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Paramedic Care: Principles & Practice Fourth Edition Volume 4: Medicine CHAPTER 3 Neurology Multimedia Directory Slide Slide Slide Slide Slide Slide 15 16 117 119 126 138 Reuptake Inhibitor Animation L-Dopa Animation Epilepsy Video Grand Mal Seizure Video Complex Partial Seizure Video Diazepam Animation ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Standard • Medicine (Neurology) ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Competency • Integrates assessment findings with principles of epidemiology and pathophysiology to formulate a field impression and implement a comprehensive treatment/disposition plan for a patient with a medical complaint. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Introduction • Strokes attack 795,000 people every year; 150,000 die. • Epilepsy affects 3 million people. • 50,000 Americans diagnosed with Parkinson's disease each year. • People affected by headache, multiple sclerosis, syncope, neoplasm, other nervous system emergencies. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Anatomy and Physiology • Nervous system is body's principal control system. • Network of cells, tissues, organs regulates nearly all bodily functions via electrical impulses transmitted through nerves. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Anatomy and Physiology • Endocrine system: related to nervous system; exerts control via hormones. • Circulatory system: assists in regulatory functions by distributing hormones and chemical messengers. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Anatomy and Physiology • Central nervous system (CNS): brain and spinal cord. • Peripheral nervous system (PNS): – Somatic nervous system: voluntary functions. – Autonomic nervous system: sympathetic and parasympathetic nervous system; involuntary physiologic processes. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Anatomy and Physiology • Think of nervous system as a “living computer.” • CNS is central processing unit • Various divisions of PNS carry on input and output processes. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Anatomy and Physiology • The Central Nervous System – Neuron: fundamental unit of nervous system; nerve cell. Cell body (soma): contains nucleus. Dendrites: transmit electrical impulses to cell body. Axons: transmit electrical impulses away from cell body. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Anatomy of a neuron. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Anatomy and Physiology • The Central Nervous System – In resting state, neuron positively charged on outside; negatively charged on inside. – When electrically stimulated, sodium rapidly surges into cell and potassium rapidly leaves it to eliminate difference in electrical charge between inside and outside. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Anatomy and Physiology • The Central Nervous System – This “depolarization,” or loss of charge difference, is transmitted down neuron at extremely high rate of speed. – Neuron joins with other neurons at junctions called synapses. – Axon causes release of chemical neurotransmitter (acetylcholine or norepinephrine). ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Anatomy and Physiology • The Central Nervous System – Neurotransmitter stimulates postsynaptic membrane of connecting nerve. – Acetylcholine: neurotransmitter of parasympathetic and voluntary (somatic) nervous systems. – Norepinephrine: found in synaptic terminals of sympathetic nerves. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Reuptake Inhibitor Animation Click here to view an animation on the topic of reuptake inhibitors. Back to Directory ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. L-Dopa Animation Click here to view an animation on the topic of l-dopa. Back to Directory ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Anatomy and Physiology • The Central Nervous System – Brain within cranial vault, protected by skull. – Covered by the scalp, cranium consists of bones of head, excluding facial bones. Frontal and occipital bones. Parietal, temporal, sphenoids, ethmoids. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. The bones of the skull (cross section). ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. The bones of the skull (profile). ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Anatomy and Physiology • The Central Nervous System – 33 bones constitute the spine. 7 cervical vertebrae 12 thoracic vertebrae 5 lumbar vertebrae 5 sacral vertebrae 4 coccygeal vertebrae – Spinal cord housed inside; protected by “spinal canal” formed by these bones. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. The vertebral column. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Anatomy and Physiology • The Central Nervous System – Meninges: protective membranes cover entire CNS. Dura mater: durable, outermost layer. Arachnoid membrane: middle layer; weblike structure. Pia mater: innermost layer, directly overlying CNS. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Anatomy and Physiology • The Central Nervous System – Both brain and spinal cord bathed in cerebrospinal fluid; watery, clear fluid that acts as cushion. – Brain largest part of CNS. – Brain divided into six major parts: Cerebrum, diencephalon, pons, mesencephalon, medulla oblongata, cerebellum. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Anatomy and Physiology • The Central Nervous System – Cerebrum Governs all sensory and motor actions. Intelligence, learning, analysis, memory, language. Cerebral cortex outermost layer of cerebrum. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Anatomy and Physiology • The Central Nervous System – Diencephalon (interbrain) Inside are thalamus, hypothalamus, limbic system. Involuntary actions: temperature regulation, sleep, water balance, stress response, emotions. Major role in regulating autonomic nervous system. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Anatomy and Physiology • The Central Nervous System – Mesencephalon (midbrain), pons, and medulla oblongata collectively form brainstem; brainstem and cerebellum constitute hindbrain. – Mesencephalon: responsible for certain aspects of motor coordination. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Anatomy and Physiology • The Central Nervous System – Pons: connection between brain and spinal cord. – Medulla oblongata: center for controlling respiration, cardiac activity, vasomotor activity. – Cerebellum: coordinates fine motor movement, posture, equilibrium, muscle tone. