2004 Grand Rounds, Division of Cardiothoracic Surgery 22 Charles W. Hogue, Jr., MD Curriculum Vitae Washington University School of Medicine “New Insights into Neurologic Complications after Cardiac Surgery” 2005 Grand Rounds, Department of Anesthesiology Washington University School of Medicine “ACLS for the Anesthesiologist” 2005 4th Annual Update on Anesthesia for Oral Surgeons & Dentists Washington University School of Medicine “Assessing Cardiac Risk for Non-Cardiac Surgery” 2005 4th Annual Update on Anesthesia for Oral Surgeons & Dentists Washington University School of Medicine “Update on ACLS” 2006 rological complications after cardiac surgery: A translational investigative model. Research Conference, The Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medical Institutions, 15 November 2006 2006 Improving outcomes for women undergoing cardiac surgery. Grand Rounds, The Department of Anesthesiology and Critical Care Medicine The Johns Hopkins Hospital Baltimore, MD, 7 December 2006 2007 Improving outcomes for women undergoing cardiac surgery. Grand Rounds, The Division of Cardiac Surgery, The Department of Surgery, The Johns Hopkins Hospital Baltimore, MD, 1 March 2007 2007 Can we improve outcomes for women undergoing cardiac surgery? Grand Rounds, Department of Anesthesiology Washington Hospital Center Washington, DC 13 November 2007 Visiting Professorships 1997 Department of Anesthesiology and Critical Care Rush Medical College, Chicago, IL 1997 Department of Anesthesiology and Critical Care Cornell Medical School, New York, NY 1999 Department of Anesthesiology, University of Pennsylvania, Philadelphia, PA 2000 Department of Anesthesia and Critical Care Massachusetts General Hospital, Harvard Medical School, Boston, MA 2001 Department of Anesthesiology Texas Tech University, Lubbock, Texas 23 Charles W. Hogue, Jr., MD Curriculum Vitae 2001 Department of Anesthesiology Cornell Weil Medical School, New York, NY 2002 Department of Anesthesiology and Critical Care Medicine Johns Hopkins University School of Medicine, Baltimore, MD 2002 Department of Anesthesiology University of Southern California, Los Angeles, CA 2002 Department of Anesthesiology The Mayo Clinic, Rochester, MN 2003 Department of Anesthesiology The University of Florida, Gainesville, FL 2004 Division of Anesthesiology and Critical Care Cleveland Clinics, Cleveland, OH 2005 Department of Anesthesiology, Perioperative & Pain Medicine Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 2005 Medical Faculty Cork University, Cork, Ireland 2006 Department of Anesthesiology Columbia University College of Physicians & Surgeons New York, NY 2007 The Department Anesthesiology The University of Maryland Baltimore, MD 2008 The Department of Anesthesiology UCLA Los Angles, CA Presentations: Professional and Scientific Organizations 1994 Panel on Esophageal Cardiac Pacing Annual Meeting of the American Society of Anesthesiology, San Francisco, CA “Transesophageal pacing in patients with coronary artery disease” 1995 Panel on Anesthesia Management of Descending Thoracic Aortic Surgery. Annual meeting of the American Society of Anesthesiology, Atlanta, GA “Pathophysiology of Aortic Cross-Clamping” 1996 Society of Cardiovascular Anesthesia Annual meeting, Salt Lake City, UT “Cardiac Output Monitoring: Old Pitfalls/New Technologies” 24 Charles W. Hogue, Jr., MD Curriculum Vitae 1997 Cardiovascular and Thoracic Section Symposium, 54th Annual Meeting Canadian Anesthetists’ Society, Vancouver, BC, Canada “Controversy in Postoperative Atrial Arrhythmia Management” 1998 Panel on Perioperative Dysrrhythmias Society of Cardiovascular Anesthesiology Annual Meeting, Seattle, WA “Perioperative Atrial Arrhythmias after Cardiac Surgery: Patient & Economic Outcomes” 1999 Critical Care Workshop Society of Cardiovascular Anesthesia Annual Meeting, Chicago, IL “Perioperative Arrhythmia Management” 1999 Session on Pacemaker and Arrhythmia Management Society of Cardiovascular Anesthesia Annual Meeting, Chicago, IL “Post-bypass Ventricular Arrhythmias” 2000 Breakfast Symposium Society of Cardiovascular Anesthesiologists Annual Meeting, Orlando, FL “Intraoperative Ventricular Arrhythmias” 2000 Moderator: Scientific Paper Session Society of Cardiovascular Anesthesiologists Annual Meeting, Orlando, FL 2000 Moderator: Scientific Papers Poster Discussion Session Clinical Circulation: Outcomes II American Society of Anesthesiologists Annual Meeting, San Francisco, CA 2001 Prophylaxis and Management of Perioperative Atrial Fibrillation Symposium American Association of Thoracic Surgeons Annual Meeting, San Diego, CA “Atrial Fibrillation Prophylaxis