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Eppley Seminar Series Spring 2016 Eppley Institute for Research in Cancer and Allied Diseases Eppley Science Hall Auditorium (ESH 3010) UNMC, 4220 Dewey Ave, Omaha, NE Thursday 9:00 AM DATE SPEAKER HOST TITLE Zhenkun Lou, Ph.D. Mayo Clinic, Rochester, MN Adam Karpf, Ph.D. Ubiquitination and the DNA Damage Response Yujiang Shi, Ph.D. Brigham and Women’s Hospital, Harvard Medical School Jing (Jenny) Wang, Ph.D. Deregulation of Epigenetic Barrier in Cancer Dmitry Gordenin, Ph.D. National Institute of Environmental Health Sciences Youri Pavlov, Ph.D. Hypermutation in Human Cancer March 3 Kenneth P. Nephew, Ph.D. Indiana University Ken Cowan, M.D./Ph.D Hypomethylating Agents and Episensitization in Cancer March 10 Tracy A. Brooks, Ph.D. University of Mississippi Jennifer Black, Ph.D. kRas G-quadruplex regulation Gangning Liang, M.D., Ph.D. Keck School of Medicine of USC Adam Karpf, Ph.D. Yong Wan, Ph.D. University of Pittsburgh Jing (Jenny) Wang, Ph.D. Senthil Muthuswamy, Ph.D., University of Toronto Kay-Uwe Wagner, Ph.D. April 7 Alan Fields, Ph.D. Mayo Clinic, Jacksonville, FL Jennifer Black, Ph.D. Protein Kinase C iota: A Multi-lineage Oncogene in the Lung April 14 S. Perwez Hussain, Ph.D. NIH Pankaj Singh, Ph.D. MIF Signaling as a Pathogenic Driver and Potential Target in Pancreatic Cancer April 28 Charles Mullighan, MBBS (Hons), MSc, M.D. St. Jude Children’s Research Hospital Michael Green, Ph.D. Redefining the genetic taxonomy of acute lymphoblastic leukemia: implications for pathogenesis, diagnosis and therapy May 5 Narendra Wajapeyee, Ph.D. Yale Pankaj Singh, Ph.D. Genetic Vulnerability Pathways in Cancer Jan 21 Feb 4 Feb 25 March 17 March 24 March 31 Gene Body Methylation is a Therapeutic Target in Cancer Posttranslational Modifications in Genome Stability and Carcinogenesis Cell Polarity and Tumor Organoids: New Pathways and Models for Controlling Cancer UNMC faculty, staff and students are invited to attend the presentation. Meeting Coordinator: Misty Pocwierz, 402 559-4092