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Anatomy and Physiology • The Central Nervous System – Speech: located in temporal lobe of cerebrum. – Vision: located in occipital cortex of cerebrum. – Personality: located in frontal lobes of cerebrum. – Balance and coordination: located in cerebellum. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Anatomy and Physiology • The Central Nervous System – Sensory: located in parietal lobes of cerebrum. – Motor: located in frontal lobes of cerebrum. – Reticular activating system: responsible for maintaining consciousness and ability to respond to stimuli. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. External anatomy of the brain. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Anatomy and Physiology • The Central Nervous System – Brain receives about 20% of body's total blood flow per minute. – Accounts for only 2% of body weight. – Consumes 25% of body's glucose. – Carotid system anterior; vertebrobasilar system posterior; both join at circle of Willis. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Anatomy and Physiology • The Central Nervous System – Besides blood flow, cerebrospinal fluid bathes brain and spinal cord. – Several chambers within brain (ventricles) contain most of intracranial volume of this fluid. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Anatomy and Physiology • The Central Nervous System – Spinal cord 17–18 inches long. – Responsible for conducting impulses to and from peripheral nervous system and for reflexes. – Thirty-one pairs of nerve fibers exit spinal cord as it descends and enters PNS. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Sectional view of the spinal cord showing distribution of spinal nerves. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Anatomy and Physiology • The Central Nervous System – Afferent (sensory) fibers transmit impulses to CNS from body. – Efferent (motor) fibers carry impulses from CNS to body. – Each nerve root has corresponding area of skin (dermatome) to which it supplies sensation. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Anatomy and Physiology • The Central Nervous System – Reflexes are protective. – Spinal cord stimulates appropriate muscles to remove part of body closest to perceived threat. – Reflex actions lack fine motor control. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Anatomy and Physiology • The Peripheral Nervous System – Consists of cranial and peripheral nerves; both voluntary and involuntary components. – 12 pairs of cranial nerves originate in brain; supply nervous control to head, neck, certain thoracic and abdominal organs. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Anatomy and Physiology • The Peripheral Nervous System – Somatic sensory: afferent nerves transmit sensations involved in touch, pressure, pain, temperature, position. – Somatic motor: efferent fibers carry impulses to skeletal (voluntary) muscles. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Anatomy and Physiology • The Peripheral Nervous System – Visceral (autonomic) sensory: afferent tracts transmit sensations from visceral organs. – Visceral (autonomic) motor: efferent fibers exit CNS and branch to supply nerves to involuntary cardiac muscle and smooth muscle of viscera (organs) and to glands. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Anatomy and Physiology • The Automatic Nervous System – Involuntary component of PNS: responsible for unconscious control of many body functions. – Sympathetic and parasympathetic systems are antagonistic. – During stress, sympathetic system dominates; during rest, parasympathetic system dominates. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Anatomy and Physiology • The Sympathetic Nervous System – Referred to as “fight-or-flight” system. – Prepares body for stressful situations. – Stimulation causes increased heart rate and blood pressure, pupillary dilation, rise in blood sugar, bronchodilation. – Neurotransmitters epinephrine and norepinephrine mediate its actions. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Anatomy and Physiology • The Parasympathetic Nervous System – “Feed-or-breed” system; responsible for controlling vegetative functions (normal heart rate and blood pressure). – Mediated by acetylcholine. – When stimulated: decrease in heart rate, increase in digestive activity, pupillary constriction, reduction in blood glucose. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Pathophysiology • Consciousness: individual fully responsive to stimuli and demonstrates awareness of environment. • Altered forms of consciousness can result from dysfunction or interruption of CNS. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Pathophysiology • Central Nervous System Disorders – Alteration in mental status hallmark sign of CNS injury or illness. – Any alteration in mental status is abnormal; warrants examination. – Unconsciousness (coma): patient cannot be aroused, even by powerful external stimuli. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Pathophysiology • Central Nervous System Disorders – Structural lesions: depress consciousness by destroying or encroaching on substance of brain. Brain tumor (neoplasm) Degenerative disease Intracranial hemorrhage Parasites Trauma ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Pathophysiology • Central Nervous System Disorders – Toxic-metabolic states: presence of circulating toxins or metabolites or lack of metabolic substrates. Anoxia Diabetic ketoacidosis Hepatic failure Hypercapnia Hypoglycemia ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Pathophysiology • Central Nervous System Disorders – Toxic-metabolic states Renal failure Thiamine deficiency Toxic exposure ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Pathophysiology • Altered Mental Status Common Causes – Drugs Depressants (including alcohol) Hallucinogens Narcotics ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Pathophysiology • Altered Mental Status Common Causes – Cardiovascular Anaphylaxis Cardiac arrest Stroke Arrhythmias Hypertensive encephalopathy Shock ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Pathophysiology • Altered Mental Status Common Causes – Respiratory Chronic obstructive pulmonary disease (COPD) Inhalation of toxic gas Hypoxia ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Pathophysiology • Altered Mental Status Common Causes – Infectious AIDS Encephalitis Meningitis Parasites ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Pathophysiology • Autonomic nervous system (ANS): maintains cerebral homeostasis (internal balance); regulates and coordinates body's vital functions. – Blood pressure – Temperature regulation – Respiration – Metabolism ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Pathophysiology • Peripheral Nervous System Disorders – Peripheral neuropathy: any malfunction or damage of peripheral nerves. – Can affect muscle activity, sensation, reflexes, internal organ function. – Mononeuropathy caused by localized conditions (trauma, compression, infections). ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Pathophysiology • Peripheral Nervous System Disorders – Polyneuropathy: demyelination or degeneration of peripheral nerves. Leads to sensory, motor, or mixed sensorimotor deficits. Causes: immune disorders, toxic agents, metabolic disorders. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Pathophysiology • Autonomic Nervous System Disorders – Frequently result of another condition. – Most conditions that affect integrity of individual are accompanied by some changes in autonomic nervous system functioning. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. General Assessment Findings • Size up scene and surroundings as well as patient to form general impression. • Evaluate mental status before assessing ABCs. – General appearance – Speech – Skin – Posture/gait ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. General Assessment Findings • Quickly check patient's mental status through “AVPU” method. – A: patient alert and aware of surroundings. – V: patient responds to verbal stimuli. – P: patient responds to painful stimuli. – U: patient unresponsive. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. General Assessment Findings • Assess patient's emotional status. – Alteration from normal mental status or mood considered significant; warrants additional assessment. Mood Thought Perception Judgment Memory and attention ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. General Assessment Findings • Once level of consciousness determined, place greatest emphasis on maintenance of airway. • If unconscious, assume cervical spine injury exists; treat appropriately. – Use modified jaw-thrust maneuver. – Once opened, insert appropriate airway adjunct. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. General Assessment Findings • In unresponsive, tongue may be occluding airway. – Place oropharyngeal or nasopharyngeal airway to maintain patency. • Essential to observe for respiratory arrest that can result from increased intracranial pressure. • Remain alert for absent gag reflex and vomiting. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. General Assessment Findings • Observe for signs and symptoms of inadequate or impaired breathing or abnormal respiratory patterns. • Evaluate heart rate, rhythm, electrocardiogram (ECG) pattern. • Observe skin color, temperature, moisture. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. General Assessment Findings • Secondary assessment: history and physical exam, including vital signs. • Determine whether neurologic problem traumatic or medical. – Clarification will determine plan for subsequent prehospital treatment. – Obtain information from family, friends, or other bystanders. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. General Assessment Findings • Physical examination: standard headto-toe examination; more detailed neurologic assessment. – Pay particular attention to pupils, respiratory status, spinal evaluation. – Note any drooping or facial paralysis. – If both pupils dilated and do not react to light, patient probably has brainstem injury or suffered serious brain anoxia. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. General Assessment Findings • Physical Examination – Unilaterally dilated pupil that remains reactive to light may be sign of increasing intracranial pressure. – Constricted (pinpoint) pupils suggest toxic etiology for altered mental status. – Assess extraocular movement: have patient follow finger movements. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. General Assessment Findings • Physical Examination – Important to check for contact lenses. – Pay particular attention to any changes that potentially compromise airway. – Respiratory derangement can occur with CNS illness or injury. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. General Assessment Findings • Abnormal Respiratory Patterns – Cheyne-Stokes respirations – Kussmaul's respirations – Central neurogenic hyperventilation – Ataxic respirations – Apneustic respirations ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. General Assessment Findings • Physical Examination – Normal blood PaCO2 is 40 mmHg. – Increasing PaCO2 causes cerebral vasodilation; decreasing it results in cerebral vasoconstriction. – Patients with neurologic dysfunction have worse outcomes when excessive oxygen (hyperoxia) administered. – Assess the SpO2. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. General Assessment Findings • Physical Examination – Vigilant assessment of vital signs to observe following changes: Heart rate ECG/rhythm Bruits Jugular venous distention (JVD) ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. General Assessment Findings • Nervous System Status – Sensorimotor evaluation: document loss of sensation and/or motor function. – Suspected spinal cord injury will require full immobilization on long spine board. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. General Assessment Findings • Nervous System Status – Both decorticate and decerebrate posturing are ominous signs of deep cerebral or upper brainstem injury. – Flaccid paralysis indicates spinal cord injury. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Patient with decorticate posturing. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Patient with decerebrate posturing. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. General Assessment Findings • Motor System Status – Assessment Muscle tone Strength Flexion Extension Coordination Balance ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. General Assessment Findings • Cranial nerves: proper and intact functioning assessed during complete neurologic examination. • Glasgow coma scale (GCS); total score indicator of survival. – Eye opening – Verbal response – Motor response ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. General Assessment Findings • Vital Signs – Increased intracranial pressure: changes in vital signs (Cushing's triad). Increased blood pressure Decreased pulse Irregular respirations – Continuous ECG monitoring and pulse oximetry to spot early signs of CNS lesions. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. General Assessment Findings • Capnography: monitors amount of carbon dioxide being exhaled by patient while being ventilated. • Pulse oximeter: tool for monitoring patient's general state of perfusion. • Blood glucose meter: obtain accurate blood glucose level. • CO-oximetry: detection of elevated CO levels possible in prehospital setting. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. General Assessment Findings • Geriatric Considerations – Neurologic system susceptible to systemic illness and often by other body disorders. – Level of consciousness and mental status evaluated by assessing judgment, memory, affect, mood, orientation, speech, grooming. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. General Assessment Findings • Geriatric Considerations – Interview family members. – Problems: headache, low back pain, dizziness, weakness, loss of balance, disorders such as Parkinson's disease, and vascular emergencies such as stroke. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. General Assessment Findings • Any patient suffering from neurologic emergency should be reassessed every 5 minutes during your care and during transportation. • Constantly reevaluate and monitor airway and neurologic system. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Primary treatment for nervous system emergencies in field is supportive. – Airway and breathing – Circulatory support – Pharmacological interventions – Psychological support – Transport considerations ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Altered Mental Status – AEIOU-TIPS A = Acidosis, alcohol E = Epilepsy I = Infection O = Overdose U = Uremia (kidney failure) ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Altered Mental Status – AEIOU-TIPS T = Trauma, tumor, toxin I = Insulin (hypoglycemia or diabetic ketoacidosis) P = Psychosis, poison S = Stroke, seizure ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Altered Mental Status – Determine underlying cause. – Determine level of consciousness. – Unresponsive patients require vigilant monitoring and protection of airway. – Initial priority: ensure airway open and cervical spine immobilized. – Assess circulatory status. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Altered Mental Status – Establish IV with saline lock. – Determine blood glucose level. – If blood glucose level low, administer 50% dextrose. – Administer naloxone if suspected narcotic overdose. – If suspected alcoholic, consider administration of 100 mg of thiamine. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Altered Mental Status – Chronic alcoholism interferes with intake, absorption, use of thiamine. – Wernicke's syndrome: acute but reversible encephalopathy; ataxia, eye muscle weakness, mental derangement. – Korsakoff's psychosis: memory disorder; may be irreversible. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Altered Mental Status – Increase in intracranial pressure: ventilate patient at 10–12 breaths per minute. – Mannitol causes diuresis. – As with all medications, follow local protocols. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Stroke and Intracranial Hemorrhage – Stroke (brain attack): injury or death of brain tissue usually due to interruption of cerebral blood flow. – Early recognition and rapid transport to hospital crucial to improving outcome for stroke patients. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Stroke and Intracranial Hemorrhage – Tissue plasminogen activator (tPA) and fibrinolytic agents effective in treating certain occlusive strokes. – Third most common cause of death; frequent cause of disability. – Serious, potentially life-threatening condition. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Stroke and Intracranial Hemorrhage – Occlusive stroke: cerebral artery blocked by clot or other foreign matter. Results in ischemia, an inadequate blood supply to brain tissue. Progresses to infarction, death of tissues as result of cessation of blood supply. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Causes of stroke. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Stroke and Intracranial Hemorrhage – Embolic strokes: embolus is solid, liquid, or gaseous mass carried to blood vessel from remote site. – Emboli are clots (thromboemboli); arise from diseased blood vessels in neck (carotid) or abnormally contracting chambers in heart. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Stroke and Intracranial Hemorrhage – Other types of emboli that cause occlusion in cerebral blood vessels: air, tumor tissue, fat. – Embolic strokes occur suddenly; characterized by severe headaches. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Stroke and Intracranial Hemorrhage – Thrombotic strokes: cerebral thrombus is blood clot that gradually develops in and obstructs cerebral artery. – Atherosclerosis Plaque deposits form on inner walls of arteries; buildup causes narrowing of arteries; reduces amount of blood that can flow through them. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Stroke and Intracranial Hemorrhage – Signs and symptoms of thrombotic stroke develop gradually. – Often occurs at night; characterized by patient awakening with altered mental status and/or loss of speech, sensory, or motor function. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Stroke and Intracranial Hemorrhage – Hemorrhagic strokes: categorized as being within brain (intracerebral) or in space around outer surface of brain (subarachnoid). – Onset often sudden; marked by severe headache. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Stroke and Intracranial Hemorrhage – Most intracranial hemorrhages occur in hypertensive patient when small vessel deep within brain tissue ruptures. – Subarachnoid hemorrhages most often result from congenital blood vessel abnormalities or from head trauma. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Etiologies of stroke. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Stroke and Intracranial Hemorrhage – Signs and symptoms of stroke will depend on type of stroke and area of brain damaged. – Areas commonly affected: motor, speech, sensory centers. – Onset of symptoms will be acute; patient may experience unconsciousness. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Signs and symptoms of stroke include: – Facial drooping – Headache – Confusion and agitation – Dysphasia – Aphasia – Dysarthria ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Signs and symptoms of stroke include: – Vision problems such as monocular blindness or double vision – Hemiparesis – Hemiplegia – Paresthesia – Inability to recognize by touch ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Signs and symptoms of stroke include: – Gait disturbances or uncoordinated fine motor movements – Dizziness – Incontinence – Coma ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Stroke and Intracranial Hemorrhage – Predisposing factors: Hypertension Diabetes Abnormal blood lipid levels Oral contraceptives Sickle cell disease Some cardiac arrhythmias (atrial fibrillation) ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Prehospital Stroke Scoring Systems – Los Angeles Prehospital Stroke Screen (LAPSS) Assesses blood glucose levels, facial droop, grip strength, arm (pronator) drift. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Facial droop. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Arm drift. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Prehospital Stroke Scoring Systems – Cincinnati Prehospital Stroke Scale (CPSS) Evaluates facial droop, arm drift, speech. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Stroke and Intracranial Hemorrhage – Transient ischemic attacks (TIAs): transient stroke-like symptoms. Temporary interference with blood supply to brain, producing symptoms of neurologic deficit. Last for few minutes or for several hours; usually resolve within 24 hours. No evidence of residual brain or neurologic damage. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Stroke and Intracranial Hemorrhage – Patient who experiences TIA may be a candidate for eventual stroke. – Considered high-risk events. – Onset usually abrupt. – Any one or combination of stroke symptoms may be present. – Common cause is carotid artery disease. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Stroke and Intracranial Hemorrhage – Suspected of TIA Previous neurologic symptoms Initial symptoms and their progression Changes in mental status Precipitating factors Dizziness ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Stroke and Intracranial Hemorrhage – Suspected of TIA Palpitations History of hypertension, cardiac disease, sickle cell disease, previous TIA or stroke ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Stroke and Intracranial Hemorrhage – Care for stroke or TIA Early recognition Supportive measures Rapid transport Notification of emergency department Aggressive airway management is priority ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Stroke and Intracranial Hemorrhage – Care for stroke or TIA Ensure scene safety, including Standard Precautions. Establish and maintain adequate airway. If apneic or if breathing inadequate, provide positive pressure ventilations at rate of 10–12 per minute. Check for hypoxia with pulse oximetry. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Stroke and Intracranial Hemorrhage – Care for stroke or TIA Complete detailed patient history. Perform stroke assessment. Keep patient supine or in recovery position. Determine blood glucose level. Place saline lock. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Stroke and Intracranial Hemorrhage – Care for stroke or TIA Monitor cardiac rhythm, oximetry, capnography. Protect paralyzed extremities. Give patient reassurance. Rapidly transport. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Types of Seizures – Generalized: begin as electrical discharge in small area of brain but spread to involve entire cerebral cortex, causing widespread malfunction. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Types of Seizures – Partial: may remain confined to limited portion of brain, causing localized malfunction, or may spread and become generalized. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Epilepsy Video Click here to view a video on the topic of epileptic seizures. Back to Directory ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Types of Seizures – Generalized seizures include tonic-clonic and absence seizures. – Tonic-clonic (grand mal seizure): generalized motor seizure, producing loss of consciousness. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Grand Mal Seizure Video Click here to view a video on the topic of grand mal seizures. Back to Directory ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Types of Seizures – Tonic (increased tone) phase: tensed, contracted muscles – Clonic phase: rhythmic jerking movements of extremities. – Specific progression of events. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Types of Seizures – Tonic-clonic seizures have specific progression of events: Aura Loss of consciousness Tonic phase; hypertonic phase Clonic phase Post seizure Postictal ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Types of Seizures – Absence (petit mal seizure): brief, generalized seizure; 10- to 30-second loss of consciousness or awareness, eye or muscle fluttering, occasional loss of muscle tone. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Types of Seizures – Pseudoseizures (hysterical seizures): stem from psychological disorders. – Patient presents with sharp and bizarre movements that can often be interrupted with terse command. – Very rarely do patients experiencing pseudoseizure injure themselves. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Types of Seizures – Partial seizures: simple or complex. Simple partial seizures (focal motor, focal sensory, or Jacksonian seizures): chaotic movement or dysfunction of one area of body. No loss of consciousness; frequently spread. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Types of Seizures – Partial seizures: simple or complex. Complex partial (temporal lobe or psychomotor seizures):distinctive auras. Unusual smells, tastes, sounds, or tendency of objects to look very large and near or small and distant. Metallic taste in mouth common. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Complex Partial Seizure Video Click here to view a video on the topic of complex partial seizures. Back to Directory ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Types of Seizures – Ascertain exactly what patient may recall or what bystanders witnessed. – Many other problems can mimic or suggest seizure. – If unsure whether patient had seizure, it may be more harmful than beneficial to administer anticonvulsant medication. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Types of Seizures – Distinguish between syncope and true seizure. – History of seizures. – Recent history of head trauma. – Any alcohol and/or drug abuse. – Recent history of fever, headache, stiff neck. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Types of Seizures – History of diabetes, heart disease, or stroke. – Current medications. – Note signs of head trauma or injury to tongue. – Determine blood glucose level. – Check for hypoxia. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Types of Seizures – Note any evidence of alcohol and/or drug abuse. – Document arrhythmias. – Ensure scene safety. – Maintain airway. – Administer supplemental oxygen to correct hypoxia. – Establish intravenous access. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Types of Seizures – Determine blood glucose level. – Never attempt to restrain patient. – Maintain body temperature. – Position patient on left side after tonicclonic phase. – Suction, if required. – Monitor cardiac rhythm, oximetry, capnography. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Protection of a seizing patient. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Place a seizing patient with no suspected spine injury on her left side. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Types of Seizures – If seizure prolonged (> 5 minutes), consider anticonvulsant. – Provide quiet, reassuring atmosphere. – Transport patient in supine or lateral recumbent position. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Types of Seizures – Status epilepticus: series of two or more generalized motor seizures without intervening return of consciousness. Common cause: failure to take prescribed anticonvulsant medications. Involves prolonged period of apnea; can cause hypoxia of vital brain tissues. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Types of Seizures – Status epilepticus Protect patient from airway obstruction; deliver 100% oxygen. Start IV of normal saline, keep-open rate. Monitor cardiac rhythm, oximetry, capnography. Administer 25 g of 50% dextrose IV push. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Types of Seizures – Status epilepticus Administer 5–10 mg diazepam IV push for adult. Continue to monitor airway. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Diazepam Animation Click here to view an animation on the topic of diazepam. Back to Directory ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Syncope (fainting): neurologic condition; sudden, temporary loss of consciousness caused by insufficient blood flow to brain; recovery of consciousness on becoming supine. – Cardiovascular conditions – Hypovolemia – Noncardiovascular disease – Idiopathic, or unknown cause ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Syncope (fainting) – Identify underlying cause and treat it. – Ensure scene safety. – Establish and maintain adequate airway. – Administer supplemental oxygen to correct hypoxia. Avoid hyperoxia. – Check circulatory status. – Check and monitor mental status. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Syncope (fainting) – Obtain IV access. – Determine blood glucose level. – Monitor ECG, oximetry, capnography. – Reassure patient. – Transport to emergency department. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Headache – Can be acute (sudden onset); chronic (constant or recurring); generalized (all over); localized (in one specific area). – Can range from mild to severe. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Headache – Vascular headaches include migraines and cluster headaches. – Significant percentage are tension headaches. – Organically caused headaches. – Continuous throbbing headache with fever, confusion, nuchal rigidity classic signs and symptoms of meningitis. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Headache – Complaints of nausea, vomiting, blurred vision, dizziness, weakness, watery eyes. – Complete and thorough history crucial to treatment. – Headache of acute onset or of changing pattern demands immediate attention. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Headache – Ensure scene safety. – Establish and maintain adequate airway. – Place patient in position of comfort. – Administer supplemental oxygen to correct hypoxia. Avoid hyperoxia. – Obtain IV access. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Headache – Determine blood glucose level. – Monitor ECG, oximetry, capnography. – Reassure patient. – Consider antiemetics or pain-control measures. – Ensure calm, quiet environment. – Transport to emergency department. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Cranial Nerve Disorders – Affects connection between cranial nerve centers of brain and particular tissues innervated by those nerves. – Signs and symptoms depend on nerve involved. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Cranial Nerve Disorders – Bell's palsy: sudden, unilateral weakness or paralysis of facial muscles; due to dysfunction of seventh cranial nerve (facial nerve). Treatment: antiviral drugs. In most instances, resolves completely without any residual deficits. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Bell's palsy. (© Michal Heron) ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Cranial Nerve Disorders – Trigeminal neuralgia (tic doloureux): extremely painful disorder that affects fifth cranial nerve (trigeminal nerve). Electrical-shock-type spasms and pain. Tends to be chronic condition. Antiseizure drugs used in treatment. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Weak and Dizzy – Can be symptoms of many diseases. – Obtain more detailed history of illness. – Focused assessment, including neurologic examination. – Be alert for presence of nystagmus. – Determine if localized or diffuse. – Be alert for potential causes. