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ANESTHESIA By Alaina Darby INHALATION ANESTHESIA Which of the following does not include altered mental state? a. Analgesia b. Anxiolysis c. Sedation d. Anesthesia Which of the following includes blockade of mental, motor, and sensory input and reflexes? a. Analgesia b. Anxiolysis c. Sedation d. Anesthesia Which of the following may or may not result in loss of protective reflexes? a. Analgesia b. Anxiolysis c. Sedation d. Anesthesia Which of the following is a reason for using IV over PO for anesthesia? a. Better control over sedation depth b. Better control over sedative duration of action c. Greater bioavailability of IV sedatives d. Better efficacy of IV sedation What is the MAC? a. Concentration of solubilized anesthetic needed to render all patients unconscious b. Concentration of solubilized anesthetic needed to render half of patients unconscious c. Concentration of IV anesthetic needed to render all patients unconscious d. Concentration of IV anesthetic needed to render half of patients unconscious Which of the following is a result of increased lipid solubility of anesthetics? a. Increased MAC, increased potency b. Decreased MAC, increased potency c. Increased MAC, decreased potency d. Decreased MAC, decreased potency Which of the following is always true of lipid solubility and the oil gas partition coefficient? a. The larger the oil gas partition coefficient, the higher the potency b. The smaller the oil gas partition coefficient, the higher the potency c. The larger the oil gas partition coefficient, the lower the solubility d. The smaller the oil gas partition coefficient, the lower the solubility Which of the following is true of the Meyer-Overton hypothesis? a. It is always true because anesthetic activity always decreases with lipid solubility b. It is usually true because anesthetic activity usually decreases with lipid solubility c. It is always true because anesthetic activity always increases with lipid solubility d. It is usually true because anesthetic activity usually increases with lipid solubility When would the Meyer-Overton hypothesis not be true? a. Lipophilic molecules that are large will not produce substantial anesthesia b. Lipophilic molecules that are small will not produce substantial anesthesia c. Lipophilic molecules that are large can still produce substantial anesthesia d. Lipophilic molecules that are small can still produce substantial anesthesia Decrease in activity at which of the following receptors/channels can produce anethesia? a. GABA b. NMDA c. Glycine d. K+ 2 pore channels Which of the following has little effect on NMDA receptors? a. Nitrous oxide b. Isoflurane c. Sevoflurane d. Desflurane Activity in which of the following parts of the brain is most dramatically decreased with anesthesia? a. Frontal b. Parietal c. Occipital d. Temporal Activity in which of the following parts of the brain is preserved with anesthesia? a. Frontal b. Parietal c. Occipital d. Temporal Which of the following is seen with initial anesthesia administration? a. Decreased blood pressure b. Decreased muscle tone c. Increased delirium d. Increased intercostal respiration Which of the following types of neurons is inhibited first anesthesia administration? a. Inhibitory neurons b. Stimulatory neurons c. Sympathetic neurons d. Parasympathetic neurons Which of the following increases with increased anesthesia? a. Muscle tone b. Diaphragmatic respiration c. Intercostal respiration d. Blood pressure Which of the following reflexes is the last to be affected? a. Swallow reflex b. Pupil light reflex c. Eyelid reflexes d. Laryngeal reflexes Which of the following is most likely to be preserved before analgesia is produced? a. Memory b. Perceptive awareness c. Response to pain d. Autonomic reactions Which of the following is the reason that halogens are added to volatile agents? a. Make them less damaging to the kidney b. Make them less damaging to the liver c. Make them less explosive d. Increase efficacy Which of the following comprises the majority of inhalation anesthesia? a. Oxygen b. Nitrous oxide c. Volatile anesthetic d. Carbon dioxide Which of the following varies between the blood and alveoli? a. Anesthetic concentration b. Anesthetic pressure c. Anesthetic tension d. Anesthetic volume Which of the following is the most potent agent? a. Halothane b. Isoflurane c. Sevoflurane d. Nitrous oxide Which of the following cannot be used alone for anesthesia? a. Halothane b. Isoflurane c. Sevoflurane d. Nitrous oxide What is not a reason that nitrous oxide is added to inhalation anesthesia? a. Synergism b. High potency c. Maintain protective reflex d. Decreased expense Which of the following is not associated with increased potency? a. Higher MAC b. Higher percent as metabolites c. Higher lipophilicity d. Higher protein binding Which of the following causes an inhalation anesthetic to have a faster recovery? a. Decreased lipophilicity b. Increased onset c. Increased duration d. Increased plasma availability Which of the following is not a major pathway for anesthetic movement? a. From alveoli to arterial blood b. From arterial blood to brain c. From alveoli to venous blood d. From brain to venous blood Which of the following equilibrates the most quickly? a. Liver b. Brain c. Skeletal muscles d. Fat Increasing ventilation rate has the most profound effect to increase delivery of which of the anesthetics? a. Nitrous oxide because it must saturate a larger volume of blood b. Nitrous oxide because it must saturate a smaller volume of blood c. Halothane because it must saturate a larger volume of blood d. Halothane because it must saturate a smaller volume of blood