in Cardiac Surgical Patients” 2001 Cardiac Arrhythmias: Drugs and Devices Panel Annual Meeting of the American Society of Anesthesiologists, New Orleans, LA “Perioperative Atrial Fibrillation/Flutter” 2002 Annual Meeting of the Society of Cardiovascular Anesthesiology, New York, NY “New Therapies for Life Threatening Perioperative Arrhythmias” 2002 Problem Based Learning Session Annual Meeting of the Society of Cardiovascular Anesthesiology, New York, NY “Atrial Fibrillation after Cardiac Surgery: Prevention and Treatment” 2002 Panel Organizer/Moderator Annual Meeting of the Society of Cardiovascular Anesthesiology, New York, NY “Implementing New Surgical Therapeutics: What Should be the “Litmus Test” for Validations” 2002 Perioperative Outcomes: Poster Discussion Moderator Annual Meeting of the Society of Cardiovascular Anesthesiology, New York, NY 25 Charles W. Hogue, Jr., MD Curriculum Vitae 2003 ASA Refresher Course Lecture Annual Meeting of the American Society of Anesthesiology “New Concepts in Antiarrhythmic Therapy” 2003 Panel: What is New in Cardiac Rhythm Management? Annual Meeting of the American Society of Anesthesiology “Prevention & Management of Perioperative Atrial Flutter & Fibrillation” 2003 Cardiovascular & Thoracic Anesthesia Clinical Forum Annual Meeting of the American Society of Anesthesiologists 2004 Annual Meeting of the International Anesthesia Research Society, Tampa, FL “Is There a Role for Routine Use of NO During Lung Transplantation” 2004 Society of Cardiovascular Anesthesia Annual Meeting, Honolulu, HI “Trends in Patient Management and Developments in Cardiovascular Medicine: Impact on the Future of Cardiovascular Anesthesia” 2004 Research Session: How to Get Your Paper Published Society of Cardiovascular Anesthesia Annual Meeting, Honolulu, HI 2004 Anesthesia & Analgesia Session Society of Cardiovascular Anesthesia Annual Meeting, Honolulu, HI 2004 Society of Cardiovascular Anesthesia Annual Meeting, Honolulu, HI “Lung Volume Reduction Surgery: A Roller Coaster Story” 2004 Refresher Course Annual Meeting of the American Society of Anesthesiologists, Las Vegas, NV “ACLS for the Anesthesiologist” 2004 Panel on Pacemakers and ICD’s Annual Meeting of the American Society of Anesthesiologists, Las Vegas, NV “Temporary Cardiac Pacing after Cardiac Surgery” 2005 Cardiology Interest Group Conference National Heart, Lung, and Blood Institute, Bethesda, MD “Pulsatile CPB for Neuroprotection” 2005 Panel on Cardiovascular Dilemmas International Anesthesia Research Society Annual Meeting, Honolulu, HI “New Onset Atrial Fibrillation” 2005 Moderator: The Neurocognitive Impact of Cardiac Surgery 22nd Spring Meeting, Assn of Cardiothoracic Anaesthetists (ACTA), Cambridge, UK 2005 Plenary Session: Neurologic Outcomes after Cardiac Surgery: Are We Making Progress Annual Meeting of the American Society of Anesthesiologists, Atlanta, GA “Pharmacologic Strategies to Avoid & Ameliorate Adverse Neurologic Sequelae after Cardiac Surgery” 26 Charles W. Hogue, Jr., MD Curriculum Vitae 2006 Common Pitfalls When Submitting A Manuscript For Review And Possible Publication. IARS Annual Meeting. San Francisco, CA March 27, 2006. Panel: Nuts And Bolts Of Writing A Scholoarly Manuscript. 2006 Safety and Efficacy of Hemostatic Agents in Clinical Practice How to Critically Evaluate Cardiac Surgery Studies Symposium, Society of Cardiovascular Anesthesia Annual Meeting 30 April, 2006 San Diego, CA 2006 Protecting the Heart during Off-Pump CABG Problem Based Learning Session Society of Cardiovascular Anesthesia Annual Meeting 1 May, 2006, San Diego, CA 2006 Moderator: Anesthesia & Analgesia Panel Society of Cardiovascular Anesthesia Annual Meeting 1 May 2006, San Diego, CA 2006 Pitfalls & Rewards of Clinical Research Society of Cardiovascular Anesthesia Annual Meeting 2 May, 2006, San Diego, CA 2006 Improving Outcomes for Women Undergoing Cardiac Surgery Association of Cardiac Anaesthetist (UK) 23 June 2006 University of Cambridge Cambridge, UK 2007 Perioperative Arrhythmia Management Refresher Course Lecture International Anesthesia Research Society Annual Meeting, Orlando, FL, 26 March 2007 2007 Antiarrhythmic Therapy Refresher Course Lecture Annual Meeting of the American Society of Anesthesiologist San Francisco, CA October 14, 2007 2007 Guidelines for the Perioperative Management of Cardiac Pacemakers Workshop on Pacemakers Annual Meeting of the American Society of Anesthesiologist San Francisco, CA October 16, 2007 2009 Cerebral Protection during Cardiac Surgery Refresher Course Lecture Annual Meeting of the American Society of Anesthesiologist San Francisco, CA October 17, 2007 27