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Weak and Dizzy – Ensure scene safety. – Establish and maintain adequate airway. – Place patient in position of comfort, generally with head elevated. – Administer supplemental oxygen to correct hypoxia. Avoid hyperoxia. – Obtain IV access. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Weak and Dizzy – Check blood glucose level. – Monitor ECG, oximetry, capnography. – Consider administration of antiemetic. – Consider analgesic therapy with opiate. – Ensure calm, quiet environment. – Reassure patient. – Transport to emergency department. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Neoplasms – New growth of tumor. – Benign (noncancerous) tumors: composed of cells that grow similarly to normal cells, grow relatively slowly, confined to one location. – Malignant (cancerous) tumors: growth very different from that of normal cells; grow quickly and spread to other sites. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Neoplasms – Any tumor located near any of vital structures of brain may seriously threaten ability to breathe, move, or regulate other bodily functions. – Most brain tumors metastases from cancer that started somewhere else in body. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Signs and Symptoms of Neoplasm – Headache (often severe and recurring frequently) – New seizures in adult with no history of seizure disorder – Nausea – Vomiting – Behavioral or cognitive changes ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Signs and Symptoms of Neoplasm – Weakness or paralysis or change in sensation of one or more limbs or side of face – Lack of coordination – Difficulty walking or unsteady gait – Dizziness – Double vision ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Neoplasms – Ensure scene safety. – Establish and maintain adequate airway. – Place patient in position of comfort, generally with head elevated. – Administer supplemental oxygen to correct hypoxia. – Obtain IV access. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Neoplasms – Monitor ECG, oximetry, capnography. – Consider narcotic analgesia. – Consider diazepam if seizure activity is present. – Anti-inflammatories (dexamethasone) and diuretics may be requested by medical direction. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Neoplasms – Ensure calm, quiet environment. – Reassure patient. – Transport to emergency department. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Brain Abscess – Collection of pus localized in area of brain; uncommon. – Headache, lethargy, hemiparesis, seizures, nuchal rigidity, nausea, vomiting, fever. – Management: supportive. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Degenerative Neurologic Disorders and Dementia – Collection of diseases; selectively affect one or more functional systems of CNS. – Alzheimer's disease Results from death and disappearance of nerve cells in cerebral cortex; marked atrophy of brain. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Degenerative Neurologic Disorders and Dementia – Pick's disease Permanent form of dementia similar to Alzheimer's disease Tends to affect only certain areas of brain; rare. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Degenerative Neurologic Disorders and Dementia – Huntington's disease (Huntington's chorea) Caused by genetic defect in chromosome 4; adult-onset and early-onset types. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Degenerative Neurologic Disorders and Dementia – Creutzfeldt-Jakob disease (CJD) Form of brain damage; leads to rapid decrease in mental function and movement. Results from protein called prion; rare. There is no treatment. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Degenerative Neurologic Disorders and Dementia – Muscular dystrophy (MD) Group of genetic diseases characterized by progressive muscle weakness and degeneration of skeletal or voluntary muscle fibers. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Degenerative Neurologic Disorders and Dementia – Multiple sclerosis (MS) Unpredictable disease of CNS. Inflammation of certain nerve cells followed by demyelination, or destruction, of myelin sheath. Nerves unable to properly conduct impulses. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Degenerative Neurologic Disorders and Dementia – Guillain-Barré syndrome Serious disorder. Body's defense (immune) system mistakenly attacks peripheral nerves, leading to nerve inflammation that causes muscle weakness. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Degenerative Neurologic Disorders and Dementia – Dystonias Group of disorders; muscle contractions cause twisting and repetitive movements, abnormal postures, freezing in middle of action. Such movements involuntary and sometimes painful. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Degenerative Neurologic Disorders and Dementia – Parkinson's disease Belongs to group of conditions known as motor system disorders. Chronic and progressive disorder. Four characteristics: tremor, rigidity, bradykinesia, postural instability. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Degenerative Neurologic Disorders and Dementia – Central pain syndrome Results from damage or injury to brain, brainstem, or spinal cord. Intense, steady pain; burning, aching, tingling, “pins-and-needles” sensation. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Degenerative Neurologic Disorders and Dementia – Amyotrophic lateral sclerosis (ALS) (Lou Gehrig's disease) Progressive degeneration of specific nerve cells that control voluntary movement. Motor neuron disease. There is no cure. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Degenerative Neurologic Disorders and Dementia – Myoclonus Temporary, involuntary twitching or spasm of muscle or group of muscles. Considered not diagnosis but symptom. Treatment: medications to reduce symptoms. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Degenerative Neurologic Disorders and Dementia – Spina bifida (SB) Neural defect; results from failure of one or more of fetal vertebrae to close properly during pregnancy. Leaves portion of spinal cord unprotected. Nerve damage permanent; no cure. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Degenerative Neurologic Disorders and Dementia – Spina bifida (SB) common types Myelomeningocele Meningocele Occulta ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Degenerative Neurologic Disorders and Dementia – Poliomyelitis (polio) Infectious, inflammatory viral disease of CNS that sometimes results in permanent paralysis. New cases rare. