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PREGNANCY AND THE PHARMACIST SOME WORDS OF WISDOM Dr. Yoel Abells Some Do’s and Don’ts • Do – Be extra patient with the patient; – Remember the power of language • Don’t – Forget that pregnancy is a multi-phased event • Do – Remember folic acid Some Do’s and Don’ts Continued... • Don’t – Immediately choose meds; – Consider non-medicinal options • Do – Consult (attending; motherisk) • Don’t – CPS everything Nausea and Vomiting • Dry foods in AM • Small frequent meals • Avoid strong/precipitating smells • Avoid heavy/greasy/spicy foods • Consider DiclectinTM (doxylamine and vitamin B6) Gastric Reflux and Heartburn • Avoid eating 2 hours before bedtime • Avoid precipitating foods (greasy/spicy/heavy/other) • Elevate head of bed • Consider medications (magnesium and aluminum hydroxide-eg Maalox; alginic compounds- eg. Gaviscon; calcium carbonate-eg. Tums; histamine H2-receptor antagonists-eg. Zantac; GI cytoprotective agents-eg. Sulcrate and bismuth subsalicylate) Aches and Pains •Rest/heat/stretching/other •Massage/other •Consider medications (acetaminophen, aspirin and NSAIDs-not third trimester, TCA’s benzo’s, codeine and dimenhydrinate for migraines) Constipation • Increased fluids • Increased dietary fibre • Commercial fibre supplement (metamucil) • Consider medications (mineral oil, docusate sodium/calcium-colace/surfak, glycerin, lactulose, bisacodyl-dulcolax, etc.) Skin Conditions 1) acne • Cleansers • Topical erythromycin/clindamycin • Oral erythromycin 2) pruritis • Moisturizers • Consider medications (topical eg. calamine lotion, steroid creams, local anaesthetics; oral eg. hydroxyzine, diphenhydramine, steroids) Other Odds and Ends 1) Allergies • consider specific symptomatic treatment (see below) • consider systemic treatment (diphenhydramine/Benadryl; chlorpheniramine/Chlor-Trilpolon) 2) Congestion • steam • saline drops (Otrivin, Saline/Salinex) • consider medications (oxymethazoline/Dristan; xylomethazoline/Otrivin; cromolyn; etc.) 3) Cough • fluids • steam • consider medications (dextromethorphan/Benylin-DM; codeine) More Odds and Ends 4) Fever • rest, reassurance • consider medications (acetaminophen) 5) Sore throat • fluids, fluids, fluids • candy/lozenges 6) Sun protection • avoid over exposure • sunscreen More Odds and Ends 7) Insect bite prevention • stay in at worst times • avoid endemic areas • avoid perfumes (etc.) and wear light coloured long clothes • use sprays with less than 30% DEET and spray on clothes and exposed skin 8) Avoid/limit • alcohol • caffeine (3 or less cups/day) • hair colours/perms • natural products • sweeteners • tobacco Supplemental reading: • Mazzotta P, Magee LA. A risk-benefit assessment of pharmacological and nonpharmacological treatments for nausea and vomiting of pregnancy. Drugs 2000;59: 781800.