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***Please note that this review sheet is by no means comprehensive, but instead is intended as a guidleline. You will be responsible for any material that was viewed in class, presented in lectures, or provided in your text. Final exam review sheet RDAs: EAR, AI, UL, DRI; AMDR Major/minor minerals, nutrients, energy obtained from each Diseases: marasmus, kwashiorkor, cystic fibrosis, sickle cell anemia, phenylketonuria, pellagra, beriberi, rickets, celiac disease, GERD, irritable bowel, diabetes I and II, lactose intolerance, macrocytic anemia, anorexia, bulimia, osteoporosis Proteins, carbohydrates and lipids Be able to distinguish the structures Understand how each is digested (and enzymes involved) General functions of each in the body AMDRs, RDAs Blood sugar regulation Terms: transcription, translation, location in cell of each Protein structure and denaturation “good” vs “bad” cholesterol: LDLs, VLDLs, HDLs Digestion, Absorption, Elimination Know anatomy (eg, sphincters, organs) Hormones involved, organs that produce them Metabolism Terms: anabolism, catabolism Glucose metabolism: glycolysis, Kreb’s cycle, electron transport chain Important molecules: glucose, pyruvate, lactic acid, acetyl coA, citrate, oxaloacetate, NAD+ and FAD+ (in both reduced/oxidized forms), ATP Reactions: phosphorylation, oxidation, reduction, condensation (dehydration), hydrolysis Fatty acid oxidation, carnitine, acetyl coA Vitamins involved in glucose/fat metabolism Gluconeogenesis Nitrogen excretion after deamination Ketogenesis, ketoacidosis Energy production (ATPs), electron carriers Vitamins/Minerals Water soluble vs. Fat soluble vitamins, major/trace minerals General function of each Deficiencies Functions of fluids in the body Sweating Intra- vs. Extra- cellular fluids (and associated electrolytes) Function of electrolytes Antioxidants: which vitamins/mineral(s); generally how antioxidants work Bone: cells, PTH, vitamin D, calcitriol, osteoporosis Disordered Eating vs. eating disorders Traits associated with each, physiological repercussions of each Appetite vs. hunger Body composition, BMI, total energy expenditure, BMR, thrifty gene theory, set-point theory, leptin, ghrelin, peptide YY, obesity, gastric bypass Physical activity Understand how the body utilizes energy reserves Governmental recommendations for physical fitness Overload principle, FIT, BMR, BMI Pregnancy/Lactation Development of baby from conceptionfetus Dietary needs of newborn Roles of Oxytocin, prolactin, estrogen and progesterone Dietary needs of lactating mother Toddlers, preschoolers, school-aged kids, adolescents, older adults Dietary needs (macro- and micronutrient trends), childhood overweight vs. obesity, epiphyseal plates and adolescent growth Alcohol metabolism Drink equivalents, proof, Alcohol dehydrogenase, aldehyde dehydrogenase (ethanolacetylaldehydeacetic acidacetyl coA), MEOS pathway, effects of alcohol on the body (brain, liver, pancreas, upper GI), hangover Food safety Food additives (and examples of), food preservatives (and examples of), pesticides, governmental agencies regulation/role of each, food infections vs. intoxications (and examples provided in lecture for each), food allergies, prevention of food borne illness, prevention of food spoilage, persistent organic pollutants, rBGH, governmental definitions of organic, GMOs, Modern Meat Good luck!