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Assessment of Degenerative Neurologic Disorders – Determine chief complaint. – Conduct primary assessment. – Correct any life-threatening problems. – Find out what prompted call to EMS. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Management of Degenerative Neurologic Disorders – Treat chief complaint as priority. – Consider the following: Mobility Communication Respiratory compromise Anxiety ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Management of Degenerative Neurologic Disorders – Determine blood glucose level. – Obtain IV access. – Monitor ECG. – Transport to emergency department. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Back Pain and Nontraumatic Spinal Disorders – Low back pain (LBP): most common back pain complaint; can be debilitating. – Felt between lower rib cage and gluteal muscles, often radiating to thighs. – Sciatica: severe pain along path of sciatic nerve, down back of thigh and inner leg. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Back Pain and Nontraumatic Spinal Disorders – Nontraumatic spinal injuries Degeneration or rupture of disks that separate vertebrae. Degeneration or fracture of vertebrae. Cyst or tumor that impinges on spine. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Back Pain and Nontraumatic Spinal Disorders – Disk injury Cartilaginous disks that separate vertebrae may rupture as result of injury or rupture or degenerate as part of aging. Herniated disk: gelatinous center of disk extrudes through tear in outer capsule. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Back Pain and Nontraumatic Spinal Disorders – Vertebral injury Vertebrae themselves break down (vertebral spondylolysis). Heredity a factor. Spinal fractures frequently associated with osteoporosis. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Back Pain and Nontraumatic Spinal Disorders – Cyst or tumor along spine or intruding into spinal canal may cause pain by pressing on spinal cord, by causing degenerative changes in bone, or by interrupting blood supply. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Back Pain and Nontraumatic Spinal Disorders – Cauda equina syndrome Significant narrowing of spinal canal that compresses nerve roots below level of spinal cord. Trauma, disk herniation, spinal stenosis, spinal tumors, inflammation, infection. Decompressive surgery often necessary. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Back Pain and Nontraumatic Spinal Disorders – Referred pain: from disorders such as diabetic neuropathy, renal calculus, abdominal aortic aneurysm, many other conditions. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Back Pain and Nontraumatic Spinal Disorders – Assessment based on chief complaint, history, physical exam. – Precise diagnosis likely difficult. – Determine if pain caused by lifethreatening or non-life-threatening condition. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Management of Specific Nervous System Emergencies • Back Pain and Nontraumatic Spinal Disorders – Prehospital management Aimed at decreasing pain or discomfort. Keep watchful eye for signs and symptoms of serious underlying disorder. If in doubt, immobilize, remembering the injunction to “do no harm.” ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Summary • Nervous system can be thought of as complex system of computer processors (CNS) and wiring (PNS) responsible for entirety of body functions. • When abnormality occurs, signs and symptoms include reduced ability or inability to complete task or function that otherwise would normally occur. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Summary • Brain is the control center for all functions of body. • Whenever there is interruption in blood supply to any part of brain, result will be inability to perform associated function or functions. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Summary • EMS personnel should know the 12 cranial nerves, or, at minimum, how to assess each one. • Thorough neurologic assessment of all 12 cranial nerves helps to quickly identify abnormalities and even specific area of brain affected. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Summary • In all neurologic emergencies, it is imperative to address airway and oxygenation first, followed closely by general assessment, making sure to use available diagnostic tools. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Summary • Keep in mind that the brain is largely powered by glucose and oxygen. • If the level of either of these becomes altered, the patient is likely to present with neurologic symptoms. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Summary • Your first assessment tools should include blood glucose assessment and pulse oximetry. • Always treat hypoglycemia in neurologically impaired patients, because often hypoglycemia is the cause and is easily corrected with dextrose. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Summary • Neurologic emergencies often present with altered level of consciousness up to and including coma. • Rapid identification and treatment of possible causes (AEIOU-TIPS) with rapid transport to closest appropriate facility is imperative. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Summary • For neurologic impairment (especially for stroke), treatment is very time sensitive (definitive treatment must occur within 4.5 hours from onset). • Rapid treatment is essential for best possible outcomes. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Summary • Whether you are treating a possible stroke, seizure, coma, or headache, your treatment must remain focused on assessing and maintaining patient's airway, oxygen, and glucose levels. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Summary • Rapid identification and early notification to your receiving facility are key in achieving successful recovery from strokes and other neurologic impairments. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed. Summary • Often, care for neurologic patient may simply be supportive; in other cases, you will need to provide drug therapy or other interventions to limit or reduce presenting symptoms. • In every case, airway management remains your priority. ©2013 Pearson Education, Inc. Paramedic Care: Principles & Practice, 4th Ed.